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    DNA Sequencing

    DNA Sequencing: the process of determining the precise order of nucleotides within a DNA molecule. It includes any method or technology that is used to determine the order of the four bases-adenine, guanine, cytosine, and thymine-in a strand of DNA. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery.

    Webinars

    • OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 03, 2018 | 12:00 PM
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
      Speaker: Dipali Sashital, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
      OCT 03, 2018 | 9:00 AM
      CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs in CRISPR-Cas9 Genome-Editing Systems
      CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs...
      The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
      Speaker: Lihua Julie Zhu, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
      SEP 27, 2018 | 8:00 AM
      Achieving higher throughput with multiplexed phage display
      Achieving higher throughput with multiplexed phage display
      DATE: September 27, 2018TIME: 8:00AM PDTRecent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gap...
      Speaker: Thomas Hengstl, PhD
      Sponsored By: ForteBio LLC
      6
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      AUG 07, 2018 | 8:00 AM
      Using Reference Standards to Validate your NGS Oncology Workflow
      Using Reference Standards to Validate your NGS Oncology Workflow
      DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
      Speaker: Hannah Child, PhD
      Sponsored By: Horizon Discovery
      10 1
      JUN 21, 2018 | 12:00 PM
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
      Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      MAY 29, 2018 | 9:00 AM
      Dissecting the Tumor Microenvironment Part 2 - Tools for isolation and flow analysis
      Dissecting the Tumor Microenvironment Part 2 - Tools for isolation...
      Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
      Speaker: César Evaristo, PhD
      Sponsored By: Miltenyi Biotec
      7
      MAY 24, 2018 | 9:00 AM
      Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation and Flow Analysis
      Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation...
      Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
      Speaker: Olaf Hardt, PhD
      Sponsored By: Miltenyi Biotec
      8 2
      MAY 10, 2018 | 10:30 AM
      C.E. CREDITS
      Strain Level Microbiome Profiling Using rRNA Gene Amplicons
      Strain Level Microbiome Profiling Using rRNA Gene Amplicons
      An ideal microbiome profiling method would produce strain level taxonomic classification of organisms and their relative quantities. We demonstrate proof of principle experiments that sequenc...
      Speaker: Mark Driscoll, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 10, 2018 | 6:00 AM
      C.E. CREDITS
      Multiplexed Precision Genome Editing with Trackable Genome-Integrated Barcodes in Yeast
      Multiplexed Precision Genome Editing with Trackable Genome-Integrated...
      Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. In this pr...
      Speaker: Kevin Roy, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 09, 2018 | 1:30 PM
      C.E. CREDITS
      Bimodal Gene Expression in Breast Cancer
      Bimodal Gene Expression in Breast Cancer
      Tumors are often categorized into standard molecular subtypes. However, largescale studies have demonstrated that patient heterogeneity in the regulatory make-up of tumors remain. At the tran...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 09, 2018 | 7:30 AM
      C.E. CREDITS
      Keynote Presentation: Informing Clinical Interpretations of Structural Chromosome Rearrangements:  Implementing Evolving Knowledge from Chromatin Structure
      Keynote Presentation: Informing Clinical Interpretations of Structural...
      The arrangement of chromatin inside the nucleus has long been recognized as a key element in genomic stability and an active participant in transcriptional control. With the development and d...
      Speaker: Cynthia Morton, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      3
      MAY 03, 2018 | 11:00 AM
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
      DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
      Speaker: Sisi Li
      Sponsored By: Covaris
      5 2
      APR 24, 2018 | 8:00 AM
