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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • SEP 30, 2015 | 1:30 PM
      SuperSelective Primers for the Multiplex Quantitation of Rare Mutant Sequences Associated with Cancer
      SuperSelective Primers for the Multiplex Quantitation of Rare...
      A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 12:00 PM
      Modeling and dissecting hepatocellular carcinoma dissemination
      Modeling and dissecting hepatocellular carcinoma dissemination
      Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
      Speaker: Brian Lewis, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 10:30 AM
      High efficiency SPRI (Solid Phase Reverse Immobilization Paramagnetic Bead) technology for microRNA applications
      High efficiency SPRI (Solid Phase Reverse Immobilization Paramagnetic...
      Micro RNAs (miRNAs) are small, naturally-occurring non-coding ribonucleic acids with sizes between 18 and 40 nucleotides (nts) that have been demonstrated to play a significant role in the re...
      Speaker: Bee Na Lee, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences
      2
      SEP 30, 2015 | 9:00 AM
      Lactate-driven metabolic adaptation modulates breast cancer progression
      Lactate-driven metabolic adaptation modulates breast cancer progression
      The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
      Speaker: Jennifer Molina, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 7:30 AM
      Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
      Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
      Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
      Speaker: Brian Soper, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 6:00 AM
      Comparative genome and transcriptome analysis of small cell numbers
      Comparative genome and transcriptome analysis of small cell numbers
      The genome determines changes of the transcription profile upon environmental changes and finally determines how a cell reacts. A comparative genome and transcriptome analysis of the same sam...
      Speaker: Christian Korfhage, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 22, 2015 | 8:00 AM
      WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable Materials
      WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable...
      Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate t...
      Speaker: Erin Gaddes, MS
      Sponsored By: Ametek, Ametek
      5
      SEP 17, 2015 | 7:30 AM
      WEBINAR: Lab sustainability: keeping the planet and your wallet green
      WEBINAR: Lab sustainability: keeping the planet and your wallet...
      DATE: September 17, 2015TIME: 7:30AM PDT, 10:30AM EDTAs technology advances and globalization develops, our way of life has become more dependent on energy sources to power our everyday activ...
      Speaker: Daniela Marino
      Sponsored By: Eppendorf, Eppendorf
      4
      SEP 16, 2015 | 12:00 PM
      Developing Accurate Nanomedicines: The BIND Therapeutics Approach
      Developing Accurate Nanomedicines: The BIND Therapeutics Approach
      Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurinâ„¢ nanomedicines that utilize cytotoxic age...
      Speaker: Hagop Youssoufian
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      SEP 15, 2015 | 10:00 AM
      A new integrated platform for high quality and low cost gene expression analysis
      A new integrated platform for high quality and low cost gene expression...
      DATE: September 15, 2015TIME: 10:00AM Pacific time, 1:00PM Eastern timeThe breadth of instruments available for quantitative PCR (qPCR) has continued to grow in the past 5-10 years. With ...
      Speaker: Mikael Kubista , Ross Higgins
      Sponsored By: Douglas Scientific, Douglas Scientific
      4
      SEP 15, 2015 | 8:00 AM
      WEBINAR: Advances in Live Cell Imaging
      WEBINAR: Advances in Live Cell Imaging
      DATE: September 15, 2015TIME: 8:00AM PT, 11:00AM ETSkin Cell Motility: Integrins Lead the WayYou will learn about efforts to dissect mechanisms that underlie the directed migration of epiderm...
      Speaker: Jonathan Jones, PhD , Jennifer Horner, PhD , Bernard Kleine
      Sponsored By: Leica Microsystems, Leica Microsystems
      5
      SEP 15, 2015 | 7:00 AM
      WEBINAR: Less False Negatives: Quantifying Cell Viability by Simultaneous Triple Staining
      WEBINAR: Less False Negatives: Quantifying Cell Viability by Simultaneous...
