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    Protein Structure

    Protein Structure: is the three-dimensional arrangement of atoms in an amino acid-chain molecule. ... Proteins form by amino acids undergoing condensation reactions, in which the amino acids lose one water molecule per reaction in order to attach to one another with a peptide bond.

    Webinars

    • MAR 19, 2015 | 3:00 PM
      Early Days of the NIH BRAIN initiative
      Early Days of the NIH BRAIN initiative
      The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
      Speaker: Walter Koroshetz, MD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 19, 2015 | 3:00 PM
      DARPA's Brain Function Research Portfolio
      DARPA's Brain Function Research Portfolio
      DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
      Speaker: Justin Sanchez, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 19, 2015 | 12:00 PM
      Special Lecturer - Towards a Neuroscience of Bipolar Disorder Risk
      Special Lecturer - Towards a Neuroscience of Bipolar Disorder...
      There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
      Speaker: Philip Mitchell AM, MB BS (Hons I), MD, FRANZCP, FRCPsych
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 18, 2015 | 3:00 PM
      The Human Connectome Project
      The Human Connectome Project
      Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
      Speaker: David Van Essen, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 18, 2015 | 10:30 AM
      Special Lecturer - Oxidative Stress in Schizophrenia: a Translational Approach
      Special Lecturer - Oxidative Stress in Schizophrenia: a Translational...
      Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
      Speaker: Kim Quang Do, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      12
      MAR 18, 2015 | 7:30 AM
      Special Lecturer - Circuits of Reward/Motivation and Decisions: Linking Connectivity to Function and Disease
      Special Lecturer - Circuits of Reward/Motivation and Decisions:...
      The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
      Speaker: Suzanne Haber, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      14
      FEB 19, 2015 | 8:00 AM
      Presenting a complete workflow - from start to finish!
      Presenting a complete workflow - from start to finish!
      For more on Gene Editing watch “Webinar: Improve CRISPR-Cas9 experiments with rationally designed guide RNAs” The CRISPR-Cas9 system is being widely used for genome engineering...
      Speaker: Emily Anderson, Ph.D.
      Sponsored By: Dharmacon, Dharmacon
      34 1
      OCT 30, 2014 | 1:30 PM
      Dissecting cancer signaling pathways with chemical scalpels
      Dissecting cancer signaling pathways with chemical scalpels
      Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
      Speaker: Nadya Tarasova, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 1:30 PM
      Structural Pathways of Cancer
      Structural Pathways of Cancer
      Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
      Speaker: Ruth Nussinov, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 29, 2014 | 7:30 AM
      Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
      Targeting the oncogene eIF4E in leukemia reveals a new form of...
      The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
      Speaker: Katherine LB Borden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      40
      OCT 28, 2014 | 8:00 AM
      The identification of single nucleotide and structural variants in gene sequencing
      The identification of single nucleotide and structural variants...
      The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
      Speaker: Max van Min and Laurel Provencher
      Sponsored By: Revvity
      15
      SEP 24, 2014 | 2:00 PM
      Design of protein structures, functions and assemblies
      Design of protein structures, functions and assemblies
      I will describe recent advances in computational protein design which allow the generation of new protein structures and functions. I will describe the use of these methods to design ultra-s...
      Speaker: David Baker, PhD
      Presented at: Advances in Drug Discovery and Development
      32
      SEP 24, 2014 | 12:00 PM
      The Accurate Prediction of Ligand Binding Free Energies
      The Accurate Prediction of Ligand Binding Free Energies
      In the past decade, we have witnessed an explosion in the availability of high-resolution structural information that sheds light on the binding of diverse classes of ligands to both soluble...
      Speaker: Mark Murcko, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      22
      SEP 24, 2014 | 11:00 AM
      Structure based Drug Design for G-protein coupled receptors using the StaR(r) technology
      Structure based Drug Design for G-protein coupled receptors using...
      Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
      Speaker: Fiona Marshall, PhD
      Presented at: Advances in Drug Discovery and Development
      10
      SEP 24, 2014 | 10:00 AM
      The Promises and Challenges of Next-Generation Therapeutics
      The Promises and Challenges of Next-Generation Therapeutics
      The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
      Speaker: Greg Verdine, PhD
      Presented at: Advances in Drug Discovery and Development
      12
      SEP 24, 2014 | 10:00 AM
      Keynote, The Promises and Challenges of Next-Generation Therapeutics
      Keynote, The Promises and Challenges of Next-Generation Therapeutics
      The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
      Speaker: Greg Verdine, PhD
      Presented at: Advances in Drug Discovery and Development
      14
      SEP 24, 2014 | 6:00 AM
      Translational Medicine for Rare Disease: Lessons from Duchenne Muscular Dystrophy
      Translational Medicine for Rare Disease: Lessons from Duchenne...
      Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disease occurring in 1 in 3,500 births, and is uniformly fatal in boys. It is caused by any one of over 50 known mutations in the gen...
      Speaker: Susan Ward, PhD
      Presented at: Advances in Drug Discovery and Development
      14
      SEP 24, 2014 | 5:00 AM
      Exploring macrocycles for drug discovery: Novel lead series for challenging protein-protein interactions
      Exploring macrocycles for drug discovery: Novel lead series for...
      Macrocycles offer a new structural class that has the potential to address challenging protein-protein interaction targets and still present attractive drug-like properties including cell mem...
      Speaker: Nick K. Terrett, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      16
      APR 17, 2014 | 11:00 AM
      A Novel Method of Active Paraffin Removal
      A Novel Method of Active Paraffin Removal
        Formalin Fixation and Paraffin Embedding (FFPE) of tissue samples is a routine practice by pathologists; the technique enables high quality preservation of structural information. However, ...
      Speaker: Hamid Khoja, PhD,
      Sponsored By: Covaris, Covaris
      78
      MAR 20, 2014 | 10:00 AM
      Neuroimaging Informatics: Distributed Resources for 'Big' Cognition
      Neuroimaging Informatics: Distributed Resources for 'Big' Cognition
      Neuroimaging plays a large role in our pursuit of the understanding of behavior and cognition in health and disease. The past decade has seen the emergence of a wealth of resources that suppo...
      Speaker: David N. Kennedy, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      40
      MAR 20, 2014 | 9:00 AM
      BRAIN Initiative Panel Discussion - funding overview
      BRAIN Initiative Panel Discussion - funding overview
      The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By acce...
      Speaker: Story Landis, PhD, Thomas R. Insel, MD, Justin Sanchez, PhD, John C. Wingfield
      Presented at: Neuroscience Virtual Event Series 2014
      102
      MAR 20, 2014 | 8:00 AM
      The Human Connectome Project
      The Human Connectome Project
      ...
      Speaker: David Van Essen, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      100
      MAR 20, 2014 | 7:00 AM
      Tools for Mapping Brain Computations
      Tools for Mapping Brain Computations
      The brain is a complex, densely wired circuit made out of heterogeneous cells, which vary in their shapes, molecular composition, and patterns of connectivity. In order to help discover how n...
      Speaker: Edward S. Boyden, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      62
      MAR 20, 2014 | 6:00 AM
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
      Speaker: Scott W. Emmons, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      54
    MAR 19, 2015 | 3:00 PM
    Early Days of the NIH BRAIN initiative
    Early Days of the NIH BRAIN initiative
    The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
    Speaker: Walter Koroshetz, MD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 19, 2015 | 3:00 PM
    DARPA's Brain Function Research Portfolio
    DARPA's Brain Function Research Portfolio
    DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
    Speaker: Justin Sanchez, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 19, 2015 | 12:00 PM
    Special Lecturer - Towards a Neuroscience of Bipolar Disorder Risk
    Special Lecturer - Towards a Neuroscience of Bipolar Disorder...
    There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
    Speaker: Philip Mitchell AM, MB BS (Hons I), MD, FRANZCP, FRCPsych
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 18, 2015 | 3:00 PM
    The Human Connectome Project
    The Human Connectome Project
    Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
    Speaker: David Van Essen, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 18, 2015 | 10:30 AM
    Special Lecturer - Oxidative Stress in Schizophrenia: a Translational Approach
    Special Lecturer - Oxidative Stress in Schizophrenia: a Translational...
    Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
    Speaker: Kim Quang Do, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    12
     
