Translational Research: involves the application of knowledge gained through basic research to studies that could support the development of new products. For example, translational research in the field of medicine may involve using knowledge of the biology of a disease to identify and evaluate chemical compounds in disease models, with a view to selecting potential candidate drugs to advance into clinical trials.
DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
Therapeutic development for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficac...
Dr. Tony Hu’s research focuses on developing and validating integrated nanotechnique-based strategies for marker discovery and molecular diagnostics in peripheral blood samples to provi...
Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
DATE: October 26, 2017TIME: 12:00 PM PDTThis presentation will focus on recent advances in cellular therapy—from mesenchymal stromal cells (MSCs) to tumor-specific T-cells. More s...
DATE: October 26, 2017TIME: 10:00am PT, 1:00pm ETMass spectrometry has gained tremendous interests in clinical applications in the past decade to serve patients needs. W...
DATE: October 25, 2017TIME: 10:00am PDT, 1:00pm EDTTesting for antinuclear antibodies (ANAs) has been a routine part of the evaluation of patients with a suspected connective tissue dis...
DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed. The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%. Although ranking 12th in terms of incidence, it is...
More and more decisions will center on the ability to molecularly characterize a disease. So the molecular diagnostic laboratory will have a pivotal role. What does that look like? Will we be...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
Although the cell is commonly referred to as “the most basic unit of life”, it is actually so complex that despite over 350 years of research we are still far from fully understan...
The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
Actin cytoskeleton drives cell migration in muscle and non-muscle cells and plays a major role in such diverse processes as tissue morphogenesis, muscle contraction, and cancer metastases. In...
Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
DATE: September 26, 2017TIME: 6:00AM PDTDespite a few decades of proteomics research and the apparent discovery of multiple protein biomarkers, the number of biomarkers that have been d...
DATE: September 21, 2017TIME: 8:00AM PSTBoard-certified hematologist-oncologist Ola Landgren, MD, PhD, will review how vague symptoms (fatigue, bone pain, back pain) are linked to...
An unbiased metagenomic next-generation approach (mNGS) been shown to be useful in the broad identification of pathogens in clinical samples for infectious disease diagnosis, including viruse...
Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
Therapeutic development for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficac...
Dr. Tony Hu’s research focuses on developing and validating integrated nanotechnique-based strategies for marker discovery and molecular diagnostics in peripheral blood samples to provi...
Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
DATE: October 26, 2017TIME: 12:00 PM PDTThis presentation will focus on recent advances in cellular therapy—from mesenchymal stromal cells (MSCs) to tumor-specific T-cells. More s...
DATE: October 26, 2017TIME: 10:00am PT, 1:00pm ETMass spectrometry has gained tremendous interests in clinical applications in the past decade to serve patients needs. W...
DATE: October 25, 2017TIME: 10:00am PDT, 1:00pm EDTTesting for antinuclear antibodies (ANAs) has been a routine part of the evaluation of patients with a suspected connective tissue dis...
DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed. The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%. Although ranking 12th in terms of incidence, it is...
More and more decisions will center on the ability to molecularly characterize a disease. So the molecular diagnostic laboratory will have a pivotal role. What does that look like? Will we be...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
Although the cell is commonly referred to as “the most basic unit of life”, it is actually so complex that despite over 350 years of research we are still far from fully understan...
The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
Actin cytoskeleton drives cell migration in muscle and non-muscle cells and plays a major role in such diverse processes as tissue morphogenesis, muscle contraction, and cancer metastases. In...
Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
DATE: September 26, 2017TIME: 6:00AM PDTDespite a few decades of proteomics research and the apparent discovery of multiple protein biomarkers, the number of biomarkers that have been d...
DATE: September 21, 2017TIME: 8:00AM PSTBoard-certified hematologist-oncologist Ola Landgren, MD, PhD, will review how vague symptoms (fatigue, bone pain, back pain) are linked to...
An unbiased metagenomic next-generation approach (mNGS) been shown to be useful in the broad identification of pathogens in clinical samples for infectious disease diagnosis, including viruse...
Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
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