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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • FEB 08, 2017 | 10:30 AM
      Biosecurity, Reproductive and Social Management of Cat Research Colonies
      Biosecurity, Reproductive and Social Management of Cat Research...
      DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
      Speaker: James Kehler VMD, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 08, 2017 | 10:30 AM
      Obtaining non-invasive readouts and early safety signals from rodent models
      Obtaining non-invasive readouts and early safety signals from...
      DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
      FEB 08, 2017 | 9:00 AM
      Evaluating the Effectiveness of Training  for Animal Care and Use Personnel
      Evaluating the Effectiveness of Training for Animal Care and...
      DATE: February 8, 2017TIME: 9:00am PT, Noon ETTraining programs for animal care and use personnel are integral to both animal welfare and quality research outcomes. There are a variety...
      Speaker: Melissa Dyson MS, DVM, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 08, 2017 | 6:00 AM
      Impact of Two Formulations of Buprenorphine on Postsurgical Condition in Mice
      Impact of Two Formulations of Buprenorphine on Postsurgical Condition...
      DATE: February 8, 2017TIME: 6:00am PT, 9:00 ETSeveral regulatory bodies require that animals used in biomedical and behavioral research exposed to procedures that may cause more th...
      Speaker: Nicole Herndon, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      7
      DEC 14, 2016 | 7:30 AM
      Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
      Advances in modeling human diseases using induced pluripotent...
      DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
      Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      7 1
      DEC 01, 2016 | 8:00 AM
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
      DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
      Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
      Sponsored By: Revvity
      3
      NOV 17, 2016 | 7:00 AM
      Using patient-derived iPSCs to model and treat inherited retinal degenerative blindness
      Using patient-derived iPSCs to model and treat inherited retinal...
      Inherited retinal degenerative disorders such as retinitis pigmentosa are characterized by death of the light sensing photoreceptive neurons of the outer retina. Like the rest of the CNS, the...
      Speaker: KEYNOTE: Budd Tucker, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      6
      NOV 17, 2016 | 3:00 AM
      Genetic variability of ps-iPSC and related blood and fibroblasts - somatic mutations
      Genetic variability of ps-iPSC and related blood and fibroblasts...
      The generation of induced pluripotent stem cells (iPSCs) from adult easily accessible somatic tissues was introduced ten years ago. This technology has revolutionized our opportunities to stu...
      Speaker: KEYNOTE: Silke Rickert-Sperling, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      8 1
      NOV 16, 2016 | 4:00 PM
      Evolving your media system for modern stem cell applications
      Evolving your media system for modern stem cell applications
      Culture systems for pluripotent stem cell (PSC) expansion enable generation of a nearly unlimited pool of cells for downstream differentiation, disease modeling, drug discovery, and therapeut...
      Speaker: Rhonda Newman, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      NOV 15, 2016 | 9:00 AM
      Antigen-specific, poly-functional CD4+ T cells are required for vaccine-mediated protection in tularemia
      Antigen-specific, poly-functional CD4+ T cells are required for...
      DATE: November 15, 2016 TIME: 9:00 AM PT, 12:00 PM ET The virulent intracellular pathogen Francisella tularensis subsp. tularensis (Ftt) causes an acute, lethal diseas...
      Speaker: Lydia Roberts, PhD
      Sponsored By: Miltenyi Biotec, Miltenyi Biotec
      3
      NOV 10, 2016 | 9:00 AM
      CellSimpleâ„¢ Cell Analyzer: Delivering Convenience, Versatility and Efficiency for Your Application Workflows
      CellSimpleâ„¢ Cell Analyzer: Delivering Convenience, Versatility...
      DATE:  November 10, 2016 TIME:  9:00am PT, Noon ET The CellSimple™ Cell Analyzer enables quick and easy research assays, including functional cell-based assays, cell-model...
      Speaker: Jonah Riddell, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      2
      NOV 09, 2016 | 8:00 AM
      ProEnkephalin:(PENK).  New Biomarker and Novel Window to Kidney Function: Emerging new data of ProEnkephalin in Clinical Populations
      ProEnkephalin:(PENK). New Biomarker and Novel Window to Kidney...
