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    Cell Based Assays

    Cell Based Assays: this form of assay is one that looks at the effect of a given treatment on live cells. They measure proliferation, viability and cytotoxicity. Commonly used to monitor the response and health of cells in culture after treatment with various stimuli.

    Webinars

    • SEP 11, 2018 | 7:00 AM
      Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
      Answering the Challenges of Cell Viability and Reporter Gene Assays...
      DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
      Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
      Sponsored By: Revvity
      5
      AUG 09, 2018 | 7:00 AM
      3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
      3D Cell Cultures and Tissue Clearing: A High Content Confocal...
      With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
      Speaker: Michael Johnson, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      JUN 28, 2018 | 8:00 AM
      Isolation of immune cells Straight From whole blood, buffy coat, LRSC, and Leukopak without density gradients
      Isolation of immune cells Straight From whole blood, buffy coat,...
      DATE: June 28, 2018TIME: 8:00AM PDTEnrichment of leukocytes from blood products like buffy coat, leukocyte reduction chambers (LRSC) or leukapheresis material can be time consuming...
      Speaker: Zhong Yu, PhD , Gregory Winkels, MS
      Sponsored By: Miltenyi Biotec
      13 2
      JUN 20, 2018 | 7:30 AM
      Keynote Presentation: Supporting Precision Medicine and Clinical Research at Scale - Challenges and Opportunities
      Keynote Presentation: Supporting Precision Medicine and Clinical...
      Precision medicine based on molecular profiling is moving from the realm of clinical utility studies towards standard of care. There remain, however, significant technological and implementat...
      Speaker: Niall Lennon, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      MAY 31, 2018 | 1:30 PM
      Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
      Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
      The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
      Speaker: Sabeth Verpoorte, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      MAY 31, 2018 | 12:00 PM
      Cas9-Based Genome Engineering
      Cas9-Based Genome Engineering
      I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
      Speaker: Alejandro Chavez, MD, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2
      MAY 31, 2018 | 10:30 AM
      Multi-Tissue Experiments in a Scalable and Automation-Compatible Format
      Multi-Tissue Experiments in a Scalable and Automation-Compatible...
      The next step towards more biomimetic in vitro models is the design of multi-organ devices, which allow for communication of different tissue types. Combining physiologically relevant organ m...
      Speaker: Olivier Frey, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      MAY 31, 2018 | 9:00 AM
      Automation of Live-Cell Metabolic Assays with the Seahorse XFe96 Analyzer and Bravo Automated Liquid Handling Platform
      Automation of Live-Cell Metabolic Assays with the Seahorse XFe96...
      Cell-based assays are more biologically relevant than biochemical assays yet significantly more scalable than in vivo experiments.  However, care must be taken in sample preparation to e...
      Speaker: Sarah Burroughs, PhD , Kenda Evans, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      Sponsored By: Agilent
      3
      MAY 30, 2018 | 10:30 AM
      Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
      Inhibitors of NSD2 Discovered by High-Throughput Screening with...
      NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
      Speaker: Nathan Coussens, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      MAY 30, 2018 | 9:00 AM
      Automation Meets Cell Separation
      Automation Meets Cell Separation
      In this webinar Automation Meets Cell Separation as we will discuss the benefits of automating cell isolation processes in laboratories of variable size and sample throughput, and go into det...
      Speaker: Lotta Raty
      Presented at: Lab Automation Virtual Event Series 2018
      Sponsored By: Miltenyi Biotec
      1
      MAY 30, 2018 | 6:00 AM
      Phenotypic Profiling for Improving Drug Discovery Productivity
      Phenotypic Profiling for Improving Drug Discovery Productivity
      The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
      Speaker: Ellen Berg, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2 1
      MAY 29, 2018 | 9:00 AM
      Dissecting the Tumor Microenvironment Part 2 - Tools for isolation and flow analysis
      Dissecting the Tumor Microenvironment Part 2 - Tools for isolation...
      Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
      Speaker: César Evaristo, PhD
      Sponsored By: Miltenyi Biotec
      7
      MAY 24, 2018 | 9:00 AM
      Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation and Flow Analysis
      Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation...
      Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
      Speaker: Olaf Hardt, PhD
      Sponsored By: Miltenyi Biotec
      8 2
      MAY 22, 2018 | 8:00 AM
      Drug development with nuclear receptor knockout and humanized rat models
      Drug development with nuclear receptor knockout and humanized...
      DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
      Speaker: Kevin Forbes, PhD , Andrew Brown, MS
      Sponsored By: Horizon Discovery
      5
      MAY 03, 2018 | 11:00 AM
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
      DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
      Speaker: Sisi Li
      Sponsored By: Covaris
      5 2
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      APR 06, 2018 | 9:00 AM
      Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
      Multiplex Immunofluorescence Profiling of Tumor Biopsies Using...
      DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
      Speaker: Helen Snyder, PhD , Marie-Louise Loupart, PhD
      Sponsored By: Leica Biosystems
      8
      MAR 28, 2018 | 10:00 AM
      Primary Cell Systems:  Offerings and Applications from basic biology and tissue modeling to compound screening
      Primary Cell Systems: Offerings and Applications from basic biology...
      DATE: March 28, 2018TIME: 10:00am PDT, 01:00pm EDTPrimary cells are derived from various tissues typically via dissection, enzymatic dissociation, and subsequent culture in media specif...
      Speaker: David Kuninger, PhD , Rhonda Newman, PhD
      Sponsored By: Thermo Fisher Scientific
      7 3
      MAR 22, 2018 | 8:00 AM
      Simple and effective tools for antibody-drug conjugate screening and characterization
      Simple and effective tools for antibody-drug conjugate screening...
      Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not i...
      Speaker: Chris Langsdorf
      Presented at: Protein and Cell Analysis Education Series
      4
      MAR 15, 2018 | 9:00 AM
      Multiplex Immunoassay Detection of Alzheimer's Disease Biomarkers in Cerebrospinal Fluid, Plasma, and Serum
      Multiplex Immunoassay Detection of Alzheimer's Disease Biomarkers...
      Monitoring protein biomarkers in cerebrospinal fluid (CSF) of patients with Alzheimer’s Disease (AD) has been highly beneficial to understanding disease progression.  While several...
      Speaker: Anthony Saporita, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      2
      MAR 14, 2018 | 10:30 AM
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
      CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
      Speaker: Jeremy Lehmann
      Presented at: Neuroscience Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      1
      FEB 28, 2018 | 12:00 AM
      Improved Neuronal Performance with the Gibco B-27 Plus Culture System
      Improved Neuronal Performance with the Gibco B-27 Plus Culture...
      TBD...
      Speaker: David Kuninger, PhD
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      FEB 27, 2018 | 8:00 AM
      WEBINAR: Flow Cytometric Approach to Probiotic Cell Counting and Analysis
      WEBINAR: Flow Cytometric Approach to Probiotic Cell Counting and...
      DATE: February 27, 2018TIME:  8:00AM PST, 11:00AM EST The complexity of the manufacturing process of probiotic supplements, along with increased demand and strict criteria f...
      Speaker: Dharlene Tundo
      Sponsored By: Beckman Coulter Life Sciences
      9 2
      FEB 21, 2018 | 10:30 AM
      Panel Discussion: Co-development of Drugs and Companion Diagnostics
      Panel Discussion: Co-development of Drugs and Companion Diagnostics
      The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
      Speaker: Annette Gilchrist, PhD , Martin Shaw , Thomas Webster, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
    SEP 11, 2018 | 7:00 AM
    Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
    Answering the Challenges of Cell Viability and Reporter Gene Assays...
    DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
    Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
    Sponsored By: Revvity
    5
    AUG 09, 2018 | 7:00 AM
    3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
    3D Cell Cultures and Tissue Clearing: A High Content Confocal...
    With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
    Speaker: Michael Johnson, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    JUN 28, 2018 | 8:00 AM
    Isolation of immune cells Straight From whole blood, buffy coat, LRSC, and Leukopak without density gradients
    Isolation of immune cells Straight From whole blood, buffy coat,...
    DATE: June 28, 2018TIME: 8:00AM PDTEnrichment of leukocytes from blood products like buffy coat, leukocyte reduction chambers (LRSC) or leukapheresis material can be time consuming...
    Speaker: Zhong Yu, PhD , Gregory Winkels, MS
    Sponsored By: Miltenyi Biotec
    13 2
    JUN 20, 2018 | 7:30 AM
    Keynote Presentation: Supporting Precision Medicine and Clinical Research at Scale - Challenges and Opportunities
    Keynote Presentation: Supporting Precision Medicine and Clinical...
    Precision medicine based on molecular profiling is moving from the realm of clinical utility studies towards standard of care. There remain, however, significant technological and implementat...
    Speaker: Niall Lennon, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    MAY 31, 2018 | 1:30 PM
    Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
    Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
    The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
    Speaker: Sabeth Verpoorte, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
     
