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    In Vivo

    In Vivo: are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

    Webinars

    • FEB 27, 2019 | 3:00 PM
      Do You Have the Gut-on-a-Chip?
      Do You Have the Gut-on-a-Chip?
      In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
      Speaker: Elena Naumovska, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 1:30 PM
      Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
      Advances in Three-Dimensional Cell Culture in Drug Research and...
      Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
      Speaker: Richard Eglen, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 12:00 PM
      Studies on Malignancies With a Novel Proliferation Biomarker
      Studies on Malignancies With a Novel Proliferation Biomarker
      Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
      Speaker: Martin Shaw
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and Their Avoidance
      In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and...
      Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
      Speaker: Matthew Flegal, BS, SRS
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 26, 2019 | 11:00 AM
      Osteosarcoma research
      Osteosarcoma research
      DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
      Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      FEB 20, 2019 | 9:00 AM
      Choosing the best system to answer your question - What question are you looking to answer?
      Choosing the best system to answer your question - What question...
      DATE:  February 20, 2019TIME:  9:00am PST  ...
      Speaker: David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      15 1
      FEB 14, 2019 | 1:30 PM
      Organs On a Chip:  A Revolution in Drug Development?
      Organs On a Chip: A Revolution in Drug Development?
      Pharmaceutical research and development efforts are often both inefficient and suffer from a high attrition rate of drug candidates within the clinical phase of development.  Most drug t...
      Speaker: Gorm Yoder, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 2
      FEB 14, 2019 | 12:00 PM
      Application of Micro-Physiological Systems for Respiratory Drug Discovery: Opportunities and Challenges
      Application of Micro-Physiological Systems for Respiratory Drug...
      The lung is a highly complex organ, comprised of more than 40 cell types that are responsible for various important functions, the lung’s complexity contributes to the subsequent challe...
      Speaker: David Rowlands, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      1
      FEB 14, 2019 | 10:30 AM
      Integrating In Vitro Microtissues and In Vivo endpoints in Drug Discovery & Development
      Integrating In Vitro Microtissues and In Vivo endpoints in Drug...
      This presentation will discuss and review the promise and potential of 3D Microtissues, and the challenges of using these Microtissues as Hazard ID tools. Lastly, we will discuss the potentia...
      Speaker: Matthew Wagoner, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      FEB 13, 2019 | 1:30 PM
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
      Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5
      FEB 13, 2019 | 12:00 PM
      Automatic Detection and Classification of Behaviour in Laboratory Animals
      Automatic Detection and Classification of Behaviour in Laboratory...
      Animal welfare is the most important issue in any in vivo laboratory. The ability to detect and intervene in cases where the conditions of animals may be deteriorating as well as the ability...
      Speaker: Patrick Sweeney, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      4
      FEB 13, 2019 | 10:30 AM
      Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
      Accurate Clinical Concentration-Response Predictions for Cardiac...
      Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
      Speaker: Weihsueh Chiu, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 1
      FEB 13, 2019 | 7:30 AM
      Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
      Keynote Presentation: Modernizing Drug Development Through Digital...
      Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      6
      JAN 31, 2019 | 1:30 PM
      Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
      Standardization of Cell Viability Assays in Primary Cells as a...
      Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
      Speaker: Simon Kaja, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      2
      JAN 29, 2019 | 9:00 AM
      Targeting prostate cancer stem cells with T cell immunotherapy
      Targeting prostate cancer stem cells with T cell immunotherapy
      DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
      Speaker: Amy Codd
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      DEC 13, 2018 | 9:00 AM
      Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using Models of Endocrine Resistance
      Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using...
      DATE: December 13 15,2018TIME: 09:00am PST, 12:00pm EST Breast cancers are classified into three main subtypes according to their receptor status: estrogen receptor-positive...
      Speaker: Hillary Stires, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      DEC 10, 2018 | 10:00 PM
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
      DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
      Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
      Sponsored By: Revvity
      4 1
      DEC 06, 2018 | 7:00 AM
      Image-based screening for precision medicine and immunotherapy
      Image-based screening for precision medicine and immunotherapy
      DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
      Speaker: Dr. Gregory Vladimer
      Sponsored By: Revvity
      6
      DEC 06, 2018 | 8:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      2
      DEC 05, 2018 | 8:00 PM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      5 3
      DEC 06, 2018 | 1:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      8
      DEC 05, 2018 | 7:00 AM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      NOV 14, 2018 | 3:00 PM
      Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
      Modeling Inflammation and Fibrosis in Humans with PSC-derived...
      Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
      Speaker: Takanori Takebe
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      8
      NOV 13, 2018 | 9:00 AM
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
      DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
      Speaker: Sara Busatto
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
    FEB 27, 2019 | 3:00 PM
    Do You Have the Gut-on-a-Chip?
    Do You Have the Gut-on-a-Chip?
    In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
    Speaker: Elena Naumovska, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 1:30 PM
    Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
    Advances in Three-Dimensional Cell Culture in Drug Research and...
    Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
    Speaker: Richard Eglen, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 12:00 PM
    Studies on Malignancies With a Novel Proliferation Biomarker
    Studies on Malignancies With a Novel Proliferation Biomarker
    Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
    Speaker: Martin Shaw
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and Their Avoidance
    In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and...
    Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
    Speaker: Matthew Flegal, BS, SRS
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 26, 2019 | 11:00 AM
    Osteosarcoma research
    Osteosarcoma research
    DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
    Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
     
