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    Protein Engineering

    Protein Engineering: is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles.

    Webinars

    • MAY 30, 2018 | 6:00 AM
      Phenotypic Profiling for Improving Drug Discovery Productivity
      Phenotypic Profiling for Improving Drug Discovery Productivity
      The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
      Speaker: Ellen Berg, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2 1
      MAY 22, 2018 | 8:00 AM
      Drug development with nuclear receptor knockout and humanized rat models
      Drug development with nuclear receptor knockout and humanized...
      DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
      Speaker: Kevin Forbes, PhD , Andrew Brown, MS
      Sponsored By: Horizon Discovery
      5
      MAY 16, 2018 | 8:00 PM
      ExpiCHO High-Efficiency Protein Expression System: Ultra-high Titers Comparable to Stable Transfection Systems Achieved in Two Weeks (Presented in Chinese)
      ExpiCHO High-Efficiency Protein Expression System: Ultra-high...
      ExpiCHO是一种高效的瞬时表达系统,可以在2周内获得与稳定细胞株相当的表达量。 CHO细胞长期以来一直在工业界广泛使用,获得CHO表达蛋白必须构建稳定的细胞株,这一过程不仅耗时耗力,而且需要经验丰富的研发人员。在药物开发阶段需要在较短时间获得大量蛋白,往往只能采用293细胞的瞬转表达系统,但该系统产量低,表达蛋白与CHO系统存在质量差异。ExpiCHO作为高效的瞬时表达系统能...
      Speaker: Yuedan Kong
      Presented at: Gibco ExpressionWorld 2018
      7
      MAY 02, 2018 | 8:00 AM
      Five steps for publication-quality immunohistochemistry imaging
      Five steps for publication-quality immunohistochemistry imaging
      Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
      Speaker: Jason Kilgore
      Sponsored By: Thermo Fisher Scientific
      10
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      MAR 27, 2018 | 9:00 AM
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
      Speaker: Amanda Haas
      Sponsored By: Horizon Discovery
      23 15
      MAR 22, 2018 | 9:00 AM
      Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
      Differentiation sensitizes stem-like glioblastoma tumor-initiating...
      DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
      Speaker: Jasmine Hughes
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 4
      MAR 15, 2018 | 10:30 AM
      An Emerging Role of DNA Damage-Repair in Huntington's Disease
      An Emerging Role of DNA Damage-Repair in Huntington's Disease
      Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
      Speaker: Animesh Ray, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
      MAR 15, 2018 | 10:30 AM
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
      The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
      Speaker: Jill Weimer, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      MAR 14, 2018 | 6:00 AM
      Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery of Biologics for Alzheimer's Disease
      Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery...
      98% of small molecules and 100% of large molecules do not cross the blood-brain barrier (BBB). Biologics, including therapeutic antibodies (e.g. anti-amyloid antibodies), have been at the for...
      Speaker: Rachita Sumbria, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      FEB 22, 2018 | 12:00 PM
      Commercializing Nanomedicine for Improving Human Health: Not Just Hype, It Is Really Happening!
      Commercializing Nanomedicine for Improving Human Health: Not Just...
      There is an acute shortage of organs due to disease, trauma, congenital defects, and most importantly, age related maladies. The synthetic materials used in tissue engineering applications to...
      Speaker: Thomas Webster, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      2
      FEB 22, 2018 | 10:30 AM
      Illuminating the Druggable GPCR-ome
      Illuminating the Druggable GPCR-ome
      G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
      Speaker: Bryan L. Roth, MD, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      FEB 21, 2018 | 10:30 AM
      Panel Discussion: Co-development of Drugs and Companion Diagnostics
      Panel Discussion: Co-development of Drugs and Companion Diagnostics
      The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
      Speaker: Annette Gilchrist, PhD , Martin Shaw , Thomas Webster, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      FEB 15, 2018 | 10:00 AM
      WEBINAR: Better Answers Faster: Drive Instrument Innovation with 95% QE and Computational Imaging
      WEBINAR: Better Answers Faster: Drive Instrument Innovation with...
      DATE: February 15, 2018TIME: 10:00 AM PST, 1:00 PM ESTModern biomedical instrumentation for research or diagnostic applications often rely on cameras as detectors. Cameras in instrument...
      Speaker: Steve Smith, PhD, MBA
      Sponsored By: Photometrics
      7
      JAN 25, 2018 | 10:00 AM
      WEBINAR:  Engineered Viruses as Precision Cancer Therapeutics
      WEBINAR: Engineered Viruses as Precision Cancer Therapeutics
      DATE: January 25, 2018TIME: 10:00am PST, 1:00pm EST, 6:00pm GMTOncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehi...
