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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • FEB 22, 2017 | 10:30 AM
      NGS live in your lab in 30 days
      NGS live in your lab in 30 days
      Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
      Speaker: Salim Essakali , Yi Kong, Ph.D.
      Presented at: Precision Medicine Virtual Event Series 2017
      2 2
      FEB 22, 2017 | 10:30 AM
      Beyond the hype: the evidence behind the role of genetics in drug response
      Beyond the hype: the evidence behind the role of genetics in drug...
      Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
      Speaker: Matt Nelson, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      5
      FEB 22, 2017 | 6:00 AM
      Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
      Mate-pair next generation sequencing as a powerful clinical tool...
      Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      FEB 21, 2017 | 11:00 AM
      Genome Engineering to Introduce a Fluorescent Reporter into Human Pluripotent Stem Cells to Study Cardiac Disease
      Genome Engineering to Introduce a Fluorescent Reporter into Human...
      The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
      Speaker: Lise Munsie, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      FEB 20, 2017 | 8:00 AM
      Tips, hints and trouble shooting: optimization of your recombinant protein preparation workflow
      Tips, hints and trouble shooting: optimization of your recombinant...
      First established in the 1880’s, cell culture is the process by which cells are grown in a laboratory under controlled environment. The culturing of different kinds of cells supports sc...
      Speaker: Quangvu Nguyen
      Presented at: Protein Research Live
      5
      FEB 20, 2017 | 8:00 AM
      Presenting a complete workflow - from start to finish!
      Presenting a complete workflow - from start to finish!
      The CRISPR-Cas9 system is being widely used for genome engineering in many different biological applications. It was originally adapted from the bacterial Type II CRISPR system and uses a Cas...
      Speaker: Emily Anderson, Ph.D.
      Presented at: Protein Research Live
      4
      FEB 09, 2017 | 3:00 PM
      Education/Training/CPD from the Chinese perspective
      Education/Training/CPD from the Chinese perspective
      DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
      Speaker: Wanyong (William) Pang, BVM, MS, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 09, 2017 | 6:00 AM
      Continuous Professional Development (CPD) in Laboratory Animal Science, a continuous improvement in animal welfare and science
      Continuous Professional Development (CPD) in Laboratory Animal...
      DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThere is no professional area in which CPD is more necessary than in the field of laboratory animals. The continuous advancement of scien...
      Speaker: Patri Vergara, DVM, PhD, DipECLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
      FEB 08, 2017 | 1:30 PM
      Safety and pharmacokinetic profiles of different buprenorphine SR doses in a rabbit model
      Safety and pharmacokinetic profiles of different buprenorphine...
      DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
      Speaker: Andrea Zanetti, DVM, PhD, SRS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
      FEB 08, 2017 | 1:30 PM
      Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
      Characterization of Niemann Pick Type C mutant mice using automated...
      DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
      Speaker: Sangeetha Iyer, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      1
      FEB 08, 2017 | 10:30 AM
      Biosecurity, Reproductive and Social Management of Cat Research Colonies
      Biosecurity, Reproductive and Social Management of Cat Research...
      DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
      Speaker: James Kehler VMD, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      JAN 27, 2017 | 4:00 AM
      WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity Through Time and Space by Mass Cytometry
      WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity...
      DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
      Speaker: Bernd Bodenmiller, PhD , Randall Wetzel, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      16
      JAN 19, 2017 | 8:00 AM
      Webinar: Detecting meaningful mutations from liquid biopsies by Anchored Multiplex PCR
      Webinar: Detecting meaningful mutations from liquid biopsies by...
      DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
      Speaker: Josh Stahl , Jonathan Doose
      Sponsored By: ArcherDX, ArcherDX
      9
      JAN 17, 2017 | 8:00 AM
      Regulation of Bivalent Domains by Histone Modifications
      Regulation of Bivalent Domains by Histone Modifications
      Bivalent domains are thought to be controversial, yet crucial,  regulatory hubs in the differentiation of stem cells. Listen in as  Dr Philipp Voigt of the Wellcome Trust Centre for...
      Speaker: Philipp Voigt, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      JAN 17, 2017 | 8:00 AM
      Single-Cell RNA-Seq and cell heterogeneity in the central nervous system
      Single-Cell RNA-Seq and cell heterogeneity in the central nervous...
      Recent advances in single-cell RNA sequencing are producing exciting new insights into cell diversity within different tissues and cancers. Listen in to hear  Dr Gonçalo Castelo-B...
