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    ALS

    ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. A-myo-trophic comes from the Greek language. "A" means no. "Myo" refers to muscle, and "Trophic" means nourishment - "No muscle nourishment."

    Webinars

    • MAY 14, 2020 | 12:00 AM
      Animal Models for Tuberculosis Research
      Animal Models for Tuberculosis Research
      Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
      Speaker: Yong Cheng, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      2
      MAY 14, 2020 | 12:00 AM
      Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel Cage-Side Measures
      Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel...
      The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
      Speaker: Jennifer Lofgren, DVM, MS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      MAY 14, 2020 | 12:00 AM
      Compassion Fatigue: Education and Engagement in Animal Research
      Compassion Fatigue: Education and Engagement in Animal Research
      Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the...
      Speaker: Marian Esvelt, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      1
      MAY 14, 2020 | 12:00 AM
      Comparison of the Impact of Phlebotomy Method on Physiologic and Behavioral Metrics of Pain and Distress in Mice
      Comparison of the Impact of Phlebotomy Method on Physiologic and...
      Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimiz...
      Speaker: Elizabeth Moore, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      MAY 14, 2020 | 12:00 AM
      The Digitalization of the Vivarium: Past and Present Initiatives that Optimize Animal Care and Welfare
      The Digitalization of the Vivarium: Past and Present Initiatives...
      Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some of way...
      Speaker: John J. Hasenau DVM, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      MAY 14, 2020 | 12:00 AM
      Automatic Detection and Classification of Behaviour in Laboratory Animals
      Automatic Detection and Classification of Behaviour in Laboratory...
      Animal welfare is the most important issue in any in vivo laboratory. The ability to detect and intervene in cases where the conditions of animals may be deteriorating as well as the ability...
      Speaker: Patrick Sweeney, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      APR 29, 2020 | 6:00 AM
      Using a Multiplex Suspension Bead Assay to Establish a Serocorrelate of Protection for Group B Streptococcus Disease
      Using a Multiplex Suspension Bead Assay to Establish a Serocorrelate...
      Purpose: Group B Streptococcus (GBS) is a Gram positive coccus which is part of the normal microbiota of the GI and GU tracts. However GBS is also a major cause of septicaemia and meningitis...
      Speaker: Tom Hall
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 22, 2020 | 12:00 AM
      Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
      Long-range technologies resolve complex genomic regions overlooked...
      Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
      Speaker: Mark Ebbert, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 14, 2020 | 9:00 AM
      Gibco Cell Culture Heroes: Work From Home Edition
      Gibco Cell Culture Heroes: Work From Home Edition
      DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
      Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12 1
      MAR 27, 2020 | 9:00 AM
      Modified Dental Composite for Bone Repair
      Modified Dental Composite for Bone Repair
      DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
      Speaker: Mayda Arshad
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      MAR 11, 2020 | 10:30 AM
      Innate immunity in chronic neurodegeneration
      Innate immunity in chronic neurodegeneration
      The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
      Speaker: Michael Heneka, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      FEB 25, 2020 | 10:00 AM
      Avances en la Tecnología del Diferencial de Glóbulos Blancos
      Avances en la Tecnología del Diferencial de Glóbulos Blancos
      DATE: 25 Febrero 2020 TIME: 13:00 COT, 10:00 PST Los desarrollos tecnológicos en analizadores automatizados de Hematología continúan transformando el laboratorio de Hema...
      Speaker: Don Wright
      Sponsored By: Abbott
      5 1
      JAN 30, 2020 | 9:00 AM
      An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
      An Automated Cancer Organoid Culture Platform to Accelerate Research...
      DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
      Speaker: Brooke Schuster
      Sponsored By: Thermo Fisher Scientific/Gibco
      10
      JAN 01, 2020 | 6:00 AM
      Multi-region Neural Network Models of Adaptive and Maladaptive Learning in the Brain
      Multi-region Neural Network Models of Adaptive and Maladaptive...
