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    Bioinformatics

    Bioinformatics: an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformatics combines computer science, statistics, mathematics, and engineering to analyze and interpret biological data.

    Webinars

    • MAY 13, 2015 | 1:30 PM
      Agilent platform for genomics, transcriptomics, proteomics and metabolomics based integrated biology: challenges and tools for multi-omics research
      Agilent platform for genomics, transcriptomics, proteomics and...
      Biological datasets have become increasing large and complex. Knowledge databases and publicly available datasets are available for use in experimental planning and running results comparison...
      Speaker: Carolina Livi, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      5
      MAY 13, 2015 | 12:00 PM
      Dissecting the diagnostic yield of exome sequencing
      Dissecting the diagnostic yield of exome sequencing
      Technological advances in high throughput, low cost DNA sequencing coupled with the availability of a high quality reference assembly allow us to interrogate the genome with greater precision...
      Speaker: Deanna Church, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      2
      MAY 13, 2015 | 10:30 AM
      Transcriptome Assembly: Computational Challenges of Next-Generation Sequence Data
      Transcriptome Assembly: Computational Challenges of Next-Generation...
      Next-generation sequencing technology allows us to peer inside the cell in exquisite detail, revealing new insights into biology, evolution, and disease that would have been impossible to dis...
      Speaker: Steven Salzberg, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
      MAY 13, 2015 | 10:30 AM
      Statistical methods for bulk and single-cell RNA-seq experiments
      Statistical methods for bulk and single-cell RNA-seq experiments
      I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
      Speaker: Christina Kendziorski, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4 1
      MAY 13, 2015 | 10:30 AM
      Population Scale Human Genome Analysis on the Cloud
      Population Scale Human Genome Analysis on the Cloud
      Advanced sequencing technologies have made population scale whole genome sequencing a possibility. However, current strategies for analysis of this data rely upon parallelization approaches t...
      Speaker: Peter White, PhD, James Hirmas
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
      MAY 13, 2015 | 7:30 AM
      Keynote: Big Data in Health Care and Biomedical Research
      Keynote: Big Data in Health Care and Biomedical Research
      Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      0 1
      MAY 11, 2015 | 1:00 PM
      Isolation and characterization of exosomes and ectosomes
      Isolation and characterization of exosomes and ectosomes
      Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that are released t...
      Speaker: Suresh Mathivanan, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      17 5
      APR 16, 2015 | 8:00 AM
      Advances in Sedimentation Analysis
      Advances in Sedimentation Analysis
      In recent years, sophisticated new methods for sedimentation data analysis have opened up new avenues for leveraging AUC technology in a wide range of technology sectors, including life scien...
      Speaker: Borries Demeler, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      12 1
      MAR 04, 2015 | 8:00 AM
      Diversity of extracellular vesicles and their cargo in cell-to-cell communication
      Diversity of extracellular vesicles and their cargo in cell-to-cell...
      Every cell in the body can release several types of extracellular vesicles (EVs), often called ”exosomes” or ”microvesicles”. These vesicles carry a wide array of mole...
      Speaker: Jan Olof Lötvall, MD, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      30
      OCT 30, 2014 | 6:00 AM
      A platform for combining the results of WES and RNA-seq analysis
      A platform for combining the results of WES and RNA-seq analysis
      Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
      Speaker: Naomi Thomson
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 7:30 AM
      Making Clinical NGS possible
      Making Clinical NGS possible
      Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
      Speaker: Vikram Devgan, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 02, 2014 | 7:00 AM
      Make new discoveries - with Qlucore's visualization based software
      Make new discoveries - with Qlucore's visualization based software
       Within the field of bioinformatics, scientists and organizations struggle with multiple problems. Key problems are the large amount of data and that the people who understand biology (or che...
      Speaker: Magnus Fontes, PhD
      Sponsored By: Qlucore, Qlucore
      29
      SEP 24, 2014 | 11:00 AM
      Drug Repositioning in the Era of Personalized Medicine
      Drug Repositioning in the Era of Personalized Medicine
      This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
      Speaker: Craig Webb, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      32
      SEP 16, 2014 | 10:00 AM
      Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
      Expanded clinical research opportunities for Crizotinib identified...
      Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
      Speaker: Sean Eddy, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      12
      SEP 16, 2014 | 9:30 AM
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
      Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
      Speaker: Nickolay Khazanov, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      18
      SEP 16, 2014 | 8:30 AM
      The use of transcriptional signatures for clinical population selection
      The use of transcriptional signatures for clinical population...
      The use of biomarkers for the stratification of populations for therapy is a concept that holds the potential to revolutionize clinical trial design, the economics of healthcare, and most imp...
      Speaker: Mary Ellen Urick, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      18
      SEP 16, 2014 | 8:00 AM
      Overview
      Overview
      ...
      Speaker: Emma Bowden, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      6
      SEP 10, 2014 | 10:00 AM
      NGS Lessons in Translational Diagnostics
      NGS Lessons in Translational Diagnostics
      In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
      Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
      Sponsored By: Asuragen, Asuragen
      48
      AUG 21, 2014 | 9:45 AM
      Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
      Pathway based analyses for genetic susceptibility to cancer and...
      In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      62
      AUG 21, 2014 | 8:45 AM
      Genome and exome sequencing in a clinical laboratory
      Genome and exome sequencing in a clinical laboratory
      With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
      Speaker: Matthew Lebo, PhD, FACMG
      Presented at: Genetics and Genomics Virtual Event Series 2014
      30
      AUG 20, 2014 | 2:15 PM
      Identifying transcriptional regulators of human embryonic development via expression variability
      Identifying transcriptional regulators of human embryonic development...
      Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 12:30 PM
      Integrative Systems Approaches to Network Modeling of Biological Processes
      Integrative Systems Approaches to Network Modeling of Biological...
      ...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      44
      AUG 20, 2014 | 8:45 AM
      Novel gene chip technologies and NGS sequencing for personalized medicine & diagnostic
      Novel gene chip technologies and NGS sequencing for personalized...
      The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
      Speaker: Dani Bercovich, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 8:30 AM
      Actionable mutation detection with multiplex pcr-based targeted enrichment approach for next generation sequencing (NGS)
      Actionable mutation detection with multiplex pcr-based targeted...
      Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
      Speaker: Vikram Devgan, PhD, MBA
      Presented at: Genetics and Genomics Virtual Event Series 2014
      16
    MAY 13, 2015 | 1:30 PM
    Agilent platform for genomics, transcriptomics, proteomics and metabolomics based integrated biology: challenges and tools for multi-omics research
    Agilent platform for genomics, transcriptomics, proteomics and...
    Biological datasets have become increasing large and complex. Knowledge databases and publicly available datasets are available for use in experimental planning and running results comparison...
    Speaker: Carolina Livi, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    5
    MAY 13, 2015 | 12:00 PM
    Dissecting the diagnostic yield of exome sequencing
    Dissecting the diagnostic yield of exome sequencing
    Technological advances in high throughput, low cost DNA sequencing coupled with the availability of a high quality reference assembly allow us to interrogate the genome with greater precision...
    Speaker: Deanna Church, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    2
    MAY 13, 2015 | 10:30 AM
    Transcriptome Assembly: Computational Challenges of Next-Generation Sequence Data
    Transcriptome Assembly: Computational Challenges of Next-Generation...
    Next-generation sequencing technology allows us to peer inside the cell in exquisite detail, revealing new insights into biology, evolution, and disease that would have been impossible to dis...
    Speaker: Steven Salzberg, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
    MAY 13, 2015 | 10:30 AM
    Statistical methods for bulk and single-cell RNA-seq experiments
    Statistical methods for bulk and single-cell RNA-seq experiments
    I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
    Speaker: Christina Kendziorski, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4 1
    MAY 13, 2015 | 10:30 AM
    Population Scale Human Genome Analysis on the Cloud
    Population Scale Human Genome Analysis on the Cloud
    Advanced sequencing technologies have made population scale whole genome sequencing a possibility. However, current strategies for analysis of this data rely upon parallelization approaches t...
    Speaker: Peter White, PhD, James Hirmas
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
     