      Speaker: Alexander Baker, MSci (Hons), 1st Class
      Sponsored By: Thermo Fisher Scientific/Gibco
      12
      NOV 16, 2017 | 12:00 PM
      WEBINAR: Samples and Data - The Two Layers of Integrations
      WEBINAR: Samples and Data - The Two Layers of Integrations
      DATE: November 16, 2017TIME: 12:00PM PTAutomating complex workflows that require manipulating or assessing samples over days or weeks often require thinking beyond a liquid handler.&nbs...
      Speaker: Russell Green, PhD , Tim Sherrill
      Sponsored By: Beckman Coulter Life Sciences
      3
      NOV 14, 2017 | 9:00 AM
      WEBINAR: CRISPRa tools for transcriptional activation studies
      WEBINAR: CRISPRa tools for transcriptional activation studies
      DATE: November 14, 2017TIME: 09:00am PST, 12:00pm ESTThe CRISPR-Cas9 system has been adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and av...
      Speaker: Žaklina Strezoska , Benedict Cross
      Sponsored By: Dharmacon, a Horizon Discovery Group Company
      11 4
      NOV 08, 2017 | 5:00 PM
      Gibco™ Sera - Driving quality and innovation in a dynamic market
      Gibco™ Sera - Driving quality and innovation in a dynamic market
      In today’s volatile Fetal Bovine Sera market, it is critical for researchers to understand the complex nature of the market especially with demand escalating every year.  The deman...
      Speaker: Matthew Dallas , Christopher Scanlon
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      4
      NOV 02, 2017 | 10:00 AM
      WEBINAR: A CRISPR Way of Making Mice
      WEBINAR: A CRISPR Way of Making Mice
      DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
      Speaker: Joe Miano, PhD
      Sponsored By: Synthego
      12 1
      OCT 24, 2017 | 9:00 AM
      WEBINAR:  Genome Editing for Functional Genomics and Drug Discovery
      WEBINAR: Genome Editing for Functional Genomics and Drug Discovery
      DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
      Speaker: Chetana Revankar , Sanjay Kumar
      Sponsored By: Thermo Fisher Scientific
      4 2
      OCT 12, 2017 | 12:00 PM
      Detection of circulating tumour biomarkers using the FirePlex® Technology Platform
      Detection of circulating tumour biomarkers using the FirePlex®...
      The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
      Speaker: Daniel Pregibon, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      2
      OCT 12, 2017 | 12:00 PM
      Detection of circulating tumour biomarkers using the FirePlex® Technology Platform
      Detection of circulating tumour biomarkers using the FirePlex®...
      The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
      Speaker: Daniel Pregibon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      Sponsored By: Abcam
      1
      OCT 10, 2017 | 7:00 AM
      WEBINAR: Achieving Higher Resolution Protein Impurity Analysis with Microfluidic CE
      WEBINAR: Achieving Higher Resolution Protein Impurity Analysis...
      DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
      Speaker: Anubhav Tripathi, PhD , James White, PhD
      Sponsored By: Revvity
      7
      SEP 28, 2017 | 1:30 PM
      The RRID Initiative, what is needed for scholarship in the 21st century
      The RRID Initiative, what is needed for scholarship in the 21st...
      The Resource Identification Initiative supports NIH's new guidelines for Rigor and Transparency as these apply in biomedical publications. Authors are instructed to authenticate key biolo...
      Speaker: Anita Bandrowski, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
    MAY 30, 2018 | 6:00 AM
    Phenotypic Profiling for Improving Drug Discovery Productivity
    Phenotypic Profiling for Improving Drug Discovery Productivity
    The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
    Speaker: Ellen Berg, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2 1
    MAY 22, 2018 | 8:00 AM
    Drug development with nuclear receptor knockout and humanized rat models
    Drug development with nuclear receptor knockout and humanized...
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    Speaker: Kevin Forbes, PhD , Andrew Brown, MS
    Sponsored By: Horizon Discovery
    5
    MAY 16, 2018 | 8:00 PM
    ExpiCHO High-Efficiency Protein Expression System: Ultra-high Titers Comparable to Stable Transfection Systems Achieved in Two Weeks (Presented in Chinese)
    ExpiCHO High-Efficiency Protein Expression System: Ultra-high...
    ExpiCHO是一种高效的瞬时表达系统,可以在2周内获得与稳定细胞株相当的表达量。 CHO细胞长期以来一直在工业界广泛使用,获得CHO表达蛋白必须构建稳定的细胞株,这一过程不仅耗时耗力,而且需要经验丰富的研发人员。在药物开发阶段需要在较短时间获得大量蛋白,往往只能采用293细胞的瞬转表达系统,但该系统产量低,表达蛋白与CHO系统存在质量差异。ExpiCHO作为高效的瞬时表达系统能...
    Speaker: Yuedan Kong
    Presented at: Gibco ExpressionWorld 2018
    7
    MAY 02, 2018 | 8:00 AM
    Five steps for publication-quality immunohistochemistry imaging
    Five steps for publication-quality immunohistochemistry imaging
    Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
    Speaker: Jason Kilgore
    Sponsored By: Thermo Fisher Scientific
    10
    APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
     