      DATE:  November 9, 2016 TIME:  8:00am PT, 11:00am ET This talk will characterize the current clinical and laboratory standards for determining risk for chronic renal dysfunction...
      Speaker: Ravindra Mehta, MD , Alan Maisel, M.D. , Olle Melander, MD, PhD
      Sponsored By: Sphingotec LLC, Sphingotec LLC
      3
      NOV 03, 2016 | 12:00 PM
      Point of Care Testing - Why Knowing Now Matters in the Emergency Department
      Point of Care Testing - Why Knowing Now Matters in the Emergency...
      There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes.  There is an association between waiting times and short term mo...
      Speaker: Ellis Jacobs, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      0
      NOV 02, 2016 | 10:30 AM
      Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
      Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
      Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
      Speaker: Sebastiano Gattoni-Celli, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      OCT 18, 2016 | 1:00 PM
      The Role of 3D Culture Methods in Retaining Native Biological Properties of Translational In Vitro Models
      The Role of 3D Culture Methods in Retaining Native Biological...
      Cell Sciences Innovation, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ USA In vitro translational models play a critical role in the drug discovery process because t...
      Speaker: Richard Visconti, PhD
      Presented at: SyncD³ - Where drug discovery & development meet
      0
      OCT 18, 2016 | 1:00 PM
      Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative Medicine Models of Brain Diseases
      Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative...
      Induced pluripotent stem cells derived from patient cells have emerged as complementary tools to study human neurological disorders.  Neurxstem Inc has generated human iPSC-derived synth...
      Speaker: Rene Anand, PhD
      Presented at: SyncD³ - Where drug discovery & development meet
      0
      OCT 18, 2016 | 9:00 AM
      Genome Editing of Human Pluripotent Stem Cells to Generate Human Cellular Disease Models
      Genome Editing of Human Pluripotent Stem Cells to Generate Human...
      ...
      Speaker: Kiran Musunuru, MD, PhD, MPH
      Presented at: SyncD³ - Where drug discovery & development meet
      0
      SEP 08, 2016 | 12:00 PM
      Plant Viruses: Everywhere and Often Mutualistic
      Plant Viruses: Everywhere and Often Mutualistic
       Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
      Speaker: Marilyn Roossinck, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      4
      SEP 07, 2016 | 7:30 AM
      Keynote Speaker: Challenges towards a Universal Influenza Virus Vaccine
      Keynote Speaker: Challenges towards a Universal Influenza Virus...
      Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality.  The present modalities and va...
      Speaker: Peter Palese, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      3
      SEP 07, 2016 | 6:00 AM
      Invisible Influence: How the indoor microbiome influences health
      Invisible Influence: How the indoor microbiome influences health
      The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
      Speaker: Jack Gilbert, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      2
      AUG 30, 2016 | 8:00 AM
      Human pluripotent stem cells for the study of enteric neuropathies
      Human pluripotent stem cells for the study of enteric neuropathies
      The human enteric nervous system (ENS) is derived from the neural crest and represents a complex network of ~500 million neurons with dozens of distinct neurotransmitter and hormone subtypes ...
      Speaker: Faranak Fattahi, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      AUG 30, 2016 | 8:00 AM
      Delivery solutions for robust CRISPR-based genomic editing in stem cells for disease model generation
      Delivery solutions for robust CRISPR-based genomic editing in...
      Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
      Speaker: Nektaria Andronikou
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      0
      AUG 30, 2016 | 8:00 AM
      From urine to the study of metabolic disease - A patient-driven strategy to decipher PCSK9 roles and functions.
      From urine to the study of metabolic disease - A patient-driven...
      In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
      Speaker: Karim Si-Tayeb, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      AUG 30, 2016 | 8:00 AM
      Transplanted human stem cell-derived interneuron precursors mitigate mouse bladder dysfunction and central neuropathic pain after spinal cord injury
      Transplanted human stem cell-derived interneuron precursors mitigate...
      Neuropathic pain and bladder dysfunction represent significant quality of life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to...
