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    Pre-Clinical

    Pre-Clinical: relating to or denoting a stage preceding a clinical stage, in particular.

    Webinars

    • SEP 09, 2020 | 12:00 AM
      Bacterial Epigenomes: Technology, Pathogens and Microbiome
      Bacterial Epigenomes: Technology, Pathogens and Microbiome
      Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
      Speaker: Gang Fang
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 09, 2020 | 12:00 AM
      Understanding the role of virus-host interactions in tissue tropism of plant viruses
      Understanding the role of virus-host interactions in tissue tropism...
      To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
      Speaker: Svetlana Y. Folimonova
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 09, 2020 | 12:00 AM
      Fc gamma receptor activation during viral infections: a double-edged sword
      Fc gamma receptor activation during viral infections: a double-edged...
      Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
      Speaker: Raymond A. Alvarez, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Applications of Machine Learning to Predict Clinical Provenance of Haemophilus influenzae
      Applications of Machine Learning to Predict Clinical Provenance...
      Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
      Speaker: Joshua Earl, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Development of Respiratory Syncytial Virus and Universal Influenza Virus Vaccines Conformationally Stabilized by Targeted Dityrosine Crosslinking
      Development of Respiratory Syncytial Virus and Universal Influenza...
      While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
      Speaker: Mark A. Yondola, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Deep Learning by Analogy: Applying Text and Image Processing Techniques to Sequence Analysis
      Deep Learning by Analogy: Applying Text and Image Processing Techniques...
      Over the past five years there has been an explosion of research the deep learning field. Companies like Google, Facebook, and OpenAI have created neural networks that are significantly more...
      Speaker: Will Dampier, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
      Recombination, lineage-specific mutations and the emergence of...
      The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
      Speaker: Ioan Filip, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Nanoparticle-based next-generation influenza vaccines
      Nanoparticle-based next-generation influenza vaccines
      Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
      Speaker: Masaru Kanekiyo, DVM, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
      Deep mutational scanning of SARS-CoV-2 receptor binding domain...
      The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
      Speaker: Tyler Starr, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 08, 2020 | 12:00 PM
      Keynote Presentation: Structure-based Vaccine Design for COVID-19 and other Respiratory Viruses
      Keynote Presentation: Structure-based Vaccine Design for COVID-19...
      While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
      Speaker: Barney S. Graham, MD, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 10:00 AM
      Keynote Presentation: Single-cell virus sequencing of influenza infections that trigger innate immunity
      Keynote Presentation: Single-cell virus sequencing of influenza...
      Influenza infections are initiated by just a handful of virions infecting a handful of cells, so it is important to understand what happens in single infected cells. I will describe work tha...
      Speaker: Jesse D. Bloom, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 08, 2020 | 9:00 AM
      Keynote Presentation: A Universal Influenza Virus Vaccine
      Keynote Presentation: A Universal Influenza Virus Vaccine
      Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
      Speaker: Peter Palese, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      3
      SEP 08, 2020 | 6:00 AM
      Digital PCR using QIAGEN's QIacuity system: an introduction
      Digital PCR using QIAGEN's QIacuity system: an introduction
      This webinar covers various fundamental aspects of performing a successful digital PCR (dPCR) assay on the QIAcuity instruments. An essential parameter to consider in designing a dPCR assay...
      Speaker: Andreas Missel, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 04, 2020 | 8:00 AM
      Incorporation and Automation of RNAscope Technology into your COVID-19 Viral Pathogenesis Research
      Incorporation and Automation of RNAscope Technology into your...
      Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
      Speaker: Jyoti Phatak-Sheldon , Andrea De Biase, M.S. , Damian Cockfield
      Sponsored By: Leica Biosystems, ACD - A Bio-Techne Brand
      14 8
      SEP 03, 2020 | 11:00 AM
      Filtered Fume Hoods: Expert insight on improving your lab's green initiative
      Filtered Fume Hoods: Expert insight on improving your lab's green...
      DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
      Speaker: Kasey Fulmer , Kenneth Crooks
      Sponsored By: Labconco
      11
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 25, 2020 | 8:00 AM
      How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
      How LV and AAV Transfection Platforms will Shape the Future of...
      DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
      Speaker: Leisha Kopp
      Sponsored By: Mirus
      18 2
      JUL 22, 2020 | 10:00 AM
      Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
      Molecular Diagnostic Solutions in a Pandemic: Planning for the...
      DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
      Speaker: Heba Mostafa, MD, PhD, D(ABMM)
      Sponsored By: GenMark Dx
      27 13
      JUL 08, 2020 | 8:00 AM
      Advancing Targeted Protein Degradation Research with Automated Western Blotting
      Advancing Targeted Protein Degradation Research with Automated...
      DATE: July 8, 2020 TIME: 8:00am PDT In this webinar, discover how targeted protein degradation is being used to drive drug discovery. Hosted by Gary Allenby, Chief Executive Officer of Aurel...
      Speaker: Dr. Gary Allenby
      Sponsored By: ACD - A Bio-Techne Brand
      18
      JUL 02, 2020 | 2:30 PM
      Polygenic Risk Score analysis for Alzheimer's disease risk