      KASP genotyping - better by design
      KASP genotyping - better by design
      DATE: April 24, 2018TIME: 8:00AM PSTIn this talk we will cover basic principles of KASP® genotyping chemistry and designing assays that are specific to desired targets. We will go o...
      Speaker: Jonathan Curry, PhD
      Sponsored By: LGC Seracare
      13
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      APR 12, 2018 | 12:00 PM
      Standards for Mixed Pathogen Detection via Metagenomics
      Standards for Mixed Pathogen Detection via Metagenomics
      I will update the current state of our candidate RM 8376 for mixed microbial DNA detection via NGS-based sequencing and metagenomics. After community engagement to understand the metrological...
      Speaker: Jason Kralj, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      APR 12, 2018 | 9:00 AM
      QIAseq Digital Sequencing and Biomedical Genomics Workbench: Application to Liquid Biopsy in Bladder Cancer Research
      QIAseq Digital Sequencing and Biomedical Genomics Workbench: Application...
      This presentation illustrates the features of QIAGEN sample to insight approach, and how it combines a powerful chemistry based on unique molecular indexes (UMIs) and a UMI-aware bioinformati...
      Speaker: Francesco Lescai, PhD, EDBT
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      Sponsored By: QIAGEN Molecular Diagnostics
      1
      APR 12, 2018 | 9:00 AM
      Metabolites, Germs and People: Eavesdropping on Human Microbial Communities
      Metabolites, Germs and People: Eavesdropping on Human Microbial...
      The Whiteson lab uses culture-independent metagenomics, metabolomics, and ecological statistics along with hypothesis driven, reductionist microbiology to answer questions about how bacteria...
      Speaker: Katrine Whiteson, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      APR 11, 2018 | 12:00 PM
      Emerging Trends: Cell Free (cf)DNA-Based Screening for Common Aneuploidies
      Emerging Trends: Cell Free (cf)DNA-Based Screening for Common...
      Screening for Down syndrome began with the question "How old will you be when you deliver?".  If the pregnant woman answered 35 years of age or older, she was offered amniocent...
      Speaker: Glenn Palomaki, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      APR 11, 2018 | 10:30 AM
      Medicare's New National Coverage Determination for Next Generation Sequencing: What Does it Mean for Diagnostic Laboratories?
      Medicare's New National Coverage Determination for Next Generation...
      On March 16, 2018, the Centers for Medicare and Medicaid Services (CMS) finalized a National Coverage Determination (NCD) for the use of Next Generation Sequencing (NGS) for tumor profiling i...
      Speaker: Roger Klein MD, JD, FCAP
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      APR 11, 2018 | 6:00 AM
      Sharing Data about Genomic Variants:  A Clinical and Scientific Imperative
      Sharing Data about Genomic Variants: A Clinical and Scientific...
      Next-generation DNA sequencing began to enter the clinic a decade ago, a half decade after the draft human reference sequence was published.  The discovery of new genes, new variants of...
      Speaker: Robert Cook-Deegan, MD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      2
      MAR 29, 2018 | 12:00 PM
      Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
      Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
      It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
      Speaker: Judy Mikovits, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 03, 2018 | 12:00 PM
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
    Speaker: Dipali Sashital, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
    OCT 03, 2018 | 9:00 AM
    CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs in CRISPR-Cas9 Genome-Editing Systems
    CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs...
    The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
    Speaker: Lihua Julie Zhu, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
    SEP 27, 2018 | 8:00 AM
    Achieving higher throughput with multiplexed phage display
    Achieving higher throughput with multiplexed phage display
    DATE: September 27, 2018TIME: 8:00AM PDTRecent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gap...
    Speaker: Thomas Hengstl, PhD
    Sponsored By: ForteBio LLC
    6
     