      Speaker: Cory Nicholas, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
    FEB 08, 2017 | 10:30 AM
    Biosecurity, Reproductive and Social Management of Cat Research Colonies
    Biosecurity, Reproductive and Social Management of Cat Research...
    DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
    Speaker: James Kehler VMD, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 08, 2017 | 10:30 AM
    Obtaining non-invasive readouts and early safety signals from rodent models
    Obtaining non-invasive readouts and early safety signals from...
    DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
    FEB 08, 2017 | 9:00 AM
    Evaluating the Effectiveness of Training  for Animal Care and Use Personnel
    Evaluating the Effectiveness of Training for Animal Care and...
    DATE: February 8, 2017TIME: 9:00am PT, Noon ETTraining programs for animal care and use personnel are integral to both animal welfare and quality research outcomes. There are a variety...
    Speaker: Melissa Dyson MS, DVM, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 08, 2017 | 6:00 AM
    Impact of Two Formulations of Buprenorphine on Postsurgical Condition in Mice
    Impact of Two Formulations of Buprenorphine on Postsurgical Condition...
    DATE: February 8, 2017TIME: 6:00am PT, 9:00 ETSeveral regulatory bodies require that animals used in biomedical and behavioral research exposed to procedures that may cause more th...
    Speaker: Nicole Herndon, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    7
    DEC 14, 2016 | 7:30 AM
    Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
    Advances in modeling human diseases using induced pluripotent...
    DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
    Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    7 1
     
     
  • DEC 01, 2016 | 8:00 AM
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
    DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
    Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
    Sponsored By: Revvity
    3
    NOV 17, 2016 | 7:00 AM
    Using patient-derived iPSCs to model and treat inherited retinal degenerative blindness
    Using patient-derived iPSCs to model and treat inherited retinal...
    Inherited retinal degenerative disorders such as retinitis pigmentosa are characterized by death of the light sensing photoreceptive neurons of the outer retina. Like the rest of the CNS, the...
    Speaker: KEYNOTE: Budd Tucker, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    6
    NOV 17, 2016 | 3:00 AM
    Genetic variability of ps-iPSC and related blood and fibroblasts - somatic mutations
    Genetic variability of ps-iPSC and related blood and fibroblasts...
    The generation of induced pluripotent stem cells (iPSCs) from adult easily accessible somatic tissues was introduced ten years ago. This technology has revolutionized our opportunities to stu...
    Speaker: KEYNOTE: Silke Rickert-Sperling, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    8 1
    NOV 16, 2016 | 4:00 PM
    Evolving your media system for modern stem cell applications
    Evolving your media system for modern stem cell applications
    Culture systems for pluripotent stem cell (PSC) expansion enable generation of a nearly unlimited pool of cells for downstream differentiation, disease modeling, drug discovery, and therapeut...
    Speaker: Rhonda Newman, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
    NOV 15, 2016 | 9:00 AM
    Antigen-specific, poly-functional CD4+ T cells are required for vaccine-mediated protection in tularemia
    Antigen-specific, poly-functional CD4+ T cells are required for...
    DATE: November 15, 2016 TIME: 9:00 AM PT, 12:00 PM ET The virulent intracellular pathogen Francisella tularensis subsp. tularensis (Ftt) causes an acute, lethal diseas...
    Speaker: Lydia Roberts, PhD
    Sponsored By: Miltenyi Biotec, Miltenyi Biotec
    3
     
     
  • NOV 10, 2016 | 9:00 AM
    CellSimpleâ„¢ Cell Analyzer: Delivering Convenience, Versatility and Efficiency for Your Application Workflows
    CellSimpleâ„¢ Cell Analyzer: Delivering Convenience, Versatility...
    DATE:  November 10, 2016 TIME:  9:00am PT, Noon ET The CellSimple™ Cell Analyzer enables quick and easy research assays, including functional cell-based assays, cell-model...
    Speaker: Jonah Riddell, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    2
    NOV 09, 2016 | 8:00 AM
    ProEnkephalin:(PENK).  New Biomarker and Novel Window to Kidney Function: Emerging new data of ProEnkephalin in Clinical Populations
    ProEnkephalin:(PENK). New Biomarker and Novel Window to Kidney...