     
  • MAR 18, 2015 | 7:30 AM
    Special Lecturer - Circuits of Reward/Motivation and Decisions: Linking Connectivity to Function and Disease
    Special Lecturer - Circuits of Reward/Motivation and Decisions:...
    The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
    Speaker: Suzanne Haber, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    14
    FEB 19, 2015 | 8:00 AM
    Presenting a complete workflow - from start to finish!
    Presenting a complete workflow - from start to finish!
    For more on Gene Editing watch “Webinar: Improve CRISPR-Cas9 experiments with rationally designed guide RNAs” The CRISPR-Cas9 system is being widely used for genome engineering...
    Speaker: Emily Anderson, Ph.D.
    Sponsored By: Dharmacon, Dharmacon
    34 1
    OCT 30, 2014 | 1:30 PM
    Dissecting cancer signaling pathways with chemical scalpels
    Dissecting cancer signaling pathways with chemical scalpels
    Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
    Speaker: Nadya Tarasova, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 30, 2014 | 1:30 PM
    Structural Pathways of Cancer
    Structural Pathways of Cancer
    Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
    Speaker: Ruth Nussinov, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 29, 2014 | 7:30 AM
    Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
    Targeting the oncogene eIF4E in leukemia reveals a new form of...
    The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
    Speaker: Katherine LB Borden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    40
     