     
  • MAY 13, 2015 | 7:30 AM
    Keynote: Big Data in Health Care and Biomedical Research
    Keynote: Big Data in Health Care and Biomedical Research
    Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    0 1
    MAY 11, 2015 | 1:00 PM
    Isolation and characterization of exosomes and ectosomes
    Isolation and characterization of exosomes and ectosomes
    Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that are released t...
    Speaker: Suresh Mathivanan, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    17 5
    APR 16, 2015 | 8:00 AM
    Advances in Sedimentation Analysis
    Advances in Sedimentation Analysis
    In recent years, sophisticated new methods for sedimentation data analysis have opened up new avenues for leveraging AUC technology in a wide range of technology sectors, including life scien...
    Speaker: Borries Demeler, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    12 1
    MAR 04, 2015 | 8:00 AM
    Diversity of extracellular vesicles and their cargo in cell-to-cell communication
    Diversity of extracellular vesicles and their cargo in cell-to-cell...
    Every cell in the body can release several types of extracellular vesicles (EVs), often called ”exosomes” or ”microvesicles”. These vesicles carry a wide array of mole...
    Speaker: Jan Olof Lötvall, MD, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    30
    OCT 30, 2014 | 6:00 AM
    A platform for combining the results of WES and RNA-seq analysis
    A platform for combining the results of WES and RNA-seq analysis
    Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
    Speaker: Naomi Thomson
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
     