     
  • MAY 31, 2018 | 12:00 PM
    Cas9-Based Genome Engineering
    Cas9-Based Genome Engineering
    I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
    Speaker: Alejandro Chavez, MD, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2
    MAY 31, 2018 | 10:30 AM
    Multi-Tissue Experiments in a Scalable and Automation-Compatible Format
    Multi-Tissue Experiments in a Scalable and Automation-Compatible...
    The next step towards more biomimetic in vitro models is the design of multi-organ devices, which allow for communication of different tissue types. Combining physiologically relevant organ m...
    Speaker: Olivier Frey, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
    MAY 31, 2018 | 9:00 AM
    Automation of Live-Cell Metabolic Assays with the Seahorse XFe96 Analyzer and Bravo Automated Liquid Handling Platform
    Automation of Live-Cell Metabolic Assays with the Seahorse XFe96...
    Cell-based assays are more biologically relevant than biochemical assays yet significantly more scalable than in vivo experiments.  However, care must be taken in sample preparation to e...
    Speaker: Sarah Burroughs, PhD , Kenda Evans, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    Sponsored By: Agilent
    3
    MAY 30, 2018 | 10:30 AM
    Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
    Inhibitors of NSD2 Discovered by High-Throughput Screening with...
    NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
    Speaker: Nathan Coussens, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
    MAY 30, 2018 | 9:00 AM
    Automation Meets Cell Separation
    Automation Meets Cell Separation
    In this webinar Automation Meets Cell Separation as we will discuss the benefits of automating cell isolation processes in laboratories of variable size and sample throughput, and go into det...
    Speaker: Lotta Raty
    Presented at: Lab Automation Virtual Event Series 2018
    Sponsored By: Miltenyi Biotec
    1
     