      In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
      Speaker: Kanaka Rajan, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      DEC 17, 2019 | 9:00 AM
      The role of SIRT1/LXR signaling in diabetic retinopathy
      The role of SIRT1/LXR signaling in diabetic retinopathy
      DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
      Speaker: Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      NOV 25, 2019 | 9:00 AM
      TECNOLOGÍA DE HEMATOLOGÍA ÓPTICA AVANZADA PARA UN MEJOR DESEMPEÑO ANALÍTICO
      TECNOLOGÍA DE HEMATOLOGÍA ÓPTICA AVANZADA PARA UN MEJOR DESEMPEÑO...
      FECHA: 25 Noviembre 2019 TIEMPO: 12:00PM UTC-5, 9:00AM PST Hoy en día, los analizadores de hematología pueden recopilar grandes cantidades de datos acerca de las caracter&...
      Speaker: Zainab Mukhatar, MD
      Sponsored By: Abbott
      16 10
      NOV 21, 2019 | 9:00 AM
      The role of immune cells and immune checkpoints in multiple myeloma
      The role of immune cells and immune checkpoints in multiple myeloma
      DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
      Speaker: Nathalie Heider-Hönatsch, M.Sc.
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      OCT 09, 2019 | 10:30 AM
      Newly Diagnosed Ovarian Cancer: Surgical Options
      Newly Diagnosed Ovarian Cancer: Surgical Options
      A subset of women with ovarian cancer will present with an apparently isolated adnexal mass. Many of these women will have early stage ovarian cancer with a relatively good prognosis. Unfortu...
      Speaker: Mitchel Hoffman, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      2
      OCT 03, 2019 | 1:30 PM
      Re-examining the ethical & regulatory dimensions of gene editing in the wake of the "CRISPR babies" scandal
      Re-examining the ethical & regulatory dimensions of gene editing...
      Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
      Speaker: Erika Kleiderman, B.Sc. , LL.B.
      Presented at: CRISPR Virtual Event Series 2019
      3
      OCT 03, 2019 | 7:30 AM
      Keynote Presentation: CRISPR/Cas9 genome editing in mouse and rat: The PHENOMIN-ICS experience
      Keynote Presentation: CRISPR/Cas9 genome editing in mouse and...
      CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
      Speaker: Marie-Christine Birling, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      SEP 26, 2019 | 6:00 AM
      Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics and the Challenge of Low Input Samples
      Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics...
      Spatial transcriptomics methods permit gene expression from focal areas within a tissue to be profiled while maintaining the morphologic context of the tissue microenvironment. This presentat...
      Speaker: Bruce Seligmann, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      1
      JUL 24, 2019 | 8:00 AM
      Establishing a robust 37-marker mass cytometry assay for deep single-cell immune profiling of whole blood
      Establishing a robust 37-marker mass cytometry assay for deep...
      DATE: July 24, 2019TIMEL 8:00am PT Mass cytometry (CyTOF®) is a powerful approach to characterize the immune composition of complex biological specimens and gain insights in...
      Speaker: Adeeb Rahman, PhD , Mona Al-Maarri, PhD
      Sponsored By: Miltenyi Biotec
      8
    MAY 14, 2020 | 12:00 AM
    Animal Models for Tuberculosis Research
    Animal Models for Tuberculosis Research
    Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
    Speaker: Yong Cheng, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    2
    MAY 14, 2020 | 12:00 AM
    Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel Cage-Side Measures
    Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel...
    The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
    Speaker: Jennifer Lofgren, DVM, MS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
    MAY 14, 2020 | 12:00 AM
    Compassion Fatigue: Education and Engagement in Animal Research
    Compassion Fatigue: Education and Engagement in Animal Research
    Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the...
    Speaker: Marian Esvelt, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    1
    MAY 14, 2020 | 12:00 AM
    Comparison of the Impact of Phlebotomy Method on Physiologic and Behavioral Metrics of Pain and Distress in Mice
    Comparison of the Impact of Phlebotomy Method on Physiologic and...
    Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimiz...
    Speaker: Elizabeth Moore, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
    MAY 14, 2020 | 12:00 AM
    The Digitalization of the Vivarium: Past and Present Initiatives that Optimize Animal Care and Welfare
    The Digitalization of the Vivarium: Past and Present Initiatives...
    Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some of way...
    Speaker: John J. Hasenau DVM, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
     