     
  • MAR 27, 2018 | 9:00 AM
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
    Speaker: Amanda Haas
    Sponsored By: Horizon Discovery
    23 15
    MAR 22, 2018 | 9:00 AM
    Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
    Differentiation sensitizes stem-like glioblastoma tumor-initiating...
    DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
    Speaker: Jasmine Hughes
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 4
    MAR 15, 2018 | 10:30 AM
    An Emerging Role of DNA Damage-Repair in Huntington's Disease
    An Emerging Role of DNA Damage-Repair in Huntington's Disease
    Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
    Speaker: Animesh Ray, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
    MAR 15, 2018 | 10:30 AM
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
    The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
    Speaker: Jill Weimer, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    MAR 14, 2018 | 6:00 AM
    Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery of Biologics for Alzheimer's Disease
    Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery...
    98% of small molecules and 100% of large molecules do not cross the blood-brain barrier (BBB). Biologics, including therapeutic antibodies (e.g. anti-amyloid antibodies), have been at the for...
    Speaker: Rachita Sumbria, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
     
     
  • FEB 22, 2018 | 12:00 PM
    Commercializing Nanomedicine for Improving Human Health: Not Just Hype, It Is Really Happening!
    Commercializing Nanomedicine for Improving Human Health: Not Just...
    There is an acute shortage of organs due to disease, trauma, congenital defects, and most importantly, age related maladies. The synthetic materials used in tissue engineering applications to...
    Speaker: Thomas Webster, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    2
    FEB 22, 2018 | 10:30 AM
    Illuminating the Druggable GPCR-ome
    Illuminating the Druggable GPCR-ome
    G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
    Speaker: Bryan L. Roth, MD, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    FEB 21, 2018 | 10:30 AM
    Panel Discussion: Co-development of Drugs and Companion Diagnostics
    Panel Discussion: Co-development of Drugs and Companion Diagnostics
    The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
    Speaker: Annette Gilchrist, PhD , Martin Shaw , Thomas Webster, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    FEB 15, 2018 | 10:00 AM
    WEBINAR: Better Answers Faster: Drive Instrument Innovation with 95% QE and Computational Imaging
    WEBINAR: Better Answers Faster: Drive Instrument Innovation with...
    DATE: February 15, 2018TIME: 10:00 AM PST, 1:00 PM ESTModern biomedical instrumentation for research or diagnostic applications often rely on cameras as detectors. Cameras in instrument...
    Speaker: Steve Smith, PhD, MBA
    Sponsored By: Photometrics
    7
    JAN 25, 2018 | 10:00 AM
    WEBINAR:  Engineered Viruses as Precision Cancer Therapeutics
    WEBINAR: Engineered Viruses as Precision Cancer Therapeutics
    DATE: January 25, 2018TIME: 10:00am PST, 1:00pm EST, 6:00pm GMTOncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehi...
    Speaker: Alexander Baker, MSci (Hons), 1st Class
    Sponsored By: Thermo Fisher Scientific/Gibco
    12
     