    DATE:  November 9, 2016 TIME:  8:00am PT, 11:00am ET This talk will characterize the current clinical and laboratory standards for determining risk for chronic renal dysfunction...
    Speaker: Ravindra Mehta, MD , Alan Maisel, M.D. , Olle Melander, MD, PhD
    Sponsored By: Sphingotec LLC, Sphingotec LLC
    3
    NOV 03, 2016 | 12:00 PM
    Point of Care Testing - Why Knowing Now Matters in the Emergency Department
    Point of Care Testing - Why Knowing Now Matters in the Emergency...
    There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes.  There is an association between waiting times and short term mo...
    Speaker: Ellis Jacobs, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    0
    NOV 02, 2016 | 10:30 AM
    Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
    Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
    Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
    Speaker: Sebastiano Gattoni-Celli, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    OCT 18, 2016 | 1:00 PM
    The Role of 3D Culture Methods in Retaining Native Biological Properties of Translational In Vitro Models
    The Role of 3D Culture Methods in Retaining Native Biological...
    Cell Sciences Innovation, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ USA In vitro translational models play a critical role in the drug discovery process because t...
    Speaker: Richard Visconti, PhD
    Presented at: SyncD³ - Where drug discovery & development meet
    0
     
     
  • OCT 18, 2016 | 1:00 PM
    Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative Medicine Models of Brain Diseases
    Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative...
    Induced pluripotent stem cells derived from patient cells have emerged as complementary tools to study human neurological disorders.  Neurxstem Inc has generated human iPSC-derived synth...
    Speaker: Rene Anand, PhD
    Presented at: SyncD³ - Where drug discovery & development meet
    0
    OCT 18, 2016 | 9:00 AM
    Genome Editing of Human Pluripotent Stem Cells to Generate Human Cellular Disease Models
    Genome Editing of Human Pluripotent Stem Cells to Generate Human...
    ...
    Speaker: Kiran Musunuru, MD, PhD, MPH
    Presented at: SyncD³ - Where drug discovery & development meet
    0
    SEP 08, 2016 | 12:00 PM
    Plant Viruses: Everywhere and Often Mutualistic
    Plant Viruses: Everywhere and Often Mutualistic
     Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
    Speaker: Marilyn Roossinck, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    4
    SEP 07, 2016 | 7:30 AM
    Keynote Speaker: Challenges towards a Universal Influenza Virus Vaccine
    Keynote Speaker: Challenges towards a Universal Influenza Virus...
    Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality.  The present modalities and va...
    Speaker: Peter Palese, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    3
    SEP 07, 2016 | 6:00 AM
    Invisible Influence: How the indoor microbiome influences health
    Invisible Influence: How the indoor microbiome influences health
    The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
    Speaker: Jack Gilbert, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    2
     
     
  • AUG 30, 2016 | 8:00 AM
    Human pluripotent stem cells for the study of enteric neuropathies
    Human pluripotent stem cells for the study of enteric neuropathies
    The human enteric nervous system (ENS) is derived from the neural crest and represents a complex network of ~500 million neurons with dozens of distinct neurotransmitter and hormone subtypes ...
    Speaker: Faranak Fattahi, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    AUG 30, 2016 | 8:00 AM
    Delivery solutions for robust CRISPR-based genomic editing in stem cells for disease model generation
    Delivery solutions for robust CRISPR-based genomic editing in...
    Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
    Speaker: Nektaria Andronikou
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    0
    AUG 30, 2016 | 8:00 AM
    From urine to the study of metabolic disease - A patient-driven strategy to decipher PCSK9 roles and functions.
    From urine to the study of metabolic disease - A patient-driven...
    In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
    Speaker: Karim Si-Tayeb, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    AUG 30, 2016 | 8:00 AM
    Transplanted human stem cell-derived interneuron precursors mitigate mouse bladder dysfunction and central neuropathic pain after spinal cord injury
    Transplanted human stem cell-derived interneuron precursors mitigate...
    Neuropathic pain and bladder dysfunction represent significant quality of life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to...
    Speaker: Cory Nicholas, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
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