      Cellular viability is usually determined by measuring the capacity of cells to exclude vital dyes such as 4',6-diamidino-2-phenylindole (DAPI), or by assessing nuclear morphology with chr...
      Speaker: Oliver Kepp, PhD , Allan Sauvat
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      5 2
      SEP 10, 2015 | 4:00 AM
      WEBINAR: Visualizing & Tracking: Extracellular Vesicles Delivery and RNA Translation
      WEBINAR: Visualizing & Tracking: Extracellular Vesicles Delivery...
      The webinar will start at 4am Pacific Time, 7am Eastern Time, 1pm Central European Summer Time, 7pm China Standard Time   Extracellular vesicles (EVs) including exosome and microvesi...
      Speaker: Charles Lai, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      8
      SEP 03, 2015 | 1:30 PM
      Challenges of Natural Preservative Application
      Challenges of Natural Preservative Application
      Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
      Speaker: Philip Geis, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2 1
      SEP 03, 2015 | 7:30 AM
      Keynote: Using New Technology to Control Healthcare Associated Disease
      Keynote: Using New Technology to Control Healthcare Associated...
      Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
      Speaker: Lance Peterson, MD, FASCP, FIDSA, FAAM, FSHEA
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 12:00 PM
      Polyamines in bacterial growth and biofilm formation
      Polyamines in bacterial growth and biofilm formation
      Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
      Speaker: Anthony Michael, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      SEP 02, 2015 | 10:30 AM
      Growing together:  Lessons learned from the characterization of the pediatric microbiome
      Growing together: Lessons learned from the characterization of...
      Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
      Speaker: Emily Hollister, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 9:00 AM
      Keynote: Immunology and the Microbiome
      Keynote: Immunology and the Microbiome
      The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
      Speaker: Jack Gilbert, BSc, PhD
      Presented at: Microbiology Virtual Event Series 2015
      10
      SEP 02, 2015 | 6:00 AM
      Structure and Function of the Human Microbiome
      Structure and Function of the Human Microbiome
      Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
      Speaker: Curtis Huttenhower, PhD
      Presented at: Microbiology Virtual Event Series 2015
      9
      SEP 02, 2015 | 6:00 AM
      Simple, fast and accurate microbial identification by sequencing
      Simple, fast and accurate microbial identification by sequencing
      Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
      Speaker: Jane Luo, PhD
      Presented at: Microbiology Virtual Event Series 2015
      9
      AUG 20, 2015 | 8:00 AM
      WEBINAR: Light Sheet Microscopy for Tissue Clearing Applications & 3D Live Fluorescent Imaging
      WEBINAR: Light Sheet Microscopy for Tissue Clearing Applications...
      DATE: August 20, 2015TIME: 8:00am PDT, 11:00am EDT, 4:00pm BSTLight Sheet Microscopy for 3D live fluorescent imaging at high spatiotemporal resolution Dr Bi-Chang Chen will discuss his ...
      Speaker: Bi-Chang Chen, PhD , Alon Greenbaum, MS , Orla Hanrahan, PhD
      Sponsored By: Andor, Andor
      8
      JUN 24, 2015 | 9:00 AM
      Solarisâ„¢ - A novel open-air fluorescence imaging system for image-guided surgery applications
      Solarisâ„¢ - A novel open-air fluorescence imaging system for image-guided...
      Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solarisâ„¢ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
      Speaker: Wael Yared, PhD , Jeffrey Peterson, PhD
      Sponsored By: Revvity
      12 1
      JUN 17, 2015 | 8:00 AM
      Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
      Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
      DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
      Speaker: Mark Landers
      Sponsored By: Epic Sciences, Epic Sciences
      15 2
      JUN 11, 2015 | 11:00 AM
      Assessing Quality Using ACCURUN® Controls for Quantitative Viral Load Assays
      Assessing Quality Using ACCURUN® Controls for Quantitative Viral...
      Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
      Speaker: Russell Garlick
      Presented at: Cardinal Health labXchange
      Sponsored By: Cardinal Healthâ„¢ OptiFreight® Logistics
      6
    SEP 30, 2015 | 1:30 PM
    SuperSelective Primers for the Multiplex Quantitation of Rare Mutant Sequences Associated with Cancer
    SuperSelective Primers for the Multiplex Quantitation of Rare...
    A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 12:00 PM
    Modeling and dissecting hepatocellular carcinoma dissemination
    Modeling and dissecting hepatocellular carcinoma dissemination
    Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
    Speaker: Brian Lewis, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 10:30 AM
    High efficiency SPRI (Solid Phase Reverse Immobilization Paramagnetic Bead) technology for microRNA applications
    High efficiency SPRI (Solid Phase Reverse Immobilization Paramagnetic...
    Micro RNAs (miRNAs) are small, naturally-occurring non-coding ribonucleic acids with sizes between 18 and 40 nucleotides (nts) that have been demonstrated to play a significant role in the re...
    Speaker: Bee Na Lee, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences
    2
    SEP 30, 2015 | 9:00 AM
    Lactate-driven metabolic adaptation modulates breast cancer progression
    Lactate-driven metabolic adaptation modulates breast cancer progression
    The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
    Speaker: Jennifer Molina, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 7:30 AM
    Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
    Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
    Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
    Speaker: Brian Soper, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
     
     
  • SEP 30, 2015 | 6:00 AM
    Comparative genome and transcriptome analysis of small cell numbers
    Comparative genome and transcriptome analysis of small cell numbers
    The genome determines changes of the transcription profile upon environmental changes and finally determines how a cell reacts. A comparative genome and transcriptome analysis of the same sam...
    Speaker: Christian Korfhage, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 22, 2015 | 8:00 AM
    WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable Materials
    WEBINAR: SPR for Aptamer-Based Molecular Interactions in Programmable...
    Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate t...
    Speaker: Erin Gaddes, MS
    Sponsored By: Ametek, Ametek
    5
    SEP 17, 2015 | 7:30 AM
    WEBINAR: Lab sustainability: keeping the planet and your wallet green
    WEBINAR: Lab sustainability: keeping the planet and your wallet...
    DATE: September 17, 2015TIME: 7:30AM PDT, 10:30AM EDTAs technology advances and globalization develops, our way of life has become more dependent on energy sources to power our everyday activ...
    Speaker: Daniela Marino
    Sponsored By: Eppendorf, Eppendorf
    4
    SEP 16, 2015 | 12:00 PM
    Developing Accurate Nanomedicines: The BIND Therapeutics Approach
    Developing Accurate Nanomedicines: The BIND Therapeutics Approach
    Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurinâ„¢ nanomedicines that utilize cytotoxic age...
    Speaker: Hagop Youssoufian
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    SEP 15, 2015 | 10:00 AM
    A new integrated platform for high quality and low cost gene expression analysis
    A new integrated platform for high quality and low cost gene expression...
    DATE: September 15, 2015TIME: 10:00AM Pacific time, 1:00PM Eastern timeThe breadth of instruments available for quantitative PCR (qPCR) has continued to grow in the past 5-10 years. With ...
    Speaker: Mikael Kubista , Ross Higgins
    Sponsored By: Douglas Scientific, Douglas Scientific
    4
     
     
  • SEP 15, 2015 | 8:00 AM
    WEBINAR: Advances in Live Cell Imaging
    WEBINAR: Advances in Live Cell Imaging
    DATE: September 15, 2015TIME: 8:00AM PT, 11:00AM ETSkin Cell Motility: Integrins Lead the WayYou will learn about efforts to dissect mechanisms that underlie the directed migration of epiderm...
    Speaker: Jonathan Jones, PhD , Jennifer Horner, PhD , Bernard Kleine
    Sponsored By: Leica Microsystems, Leica Microsystems
    5
    SEP 15, 2015 | 7:00 AM
    WEBINAR: Less False Negatives: Quantifying Cell Viability by Simultaneous Triple Staining
    WEBINAR: Less False Negatives: Quantifying Cell Viability by Simultaneous...