      Polygenic Risk Score analysis for Alzheimer's disease risk
      The utility of Polygenic Risk Scores (PRS) is gaining researchers' attention for identifying individual genetic risk and disease risk prediction in Alzheimer's Disease (AD) at both t...
      Speaker: Richard Pither, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUL 01, 2020 | 12:15 PM
      Simplify your journey of molecular profiling with single day NGS
      Simplify your journey of molecular profiling with single day NGS
      Learn about how the new Ion Torrent Genexus System is addressing key challenges to next-generation sequencing (NGS) implementation, like hands-on time, time-to-result, user expertise, and af...
      Speaker: Jon Sherlock, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 30, 2020 | 8:00 AM
      Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex Technology
      Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex...
      DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
      Speaker: Chifei Sun
      Sponsored By: Leica Biosystems
      19
      JUN 24, 2020 | 9:00 AM
      Advanced quantitative fluorescence microscopy to probe the molecular dynamics of viral entry.
      Advanced quantitative fluorescence microscopy to probe the molecular...
      DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
      Speaker: Luis Alvarez, Ph.D.
      Sponsored By: Leica Microsystems
      15 1
    SEP 09, 2020 | 12:00 AM
    Bacterial Epigenomes: Technology, Pathogens and Microbiome
    Bacterial Epigenomes: Technology, Pathogens and Microbiome
    Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
    Speaker: Gang Fang
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 09, 2020 | 12:00 AM
    Understanding the role of virus-host interactions in tissue tropism of plant viruses
    Understanding the role of virus-host interactions in tissue tropism...
    To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
    Speaker: Svetlana Y. Folimonova
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 09, 2020 | 12:00 AM
    Fc gamma receptor activation during viral infections: a double-edged sword
    Fc gamma receptor activation during viral infections: a double-edged...
    Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
    Speaker: Raymond A. Alvarez, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Applications of Machine Learning to Predict Clinical Provenance of Haemophilus influenzae
    Applications of Machine Learning to Predict Clinical Provenance...
    Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
    Speaker: Joshua Earl, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Development of Respiratory Syncytial Virus and Universal Influenza Virus Vaccines Conformationally Stabilized by Targeted Dityrosine Crosslinking
    Development of Respiratory Syncytial Virus and Universal Influenza...
    While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
    Speaker: Mark A. Yondola, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 08, 2020 | 11:00 PM
    Deep Learning by Analogy: Applying Text and Image Processing Techniques to Sequence Analysis
    Deep Learning by Analogy: Applying Text and Image Processing Techniques...
    Over the past five years there has been an explosion of research the deep learning field. Companies like Google, Facebook, and OpenAI have created neural networks that are significantly more...
    Speaker: Will Dampier, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
    Recombination, lineage-specific mutations and the emergence of...
    The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
    Speaker: Ioan Filip, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Nanoparticle-based next-generation influenza vaccines
    Nanoparticle-based next-generation influenza vaccines
    Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
    Speaker: Masaru Kanekiyo, DVM, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
    Deep mutational scanning of SARS-CoV-2 receptor binding domain...
    The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
    Speaker: Tyler Starr, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 08, 2020 | 12:00 PM
    Keynote Presentation: Structure-based Vaccine Design for COVID-19 and other Respiratory Viruses
    Keynote Presentation: Structure-based Vaccine Design for COVID-19...
    While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
    Speaker: Barney S. Graham, MD, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 08, 2020 | 10:00 AM
    Keynote Presentation: Single-cell virus sequencing of influenza infections that trigger innate immunity
    Keynote Presentation: Single-cell virus sequencing of influenza...
    Influenza infections are initiated by just a handful of virions infecting a handful of cells, so it is important to understand what happens in single infected cells. I will describe work tha...
    Speaker: Jesse D. Bloom, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 08, 2020 | 9:00 AM
    Keynote Presentation: A Universal Influenza Virus Vaccine
    Keynote Presentation: A Universal Influenza Virus Vaccine
    Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
    Speaker: Peter Palese, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
    SEP 08, 2020 | 6:00 AM
    Digital PCR using QIAGEN's QIacuity system: an introduction
    Digital PCR using QIAGEN's QIacuity system: an introduction
    This webinar covers various fundamental aspects of performing a successful digital PCR (dPCR) assay on the QIAcuity instruments. An essential parameter to consider in designing a dPCR assay...
    Speaker: Andreas Missel, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    SEP 04, 2020 | 8:00 AM
    Incorporation and Automation of RNAscope Technology into your COVID-19 Viral Pathogenesis Research
    Incorporation and Automation of RNAscope Technology into your...
    Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
    Speaker: Jyoti Phatak-Sheldon , Andrea De Biase, M.S. , Damian Cockfield
    Sponsored By: Leica Biosystems, ACD - A Bio-Techne Brand
    14 8
    SEP 03, 2020 | 11:00 AM
    Filtered Fume Hoods: Expert insight on improving your lab's green initiative
    Filtered Fume Hoods: Expert insight on improving your lab's green...
    DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
    Speaker: Kasey Fulmer , Kenneth Crooks
    Sponsored By: Labconco
    11
     