     
  • SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
    AUG 07, 2018 | 8:00 AM
    Using Reference Standards to Validate your NGS Oncology Workflow
    Using Reference Standards to Validate your NGS Oncology Workflow
    DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
    Speaker: Hannah Child, PhD
    Sponsored By: Horizon Discovery
    10 1
    JUN 21, 2018 | 12:00 PM
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
    Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    MAY 29, 2018 | 9:00 AM
    Dissecting the Tumor Microenvironment Part 2 - Tools for isolation and flow analysis
    Dissecting the Tumor Microenvironment Part 2 - Tools for isolation...
    Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
    Speaker: César Evaristo, PhD
    Sponsored By: Miltenyi Biotec
    7
    MAY 24, 2018 | 9:00 AM
    Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation and Flow Analysis
    Dissecting the Tumor Microenvironment Part 1 - Tools for Isolation...
    Recent advances in immuno-oncology research has proven the critical role of immune cells in cancer therapy. Deep understanding of the interaction and phenotype of immune and tumor cells withi...
    Speaker: Olaf Hardt, PhD
    Sponsored By: Miltenyi Biotec
    8 2
     
     
  • MAY 10, 2018 | 10:30 AM
    C.E. CREDITS
    Strain Level Microbiome Profiling Using rRNA Gene Amplicons
    Strain Level Microbiome Profiling Using rRNA Gene Amplicons
    An ideal microbiome profiling method would produce strain level taxonomic classification of organisms and their relative quantities. We demonstrate proof of principle experiments that sequenc...
    Speaker: Mark Driscoll, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    MAY 10, 2018 | 6:00 AM
    C.E. CREDITS
    Multiplexed Precision Genome Editing with Trackable Genome-Integrated Barcodes in Yeast
    Multiplexed Precision Genome Editing with Trackable Genome-Integrated...
    Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. In this pr...
    Speaker: Kevin Roy, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    MAY 09, 2018 | 1:30 PM
    C.E. CREDITS
    Bimodal Gene Expression in Breast Cancer
    Bimodal Gene Expression in Breast Cancer
    Tumors are often categorized into standard molecular subtypes. However, largescale studies have demonstrated that patient heterogeneity in the regulatory make-up of tumors remain. At the tran...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    MAY 09, 2018 | 7:30 AM
    C.E. CREDITS
    Keynote Presentation: Informing Clinical Interpretations of Structural Chromosome Rearrangements:  Implementing Evolving Knowledge from Chromatin Structure
    Keynote Presentation: Informing Clinical Interpretations of Structural...
    The arrangement of chromatin inside the nucleus has long been recognized as a key element in genomic stability and an active participant in transcriptional control. With the development and d...
    Speaker: Cynthia Morton, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    3
    MAY 03, 2018 | 11:00 AM
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    Speaker: Sisi Li
    Sponsored By: Covaris
    5 2
     
     
  • APR 24, 2018 | 8:00 AM
    KASP genotyping - better by design
    KASP genotyping - better by design
    DATE: April 24, 2018TIME: 8:00AM PSTIn this talk we will cover basic principles of KASP® genotyping chemistry and designing assays that are specific to desired targets. We will go o...
    Speaker: Jonathan Curry, PhD
    Sponsored By: LGC Seracare
    13
    APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    APR 12, 2018 | 12:00 PM
    Standards for Mixed Pathogen Detection via Metagenomics
    Standards for Mixed Pathogen Detection via Metagenomics
    I will update the current state of our candidate RM 8376 for mixed microbial DNA detection via NGS-based sequencing and metagenomics. After community engagement to understand the metrological...
    Speaker: Jason Kralj, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    APR 12, 2018 | 9:00 AM
    QIAseq Digital Sequencing and Biomedical Genomics Workbench: Application to Liquid Biopsy in Bladder Cancer Research
    QIAseq Digital Sequencing and Biomedical Genomics Workbench: Application...
    This presentation illustrates the features of QIAGEN sample to insight approach, and how it combines a powerful chemistry based on unique molecular indexes (UMIs) and a UMI-aware bioinformati...
    Speaker: Francesco Lescai, PhD, EDBT
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    Sponsored By: QIAGEN Molecular Diagnostics
    1
    APR 12, 2018 | 9:00 AM
    Metabolites, Germs and People: Eavesdropping on Human Microbial Communities
    Metabolites, Germs and People: Eavesdropping on Human Microbial...
    The Whiteson lab uses culture-independent metagenomics, metabolomics, and ecological statistics along with hypothesis driven, reductionist microbiology to answer questions about how bacteria...
    Speaker: Katrine Whiteson, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
     
     
  • APR 11, 2018 | 12:00 PM
    Emerging Trends: Cell Free (cf)DNA-Based Screening for Common Aneuploidies
    Emerging Trends: Cell Free (cf)DNA-Based Screening for Common...
    Screening for Down syndrome began with the question "How old will you be when you deliver?".  If the pregnant woman answered 35 years of age or older, she was offered amniocent...
    Speaker: Glenn Palomaki, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    APR 11, 2018 | 10:30 AM
    Medicare's New National Coverage Determination for Next Generation Sequencing: What Does it Mean for Diagnostic Laboratories?
    Medicare's New National Coverage Determination for Next Generation...
    On March 16, 2018, the Centers for Medicare and Medicaid Services (CMS) finalized a National Coverage Determination (NCD) for the use of Next Generation Sequencing (NGS) for tumor profiling i...
    Speaker: Roger Klein MD, JD, FCAP
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    APR 11, 2018 | 6:00 AM
    Sharing Data about Genomic Variants:  A Clinical and Scientific Imperative
    Sharing Data about Genomic Variants: A Clinical and Scientific...
    Next-generation DNA sequencing began to enter the clinic a decade ago, a half decade after the draft human reference sequence was published.  The discovery of new genes, new variants of...
    Speaker: Robert Cook-Deegan, MD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    2
    MAR 29, 2018 | 12:00 PM
    Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
    Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
    It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
    Speaker: Judy Mikovits, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
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