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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • SEP 18, 2018 | 9:00 AM
      Validation of clinical LC-MS/MS methods: What you need to know
      Validation of clinical LC-MS/MS methods: What you need to know
      DATE: September 18, 2018TIME: 9:00AM PDTLC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over m...
      Speaker: Deborah French, Ph,D., DABCC (CC, TC), FAACC
      12 1
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      SEP 12, 2018 | 8:00 AM
      Advancing precision immunotherapy through next generation sequencing of T-cell receptors: Part II
      Advancing precision immunotherapy through next generation sequencing...
      DATE:  September 12, 2018 TIME:  08:00am PDT, 11:00am EDT In the last presentation of this webinar series, we will continue our discussions on recent advancements i...
      Speaker: Timothy Looney, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      9
      SEP 11, 2018 | 7:00 AM
      Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
      Answering the Challenges of Cell Viability and Reporter Gene Assays...
      DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
      Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
      Sponsored By: Revvity
      5
      AUG 16, 2018 | 8:00 AM
      Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
      Advancing precision immunotherapy through next-generation sequencing...
      DATE: August, 16, 2018TIME: 08:00AM PDTThis webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards...
      Speaker: Timothy Looney, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      7
      AUG 09, 2018 | 7:00 AM
      3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
      3D Cell Cultures and Tissue Clearing: A High Content Confocal...
      With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
      Speaker: Michael Johnson, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      AUG 07, 2018 | 8:00 AM
      Using Reference Standards to Validate your NGS Oncology Workflow
      Using Reference Standards to Validate your NGS Oncology Workflow
      DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
      Speaker: Hannah Child, PhD
      Sponsored By: Horizon Discovery
      10 1
      JUL 19, 2018 | 9:00 AM
      Investigating the role of microRNAs in pancreatic cancer progression
      Investigating the role of microRNAs in pancreatic cancer progression
      DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
      Speaker: Silvia Ottaviani, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 5
      JUL 12, 2018 | 8:00 AM
      Little and Large - Using the flexibility of the MoFlo Astrios from sorting bacteria, through the more classic blood and human cells through to plant protoplasts!
      Little and Large - Using the flexibility of the MoFlo Astrios...
      Our MoFlo Astrios serves or multidisciplinary Department of Biology through our open access Bioscience Technology Imaging and Cytometry Core Lab at the University of York. As a core instrumen...
      Speaker: Dr. Karen Hogg , Professor Peter O'Toole
      Sponsored By: Beckman Coulter Life Sciences
      4
      JUN 29, 2018 | 9:00 AM
      Diet and gene interactions in the control of central cell metabolism
      Diet and gene interactions in the control of central cell metabolism
      DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
      Speaker: Sophie Prosolek
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 2
      JUN 28, 2018 | 8:00 AM
      Isolation of immune cells Straight From whole blood, buffy coat, LRSC, and Leukopak without density gradients
      Isolation of immune cells Straight From whole blood, buffy coat,...
      DATE: June 28, 2018TIME: 8:00AM PDTEnrichment of leukocytes from blood products like buffy coat, leukocyte reduction chambers (LRSC) or leukapheresis material can be time consuming...
      Speaker: Zhong Yu, PhD , Gregory Winkels, MS
      Sponsored By: Miltenyi Biotec
      13 2
      JUN 27, 2018 | 8:00 AM
      Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize success
      Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize...
      DATE: June 27, 2018TIME: 08:00AM PDT CRISPR-Cas9 is a very versatile tool to discover more about your pathway or gene of interest. Its simplicity has led to an explosion in a...
      Speaker: Laura Carleton, PhD
      Sponsored By: Horizon Discovery
      13 1
      JUN 26, 2018 | 8:00 AM
      The need for sensitivity - The CytoFlex family and new capabilities
      The need for sensitivity - The CytoFlex family and new capabilities
      Our Imaging and Cytometry Core Lab is in the Bioscience Technology Facility that serves a multidisciplinary Department of Biology as well as external users through our open access approach.&n...
      Speaker: Professor Peter O'Toole , Dr. Karen Hogg
      Sponsored By: Beckman Coulter Life Sciences
      4 1
      JUN 21, 2018 | 12:00 PM
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
      Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 10:30 AM
      Setting Up Next-Generation Sequencing for the Needs of Routine Molecular Diagnostics With a Focus on the Suitability of the GeneReader NGS System for Lung Cancer Patients
      Setting Up Next-Generation Sequencing for the Needs of Routine...
      The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
      Speaker: Paul Hofman, MD, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      JUN 21, 2018 | 9:00 AM
      Can AI Beat Cancer?
      Can AI Beat Cancer?
      Finding effective treatments for cancer is fundamentally  a high-dimensional probabilistic planning, search, and optimization problem, characterized by  thousands of molecular subty...
      Speaker: Marty Tenenbaum, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 7:30 AM
      Keynote Presentation: Paving the Path Towards Precision Medicine in Inflammatory Bowel Diseases
      Keynote Presentation: Paving the Path Towards Precision Medicine...
      Crohn’s disease and ulcerative colitis also known as inflammatory bowel diseases or IBD, are characterized by chronic, recurrent inflammation of the gastrointestinal tract, which result...
