Immunity: is the balanced state of multicellular organisms having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases.
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
Cancer biologists, pharmacologists and immunologists have historically communicated little with each other due to different traditions in training and a lack of integrated perspectives on can...
Review the similarities and differences between apoptosis and necroptosis, with an introduction to new tools developed to activate effectors of necroptosis....
DATE: November 15, 2016
TIME: 9:00 AM PT, 12:00 PM ET
The virulent intracellular pathogen Francisella tularensis subsp. tularensis (Ftt) causes an acute, lethal diseas...
DATE: November 10, 2016
TIME: 10am PT, 1pm ET
How do you effectively detect heterogeneity in single cells?
Bulk analysis often leads to conclusions that assume average...
Bulk analysis often leads to conclusions that assume averages reflect the dominant biological mechanism operating within an entire population. To fully understand how cellular heterogeneity c...
DATE: November 10, 2016
TIME: 9:00am PT, Noon ET
The CellSimple™ Cell Analyzer enables quick and easy research assays, including functional cell-based assays, cell-model...
New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
The immune system possesses significant cytotoxic potential. Stimulating natural immunity through vaccination has shown promising effects in some cancers; however, a number of barriers limit...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
DATE: October 4, 2016
TIME: 8:00am PT, 11:00am ET
Extracting robust expression data from clinical samples represents a unique opportunity to find actionable biomarkers. But it...
DATE: September 28, 2016TIME: 9:00am Pacific time, 12:00pm Eastern timeNK cells play critical roles in immune defense and reproduction but remain the most poorly under...
The research community has begun correlating the makeup of individual microbiomes with disorders and diseases such as obesity, atherosclerosis and cancer. To accomplish this, researchers must...
The human body is populated with trillions of microorganisms, collectively termed the human microbiome, that play vital roles in health including nutrition and metabolism, immune development,...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and va...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Mesenchymal stromal cell (MSC) therapy is a promising option to support endogenous regeneration and immunomodulation. However, the clinical results are contradictory. We think that the recent...
In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
DATE: July 20thTIME: 8AM PT, 11AM ET, 5PM CESTTherapies like ipilimumab and nivolumab have shown the potential for approaches that direct the patient’s own immune system aga...
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
Cancer biologists, pharmacologists and immunologists have historically communicated little with each other due to different traditions in training and a lack of integrated perspectives on can...
Review the similarities and differences between apoptosis and necroptosis, with an introduction to new tools developed to activate effectors of necroptosis....
DATE: November 15, 2016
TIME: 9:00 AM PT, 12:00 PM ET
The virulent intracellular pathogen Francisella tularensis subsp. tularensis (Ftt) causes an acute, lethal diseas...
DATE: November 10, 2016
TIME: 10am PT, 1pm ET
How do you effectively detect heterogeneity in single cells?
Bulk analysis often leads to conclusions that assume average...
Bulk analysis often leads to conclusions that assume averages reflect the dominant biological mechanism operating within an entire population. To fully understand how cellular heterogeneity c...
DATE: November 10, 2016
TIME: 9:00am PT, Noon ET
The CellSimple™ Cell Analyzer enables quick and easy research assays, including functional cell-based assays, cell-model...
New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
The immune system possesses significant cytotoxic potential. Stimulating natural immunity through vaccination has shown promising effects in some cancers; however, a number of barriers limit...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
DATE: October 4, 2016
TIME: 8:00am PT, 11:00am ET
Extracting robust expression data from clinical samples represents a unique opportunity to find actionable biomarkers. But it...
DATE: September 28, 2016TIME: 9:00am Pacific time, 12:00pm Eastern timeNK cells play critical roles in immune defense and reproduction but remain the most poorly under...
The research community has begun correlating the makeup of individual microbiomes with disorders and diseases such as obesity, atherosclerosis and cancer. To accomplish this, researchers must...
The human body is populated with trillions of microorganisms, collectively termed the human microbiome, that play vital roles in health including nutrition and metabolism, immune development,...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and va...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Mesenchymal stromal cell (MSC) therapy is a promising option to support endogenous regeneration and immunomodulation. However, the clinical results are contradictory. We think that the recent...
In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
DATE: July 20thTIME: 8AM PT, 11AM ET, 5PM CESTTherapies like ipilimumab and nivolumab have shown the potential for approaches that direct the patient’s own immune system aga...
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