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    Drug Metabolism

    Drug metabolism is the term used to portray the biotransformation of drug substances in the body so they can be killed all the more without any problem. Most of metabolic cycles that include drugs happen in the liver, as the chemicals that encourage the responses are concentrated there.

    Webinars

    • SEP 26, 2018 | 12:00 PM
      3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
      3D Cell Cultures and Tissue Clearing: A High Content Confocal...
      With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
      Speaker: Michael Johnson, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      2
      SEP 17, 2018 | 8:00 PM
      WEBINAR: High Throughput Production of Autoantigens for Rapid Detection of Multiple Autoimmune Diseases
      WEBINAR: High Throughput Production of Autoantigens for Rapid...
      Current methods for in vitro diagnosis of autoimmune diseases (ADs) are mainly based on the detection of circulating autoantibodies using specific AD autoantigens. A high-quality recombinant...
      Speaker: Aimin Xu, PhD
      Presented at: 3rd Annual 7 Steps of Protein Virtual Event
      1
      SEP 13, 2018 | 1:30 PM
      Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
      Mechanisms of Antimicrobial Bioconversion by Environmental and...
      The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
      Speaker: Terence Crofts, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 05, 2018 | 8:00 AM
      A New Paradigm for Buprenorphine Testing
      A New Paradigm for Buprenorphine Testing
      DATE: September 5, 2018TIME: 8:00AM PDTA New Paradigm for Buprenorphine TestingBuprenorphine (BUP) is a partial mu-agonist synthetic opioid, an important drug for treating opio...
      Speaker: Judy Stone, MT(ASCP), Ph.D.,DABCC
      7 1
      AUG 30, 2018 | 8:00 AM
      Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
      Early disease detection performing NMR - Understanding how a better...
      DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
      Speaker: Elaine Holmes , Claudio Luchinat
      Sponsored By: Bruker Microbiology & Diagnostics
      6 2
      AUG 30, 2018 | 1:00 AM
      Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
      Early disease detection performing NMR - Understanding how a better...
      DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
      Speaker: Elaine Holmes , Claudio Luchinat
      Sponsored By: Bruker Microbiology & Diagnostics
      5 2
      JUN 20, 2018 | 10:30 AM
      A Pharmacogenomic Approach to Medical Cannabis
      A Pharmacogenomic Approach to Medical Cannabis
      The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
      Speaker: Jahan Marcu, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 05, 2018 | 6:30 AM
      Handling of viscous liquids - Basics, Techniques and Tricks
      Handling of viscous liquids - Basics, Techniques and Tricks
      DATE: June 5, 2018TIME: 06:30AM PDT, 3:30PM CEST Viscous liquids are a challenge in every lab that deals with them. Depending on how viscous a liquid is, pipetting is either...
      Speaker: Hanae Henke, PhD
      Sponsored By: Eppendorf
      19 25
      MAY 31, 2018 | 1:30 PM
      Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
      Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
      The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
      Speaker: Sabeth Verpoorte, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      MAY 22, 2018 | 8:00 AM
      Drug development with nuclear receptor knockout and humanized rat models
      Drug development with nuclear receptor knockout and humanized...
      DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
      Speaker: Kevin Forbes, PhD , Andrew Brown, MS
      Sponsored By: Horizon Discovery
      5
      MAY 10, 2018 | 9:00 AM
      Multi-Omics Approach for Discovering Anti-Folate Drug Resistance Mechanisms in Triple-Negative Breast Cancer: Working Toward the Goal of Personalized Medicine
      Multi-Omics Approach for Discovering Anti-Folate Drug Resistance...
      Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments.  Metabolic reprograming is now recognized as a fundam...
      Speaker: Steven Gross, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: Agilent
      1
      MAR 28, 2018 | 7:30 AM
      Keynote Presentation: Treating with Cannabis
      Keynote Presentation: Treating with Cannabis
      Cannabis use, both recreational and as medicine is proliferating worldwide. It's reasonable to ask why people are using cannabis and who are appropriate candidates for cannabis therapy. T...
      Speaker: Jeff Hergenrather, MD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      4
      NOV 01, 2017 | 12:00 AM
      Reprogrammed stem cells to study psychedelic substances
      Reprogrammed stem cells to study psychedelic substances
      For more than four decades, restrictions on research with psychoactive drugs have slowed progress in understanding how such substances impact brain metabolism. Besides the historical restrict...
      Speaker: Stevens Rehen
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      SEP 27, 2017 | 12:00 PM
      CRISPR-Cas9 genome engineering: Experimental Design and Applications
      CRISPR-Cas9 genome engineering: Experimental Design and Applications
      The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
      Speaker: Danielle Folkard
      Presented at: Cell Biology Virtual Event Series 2017
      Sponsored By: Horizon Discovery
      2
      SEP 27, 2017 | 10:30 AM
      Combining Seahorse XF analysis with stable isotope tracing to reveal novel drug targets for metabolic and neurodegenerative disease
      Combining Seahorse XF analysis with stable isotope tracing to...
      To study cell metabolism, our laboratory has found it exceedingly informative to integrate Agilent Seahorse XF Analyzers with mass spectrometry-based measurements of metabolomics and stable i...
      Speaker: Ajit Divakaruni, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      Sponsored By: Agilent
      1
      JUL 25, 2017 | 9:00 AM
      WEBINAR: Functional Genomics and Drug Metabolism
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      7 1
      JUL 01, 2017 | 8:00 AM
      iPSC-derived neural cells for drug discovery of mitochondrial brain diseases
      iPSC-derived neural cells for drug discovery of mitochondrial...
      Mitochondrial defects represent a common pathogenetic mechanism associated with neurodegeneration. At the same time, mitochondrial DNA (mtDNA) mutations frequently cause neurological diseases...
      Speaker: Alessandro Prigione
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUN 13, 2017 | 9:00 AM
      WEBINAR: High content imaging and analysis for drug discovery: phenotypic assays, instrumentation and software
      WEBINAR: High content imaging and analysis for drug discovery:...
      EVENT DETAILS: DATE: June 13, 2017TIME: 9:00am PT, 12:00pm ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in...
      Speaker: Nicholas Dolman, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      3
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
      FEB 23, 2017 | 1:30 PM
      Mining Dense, Dynamic Personal Data Clouds to Enhance Health
      Mining Dense, Dynamic Personal Data Clouds to Enhance Health
      Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
      Speaker: Nathan Price, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      FEB 23, 2017 | 12:00 PM
      Recent progress in cellular medicine with an eye to precision medicine
      Recent progress in cellular medicine with an eye to precision...
      Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
      Speaker: Giacinto Scoles, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      2
      FEB 23, 2017 | 9:00 AM
      Metabolomics and its Role in Precision Medicine
      Metabolomics and its Role in Precision Medicine
      Although there have been enormous advances in gene sequencing, the results give massive amounts of data that only point to disease risk. Major health factors, including diet, lifestyle, envir...
      Speaker: John Ryals, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      FEB 23, 2017 | 7:30 AM
      KEYNOTE: Towards a new era of precision medicine in psychiatry: Using genetic algorithms to optimize medication outcome
      KEYNOTE: Towards a new era of precision medicine in psychiatry:...
      Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
      Speaker: Daniel Mueller, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      DEC 06, 2016 | 8:00 AM
      Pre-emptive genotyping for pharmacogenomic risk - establishing a benchmark
      Pre-emptive genotyping for pharmacogenomic risk - establishing...
      DATE: December 6, 2016 TIME: 8:00am PT, 11:00am ET Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality in health care. In the US alone, an est...
      Speaker: Ulrich Broeckel, MD
      Sponsored By: Affymetrix, Affymetrix
      6
    SEP 26, 2018 | 12:00 PM
    3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
    3D Cell Cultures and Tissue Clearing: A High Content Confocal...
    With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
    Speaker: Michael Johnson, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    2
    SEP 17, 2018 | 8:00 PM
    WEBINAR: High Throughput Production of Autoantigens for Rapid Detection of Multiple Autoimmune Diseases
    WEBINAR: High Throughput Production of Autoantigens for Rapid...
    Current methods for in vitro diagnosis of autoimmune diseases (ADs) are mainly based on the detection of circulating autoantibodies using specific AD autoantigens. A high-quality recombinant...
    Speaker: Aimin Xu, PhD
    Presented at: 3rd Annual 7 Steps of Protein Virtual Event
    1
    SEP 13, 2018 | 1:30 PM
    Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
    Mechanisms of Antimicrobial Bioconversion by Environmental and...
    The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
    Speaker: Terence Crofts, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 05, 2018 | 8:00 AM
    A New Paradigm for Buprenorphine Testing
    A New Paradigm for Buprenorphine Testing
    DATE: September 5, 2018TIME: 8:00AM PDTA New Paradigm for Buprenorphine TestingBuprenorphine (BUP) is a partial mu-agonist synthetic opioid, an important drug for treating opio...
    Speaker: Judy Stone, MT(ASCP), Ph.D.,DABCC
    7 1
    AUG 30, 2018 | 8:00 AM
    Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
    Early disease detection performing NMR - Understanding how a better...
    DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
    Speaker: Elaine Holmes , Claudio Luchinat
    Sponsored By: Bruker Microbiology & Diagnostics
    6 2
     