      Speaker: Andres Hurtado-Lorenzo, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 12:00 PM
      Precision Medicine: The Way Forward!
      Precision Medicine: The Way Forward!
      Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
      Speaker: Prasun Mishra, MsC, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 10:30 AM
      Panel Discussion: VA Genomics - The Clinic and Research
      Panel Discussion: VA Genomics - The Clinic and Research
      With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is...
      Speaker: Laurence Meyer, MD, PhD , Ronald Przygodzki, MD
      Presented at: Precision Medicine Virtual Event Series 2018
      2
      JUN 20, 2018 | 9:00 AM
      Identifying Driver Alterations and Therapeutic Options in Cancer
      Identifying Driver Alterations and Therapeutic Options in Cancer
      With prospective clinical sequencing of tumors emerging as a mainstay in cancer care, there is an urgent need for clinical support tools that aid clinicians in their decision making. To this...
      Speaker: Nikolaus Schultz, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 7:30 AM
      Keynote Presentation: Supporting Precision Medicine and Clinical Research at Scale - Challenges and Opportunities
      Keynote Presentation: Supporting Precision Medicine and Clinical...
      Precision medicine based on molecular profiling is moving from the realm of clinical utility studies towards standard of care. There remain, however, significant technological and implementat...
      Speaker: Niall Lennon, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 6:00 AM
      Standardized Precision Medicine? - A Quality Management Perspective on NGS-based Individualized Therapies
      Standardized Precision Medicine? - A Quality Management Perspective...
      Precision medicine and next-generation sequencing – Two terms characterized by a highly dynamic nature, strong innovations and a bright future. Both merged together will exert a decisiv...
      Speaker: Christoph Endrullat, MS
      Presented at: Precision Medicine Virtual Event Series 2018
      2
      JUN 05, 2018 | 6:30 AM
      Handling of viscous liquids - Basics, Techniques and Tricks
      Handling of viscous liquids - Basics, Techniques and Tricks
      DATE: June 5, 2018TIME: 06:30AM PDT, 3:30PM CEST Viscous liquids are a challenge in every lab that deals with them. Depending on how viscous a liquid is, pipetting is either...
      Speaker: Hanae Henke, PhD
      Sponsored By: Eppendorf
      19 25
      MAY 31, 2018 | 1:30 PM
      Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
      Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
      The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
      Speaker: Sabeth Verpoorte, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
    SEP 18, 2018 | 9:00 AM
    Validation of clinical LC-MS/MS methods: What you need to know
    Validation of clinical LC-MS/MS methods: What you need to know
    DATE: September 18, 2018TIME: 9:00AM PDTLC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over m...
    Speaker: Deborah French, Ph,D., DABCC (CC, TC), FAACC
    12 1
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
    SEP 12, 2018 | 8:00 AM
    Advancing precision immunotherapy through next generation sequencing of T-cell receptors: Part II
    Advancing precision immunotherapy through next generation sequencing...
    DATE:  September 12, 2018 TIME:  08:00am PDT, 11:00am EDT In the last presentation of this webinar series, we will continue our discussions on recent advancements i...
    Speaker: Timothy Looney, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    9
    SEP 11, 2018 | 7:00 AM
    Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
    Answering the Challenges of Cell Viability and Reporter Gene Assays...
    DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
    Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
    Sponsored By: Revvity
    5
    AUG 16, 2018 | 8:00 AM
    Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
    Advancing precision immunotherapy through next-generation sequencing...
    DATE: August, 16, 2018TIME: 08:00AM PDTThis webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards...
    Speaker: Timothy Looney, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    7
     
     
  • AUG 09, 2018 | 7:00 AM
    3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
    3D Cell Cultures and Tissue Clearing: A High Content Confocal...
    With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
    Speaker: Michael Johnson, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    AUG 07, 2018 | 8:00 AM
    Using Reference Standards to Validate your NGS Oncology Workflow
    Using Reference Standards to Validate your NGS Oncology Workflow
    DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
    Speaker: Hannah Child, PhD
    Sponsored By: Horizon Discovery
    10 1
    JUL 19, 2018 | 9:00 AM
    Investigating the role of microRNAs in pancreatic cancer progression
    Investigating the role of microRNAs in pancreatic cancer progression
    DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
    Speaker: Silvia Ottaviani, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 5
    JUL 12, 2018 | 8:00 AM
    Little and Large - Using the flexibility of the MoFlo Astrios from sorting bacteria, through the more classic blood and human cells through to plant protoplasts!
    Little and Large - Using the flexibility of the MoFlo Astrios...
    Our MoFlo Astrios serves or multidisciplinary Department of Biology through our open access Bioscience Technology Imaging and Cytometry Core Lab at the University of York. As a core instrumen...
    Speaker: Dr. Karen Hogg , Professor Peter O'Toole
    Sponsored By: Beckman Coulter Life Sciences
    4
    JUN 29, 2018 | 9:00 AM
    Diet and gene interactions in the control of central cell metabolism
    Diet and gene interactions in the control of central cell metabolism
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Speaker: Sophie Prosolek
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 2
     
     
  • JUN 28, 2018 | 8:00 AM
    Isolation of immune cells Straight From whole blood, buffy coat, LRSC, and Leukopak without density gradients
    Isolation of immune cells Straight From whole blood, buffy coat,...