     
  • OCT 29, 2014 | 7:30 AM
    Making Clinical NGS possible
    Making Clinical NGS possible
    Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
    Speaker: Vikram Devgan, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 02, 2014 | 7:00 AM
    Make new discoveries - with Qlucore's visualization based software
    Make new discoveries - with Qlucore's visualization based software
     Within the field of bioinformatics, scientists and organizations struggle with multiple problems. Key problems are the large amount of data and that the people who understand biology (or che...
    Speaker: Magnus Fontes, PhD
    Sponsored By: Qlucore, Qlucore
    29
    SEP 24, 2014 | 11:00 AM
    Drug Repositioning in the Era of Personalized Medicine
    Drug Repositioning in the Era of Personalized Medicine
    This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
    Speaker: Craig Webb, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    32
    SEP 16, 2014 | 10:00 AM
    Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
    Expanded clinical research opportunities for Crizotinib identified...
    Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
    Speaker: Sean Eddy, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    12
    SEP 16, 2014 | 9:30 AM
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
    Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
    Speaker: Nickolay Khazanov, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    18
     
     
  • SEP 16, 2014 | 8:30 AM
    The use of transcriptional signatures for clinical population selection
    The use of transcriptional signatures for clinical population...
    The use of biomarkers for the stratification of populations for therapy is a concept that holds the potential to revolutionize clinical trial design, the economics of healthcare, and most imp...
    Speaker: Mary Ellen Urick, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    18
    SEP 16, 2014 | 8:00 AM
    Overview
    Overview
    ...
    Speaker: Emma Bowden, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    6
    SEP 10, 2014 | 10:00 AM
    NGS Lessons in Translational Diagnostics
    NGS Lessons in Translational Diagnostics
    In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
    Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
    Sponsored By: Asuragen, Asuragen
    48
    AUG 21, 2014 | 9:45 AM
    Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
    Pathway based analyses for genetic susceptibility to cancer and...
    In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    62
    AUG 21, 2014 | 8:45 AM
    Genome and exome sequencing in a clinical laboratory
    Genome and exome sequencing in a clinical laboratory
    With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
    Speaker: Matthew Lebo, PhD, FACMG
    Presented at: Genetics and Genomics Virtual Event Series 2014
    30
     
     
  • AUG 20, 2014 | 2:15 PM
    Identifying transcriptional regulators of human embryonic development via expression variability
    Identifying transcriptional regulators of human embryonic development...
    Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    AUG 20, 2014 | 12:30 PM
    Integrative Systems Approaches to Network Modeling of Biological Processes
    Integrative Systems Approaches to Network Modeling of Biological...
    ...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    44
    AUG 20, 2014 | 8:45 AM
    Novel gene chip technologies and NGS sequencing for personalized medicine & diagnostic
    Novel gene chip technologies and NGS sequencing for personalized...
    The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
    Speaker: Dani Bercovich, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    AUG 20, 2014 | 8:30 AM
    Actionable mutation detection with multiplex pcr-based targeted enrichment approach for next generation sequencing (NGS)
    Actionable mutation detection with multiplex pcr-based targeted...
    Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
    Speaker: Vikram Devgan, PhD, MBA
    Presented at: Genetics and Genomics Virtual Event Series 2014
    16
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