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    Computational Biology

    Computational Biology: covers the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, ecological, behavioral, and social systems.

    Webinars

    • JUN 25, 2015 | 8:00 AM
      Large scale purification of RNA and RNA-based Nanoparticles by Preparative Ultracentrifugation
      Large scale purification of RNA and RNA-based Nanoparticles by...
      The emerging field of RNA nanotechnology has led to the utilization of the platform in the field of bionanotechnology as sensing platforms, diverse nanoparticle construction, in vivo computin...
      Speaker: Daniel Jasinski
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      7
      MAY 14, 2015 | 7:30 AM
      Keynote: Using genomics to understand human health and disease
      Keynote: Using genomics to understand human health and disease
      I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
      Speaker: Richard Myers, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      6
      MAY 13, 2015 | 1:30 PM
      Epigenomics of common, rare, and somatic variants underlying disease and cancer
      Epigenomics of common, rare, and somatic variants underlying disease...
      Perhaps the greatest surprise of genetic studies of human disease is that 90% of top-scoring disease-associated loci lie outside protein-coding regions. This has increased the urgency of mapp...
      Speaker: Manolis Kellis, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
      MAY 13, 2015 | 10:30 AM
      Population Scale Human Genome Analysis on the Cloud
      Population Scale Human Genome Analysis on the Cloud
      Advanced sequencing technologies have made population scale whole genome sequencing a possibility. However, current strategies for analysis of this data rely upon parallelization approaches t...
      Speaker: Peter White, PhD, James Hirmas
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
      MAY 13, 2015 | 10:30 AM
      Statistical methods for bulk and single-cell RNA-seq experiments
      Statistical methods for bulk and single-cell RNA-seq experiments
      I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
      Speaker: Christina Kendziorski, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4 1
      MAY 13, 2015 | 10:30 AM
      Transcriptome Assembly: Computational Challenges of Next-Generation Sequence Data
      Transcriptome Assembly: Computational Challenges of Next-Generation...
      Next-generation sequencing technology allows us to peer inside the cell in exquisite detail, revealing new insights into biology, evolution, and disease that would have been impossible to dis...
      Speaker: Steven Salzberg, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
      MAY 13, 2015 | 7:30 AM
      Keynote: Big Data in Health Care and Biomedical Research
      Keynote: Big Data in Health Care and Biomedical Research
      Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      0 1
      APR 30, 2015 | 8:00 AM
      Swimming in Transcriptomics: Using Next-Gen sequencing to study the evolution of neural circuitry and swimming behavior of sea slugs
      Swimming in Transcriptomics: Using Next-Gen sequencing to study...
      Sea slugs (Mollusca, Gastropoda, Nudipleura) provide unique opportunities for studying the evolution of behavior at the levels of single neurons, neural circuits, and their synaptic connectio...
      Speaker: Adriano Senatore, PhD, MSc, BSc
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Genomics, Beckman Coulter Genomics
      9
      MAR 19, 2015 | 3:00 PM
      Early Days of the NIH BRAIN initiative
      Early Days of the NIH BRAIN initiative
      The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
      Speaker: Walter Koroshetz, MD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 19, 2015 | 10:30 AM
      Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor Systems: 3 Decades of Progress
      Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor...
      Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
      Speaker: Dean Wong, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      12
      MAR 18, 2015 | 3:00 PM
      The Human Connectome Project
      The Human Connectome Project
      Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
      Speaker: David Van Essen, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      FEB 05, 2015 | 9:00 AM
      C.E. CREDITS
      Keynote: Advances in Perioperative Care -Promoting good animal welfare and good science
      Keynote: Advances in Perioperative Care -Promoting good animal...
      Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
      Speaker: Paul Flecknell, MA, VetMB, PhD, DLAS, DECVAA, DECLAM, (Hon)DACLAM, (Hon) FRCVS, Dr.hc
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      6
      OCT 30, 2014 | 3:00 PM
      Probing cancer metabolism using isotope tracers to identify therapeutic targets
      Probing cancer metabolism using isotope tracers to identify therapeutic...
      Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
      Speaker: Christian Metallo, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 1:30 PM
      Structural Pathways of Cancer
      Structural Pathways of Cancer
      Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
      Speaker: Ruth Nussinov, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 12:00 PM
      Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
      Breast-Predict: Leveraging the Power of Systems Medicine Towards...
      Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
      Speaker: William M. Gallagher, BSc PhD CBiol MSB
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      SEP 24, 2014 | 2:00 PM
      Design of protein structures, functions and assemblies
      Design of protein structures, functions and assemblies
      I will describe recent advances in computational protein design which allow the generation of new protein structures and functions. I will describe the use of these methods to design ultra-s...
      Speaker: David Baker, PhD
      Presented at: Advances in Drug Discovery and Development
      32
      SEP 24, 2014 | 2:00 PM
      Targeting Lysine Acetylation in Cancer
      Targeting Lysine Acetylation in Cancer
      Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
      Speaker: Jay Bradner, MD
      Presented at: Advances in Drug Discovery and Development
      18
      SEP 24, 2014 | 11:00 AM
      Drug Repositioning in the Era of Personalized Medicine
      Drug Repositioning in the Era of Personalized Medicine
      This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
      Speaker: Craig Webb, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      32
      SEP 24, 2014 | 5:00 AM
      Algorithmic Drug Design (Prerecorded)
      Algorithmic Drug Design (Prerecorded)
      Since leaving Pfizer to go back to academia in 2007, Andrew Hopkins (University of Dundee, UK) has been a leading researcher in the search for new informatics and computational methods to imp...
      Speaker: Andrew Hopkins, FRSC
      Presented at: Advances in Drug Discovery and Development
      28
      SEP 10, 2014 | 10:00 AM
      NGS Lessons in Translational Diagnostics
      NGS Lessons in Translational Diagnostics
      In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
      Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
      Sponsored By: Asuragen, Asuragen
      48
      AUG 20, 2014 | 2:15 PM
      Identifying transcriptional regulators of human embryonic development via expression variability
      Identifying transcriptional regulators of human embryonic development...
      Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 12:30 PM
      Integrative Systems Approaches to Network Modeling of Biological Processes
      Integrative Systems Approaches to Network Modeling of Biological...
      ...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      44
      AUG 20, 2014 | 7:00 AM
      Human Genome Analysis
      Human Genome Analysis
      The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
      Speaker: Mark B Gerstein, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      MAR 20, 2014 | 2:00 PM
      Disinhibition Drives Rapid Movement and Associative Motor Memory Formation in the Cerebellum
      Disinhibition Drives Rapid Movement and Associative Motor Memory...
      Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
    JUN 25, 2015 | 8:00 AM
    Large scale purification of RNA and RNA-based Nanoparticles by Preparative Ultracentrifugation
    Large scale purification of RNA and RNA-based Nanoparticles by...
    The emerging field of RNA nanotechnology has led to the utilization of the platform in the field of bionanotechnology as sensing platforms, diverse nanoparticle construction, in vivo computin...
    Speaker: Daniel Jasinski
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    7
    MAY 14, 2015 | 7:30 AM
    Keynote: Using genomics to understand human health and disease
    Keynote: Using genomics to understand human health and disease
    I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
    Speaker: Richard Myers, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    6
    MAY 13, 2015 | 1:30 PM
    Epigenomics of common, rare, and somatic variants underlying disease and cancer
    Epigenomics of common, rare, and somatic variants underlying disease...
    Perhaps the greatest surprise of genetic studies of human disease is that 90% of top-scoring disease-associated loci lie outside protein-coding regions. This has increased the urgency of mapp...
    Speaker: Manolis Kellis, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
    MAY 13, 2015 | 10:30 AM
    Population Scale Human Genome Analysis on the Cloud
    Population Scale Human Genome Analysis on the Cloud
    Advanced sequencing technologies have made population scale whole genome sequencing a possibility. However, current strategies for analysis of this data rely upon parallelization approaches t...
    Speaker: Peter White, PhD, James Hirmas
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
    MAY 13, 2015 | 10:30 AM
    Statistical methods for bulk and single-cell RNA-seq experiments
    Statistical methods for bulk and single-cell RNA-seq experiments
    I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
    Speaker: Christina Kendziorski, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4 1
     