      Speaker: Gonçalo Castelo-Branco, PhD , Amit Zeisel, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      5
      JAN 17, 2017 | 8:00 AM
      Benefits and limitations of primary and secondary antibody conjugates
      Benefits and limitations of primary and secondary antibody conjugates
      Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
      Speaker: Javier Vancells, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      JAN 17, 2017 | 8:00 AM
      An Introduction to In-Cell ELISA
      An Introduction to In-Cell ELISA
      In-Cell ELISA, is a well-accepted assay approach to perform quantitative immunocytochemistry of cultured cells using either a colormetric or fluorometric readout.  Join our In-Cell ELISA...
      Speaker: John Constable, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      DEC 14, 2016 | 7:30 AM
      Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
      Advances in modeling human diseases using induced pluripotent...
      DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
      Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      7 1
      DEC 07, 2016 | 9:00 AM
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
      Speaker: Edgar Jacoby, Ph.D.
      Sponsored By: DiscoverX, DiscoverX
      4
      DEC 06, 2016 | 11:00 AM
      Expansion of Human Stem Cells in BioBLU Single-Use Vessels from Eppendorf
      Expansion of Human Stem Cells in BioBLU Single-Use Vessels from...
      DATE: December 6, 2016 TIME: 11:00am PT, 2:00pm ET Experimentation involving human stem cells (HSCs) is one of the fastest growing fields in research and development due, in large part, t...
      Speaker: Stacey Willard, PhD
      Sponsored By: Eppendorf, Eppendorf
      5 1
      DEC 01, 2016 | 8:00 AM
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
      DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
      Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
      Sponsored By: Revvity
      3
      NOV 23, 2016 | 8:00 AM
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
      Speaker: Moritz Voelker-Albert , Andreas Schmidt
      Sponsored By: SCIEX OMICS, SCIEX OMICS
      24
      NOV 17, 2016 | 3:00 PM
      Molecular elucidation and engineering of stem cell fate decisions
      Molecular elucidation and engineering of stem cell fate decisions
      Stem cells play critical roles in the development of organisms, as well as in the maintenance and repair of organs and tissues throughout adulthood.  Advancing our understanding of mecha...
      Speaker: David Schaffer, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      NOV 17, 2016 | 1:00 PM
      Initiatives to advance stem cell science and medicine at California's $3 billion stem cell agency
      Initiatives to advance stem cell science and medicine at California's...
      The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs.  With $3 billion in funding and 300 a...
      Speaker: Stephen Lin, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
    FEB 22, 2017 | 10:30 AM
    NGS live in your lab in 30 days
    NGS live in your lab in 30 days
    Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
    Speaker: Salim Essakali , Yi Kong, Ph.D.
    Presented at: Precision Medicine Virtual Event Series 2017
    2 2
    FEB 22, 2017 | 10:30 AM
    Beyond the hype: the evidence behind the role of genetics in drug response
    Beyond the hype: the evidence behind the role of genetics in drug...
    Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
    Speaker: Matt Nelson, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    5
    FEB 22, 2017 | 6:00 AM
    Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
    Mate-pair next generation sequencing as a powerful clinical tool...
    Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
    FEB 21, 2017 | 11:00 AM
    Genome Engineering to Introduce a Fluorescent Reporter into Human Pluripotent Stem Cells to Study Cardiac Disease
    Genome Engineering to Introduce a Fluorescent Reporter into Human...
    The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
    Speaker: Lise Munsie, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
    FEB 20, 2017 | 8:00 AM
    Tips, hints and trouble shooting: optimization of your recombinant protein preparation workflow
    Tips, hints and trouble shooting: optimization of your recombinant...
    First established in the 1880’s, cell culture is the process by which cells are grown in a laboratory under controlled environment. The culturing of different kinds of cells supports sc...
    Speaker: Quangvu Nguyen
    Presented at: Protein Research Live
    5
     
     
  • FEB 20, 2017 | 8:00 AM
    Presenting a complete workflow - from start to finish!
    Presenting a complete workflow - from start to finish!
    The CRISPR-Cas9 system is being widely used for genome engineering in many different biological applications. It was originally adapted from the bacterial Type II CRISPR system and uses a Cas...
    Speaker: Emily Anderson, Ph.D.
    Presented at: Protein Research Live
    4
    FEB 09, 2017 | 3:00 PM
    Education/Training/CPD from the Chinese perspective
    Education/Training/CPD from the Chinese perspective
    DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
    Speaker: Wanyong (William) Pang, BVM, MS, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 09, 2017 | 6:00 AM
    Continuous Professional Development (CPD) in Laboratory Animal Science, a continuous improvement in animal welfare and science
    Continuous Professional Development (CPD) in Laboratory Animal...
    DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThere is no professional area in which CPD is more necessary than in the field of laboratory animals. The continuous advancement of scien...