     
  • NOV 16, 2017 | 12:00 PM
    WEBINAR: Samples and Data - The Two Layers of Integrations
    WEBINAR: Samples and Data - The Two Layers of Integrations
    DATE: November 16, 2017TIME: 12:00PM PTAutomating complex workflows that require manipulating or assessing samples over days or weeks often require thinking beyond a liquid handler.&nbs...
    Speaker: Russell Green, PhD , Tim Sherrill
    Sponsored By: Beckman Coulter Life Sciences
    3
    NOV 14, 2017 | 9:00 AM
    WEBINAR: CRISPRa tools for transcriptional activation studies
    WEBINAR: CRISPRa tools for transcriptional activation studies
    DATE: November 14, 2017TIME: 09:00am PST, 12:00pm ESTThe CRISPR-Cas9 system has been adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and av...
    Speaker: Žaklina Strezoska , Benedict Cross
    Sponsored By: Dharmacon, a Horizon Discovery Group Company
    11 4
    NOV 08, 2017 | 5:00 PM
    Gibco™ Sera - Driving quality and innovation in a dynamic market
    Gibco™ Sera - Driving quality and innovation in a dynamic market
    In today’s volatile Fetal Bovine Sera market, it is critical for researchers to understand the complex nature of the market especially with demand escalating every year.  The deman...
    Speaker: Matthew Dallas , Christopher Scanlon
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    4
    NOV 02, 2017 | 10:00 AM
    WEBINAR: A CRISPR Way of Making Mice
    WEBINAR: A CRISPR Way of Making Mice
    DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
    Speaker: Joe Miano, PhD
    Sponsored By: Synthego
    12 1
    OCT 24, 2017 | 9:00 AM
    WEBINAR:  Genome Editing for Functional Genomics and Drug Discovery
    WEBINAR: Genome Editing for Functional Genomics and Drug Discovery
    DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
    Speaker: Chetana Revankar , Sanjay Kumar
    Sponsored By: Thermo Fisher Scientific
    4 2
     
     
  • OCT 12, 2017 | 12:00 PM
    Detection of circulating tumour biomarkers using the FirePlex® Technology Platform
    Detection of circulating tumour biomarkers using the FirePlex®...
    The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
    Speaker: Daniel Pregibon, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    2
    OCT 12, 2017 | 12:00 PM
    Detection of circulating tumour biomarkers using the FirePlex® Technology Platform
    Detection of circulating tumour biomarkers using the FirePlex®...
    The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
    Speaker: Daniel Pregibon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    Sponsored By: Abcam
    1
    OCT 10, 2017 | 7:00 AM
    WEBINAR: Achieving Higher Resolution Protein Impurity Analysis with Microfluidic CE
    WEBINAR: Achieving Higher Resolution Protein Impurity Analysis...
    DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
    Speaker: Anubhav Tripathi, PhD , James White, PhD
    Sponsored By: Revvity
    7
    SEP 28, 2017 | 1:30 PM
    The RRID Initiative, what is needed for scholarship in the 21st century
    The RRID Initiative, what is needed for scholarship in the 21st...
    The Resource Identification Initiative supports NIH's new guidelines for Rigor and Transparency as these apply in biomedical publications. Authors are instructed to authenticate key biolo...
    Speaker: Anita Bandrowski, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
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