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    Gene Expression

    Gene Expression: the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA. The process of gene expression is used by all known life-eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses-to generate the macromolecular machinery for life.

    Webinars

    • NOV 16, 2020 | 8:00 AM
      Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
      Targeted single-cell RNA sequencing enables genome-scale CRISPR...
      Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
      Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
      Sponsored By: Illumina
      11
      November 13, 2020 4:00 PM PST | November 14, 2020 8:00 AM SGT
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
      Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
      Speaker: Srabani Bhaumik, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      November 12, 2020 9:00 AM PST | 4:00 PM GMT
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
      Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
      Speaker: Srabani Bhaumik, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 10, 2020 | 9:00 AM
      Fast and reliable Gene Synthesis for optimized protein expression
      Fast and reliable Gene Synthesis for optimized protein expression
      DATE: November 10, 2020 TIME: 9:00am PT, 12am ET Gene Synthesis ensures fast access to nearly any DNA sequence, regardless its origin or complexity. Its reliability, flexibility and fast tur...
      Speaker: Claudia Chiocchini
      Sponsored By: Thermo Fisher Scientific
      19
      NOV 10, 2020 | 7:00 AM
      Move Forward with Automation
      Move Forward with Automation
      DATE: November 10, 2020 TIME: 7:00am PDT, 10:00am EDT Automation can provide tremendous benefits such as increased pipetting precision and accuracy, productivity, and throughput. Numerous wo...
      Speaker: Paulina Kocjan , Kirk Mantione, PhD
      Sponsored By: Eppendorf
      15
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      OCT 29, 2020 | 8:00 AM
      Cell types to targets: Single cell RNA-sequencing for drug discovery
      Cell types to targets: Single cell RNA-sequencing for drug discovery
      Date: October 29, 2020 Time: 8:00am (PDT), 11:00am (EDT) What cell types cause and perpetuate disease? For many diseases, scientists only have guesses to this critical question. Single cell...
      Speaker: Sarah Middleton, PhD
      Sponsored By: 10x Genomics
      10 2
      OCT 27, 2020 | 8:00 AM
      Lyophilization-Changing the Game for Molecular Diagnostics
      Lyophilization-Changing the Game for Molecular Diagnostics
      DATE: October 27th, 2020 TIME: 8:00am PT Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic c...
      Speaker: Jerome Cabeau, MSc
      Sponsored By: Thermo Fisher Scientific
      11 2
      OCT 08, 2020 | 3:00 PM
      Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
      Reducing biological variance in tumor-antigen expression to standardize...
      The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
      Speaker: Benjamin Borgo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      OCT 08, 2020 | 12:00 PM
      ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
      ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
      Antibodies have become one of the most important tools in life science research, allowing the detection, quantitation, and determination of changes in proteins and other molecules with respe...
      Speaker: Wayne Speckmann, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 08, 2020 | 7:30 AM
      Keynote Presentation: RNA Splicing and Ancestry-related Molecular Targets in Precision Oncology and Cancer Disparities
      Keynote Presentation: RNA Splicing and Ancestry-related Molecular...
      Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
      Speaker: Steven R. Patierno, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      OCT 08, 2020 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      33 5
      OCT 08, 2020 | 6:00 AM
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
      Speaker: Christian Regenbrecht, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Luminex - A DiaSorin Company
      1
      OCT 08, 2020 | 12:00 AM
      Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
      Transcriptome analysis of breast cancer clinical specimens with...
      Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
      Speaker: Masahito Kawazu, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 07, 2020 | 10:30 AM
      Immune correlates of TP53 mutational status in acute myeloid leukemia
      Immune correlates of TP53 mutational status in acute myeloid leukemia
      Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
      Speaker: Dr. Sergio Rutella
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      OCT 07, 2020 | 12:00 AM
      Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of Futuristic Therapies
      Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of...
      Immune therapy approaches are being used in many different solid cancers today including clear cell renal carcinoma (mccRCC) and metastatic prostate adenocarcinoma. Over the past few years i...
      Speaker: Benjamin Maughan, MD, PharmD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      SEP 30, 2020 | 1:30 PM
      Harnessing novel CRISPR systems for genome engineering
      Harnessing novel CRISPR systems for genome engineering
      RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 30, 2020 | 12:00 PM
      Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
      Efficient Generation of Gene-edited Mouse Models and Cell Lines...
      The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
      Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      4
      SEP 30, 2020 | 10:30 AM
      Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
      Straightforward CRISPR knockout: Leveraging predesigned synthetic...
      CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
      Speaker: James Goldmeyer, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Horizon Discovery
      3 1
      SEP 30, 2020 | 9:00 AM
      Massively parallel microbial genome engineering using the Onyxâ„¢ Platform
      Massively parallel microbial genome engineering using the Onyxâ„¢...
      While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, editing efficiency, types of modifications available, an...
      Speaker: Nandini Krishnamurthy, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Inscripta
      2
      SEP 30, 2020 | 7:30 AM
      Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
      Keynote Presentation: Functionalizing Genome Editing Techniques...
      Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
      Speaker: Shondra Miller, PhD/Director
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Integrated DNA Technologies (IDT)
      2
    NOV 16, 2020 | 8:00 AM
    Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
    Targeted single-cell RNA sequencing enables genome-scale CRISPR...
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
    Sponsored By: Illumina
    11
    November 13, 2020 4:00 PM PST | November 14, 2020 8:00 AM SGT
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
    Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
    Speaker: Srabani Bhaumik, PhD
    Presented at: DISCOVERY Global User Symposium
    1
    November 12, 2020 9:00 AM PST | 4:00 PM GMT
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
    Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
    Speaker: Srabani Bhaumik, PhD
    Presented at: DISCOVERY Global User Symposium
    1
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 10, 2020 | 9:00 AM
    Fast and reliable Gene Synthesis for optimized protein expression
    Fast and reliable Gene Synthesis for optimized protein expression
    DATE: November 10, 2020 TIME: 9:00am PT, 12am ET Gene Synthesis ensures fast access to nearly any DNA sequence, regardless its origin or complexity. Its reliability, flexibility and fast tur...
    Speaker: Claudia Chiocchini
    Sponsored By: Thermo Fisher Scientific
    19
     