    Speaker: Patri Vergara, DVM, PhD, DipECLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
    FEB 08, 2017 | 1:30 PM
    Safety and pharmacokinetic profiles of different buprenorphine SR doses in a rabbit model
    Safety and pharmacokinetic profiles of different buprenorphine...
    DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
    Speaker: Andrea Zanetti, DVM, PhD, SRS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
    FEB 08, 2017 | 1:30 PM
    Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
    Characterization of Niemann Pick Type C mutant mice using automated...
    DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
    Speaker: Sangeetha Iyer, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    1
     
     
  • FEB 08, 2017 | 10:30 AM
    Biosecurity, Reproductive and Social Management of Cat Research Colonies
    Biosecurity, Reproductive and Social Management of Cat Research...
    DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
    Speaker: James Kehler VMD, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    JAN 27, 2017 | 4:00 AM
    WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity Through Time and Space by Mass Cytometry
    WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity...
    DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
    Speaker: Bernd Bodenmiller, PhD , Randall Wetzel, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    16
    JAN 19, 2017 | 8:00 AM
    Webinar: Detecting meaningful mutations from liquid biopsies by Anchored Multiplex PCR
    Webinar: Detecting meaningful mutations from liquid biopsies by...
    DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
    Speaker: Josh Stahl , Jonathan Doose
    Sponsored By: ArcherDX, ArcherDX
    9
    JAN 17, 2017 | 8:00 AM
    Regulation of Bivalent Domains by Histone Modifications
    Regulation of Bivalent Domains by Histone Modifications
    Bivalent domains are thought to be controversial, yet crucial,  regulatory hubs in the differentiation of stem cells. Listen in as  Dr Philipp Voigt of the Wellcome Trust Centre for...
    Speaker: Philipp Voigt, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
    JAN 17, 2017 | 8:00 AM
    Single-Cell RNA-Seq and cell heterogeneity in the central nervous system
    Single-Cell RNA-Seq and cell heterogeneity in the central nervous...
    Recent advances in single-cell RNA sequencing are producing exciting new insights into cell diversity within different tissues and cancers. Listen in to hear  Dr Gonçalo Castelo-B...
    Speaker: Gonçalo Castelo-Branco, PhD , Amit Zeisel, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    5
     
     
  • JAN 17, 2017 | 8:00 AM
    Benefits and limitations of primary and secondary antibody conjugates
    Benefits and limitations of primary and secondary antibody conjugates
    Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
    Speaker: Javier Vancells, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
    JAN 17, 2017 | 8:00 AM
    An Introduction to In-Cell ELISA
    An Introduction to In-Cell ELISA
    In-Cell ELISA, is a well-accepted assay approach to perform quantitative immunocytochemistry of cultured cells using either a colormetric or fluorometric readout.  Join our In-Cell ELISA...
    Speaker: John Constable, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
    DEC 14, 2016 | 7:30 AM
    Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
    Advances in modeling human diseases using induced pluripotent...
    DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
    Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    7 1
    DEC 07, 2016 | 9:00 AM
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
    Speaker: Edgar Jacoby, Ph.D.
    Sponsored By: DiscoverX, DiscoverX
    4
    DEC 06, 2016 | 11:00 AM
    Expansion of Human Stem Cells in BioBLU Single-Use Vessels from Eppendorf
    Expansion of Human Stem Cells in BioBLU Single-Use Vessels from...
    DATE: December 6, 2016 TIME: 11:00am PT, 2:00pm ET Experimentation involving human stem cells (HSCs) is one of the fastest growing fields in research and development due, in large part, t...
    Speaker: Stacey Willard, PhD
    Sponsored By: Eppendorf, Eppendorf
    5 1
     
     
  • DEC 01, 2016 | 8:00 AM
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
    DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
    Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
    Sponsored By: Revvity
    3
    NOV 23, 2016 | 8:00 AM
    Studying Kinetics of Chromatin Assembly with SWATH-MS
    Studying Kinetics of Chromatin Assembly with SWATH-MS
    DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
    Speaker: Moritz Voelker-Albert , Andreas Schmidt
    Sponsored By: SCIEX OMICS, SCIEX OMICS
    24
    NOV 17, 2016 | 3:00 PM
    Molecular elucidation and engineering of stem cell fate decisions
    Molecular elucidation and engineering of stem cell fate decisions
    Stem cells play critical roles in the development of organisms, as well as in the maintenance and repair of organs and tissues throughout adulthood.  Advancing our understanding of mecha...
    Speaker: David Schaffer, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
    NOV 17, 2016 | 1:00 PM
    Initiatives to advance stem cell science and medicine at California's $3 billion stem cell agency
    Initiatives to advance stem cell science and medicine at California's...
    The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs.  With $3 billion in funding and 300 a...
    Speaker: Stephen Lin, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
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