     
  • MAY 13, 2015 | 10:30 AM
    Transcriptome Assembly: Computational Challenges of Next-Generation Sequence Data
    Transcriptome Assembly: Computational Challenges of Next-Generation...
    Next-generation sequencing technology allows us to peer inside the cell in exquisite detail, revealing new insights into biology, evolution, and disease that would have been impossible to dis...
    Speaker: Steven Salzberg, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
    MAY 13, 2015 | 7:30 AM
    Keynote: Big Data in Health Care and Biomedical Research
    Keynote: Big Data in Health Care and Biomedical Research
    Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    0 1
    APR 30, 2015 | 8:00 AM
    Swimming in Transcriptomics: Using Next-Gen sequencing to study the evolution of neural circuitry and swimming behavior of sea slugs
    Swimming in Transcriptomics: Using Next-Gen sequencing to study...
    Sea slugs (Mollusca, Gastropoda, Nudipleura) provide unique opportunities for studying the evolution of behavior at the levels of single neurons, neural circuits, and their synaptic connectio...
    Speaker: Adriano Senatore, PhD, MSc, BSc
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Genomics, Beckman Coulter Genomics
    9
    MAR 19, 2015 | 3:00 PM
    Early Days of the NIH BRAIN initiative
    Early Days of the NIH BRAIN initiative
    The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
    Speaker: Walter Koroshetz, MD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 19, 2015 | 10:30 AM
    Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor Systems: 3 Decades of Progress
    Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor...
    Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
    Speaker: Dean Wong, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    12
     