     
  • FEB 20, 2019 | 9:00 AM
    Choosing the best system to answer your question - What question are you looking to answer?
    Choosing the best system to answer your question - What question...
    DATE:  February 20, 2019TIME:  9:00am PST  ...
    Speaker: David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
    15 1
    FEB 14, 2019 | 1:30 PM
    Organs On a Chip:  A Revolution in Drug Development?
    Organs On a Chip: A Revolution in Drug Development?
    Pharmaceutical research and development efforts are often both inefficient and suffer from a high attrition rate of drug candidates within the clinical phase of development.  Most drug t...
    Speaker: Gorm Yoder, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 2
    FEB 14, 2019 | 12:00 PM
    Application of Micro-Physiological Systems for Respiratory Drug Discovery: Opportunities and Challenges
    Application of Micro-Physiological Systems for Respiratory Drug...
    The lung is a highly complex organ, comprised of more than 40 cell types that are responsible for various important functions, the lung’s complexity contributes to the subsequent challe...
    Speaker: David Rowlands, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    1
    FEB 14, 2019 | 10:30 AM
    Integrating In Vitro Microtissues and In Vivo endpoints in Drug Discovery & Development
    Integrating In Vitro Microtissues and In Vivo endpoints in Drug...
    This presentation will discuss and review the promise and potential of 3D Microtissues, and the challenges of using these Microtissues as Hazard ID tools. Lastly, we will discuss the potentia...
    Speaker: Matthew Wagoner, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
    FEB 13, 2019 | 1:30 PM
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
    Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5
     
     
  • FEB 13, 2019 | 12:00 PM
    Automatic Detection and Classification of Behaviour in Laboratory Animals
    Automatic Detection and Classification of Behaviour in Laboratory...
    Animal welfare is the most important issue in any in vivo laboratory. The ability to detect and intervene in cases where the conditions of animals may be deteriorating as well as the ability...
    Speaker: Patrick Sweeney, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    4
    FEB 13, 2019 | 10:30 AM
    Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
    Accurate Clinical Concentration-Response Predictions for Cardiac...
    Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
    Speaker: Weihsueh Chiu, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 1
    FEB 13, 2019 | 7:30 AM
    Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
    Keynote Presentation: Modernizing Drug Development Through Digital...
    Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    6
    JAN 31, 2019 | 1:30 PM
    Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
    Standardization of Cell Viability Assays in Primary Cells as a...
    Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
    Speaker: Simon Kaja, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    2
    JAN 29, 2019 | 9:00 AM
    Targeting prostate cancer stem cells with T cell immunotherapy
    Targeting prostate cancer stem cells with T cell immunotherapy
    DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
    Speaker: Amy Codd
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
     
     
  • DEC 13, 2018 | 9:00 AM
    Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using Models of Endocrine Resistance
    Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using...
    DATE: December 13 15,2018TIME: 09:00am PST, 12:00pm EST Breast cancers are classified into three main subtypes according to their receptor status: estrogen receptor-positive...
    Speaker: Hillary Stires, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    DEC 10, 2018 | 10:00 PM
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
    DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
    Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
    Sponsored By: Revvity
    4 1
    DEC 06, 2018 | 7:00 AM
    Image-based screening for precision medicine and immunotherapy
    Image-based screening for precision medicine and immunotherapy
    DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
    Speaker: Dr. Gregory Vladimer
    Sponsored By: Revvity
    6
    DEC 06, 2018 | 8:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    2
    DEC 05, 2018 | 8:00 PM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    5 3
     
     
  • DEC 06, 2018 | 1:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    8
    DEC 05, 2018 | 7:00 AM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    NOV 14, 2018 | 3:00 PM
    Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
    Modeling Inflammation and Fibrosis in Humans with PSC-derived...
    Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
    Speaker: Takanori Takebe
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    8
    NOV 13, 2018 | 9:00 AM
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
    DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
    Speaker: Sara Busatto
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
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