     
  • AUG 30, 2018 | 1:00 AM
    Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
    Early disease detection performing NMR - Understanding how a better...
    DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
    Speaker: Elaine Holmes , Claudio Luchinat
    Sponsored By: Bruker Microbiology & Diagnostics
    5 2
    JUN 20, 2018 | 10:30 AM
    A Pharmacogenomic Approach to Medical Cannabis
    A Pharmacogenomic Approach to Medical Cannabis
    The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
    Speaker: Jahan Marcu, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 05, 2018 | 6:30 AM
    Handling of viscous liquids - Basics, Techniques and Tricks
    Handling of viscous liquids - Basics, Techniques and Tricks
    DATE: June 5, 2018TIME: 06:30AM PDT, 3:30PM CEST Viscous liquids are a challenge in every lab that deals with them. Depending on how viscous a liquid is, pipetting is either...
    Speaker: Hanae Henke, PhD
    Sponsored By: Eppendorf
    19 25
    MAY 31, 2018 | 1:30 PM
    Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
    Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
    The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
    Speaker: Sabeth Verpoorte, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
    MAY 22, 2018 | 8:00 AM
    Drug development with nuclear receptor knockout and humanized rat models
    Drug development with nuclear receptor knockout and humanized...
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    Speaker: Kevin Forbes, PhD , Andrew Brown, MS
    Sponsored By: Horizon Discovery
    5
     