     
  • MAR 18, 2015 | 3:00 PM
    The Human Connectome Project
    The Human Connectome Project
    Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
    Speaker: David Van Essen, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    FEB 05, 2015 | 9:00 AM
    C.E. CREDITS
    Keynote: Advances in Perioperative Care -Promoting good animal welfare and good science
    Keynote: Advances in Perioperative Care -Promoting good animal...
    Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
    Speaker: Paul Flecknell, MA, VetMB, PhD, DLAS, DECVAA, DECLAM, (Hon)DACLAM, (Hon) FRCVS, Dr.hc
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    6
    OCT 30, 2014 | 3:00 PM
    Probing cancer metabolism using isotope tracers to identify therapeutic targets
    Probing cancer metabolism using isotope tracers to identify therapeutic...
    Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
    Speaker: Christian Metallo, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 1:30 PM
    Structural Pathways of Cancer
    Structural Pathways of Cancer
    Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
    Speaker: Ruth Nussinov, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 12:00 PM
    Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
    Breast-Predict: Leveraging the Power of Systems Medicine Towards...
    Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
    Speaker: William M. Gallagher, BSc PhD CBiol MSB
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
     
     
  • SEP 24, 2014 | 2:00 PM
    Design of protein structures, functions and assemblies
    Design of protein structures, functions and assemblies
    I will describe recent advances in computational protein design which allow the generation of new protein structures and functions. I will describe the use of these methods to design ultra-s...
    Speaker: David Baker, PhD
    Presented at: Advances in Drug Discovery and Development
    32
    SEP 24, 2014 | 2:00 PM
    Targeting Lysine Acetylation in Cancer
    Targeting Lysine Acetylation in Cancer
    Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
    Speaker: Jay Bradner, MD
    Presented at: Advances in Drug Discovery and Development
    18
    SEP 24, 2014 | 11:00 AM
    Drug Repositioning in the Era of Personalized Medicine
    Drug Repositioning in the Era of Personalized Medicine
    This presentation will focus on NuMediis general approach towards the discovery of new therapeutic uses for existing drugs. While the business models for repurposing marketed drugs versus rep...
    Speaker: Craig Webb, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    32
    SEP 24, 2014 | 5:00 AM
    Algorithmic Drug Design (Prerecorded)
    Algorithmic Drug Design (Prerecorded)
    Since leaving Pfizer to go back to academia in 2007, Andrew Hopkins (University of Dundee, UK) has been a leading researcher in the search for new informatics and computational methods to imp...
    Speaker: Andrew Hopkins, FRSC
    Presented at: Advances in Drug Discovery and Development
    28
    SEP 10, 2014 | 10:00 AM
    NGS Lessons in Translational Diagnostics
    NGS Lessons in Translational Diagnostics
    In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
    Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
    Sponsored By: Asuragen, Asuragen
    48
     
     
  • AUG 20, 2014 | 2:15 PM
    Identifying transcriptional regulators of human embryonic development via expression variability
    Identifying transcriptional regulators of human embryonic development...
    Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    AUG 20, 2014 | 12:30 PM
    Integrative Systems Approaches to Network Modeling of Biological Processes
    Integrative Systems Approaches to Network Modeling of Biological...
    ...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    44
    AUG 20, 2014 | 7:00 AM
    Human Genome Analysis
    Human Genome Analysis
    The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
    Speaker: Mark B Gerstein, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    MAR 20, 2014 | 2:00 PM
    Disinhibition Drives Rapid Movement and Associative Motor Memory Formation in the Cerebellum
    Disinhibition Drives Rapid Movement and Associative Motor Memory...
    Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
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