     
  • MAY 14, 2020 | 12:00 AM
    Automatic Detection and Classification of Behaviour in Laboratory Animals
    Automatic Detection and Classification of Behaviour in Laboratory...
    Animal welfare is the most important issue in any in vivo laboratory. The ability to detect and intervene in cases where the conditions of animals may be deteriorating as well as the ability...
    Speaker: Patrick Sweeney, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    1
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    APR 29, 2020 | 6:00 AM
    Using a Multiplex Suspension Bead Assay to Establish a Serocorrelate of Protection for Group B Streptococcus Disease
    Using a Multiplex Suspension Bead Assay to Establish a Serocorrelate...
    Purpose: Group B Streptococcus (GBS) is a Gram positive coccus which is part of the normal microbiota of the GI and GU tracts. However GBS is also a major cause of septicaemia and meningitis...
    Speaker: Tom Hall
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 22, 2020 | 12:00 AM
    Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
    Long-range technologies resolve complex genomic regions overlooked...
    Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
    Speaker: Mark Ebbert, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 14, 2020 | 9:00 AM
    Gibco Cell Culture Heroes: Work From Home Edition
    Gibco Cell Culture Heroes: Work From Home Edition
    DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
    Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12 1
     
     
  • MAR 27, 2020 | 9:00 AM
    Modified Dental Composite for Bone Repair
    Modified Dental Composite for Bone Repair
    DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
    Speaker: Mayda Arshad
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    MAR 11, 2020 | 10:30 AM
    Innate immunity in chronic neurodegeneration
    Innate immunity in chronic neurodegeneration
    The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
    Speaker: Michael Heneka, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    FEB 25, 2020 | 10:00 AM
    Avances en la Tecnología del Diferencial de Glóbulos Blancos
    Avances en la Tecnología del Diferencial de Glóbulos Blancos
    DATE: 25 Febrero 2020 TIME: 13:00 COT, 10:00 PST Los desarrollos tecnológicos en analizadores automatizados de Hematología continúan transformando el laboratorio de Hema...
    Speaker: Don Wright
    Sponsored By: Abbott
    5 1
    JAN 30, 2020 | 9:00 AM
    An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
    An Automated Cancer Organoid Culture Platform to Accelerate Research...
    DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
    Speaker: Brooke Schuster
    Sponsored By: Thermo Fisher Scientific/Gibco
    10
    JAN 01, 2020 | 6:00 AM
    Multi-region Neural Network Models of Adaptive and Maladaptive Learning in the Brain
    Multi-region Neural Network Models of Adaptive and Maladaptive...
    In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
    Speaker: Kanaka Rajan, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
     
     
  • DEC 17, 2019 | 9:00 AM
    The role of SIRT1/LXR signaling in diabetic retinopathy
    The role of SIRT1/LXR signaling in diabetic retinopathy
    DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
    Speaker: Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    NOV 25, 2019 | 9:00 AM
    TECNOLOGÍA DE HEMATOLOGÍA ÓPTICA AVANZADA PARA UN MEJOR DESEMPEÑO ANALÍTICO
    TECNOLOGÍA DE HEMATOLOGÍA ÓPTICA AVANZADA PARA UN MEJOR DESEMPEÑO...
    FECHA: 25 Noviembre 2019 TIEMPO: 12:00PM UTC-5, 9:00AM PST Hoy en día, los analizadores de hematología pueden recopilar grandes cantidades de datos acerca de las caracter&...
    Speaker: Zainab Mukhatar, MD
    Sponsored By: Abbott
    16 10
    NOV 21, 2019 | 9:00 AM
    The role of immune cells and immune checkpoints in multiple myeloma
    The role of immune cells and immune checkpoints in multiple myeloma
    DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
    Speaker: Nathalie Heider-Hönatsch, M.Sc.
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
    OCT 09, 2019 | 10:30 AM
    Newly Diagnosed Ovarian Cancer: Surgical Options
    Newly Diagnosed Ovarian Cancer: Surgical Options
    A subset of women with ovarian cancer will present with an apparently isolated adnexal mass. Many of these women will have early stage ovarian cancer with a relatively good prognosis. Unfortu...
    Speaker: Mitchel Hoffman, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    2
     
     
  • OCT 03, 2019 | 1:30 PM
    Re-examining the ethical & regulatory dimensions of gene editing in the wake of the "CRISPR babies" scandal
    Re-examining the ethical & regulatory dimensions of gene editing...
    Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
    Speaker: Erika Kleiderman, B.Sc. , LL.B.
    Presented at: CRISPR Virtual Event Series 2019
    3
    OCT 03, 2019 | 7:30 AM
    Keynote Presentation: CRISPR/Cas9 genome editing in mouse and rat: The PHENOMIN-ICS experience
    Keynote Presentation: CRISPR/Cas9 genome editing in mouse and...
    CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
    Speaker: Marie-Christine Birling, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    SEP 26, 2019 | 6:00 AM
    Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics and the Challenge of Low Input Samples
    Profiling Focal Areas of FFPE Tissue: Spatial Transcriptomics...
    Spatial transcriptomics methods permit gene expression from focal areas within a tissue to be profiled while maintaining the morphologic context of the tissue microenvironment. This presentat...
    Speaker: Bruce Seligmann, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    1
    JUL 24, 2019 | 8:00 AM
    Establishing a robust 37-marker mass cytometry assay for deep single-cell immune profiling of whole blood
    Establishing a robust 37-marker mass cytometry assay for deep...
    DATE: July 24, 2019TIMEL 8:00am PT Mass cytometry (CyTOF®) is a powerful approach to characterize the immune composition of complex biological specimens and gain insights in...
    Speaker: Adeeb Rahman, PhD , Mona Al-Maarri, PhD
    Sponsored By: Miltenyi Biotec
    8
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