     
  • NOV 10, 2020 | 7:00 AM
    Move Forward with Automation
    Move Forward with Automation
    DATE: November 10, 2020 TIME: 7:00am PDT, 10:00am EDT Automation can provide tremendous benefits such as increased pipetting precision and accuracy, productivity, and throughput. Numerous wo...
    Speaker: Paulina Kocjan , Kirk Mantione, PhD
    Sponsored By: Eppendorf
    15
    NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
    OCT 29, 2020 | 8:00 AM
    Cell types to targets: Single cell RNA-sequencing for drug discovery
    Cell types to targets: Single cell RNA-sequencing for drug discovery
    Date: October 29, 2020 Time: 8:00am (PDT), 11:00am (EDT) What cell types cause and perpetuate disease? For many diseases, scientists only have guesses to this critical question. Single cell...
    Speaker: Sarah Middleton, PhD
    Sponsored By: 10x Genomics
    10 2
    OCT 27, 2020 | 8:00 AM
    Lyophilization-Changing the Game for Molecular Diagnostics
    Lyophilization-Changing the Game for Molecular Diagnostics
    DATE: October 27th, 2020 TIME: 8:00am PT Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic c...
    Speaker: Jerome Cabeau, MSc
    Sponsored By: Thermo Fisher Scientific
    11 2
    OCT 08, 2020 | 3:00 PM
    Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
    Reducing biological variance in tumor-antigen expression to standardize...
    The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
    Speaker: Benjamin Borgo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
     
     
  • OCT 08, 2020 | 12:00 PM
    ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
    ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
    Antibodies have become one of the most important tools in life science research, allowing the detection, quantitation, and determination of changes in proteins and other molecules with respe...
    Speaker: Wayne Speckmann, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 08, 2020 | 7:30 AM
    Keynote Presentation: RNA Splicing and Ancestry-related Molecular Targets in Precision Oncology and Cancer Disparities
    Keynote Presentation: RNA Splicing and Ancestry-related Molecular...
    Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
    Speaker: Steven R. Patierno, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    OCT 08, 2020 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    33 5
    OCT 08, 2020 | 6:00 AM
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
    Speaker: Christian Regenbrecht, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Luminex - A DiaSorin Company
    1
     
     
  • OCT 08, 2020 | 12:00 AM
    Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
    Transcriptome analysis of breast cancer clinical specimens with...
    Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
    Speaker: Masahito Kawazu, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 07, 2020 | 10:30 AM
    Immune correlates of TP53 mutational status in acute myeloid leukemia
    Immune correlates of TP53 mutational status in acute myeloid leukemia
    Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
    Speaker: Dr. Sergio Rutella
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    OCT 07, 2020 | 12:00 AM
    Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of Futuristic Therapies
    Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of...
    Immune therapy approaches are being used in many different solid cancers today including clear cell renal carcinoma (mccRCC) and metastatic prostate adenocarcinoma. Over the past few years i...
    Speaker: Benjamin Maughan, MD, PharmD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    SEP 30, 2020 | 1:30 PM
    Harnessing novel CRISPR systems for genome engineering
    Harnessing novel CRISPR systems for genome engineering
    RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: CRISPR Virtual Event Series 2020
    4
    SEP 30, 2020 | 12:00 PM
    Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
    Efficient Generation of Gene-edited Mouse Models and Cell Lines...
    The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
    Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    4
     
     
  • SEP 30, 2020 | 10:30 AM
    Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
    Straightforward CRISPR knockout: Leveraging predesigned synthetic...
    CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
    Speaker: James Goldmeyer, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    3 1
    SEP 30, 2020 | 9:00 AM
    Massively parallel microbial genome engineering using the Onyxâ„¢ Platform
    Massively parallel microbial genome engineering using the Onyxâ„¢...
    While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, editing efficiency, types of modifications available, an...
    Speaker: Nandini Krishnamurthy, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Inscripta
    2
    SEP 30, 2020 | 7:30 AM
    Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
    Keynote Presentation: Functionalizing Genome Editing Techniques...
    Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
    Speaker: Shondra Miller, PhD/Director
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Integrated DNA Technologies (IDT)
    2
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