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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • FEB 05, 2014 | 5:00 PM
      Designing a health - monitoring programme for laboratory mice
      Designing a health - monitoring programme for laboratory mice
      Monitoring the health of laboratory rodents is an important tool for improving the quality of animals used in research. However not all animal facilities have the same requirements, and an ex...
      Speaker: Jenny Kingham, BVSc, MACVSc ( Lab Anim)
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 4:00 PM
      Cryopreservation: a cold solution
      Cryopreservation: a cold solution
      The popularity reached by the genetic manipulation of laboratory animals to create new models for studying human diseases, produced in turn, that the techniques for assisted reproduction cons...
      Speaker: Jorge Sztein, DVM, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 2:00 PM
      Rodent Health Surveillance:  Innovation driving changes
      Rodent Health Surveillance: Innovation driving changes
      Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
      Speaker: Charles Clifford, DVM, PhD, DACVP
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      4
      FEB 05, 2014 | 2:00 PM
      Guidelines for Inanimate Surgical Training and Competency Assessment; Improvement of Animal Welfare and Decreasing Confounding Factors
      Guidelines for Inanimate Surgical Training and Competency Assessment;...
      With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 1:00 PM
      Gross and Histopathologic Pathology of Rhesus Macaques
      Gross and Histopathologic Pathology of Rhesus Macaques
      This seminar will cover spontaneous diseases of Rhesus Macaques utilizing a systemic approach. It will consist of gross and histopathologic images of common pathologic conditions highlighting...
      Speaker: Olga Gonzalez, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 11:00 AM
      Biology and Laboratory Management of Rabbits (Oryctolagus cuniculus)
      Biology and Laboratory Management of Rabbits (Oryctolagus cuniculus)
      Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
      Speaker: Marilyn Arce Rivera, DVM, MLAS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 05, 2014 | 10:00 AM
      Biology and Laboratory Management of Rhesus Macaques (Macaca mulatta)
      Biology and Laboratory Management of Rhesus Macaques (Macaca mulatta)
      Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
      Speaker: Marilyn Arce Rivera, DVM, MLAS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 05, 2014 | 9:00 AM
      What Germs? Hiring and Training Gnotobiotic Technicians
      What Germs? Hiring and Training Gnotobiotic Technicians
      The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
      Speaker: Michelle Hull, MS RLATg
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      3
      OCT 17, 2013 | 12:00 PM
      C.E. CREDITS
      Embracing the Complexity of Cancer: Seeing the Forest and the Trees
      Embracing the Complexity of Cancer: Seeing the Forest and the...
      Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      34
      OCT 16, 2013 | 2:00 PM
      C.E. CREDITS
      Novel therapies for ALK mutated cancers
      Novel therapies for ALK mutated cancers
      Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
      Speaker: Roberto Chiarle, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
      Resistance to AR Signaling Inhibitors in Castration Resistant...
      While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
      Speaker: Elahe A Mostaghel, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 11:00 AM
      C.E. CREDITS
      Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
      Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
      Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
      Speaker: Ross L. Cagan, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      78
      OCT 16, 2013 | 9:00 AM
      C.E. CREDITS
      Keynote: Breast Cancer Genomics and Genetics
      Keynote: Breast Cancer Genomics and Genetics
      It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
      Speaker: Charles M. Perou, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      132
      OCT 16, 2013 | 7:00 AM
      C.E. CREDITS
      Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
      Prognostic, predictive, and surrogate biomarkers in men with castration...
      With the rapid rise in the number of therapeutic options for men with castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision-making, emphasizing the nee...
      Speaker: Andrew Armstrong, MD ScM FACP
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      96
      AUG 22, 2013 | 2:00 PM
      The Road to Genomic Medicine is Paved with Data and Information
      The Road to Genomic Medicine is Paved with Data and Information
      Since the introduction of second-generation DNS sequencing technologies in 2007, the cost of genome sequencing has been consistently by 33% per quarter, with the $1000 genome arriving in 2012...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      110
      AUG 22, 2013 | 1:00 PM
      Embracing the Complexity of Cancer: Seeing the Forest and the Trees
      Embracing the Complexity of Cancer: Seeing the Forest and the...
      Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2013
      92
      AUG 22, 2013 | 9:00 AM
      C.E. CREDITS
      Return of Genome Sequencing Results to Physicians and Patients
      Return of Genome Sequencing Results to Physicians and Patients
      There has been considerable debate in the scientific and clinical communities regarding the return of results from genome sequencing to physicians and patients. Questions surrounding which he...
      Speaker: Cinnamon S Bloss, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      56
      AUG 21, 2013 | 2:00 PM
      Claritas Genomics: The Future of Pediatric Diagnostics is Now
      Claritas Genomics: The Future of Pediatric Diagnostics is Now
      Increasingly genome sequence knowledge is unraveling the complexity of rare Mendelian disorders offering hope for our children's medical care through better disease diagnosis and ultimately p...
      Speaker: Patrice Milos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      96
      AUG 21, 2013 | 2:00 PM
      C.E. CREDITS
      The role of protective genes in the exceptional longevity of humans
      The role of protective genes in the exceptional longevity of humans
      Aging is the major risk for diseases such as cancer, AD, type 2 Diabetes mellitus and cardiovascular disease. We hypothesize that a progress in preventing these diseases will occur only if we...
      Speaker: Nir Barzilai, MD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      38
      AUG 21, 2013 | 10:00 AM
      C.E. CREDITS
      Azole resistance in Aspergillus fumigatus - clinical isolate screening, culture selection, and genetics
      Azole resistance in Aspergillus fumigatus - clinical isolate screening,...
      In the United States, invasive aspergillosis (IA), an invasive fungal infection of the upper respiratory tract of immune compromised patients, is usually caused by Aspergilus fumigatus, while...
      Speaker: William C Nierman, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      67
      AUG 21, 2013 | 8:00 AM
      Post Genome-Wide Association Studies
      Post Genome-Wide Association Studies
      In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      105
    FEB 05, 2014 | 5:00 PM
    Designing a health - monitoring programme for laboratory mice
    Designing a health - monitoring programme for laboratory mice
    Monitoring the health of laboratory rodents is an important tool for improving the quality of animals used in research. However not all animal facilities have the same requirements, and an ex...
    Speaker: Jenny Kingham, BVSc, MACVSc ( Lab Anim)
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 4:00 PM
    Cryopreservation: a cold solution
    Cryopreservation: a cold solution
    The popularity reached by the genetic manipulation of laboratory animals to create new models for studying human diseases, produced in turn, that the techniques for assisted reproduction cons...
    Speaker: Jorge Sztein, DVM, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 2:00 PM
    Rodent Health Surveillance:  Innovation driving changes
    Rodent Health Surveillance: Innovation driving changes
    Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
    Speaker: Charles Clifford, DVM, PhD, DACVP
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    4
    FEB 05, 2014 | 2:00 PM
    Guidelines for Inanimate Surgical Training and Competency Assessment; Improvement of Animal Welfare and Decreasing Confounding Factors
    Guidelines for Inanimate Surgical Training and Competency Assessment;...
    With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 1:00 PM
    Gross and Histopathologic Pathology of Rhesus Macaques
    Gross and Histopathologic Pathology of Rhesus Macaques
    This seminar will cover spontaneous diseases of Rhesus Macaques utilizing a systemic approach. It will consist of gross and histopathologic images of common pathologic conditions highlighting...
    Speaker: Olga Gonzalez, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
     
     
  • FEB 05, 2014 | 11:00 AM
    Biology and Laboratory Management of Rabbits (Oryctolagus cuniculus)
    Biology and Laboratory Management of Rabbits (Oryctolagus cuniculus)
    Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
    Speaker: Marilyn Arce Rivera, DVM, MLAS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 05, 2014 | 10:00 AM
    Biology and Laboratory Management of Rhesus Macaques (Macaca mulatta)
    Biology and Laboratory Management of Rhesus Macaques (Macaca mulatta)
    Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
    Speaker: Marilyn Arce Rivera, DVM, MLAS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 05, 2014 | 9:00 AM
    What Germs? Hiring and Training Gnotobiotic Technicians
    What Germs? Hiring and Training Gnotobiotic Technicians
    The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
    Speaker: Michelle Hull, MS RLATg
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    3
    OCT 17, 2013 | 12:00 PM
    C.E. CREDITS
    Embracing the Complexity of Cancer: Seeing the Forest and the Trees
    Embracing the Complexity of Cancer: Seeing the Forest and the...
    Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    34
    OCT 16, 2013 | 2:00 PM
    C.E. CREDITS
    Novel therapies for ALK mutated cancers
    Novel therapies for ALK mutated cancers
    Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
    Speaker: Roberto Chiarle, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
     
     
  • OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
    Resistance to AR Signaling Inhibitors in Castration Resistant...
    While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
    Speaker: Elahe A Mostaghel, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    OCT 16, 2013 | 11:00 AM
    C.E. CREDITS
    Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
    Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
    Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
    Speaker: Ross L. Cagan, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    78
    OCT 16, 2013 | 9:00 AM
    C.E. CREDITS
    Keynote: Breast Cancer Genomics and Genetics
    Keynote: Breast Cancer Genomics and Genetics
    It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
    Speaker: Charles M. Perou, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    132
    OCT 16, 2013 | 7:00 AM
    C.E. CREDITS
    Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
    Prognostic, predictive, and surrogate biomarkers in men with castration...
    With the rapid rise in the number of therapeutic options for men with castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision-making, emphasizing the nee...
    Speaker: Andrew Armstrong, MD ScM FACP
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    96
    AUG 22, 2013 | 2:00 PM
    The Road to Genomic Medicine is Paved with Data and Information
    The Road to Genomic Medicine is Paved with Data and Information
    Since the introduction of second-generation DNS sequencing technologies in 2007, the cost of genome sequencing has been consistently by 33% per quarter, with the $1000 genome arriving in 2012...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    110
     
     
  • AUG 22, 2013 | 1:00 PM
    Embracing the Complexity of Cancer: Seeing the Forest and the Trees
    Embracing the Complexity of Cancer: Seeing the Forest and the...
    Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2013
    92
    AUG 22, 2013 | 9:00 AM
    C.E. CREDITS
    Return of Genome Sequencing Results to Physicians and Patients
    Return of Genome Sequencing Results to Physicians and Patients
    There has been considerable debate in the scientific and clinical communities regarding the return of results from genome sequencing to physicians and patients. Questions surrounding which he...
    Speaker: Cinnamon S Bloss, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    56
    AUG 21, 2013 | 2:00 PM
    Claritas Genomics: The Future of Pediatric Diagnostics is Now
    Claritas Genomics: The Future of Pediatric Diagnostics is Now
    Increasingly genome sequence knowledge is unraveling the complexity of rare Mendelian disorders offering hope for our children's medical care through better disease diagnosis and ultimately p...
    Speaker: Patrice Milos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    96
    AUG 21, 2013 | 2:00 PM
    C.E. CREDITS
    The role of protective genes in the exceptional longevity of humans
    The role of protective genes in the exceptional longevity of humans
    Aging is the major risk for diseases such as cancer, AD, type 2 Diabetes mellitus and cardiovascular disease. We hypothesize that a progress in preventing these diseases will occur only if we...
    Speaker: Nir Barzilai, MD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    38
    AUG 21, 2013 | 10:00 AM
    C.E. CREDITS
    Azole resistance in Aspergillus fumigatus - clinical isolate screening, culture selection, and genetics
    Azole resistance in Aspergillus fumigatus - clinical isolate screening,...
    In the United States, invasive aspergillosis (IA), an invasive fungal infection of the upper respiratory tract of immune compromised patients, is usually caused by Aspergilus fumigatus, while...
    Speaker: William C Nierman, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    67
     
     
  • AUG 21, 2013 | 8:00 AM
    Post Genome-Wide Association Studies
    Post Genome-Wide Association Studies
    In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    105
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