    DATE: June 28, 2018TIME: 8:00AM PDTEnrichment of leukocytes from blood products like buffy coat, leukocyte reduction chambers (LRSC) or leukapheresis material can be time consuming...
    Speaker: Zhong Yu, PhD , Gregory Winkels, MS
    Sponsored By: Miltenyi Biotec
    13 2
    JUN 27, 2018 | 8:00 AM
    Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize success
    Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize...
    DATE: June 27, 2018TIME: 08:00AM PDT CRISPR-Cas9 is a very versatile tool to discover more about your pathway or gene of interest. Its simplicity has led to an explosion in a...
    Speaker: Laura Carleton, PhD
    Sponsored By: Horizon Discovery
    13 1
    JUN 26, 2018 | 8:00 AM
    The need for sensitivity - The CytoFlex family and new capabilities
    The need for sensitivity - The CytoFlex family and new capabilities
    Our Imaging and Cytometry Core Lab is in the Bioscience Technology Facility that serves a multidisciplinary Department of Biology as well as external users through our open access approach.&n...
    Speaker: Professor Peter O'Toole , Dr. Karen Hogg
    Sponsored By: Beckman Coulter Life Sciences
    4 1
    JUN 21, 2018 | 12:00 PM
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
    Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 10:30 AM
    Setting Up Next-Generation Sequencing for the Needs of Routine Molecular Diagnostics With a Focus on the Suitability of the GeneReader NGS System for Lung Cancer Patients
    Setting Up Next-Generation Sequencing for the Needs of Routine...
    The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
    Speaker: Paul Hofman, MD, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
     
     
  • JUN 21, 2018 | 9:00 AM
    Can AI Beat Cancer?
    Can AI Beat Cancer?
    Finding effective treatments for cancer is fundamentally  a high-dimensional probabilistic planning, search, and optimization problem, characterized by  thousands of molecular subty...
    Speaker: Marty Tenenbaum, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 7:30 AM
    Keynote Presentation: Paving the Path Towards Precision Medicine in Inflammatory Bowel Diseases
    Keynote Presentation: Paving the Path Towards Precision Medicine...
    Crohn’s disease and ulcerative colitis also known as inflammatory bowel diseases or IBD, are characterized by chronic, recurrent inflammation of the gastrointestinal tract, which result...
    Speaker: Andres Hurtado-Lorenzo, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 20, 2018 | 12:00 PM
    Precision Medicine: The Way Forward!
    Precision Medicine: The Way Forward!
    Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
    Speaker: Prasun Mishra, MsC, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 20, 2018 | 10:30 AM
    Panel Discussion: VA Genomics - The Clinic and Research
    Panel Discussion: VA Genomics - The Clinic and Research
    With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is...
    Speaker: Laurence Meyer, MD, PhD , Ronald Przygodzki, MD
    Presented at: Precision Medicine Virtual Event Series 2018
    2
    JUN 20, 2018 | 9:00 AM
    Identifying Driver Alterations and Therapeutic Options in Cancer
    Identifying Driver Alterations and Therapeutic Options in Cancer
    With prospective clinical sequencing of tumors emerging as a mainstay in cancer care, there is an urgent need for clinical support tools that aid clinicians in their decision making. To this...
    Speaker: Nikolaus Schultz, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
     
     
  • JUN 20, 2018 | 7:30 AM
    Keynote Presentation: Supporting Precision Medicine and Clinical Research at Scale - Challenges and Opportunities
    Keynote Presentation: Supporting Precision Medicine and Clinical...
    Precision medicine based on molecular profiling is moving from the realm of clinical utility studies towards standard of care. There remain, however, significant technological and implementat...
    Speaker: Niall Lennon, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 20, 2018 | 6:00 AM
    Standardized Precision Medicine? - A Quality Management Perspective on NGS-based Individualized Therapies
    Standardized Precision Medicine? - A Quality Management Perspective...
    Precision medicine and next-generation sequencing – Two terms characterized by a highly dynamic nature, strong innovations and a bright future. Both merged together will exert a decisiv...
    Speaker: Christoph Endrullat, MS
    Presented at: Precision Medicine Virtual Event Series 2018
    2
    JUN 05, 2018 | 6:30 AM
    Handling of viscous liquids - Basics, Techniques and Tricks
    Handling of viscous liquids - Basics, Techniques and Tricks
    DATE: June 5, 2018TIME: 06:30AM PDT, 3:30PM CEST Viscous liquids are a challenge in every lab that deals with them. Depending on how viscous a liquid is, pipetting is either...
    Speaker: Hanae Henke, PhD
    Sponsored By: Eppendorf
    19 25
    MAY 31, 2018 | 1:30 PM
    Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
    Organ-on-a-Chip: Improving Biological Insight Using In Vitro Microtechnology
    The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
    Speaker: Sabeth Verpoorte, PhD
    Presented at: Lab Automation Virtual Event Series 2018
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