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    Large Molecule

    Large Molecule or macromolecule is a very large molecule, such as protein, commonly created by the polymerization of smaller subunits. They are typically composed of thousands of atoms or more. The most common macromolecules in biochemistry are biopolymers and large non-polymeric molecule.

    Webinars

    • MAR 05, 2019 | 9:00 AM
      Strategies to normalize miRNA expression in serum and plasma.
      Strategies to normalize miRNA expression in serum and plasma.
      DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      7
      FEB 14, 2019 | 1:30 PM
      Organs On a Chip:  A Revolution in Drug Development?
      Organs On a Chip: A Revolution in Drug Development?
      Pharmaceutical research and development efforts are often both inefficient and suffer from a high attrition rate of drug candidates within the clinical phase of development.  Most drug t...
      Speaker: Gorm Yoder, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 2
      DEC 06, 2018 | 7:00 AM
      Image-based screening for precision medicine and immunotherapy
      Image-based screening for precision medicine and immunotherapy
      DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
      Speaker: Dr. Gregory Vladimer
      Sponsored By: Revvity
      6
      NOV 08, 2018 | 5:00 PM
      NMR in standardizing biomarkers for personalized medicine: Where do biobanks come in?  (For research use only)
      NMR in standardizing biomarkers for personalized medicine: Where...
      DATE:  November 9, 2018 TIME:   09:00am CST, 10:00am JST, 12:00pm AEDT Perso and precision medicine are rapidly growing areas that require good data to categoriz...
      Speaker: Matthias Nauck, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      3
      OCT 11, 2018 | 1:30 PM
      Breast Cancer as a Global Disease: Are We Up to The Challenge?
      Breast Cancer as a Global Disease: Are We Up to The Challenge?
      As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
      Speaker: Benjamin Anderson, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      3
      OCT 11, 2018 | 12:00 PM
      Lung Cancer Evolution and Immune Escape
      Lung Cancer Evolution and Immune Escape
      Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
      Speaker: Nicholas McGranahan, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      AUG 30, 2018 | 8:00 AM
      Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
      Early disease detection performing NMR - Understanding how a better...
      DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
      Speaker: Elaine Holmes , Claudio Luchinat
      Sponsored By: Bruker Microbiology & Diagnostics
      6 2
      AUG 30, 2018 | 1:00 AM
      Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
      Early disease detection performing NMR - Understanding how a better...
      DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
      Speaker: Elaine Holmes , Claudio Luchinat
      Sponsored By: Bruker Microbiology & Diagnostics
      5 2
      JUN 29, 2018 | 8:00 AM
      Quantitation and profiling metabolomics and translation to clinical analysis
      Quantitation and profiling metabolomics and translation to clinical...
      DATE: June 29, 2018TIME: 8:00AM PDTMeasurement of these metabolites represents the digital readout of health.  A key aspect of metabolomics is the utilization of high resolu...
      Speaker: Timothy Garrett, PhD
      Sponsored By: Agilent
      7
      JUN 28, 2018 | 9:00 AM
      Step up your biologics stability screening with Hunky
      Step up your biologics stability screening with Hunky
      DATE: June 28, 2018TIME: 9:00AM PDTStep up your biologics stability screening with HunkyMany methods for studying protein stability and aggregation are qualitative, which can c...
      Speaker: Lisa Adamiak, PhD
      Sponsored By: Unchained Labs
      4
      MAY 30, 2018 | 6:00 AM
      Phenotypic Profiling for Improving Drug Discovery Productivity
      Phenotypic Profiling for Improving Drug Discovery Productivity
      The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
      Speaker: Ellen Berg, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2 1
      MAY 16, 2018 | 8:00 PM
      ExpiCHO High-Efficiency Protein Expression System: Ultra-high Titers Comparable to Stable Transfection Systems Achieved in Two Weeks (Presented in Chinese)
      ExpiCHO High-Efficiency Protein Expression System: Ultra-high...
      ExpiCHO是一种高效的瞬时表达系统,可以在2周内获得与稳定细胞株相当的表达量。 CHO细胞长期以来一直在工业界广泛使用,获得CHO表达蛋白必须构建稳定的细胞株,这一过程不仅耗时耗力,而且需要经验丰富的研发人员。在药物开发阶段需要在较短时间获得大量蛋白,往往只能采用293细胞的瞬转表达系统,但该系统产量低,表达蛋白与CHO系统存在质量差异。ExpiCHO作为高效的瞬时表达系统能...
      Speaker: Yuedan Kong
      Presented at: Gibco ExpressionWorld 2018
      7
      APR 30, 2018 | 8:00 AM
      Ion Mobility/Mass Spectrometry for Metabolomics and Clinical Research Analysis
      Ion Mobility/Mass Spectrometry for Metabolomics and Clinical Research...
      Ion mobility/mass spectrometry has tremendous potential for metabolomics, lipidomics, and clinical analysis. Ion mobility can resolve compounds unresolved by LC/MS/MS, provide additional stru...
      Speaker: Richard Yost, PhD
      Sponsored By: Agilent
      6
      MAR 28, 2018 | 10:30 AM
      Factors That Influence Label Accuracy - Who's to Blame?
      Factors That Influence Label Accuracy - Who's to Blame?
      DATE: March 28, 2018TIME: 10:30AM PDTAs consumers in modern society, we have become accustomed to the purchase of foods and drugs that are safe and accurately labeled. This is a result...
      Speaker: Catharine Layton
      Presented at: Cannabis Sciences Virtual Event Series 2018
      4
    MAR 05, 2019 | 9:00 AM
    Strategies to normalize miRNA expression in serum and plasma.
    Strategies to normalize miRNA expression in serum and plasma.
    DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    7
    FEB 14, 2019 | 1:30 PM
    Organs On a Chip:  A Revolution in Drug Development?
    Organs On a Chip: A Revolution in Drug Development?
    Pharmaceutical research and development efforts are often both inefficient and suffer from a high attrition rate of drug candidates within the clinical phase of development.  Most drug t...
    Speaker: Gorm Yoder, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 2
    DEC 06, 2018 | 7:00 AM
    Image-based screening for precision medicine and immunotherapy
    Image-based screening for precision medicine and immunotherapy
    DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
    Speaker: Dr. Gregory Vladimer
    Sponsored By: Revvity
    6
    NOV 08, 2018 | 5:00 PM
    NMR in standardizing biomarkers for personalized medicine: Where do biobanks come in?  (For research use only)
    NMR in standardizing biomarkers for personalized medicine: Where...
    DATE:  November 9, 2018 TIME:   09:00am CST, 10:00am JST, 12:00pm AEDT Perso and precision medicine are rapidly growing areas that require good data to categoriz...
    Speaker: Matthias Nauck, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    3
    OCT 11, 2018 | 1:30 PM
    Breast Cancer as a Global Disease: Are We Up to The Challenge?
    Breast Cancer as a Global Disease: Are We Up to The Challenge?
    As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
    Speaker: Benjamin Anderson, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    3
     