     
  • MAY 10, 2018 | 9:00 AM
    Multi-Omics Approach for Discovering Anti-Folate Drug Resistance Mechanisms in Triple-Negative Breast Cancer: Working Toward the Goal of Personalized Medicine
    Multi-Omics Approach for Discovering Anti-Folate Drug Resistance...
    Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments.  Metabolic reprograming is now recognized as a fundam...
    Speaker: Steven Gross, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: Agilent
    1
    MAR 28, 2018 | 7:30 AM
    Keynote Presentation: Treating with Cannabis
    Keynote Presentation: Treating with Cannabis
    Cannabis use, both recreational and as medicine is proliferating worldwide. It's reasonable to ask why people are using cannabis and who are appropriate candidates for cannabis therapy. T...
    Speaker: Jeff Hergenrather, MD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    4
    NOV 01, 2017 | 12:00 AM
    Reprogrammed stem cells to study psychedelic substances
    Reprogrammed stem cells to study psychedelic substances
    For more than four decades, restrictions on research with psychoactive drugs have slowed progress in understanding how such substances impact brain metabolism. Besides the historical restrict...
    Speaker: Stevens Rehen
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    SEP 27, 2017 | 12:00 PM
    CRISPR-Cas9 genome engineering: Experimental Design and Applications
    CRISPR-Cas9 genome engineering: Experimental Design and Applications
    The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
    Speaker: Danielle Folkard
    Presented at: Cell Biology Virtual Event Series 2017
    Sponsored By: Horizon Discovery
    2
    SEP 27, 2017 | 10:30 AM
    Combining Seahorse XF analysis with stable isotope tracing to reveal novel drug targets for metabolic and neurodegenerative disease
    Combining Seahorse XF analysis with stable isotope tracing to...
    To study cell metabolism, our laboratory has found it exceedingly informative to integrate Agilent Seahorse XF Analyzers with mass spectrometry-based measurements of metabolomics and stable i...
    Speaker: Ajit Divakaruni, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    Sponsored By: Agilent
    1
     
     
  • JUL 25, 2017 | 9:00 AM
    WEBINAR: Functional Genomics and Drug Metabolism
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
    7 1
    JUL 01, 2017 | 8:00 AM
    iPSC-derived neural cells for drug discovery of mitochondrial brain diseases
    iPSC-derived neural cells for drug discovery of mitochondrial...
    Mitochondrial defects represent a common pathogenetic mechanism associated with neurodegeneration. At the same time, mitochondrial DNA (mtDNA) mutations frequently cause neurological diseases...
    Speaker: Alessandro Prigione
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUN 13, 2017 | 9:00 AM
    WEBINAR: High content imaging and analysis for drug discovery: phenotypic assays, instrumentation and software
    WEBINAR: High content imaging and analysis for drug discovery:...
    EVENT DETAILS: DATE: June 13, 2017TIME: 9:00am PT, 12:00pm ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in...
    Speaker: Nicholas Dolman, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    3
    MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
    FEB 23, 2017 | 1:30 PM
    Mining Dense, Dynamic Personal Data Clouds to Enhance Health
    Mining Dense, Dynamic Personal Data Clouds to Enhance Health
    Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
    Speaker: Nathan Price, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
     
     
  • FEB 23, 2017 | 12:00 PM
    Recent progress in cellular medicine with an eye to precision medicine
    Recent progress in cellular medicine with an eye to precision...
    Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
    Speaker: Giacinto Scoles, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    2
    FEB 23, 2017 | 9:00 AM
    Metabolomics and its Role in Precision Medicine
    Metabolomics and its Role in Precision Medicine
    Although there have been enormous advances in gene sequencing, the results give massive amounts of data that only point to disease risk. Major health factors, including diet, lifestyle, envir...
    Speaker: John Ryals, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
    FEB 23, 2017 | 7:30 AM
    KEYNOTE: Towards a new era of precision medicine in psychiatry: Using genetic algorithms to optimize medication outcome
    KEYNOTE: Towards a new era of precision medicine in psychiatry:...
    Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
    Speaker: Daniel Mueller, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
    DEC 06, 2016 | 8:00 AM
    Pre-emptive genotyping for pharmacogenomic risk - establishing a benchmark
    Pre-emptive genotyping for pharmacogenomic risk - establishing...
    DATE: December 6, 2016 TIME: 8:00am PT, 11:00am ET Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality in health care. In the US alone, an est...
    Speaker: Ulrich Broeckel, MD
    Sponsored By: Affymetrix, Affymetrix
    6
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