     
  • SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    AUG 25, 2020 | 8:00 AM
    How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
    How LV and AAV Transfection Platforms will Shape the Future of...
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    Speaker: Leisha Kopp
    Sponsored By: Mirus
    18 2
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
    JUL 08, 2020 | 8:00 AM
    Advancing Targeted Protein Degradation Research with Automated Western Blotting
    Advancing Targeted Protein Degradation Research with Automated...
    DATE: July 8, 2020 TIME: 8:00am PDT In this webinar, discover how targeted protein degradation is being used to drive drug discovery. Hosted by Gary Allenby, Chief Executive Officer of Aurel...
    Speaker: Dr. Gary Allenby
    Sponsored By: ACD - A Bio-Techne Brand
    18
    JUL 02, 2020 | 2:30 PM
    Polygenic Risk Score analysis for Alzheimer's disease risk
    Polygenic Risk Score analysis for Alzheimer's disease risk
    The utility of Polygenic Risk Scores (PRS) is gaining researchers' attention for identifying individual genetic risk and disease risk prediction in Alzheimer's Disease (AD) at both t...
    Speaker: Richard Pither, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
     
     
  • JUL 01, 2020 | 12:15 PM
    Simplify your journey of molecular profiling with single day NGS
    Simplify your journey of molecular profiling with single day NGS
    Learn about how the new Ion Torrent Genexus System is addressing key challenges to next-generation sequencing (NGS) implementation, like hands-on time, time-to-result, user expertise, and af...
    Speaker: Jon Sherlock, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 30, 2020 | 8:00 AM
    Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex Technology
    Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex...
    DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
    Speaker: Chifei Sun
    Sponsored By: Leica Biosystems
    19
    JUN 24, 2020 | 9:00 AM
    Advanced quantitative fluorescence microscopy to probe the molecular dynamics of viral entry.
    Advanced quantitative fluorescence microscopy to probe the molecular...
    DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
    Speaker: Luis Alvarez, Ph.D.
    Sponsored By: Leica Microsystems
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