    Cellular viability is usually determined by measuring the capacity of cells to exclude vital dyes such as 4',6-diamidino-2-phenylindole (DAPI), or by assessing nuclear morphology with chr...
    Speaker: Oliver Kepp, PhD , Allan Sauvat
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    5 2
    SEP 10, 2015 | 4:00 AM
    WEBINAR: Visualizing & Tracking: Extracellular Vesicles Delivery and RNA Translation
    WEBINAR: Visualizing & Tracking: Extracellular Vesicles Delivery...
    The webinar will start at 4am Pacific Time, 7am Eastern Time, 1pm Central European Summer Time, 7pm China Standard Time   Extracellular vesicles (EVs) including exosome and microvesi...
    Speaker: Charles Lai, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    8
    SEP 03, 2015 | 1:30 PM
    Challenges of Natural Preservative Application
    Challenges of Natural Preservative Application
    Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
    Speaker: Philip Geis, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2 1
    SEP 03, 2015 | 7:30 AM
    Keynote: Using New Technology to Control Healthcare Associated Disease
    Keynote: Using New Technology to Control Healthcare Associated...
    Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
    Speaker: Lance Peterson, MD, FASCP, FIDSA, FAAM, FSHEA
    Presented at: Microbiology Virtual Event Series 2015
    2
     
     
  • SEP 02, 2015 | 12:00 PM
    Polyamines in bacterial growth and biofilm formation
    Polyamines in bacterial growth and biofilm formation
    Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
    Speaker: Anthony Michael, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
    SEP 02, 2015 | 10:30 AM
    Growing together:  Lessons learned from the characterization of the pediatric microbiome
    Growing together: Lessons learned from the characterization of...
    Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
    Speaker: Emily Hollister, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 9:00 AM
    Keynote: Immunology and the Microbiome
    Keynote: Immunology and the Microbiome
    The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
    Speaker: Jack Gilbert, BSc, PhD
    Presented at: Microbiology Virtual Event Series 2015
    10
    SEP 02, 2015 | 6:00 AM
    Structure and Function of the Human Microbiome
    Structure and Function of the Human Microbiome
    Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
    Speaker: Curtis Huttenhower, PhD
    Presented at: Microbiology Virtual Event Series 2015
    9
    SEP 02, 2015 | 6:00 AM
    Simple, fast and accurate microbial identification by sequencing
    Simple, fast and accurate microbial identification by sequencing
    Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
    Speaker: Jane Luo, PhD
    Presented at: Microbiology Virtual Event Series 2015
    9
     
     
  • AUG 20, 2015 | 8:00 AM
    WEBINAR: Light Sheet Microscopy for Tissue Clearing Applications & 3D Live Fluorescent Imaging
    WEBINAR: Light Sheet Microscopy for Tissue Clearing Applications...
    DATE: August 20, 2015TIME: 8:00am PDT, 11:00am EDT, 4:00pm BSTLight Sheet Microscopy for 3D live fluorescent imaging at high spatiotemporal resolution Dr Bi-Chang Chen will discuss his ...
    Speaker: Bi-Chang Chen, PhD , Alon Greenbaum, MS , Orla Hanrahan, PhD
    Sponsored By: Andor, Andor
    8
    JUN 24, 2015 | 9:00 AM
    Solarisâ„¢ - A novel open-air fluorescence imaging system for image-guided surgery applications
    Solarisâ„¢ - A novel open-air fluorescence imaging system for image-guided...
    Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solarisâ„¢ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
    Speaker: Wael Yared, PhD , Jeffrey Peterson, PhD
    Sponsored By: Revvity
    12 1
    JUN 17, 2015 | 8:00 AM
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    Sponsored By: Epic Sciences, Epic Sciences
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    Presented at: Cardinal Health labXchange
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