     
  • OCT 28, 2014 | 8:00 AM
    The identification of single nucleotide and structural variants in gene sequencing
    The identification of single nucleotide and structural variants...
    The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
    Speaker: Max van Min and Laurel Provencher
    Sponsored By: Revvity
    15
    SEP 24, 2014 | 2:00 PM
    Design of protein structures, functions and assemblies
    Design of protein structures, functions and assemblies
    I will describe recent advances in computational protein design which allow the generation of new protein structures and functions. I will describe the use of these methods to design ultra-s...
    Speaker: David Baker, PhD
    Presented at: Advances in Drug Discovery and Development
    32
    SEP 24, 2014 | 12:00 PM
    The Accurate Prediction of Ligand Binding Free Energies
    The Accurate Prediction of Ligand Binding Free Energies
    In the past decade, we have witnessed an explosion in the availability of high-resolution structural information that sheds light on the binding of diverse classes of ligands to both soluble...
    Speaker: Mark Murcko, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    22
    SEP 24, 2014 | 11:00 AM
    Structure based Drug Design for G-protein coupled receptors using the StaR(r) technology
    Structure based Drug Design for G-protein coupled receptors using...
    Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
    Speaker: Fiona Marshall, PhD
    Presented at: Advances in Drug Discovery and Development
    10
    SEP 24, 2014 | 10:00 AM
    The Promises and Challenges of Next-Generation Therapeutics
    The Promises and Challenges of Next-Generation Therapeutics
    The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
    Speaker: Greg Verdine, PhD
    Presented at: Advances in Drug Discovery and Development
    12
     
     
  • SEP 24, 2014 | 10:00 AM
    Keynote, The Promises and Challenges of Next-Generation Therapeutics
    Keynote, The Promises and Challenges of Next-Generation Therapeutics
    The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
    Speaker: Greg Verdine, PhD
    Presented at: Advances in Drug Discovery and Development
    14
    SEP 24, 2014 | 6:00 AM
    Translational Medicine for Rare Disease: Lessons from Duchenne Muscular Dystrophy
    Translational Medicine for Rare Disease: Lessons from Duchenne...
    Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disease occurring in 1 in 3,500 births, and is uniformly fatal in boys. It is caused by any one of over 50 known mutations in the gen...
    Speaker: Susan Ward, PhD
    Presented at: Advances in Drug Discovery and Development
    14
    SEP 24, 2014 | 5:00 AM
    Exploring macrocycles for drug discovery: Novel lead series for challenging protein-protein interactions
    Exploring macrocycles for drug discovery: Novel lead series for...
    Macrocycles offer a new structural class that has the potential to address challenging protein-protein interaction targets and still present attractive drug-like properties including cell mem...
    Speaker: Nick K. Terrett, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    16
    APR 17, 2014 | 11:00 AM
    A Novel Method of Active Paraffin Removal
    A Novel Method of Active Paraffin Removal
      Formalin Fixation and Paraffin Embedding (FFPE) of tissue samples is a routine practice by pathologists; the technique enables high quality preservation of structural information. However, ...
    Speaker: Hamid Khoja, PhD,
    Sponsored By: Covaris, Covaris
    78
    MAR 20, 2014 | 10:00 AM
    Neuroimaging Informatics: Distributed Resources for 'Big' Cognition
    Neuroimaging Informatics: Distributed Resources for 'Big' Cognition
    Neuroimaging plays a large role in our pursuit of the understanding of behavior and cognition in health and disease. The past decade has seen the emergence of a wealth of resources that suppo...
    Speaker: David N. Kennedy, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    40
     
     
  • MAR 20, 2014 | 9:00 AM
    BRAIN Initiative Panel Discussion - funding overview
    BRAIN Initiative Panel Discussion - funding overview
    The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By acce...
    Speaker: Story Landis, PhD, Thomas R. Insel, MD, Justin Sanchez, PhD, John C. Wingfield
    Presented at: Neuroscience Virtual Event Series 2014
    102
    MAR 20, 2014 | 8:00 AM
    The Human Connectome Project
    The Human Connectome Project
    ...
    Speaker: David Van Essen, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    100
    MAR 20, 2014 | 7:00 AM
    Tools for Mapping Brain Computations
    Tools for Mapping Brain Computations
    The brain is a complex, densely wired circuit made out of heterogeneous cells, which vary in their shapes, molecular composition, and patterns of connectivity. In order to help discover how n...
    Speaker: Edward S. Boyden, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    62
    MAR 20, 2014 | 6:00 AM
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
    Speaker: Scott W. Emmons, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    54
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