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CRISPR-Cas9
CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.
MAY 09, 2019 | 10:30 AM
Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
MAY 09, 2019 | 9:00 AM
The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
MAY 09, 2019 | 9:00 AM
Release of the first human genome assembly was a landmark achievement, and after nearly two decades of improvements, the current human reference genome (GRCh38) is the most accurate and compl...
MAY 09, 2019 | 7:30 AM
C.E. CREDITS
Recent technological advances as well as longitudinal monitoring not only have the potential to improve the treatment of disease (Precision Medicine) but also empower people to stay healthy (...
MAY 09, 2019 | 6:00 AM
Variant interpretation presents a bottleneck for many labs, posing a challenge to the broader adoption of precision medicine. The ACMG/AMP variant classification framework has provided a foun...
MAY 08, 2019 | 1:30 PM
Recent improvements in sequencing chemistry and instrument performance combine to create a new PacBio data type of highly accurate (HiFi), long insert reads. Increased read length and improve...
MAY 08, 2019 | 12:00 PM
Next-generation transcriptome and miRNome sequencing are routinely performed on traditional cell or tissue samples, as well as more difficult samples such as FFPE samples and biofluids. Regar...