     
  • MAY 30, 2018 | 6:00 AM
    Phenotypic Profiling for Improving Drug Discovery Productivity
    Phenotypic Profiling for Improving Drug Discovery Productivity
    The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
    Speaker: Ellen Berg, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2 1
    MAY 29, 2018 | 9:00 AM
    Dissecting the Tumor Microenvironment Part 2 - Tools for isolation and flow analysis
    Dissecting the Tumor Microenvironment Part 2 - Tools for isolation...
    Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
    Speaker: César Evaristo, PhD
    Sponsored By: Miltenyi Biotec
    7
    MAY 24, 2018 | 9:00 AM
    Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation and Flow Analysis
    Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation...
    Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
    Speaker: Olaf Hardt, PhD
    Sponsored By: Miltenyi Biotec
    8 2
    MAY 22, 2018 | 8:00 AM
    Drug development with nuclear receptor knockout and humanized rat models
    Drug development with nuclear receptor knockout and humanized...
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    Speaker: Kevin Forbes, PhD , Andrew Brown, MS
    Sponsored By: Horizon Discovery
    5
    MAY 03, 2018 | 11:00 AM
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    Speaker: Sisi Li
    Sponsored By: Covaris
    5 2
     
     
  • APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    APR 06, 2018 | 9:00 AM
    Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
    Multiplex Immunofluorescence Profiling of Tumor Biopsies Using...
    DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
    Speaker: Helen Snyder, PhD , Marie-Louise Loupart, PhD
    Sponsored By: Leica Biosystems
    8
    MAR 28, 2018 | 10:00 AM
    Primary Cell Systems:  Offerings and Applications from basic biology and tissue modeling to compound screening
    Primary Cell Systems: Offerings and Applications from basic biology...
    DATE: March 28, 2018TIME: 10:00am PDT, 01:00pm EDTPrimary cells are derived from various tissues typically via dissection, enzymatic dissociation, and subsequent culture in media specif...
    Speaker: David Kuninger, PhD , Rhonda Newman, PhD
    Sponsored By: Thermo Fisher Scientific
    7 3
    MAR 22, 2018 | 8:00 AM
    Simple and effective tools for antibody-drug conjugate screening and characterization
    Simple and effective tools for antibody-drug conjugate screening...
    Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not i...
    Speaker: Chris Langsdorf
    Presented at: Protein and Cell Analysis Education Series
    4
    MAR 15, 2018 | 9:00 AM
    Multiplex Immunoassay Detection of Alzheimer's Disease Biomarkers in Cerebrospinal Fluid, Plasma, and Serum
    Multiplex Immunoassay Detection of Alzheimer's Disease Biomarkers...
    Monitoring protein biomarkers in cerebrospinal fluid (CSF) of patients with Alzheimer’s Disease (AD) has been highly beneficial to understanding disease progression.  While several...
    Speaker: Anthony Saporita, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    2
     
     
  • MAR 14, 2018 | 10:30 AM
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
    CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
    Speaker: Jeremy Lehmann
    Presented at: Neuroscience Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    1
    FEB 28, 2018 | 12:00 AM
    Improved Neuronal Performance with the Gibco B-27 Plus Culture System
    Improved Neuronal Performance with the Gibco B-27 Plus Culture...
    TBD...
    Speaker: David Kuninger, PhD
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    FEB 27, 2018 | 8:00 AM
    WEBINAR: Flow Cytometric Approach to Probiotic Cell Counting and Analysis
    WEBINAR: Flow Cytometric Approach to Probiotic Cell Counting and...
    DATE: February 27, 2018TIME:  8:00AM PST, 11:00AM EST The complexity of the manufacturing process of probiotic supplements, along with increased demand and strict criteria f...
    Speaker: Dharlene Tundo
    Sponsored By: Beckman Coulter Life Sciences
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    FEB 21, 2018 | 10:30 AM
    Panel Discussion: Co-development of Drugs and Companion Diagnostics
    Panel Discussion: Co-development of Drugs and Companion Diagnostics
    The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
    Speaker: Annette Gilchrist, PhD , Martin Shaw , Thomas Webster, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
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