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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
MAY 03, 2018 | 11:00 AM
DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
MAY 02, 2018 | 8:00 AM
Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
APR 27, 2018 | 10:00 AM
DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
APR 26, 2018 | 8:00 AM
DATE: April 26, 2018TIME: 8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
APR 25, 2018 | 7:00 AM
DATE: April 25, 2018TIME: 1500 CET, 10:00 a.m. EST, 7:00 a.m. PST Hematology and coagulation laboratories perform a wide range of routine and specialized tests, allowing clinicians to...
APR 17, 2018 | 8:00 AM
DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
APR 12, 2018 | 10:30 AM
In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
APR 11, 2018 | 12:00 PM
Screening for Down syndrome began with the question "How old will you be when you deliver?". If the pregnant woman answered 35 years of age or older, she was offered amniocent...
APR 11, 2018 | 10:30 AM
Historically single cell isolation techniques suffered from poor efficiency, low recovery and difficult automation, among other limitations. This presentation will highlight cellenONE, a piez...
APR 06, 2018 | 9:00 AM
DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
MAR 29, 2018 | 12:00 PM
It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
MAR 29, 2018 | 9:00 AM
Studies have demonstrated how cannabis may contribute to cancer treatment not only by treating symptoms but also by: cancer cell apoptoss, anti-proliferation, anti-metastatic and anti-angioge...
MAR 28, 2018 | 10:00 AM
DATE: March 28, 2018TIME: 10:00am PDT, 01:00pm EDTPrimary cells are derived from various tissues typically via dissection, enzymatic dissociation, and subsequent culture in media specif...
MAR 27, 2018 | 9:00 AM
DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
MAR 27, 2018 | 9:00 AM
DATE: March 27, 2018TIME: 09:00am PST, 12:00pm EST...
MAR 22, 2018 | 9:00 AM
DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
MAR 21, 2018 | 8:00 AM
DATE: March 21, 2018TIME: 8:00AM PST, 11:00AM ESTMass cytometry, or cytometry by time-of-flight (the basis of the CyTOF® system), enables quantification of the abundance and fu...
MAR 15, 2018 | 10:30 AM
The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
MAR 15, 2018 | 9:00 AM
Monitoring protein biomarkers in cerebrospinal fluid (CSF) of patients with Alzheimer’s Disease (AD) has been highly beneficial to understanding disease progression. While several...