     
  • OCT 11, 2018 | 12:00 PM
    Lung Cancer Evolution and Immune Escape
    Lung Cancer Evolution and Immune Escape
    Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
    Speaker: Nicholas McGranahan, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
     
     
  • OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    AUG 30, 2018 | 8:00 AM
    Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
    Early disease detection performing NMR - Understanding how a better...
    DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
    Speaker: Elaine Holmes , Claudio Luchinat
    Sponsored By: Bruker Microbiology & Diagnostics
    6 2
    AUG 30, 2018 | 1:00 AM
    Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
    Early disease detection performing NMR - Understanding how a better...
    DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
    Speaker: Elaine Holmes , Claudio Luchinat
    Sponsored By: Bruker Microbiology & Diagnostics
    5 2
    JUN 29, 2018 | 8:00 AM
    Quantitation and profiling metabolomics and translation to clinical analysis
    Quantitation and profiling metabolomics and translation to clinical...
    DATE: June 29, 2018TIME: 8:00AM PDTMeasurement of these metabolites represents the digital readout of health.  A key aspect of metabolomics is the utilization of high resolu...
    Speaker: Timothy Garrett, PhD
    Sponsored By: Agilent
    7
    JUN 28, 2018 | 9:00 AM
    Step up your biologics stability screening with Hunky
    Step up your biologics stability screening with Hunky
    DATE: June 28, 2018TIME: 9:00AM PDTStep up your biologics stability screening with HunkyMany methods for studying protein stability and aggregation are qualitative, which can c...
    Speaker: Lisa Adamiak, PhD
    Sponsored By: Unchained Labs
    4
     
     
  • MAY 30, 2018 | 6:00 AM
    Phenotypic Profiling for Improving Drug Discovery Productivity
    Phenotypic Profiling for Improving Drug Discovery Productivity
    The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
    Speaker: Ellen Berg, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2 1
    MAY 16, 2018 | 8:00 PM
    ExpiCHO High-Efficiency Protein Expression System: Ultra-high Titers Comparable to Stable Transfection Systems Achieved in Two Weeks (Presented in Chinese)
    ExpiCHO High-Efficiency Protein Expression System: Ultra-high...
    ExpiCHO是一种高效的瞬时表达系统,可以在2周内获得与稳定细胞株相当的表达量。 CHO细胞长期以来一直在工业界广泛使用,获得CHO表达蛋白必须构建稳定的细胞株,这一过程不仅耗时耗力,而且需要经验丰富的研发人员。在药物开发阶段需要在较短时间获得大量蛋白,往往只能采用293细胞的瞬转表达系统,但该系统产量低,表达蛋白与CHO系统存在质量差异。ExpiCHO作为高效的瞬时表达系统能...
    Speaker: Yuedan Kong
    Presented at: Gibco ExpressionWorld 2018
    7
    APR 30, 2018 | 8:00 AM
    Ion Mobility/Mass Spectrometry for Metabolomics and Clinical Research Analysis
    Ion Mobility/Mass Spectrometry for Metabolomics and Clinical Research...
    Ion mobility/mass spectrometry has tremendous potential for metabolomics, lipidomics, and clinical analysis. Ion mobility can resolve compounds unresolved by LC/MS/MS, provide additional stru...
    Speaker: Richard Yost, PhD
    Sponsored By: Agilent
    6
    MAR 28, 2018 | 10:30 AM
    Factors That Influence Label Accuracy - Who's to Blame?
    Factors That Influence Label Accuracy - Who's to Blame?
    DATE: March 28, 2018TIME: 10:30AM PDTAs consumers in modern society, we have become accustomed to the purchase of foods and drugs that are safe and accurately labeled. This is a result...
    Speaker: Catharine Layton
    Presented at: Cannabis Sciences Virtual Event Series 2018
    4
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