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    Molecular Pharmacology

    Molecular Pharmacology: broadcast conclusions derived from the application of innovative structural biology, biophysics, biochemistry, physiology, genetics, and molecular biology to basic pharmacological problems that provide mechanistic observations that are broadly important for the fields of pharmacology and toxicology.

    Webinars

    • APR 10, 2019 | 6:00 AM
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      6
      APR 10, 2019 | 6:00 AM
      Bio-Rad Unity as a Solution for Molecular Quality Control Data Management
      Bio-Rad Unity as a Solution for Molecular Quality Control Data...
      Management of complex quality control (QC) data is essential to insure high quality patient care and maintain regulatory compliance within clinical laboratories. Robust software solutions fo...
      Speaker: Duane Newton, PhD, D(ABMM), FIDSA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Bio-Rad Laboratories
      10
      MAR 28, 2019 | 12:00 PM
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
      Speaker: Debra Kimless, MD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      6
      MAR 28, 2019 | 10:30 AM
      Medical Cannabis Pharmacogenomics and Drug Interactions
      Medical Cannabis Pharmacogenomics and Drug Interactions
      The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
      Speaker: Jahan Marcu, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      3
      FEB 27, 2019 | 3:00 PM
      Do You Have the Gut-on-a-Chip?
      Do You Have the Gut-on-a-Chip?
      In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
      Speaker: Elena Naumovska, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 3:00 PM
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
      In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
      Speaker: Jagath Reddy Junutula, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 3:00 PM
      Automation Meets Cell Separation: Primary Cells for Drug Discovery Assays
      Automation Meets Cell Separation: Primary Cells for Drug Discovery...
      Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
      Speaker: Lotta Raty
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Miltenyi Biotec
      2
      FEB 27, 2019 | 3:00 PM
      BASKET Trials: Biomarker Driven Drug Development
      BASKET Trials: Biomarker Driven Drug Development
      Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
      Speaker: Shivaani Kummar, MD, FACP
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 1:30 PM
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
      NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
      Speaker: Phillip Febbo, MD , Maude Champagne
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Illumina
      4
      FEB 27, 2019 | 12:00 PM
      Why Pain Control Is Good Science-The Scientific Rationale
      Why Pain Control Is Good Science-The Scientific Rationale
      Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      FEB 27, 2019 | 12:00 PM
      Nanostructured Molecularly Imprinted Polymers: Robust, Stable and Selective Alternatives to Antibodies
      Nanostructured Molecularly Imprinted Polymers: Robust, Stable...
      NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
      Speaker: Adrian Kinkaid
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      Developing Precision Combination Therapies to Overcome Evolution of Therapeutic Resistance
      Developing Precision Combination Therapies to Overcome Evolution...
      Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
      An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
      Speaker: G. Thomas Caltagirone, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      FEB 27, 2019 | 7:30 AM
      Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
      Keynote Presentation: Second Harmonic Generation Detection of...
      Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
      Speaker: Frank McCormick, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 6:00 AM
      Biomarkers of Aging
      Biomarkers of Aging
      Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
      Speaker: Alex Zhavoronkov, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 14, 2019 | 10:30 AM
      Integrating In Vitro Microtissues and In Vivo endpoints in Drug Discovery & Development
      Integrating In Vitro Microtissues and In Vivo endpoints in Drug...
      This presentation will discuss and review the promise and potential of 3D Microtissues, and the challenges of using these Microtissues as Hazard ID tools. Lastly, we will discuss the potentia...
      Speaker: Matthew Wagoner, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      JAN 31, 2019 | 1:30 PM
      Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
      Standardization of Cell Viability Assays in Primary Cells as a...
      Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
      Speaker: Simon Kaja, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      2
      DEC 13, 2018 | 6:00 AM
      Procalcitonina, una herramienta eficaz en la gestión del tratamiento antibiótico
      Procalcitonina, una herramienta eficaz en la gestión del tratamiento...
      DATE:    December 13, 2018TIME:    6:00am PT, 3:00pm CET La complejidad de los pacientes hospitalizados con sospecha de infección suscita...
      Speaker: Dr. Javier Cobo , Dr. Ignacio Arribas
      Sponsored By: Abbott
      5
      DEC 10, 2018 | 10:00 PM
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
      DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
      Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
      Sponsored By: Revvity
      4 1
      NOV 15, 2018 | 1:30 PM
      Washington's New Opioid Prescribing Rules
      Washington's New Opioid Prescribing Rules
      In 2017, the Washington State Legislature passed HB 1427, which mandated that boards and commissions for five prescribing professions (dental, medical, nursing, osteopathic, and podiatric) en...
      Speaker: Blake Maresh, MPA, CMBE
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      1
      NOV 15, 2018 | 12:00 PM
      The Washington State Department of Health's Prescription Monitoring Program - Ensuring Safe Prescribing
      The Washington State Department of Health's Prescription Monitoring...
      Drug overdose surpassed motor vehicle accidents as the leading cause of accidental death 2006 and has remained the leading cause of accidental death at the state and national level.  Mos...
      Speaker: Gary Garrety
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      1
      NOV 15, 2018 | 12:00 PM
      Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
      Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
      QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present a lung cancer case study to show how QIAG...
      Speaker: Raed Samara, PhD , Dan Richards, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      Sponsored By: QIAGEN
      2
    APR 10, 2019 | 6:00 AM
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    6
    APR 10, 2019 | 6:00 AM
    Bio-Rad Unity as a Solution for Molecular Quality Control Data Management
    Bio-Rad Unity as a Solution for Molecular Quality Control Data...
    Management of complex quality control (QC) data is essential to insure high quality patient care and maintain regulatory compliance within clinical laboratories. Robust software solutions fo...
    Speaker: Duane Newton, PhD, D(ABMM), FIDSA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Bio-Rad Laboratories
    10
    MAR 28, 2019 | 12:00 PM
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
    Speaker: Debra Kimless, MD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    6
    MAR 28, 2019 | 10:30 AM
    Medical Cannabis Pharmacogenomics and Drug Interactions
    Medical Cannabis Pharmacogenomics and Drug Interactions
    The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
    Speaker: Jahan Marcu, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    3
    FEB 27, 2019 | 3:00 PM
    Do You Have the Gut-on-a-Chip?
    Do You Have the Gut-on-a-Chip?
    In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
    Speaker: Elena Naumovska, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
     
     
  • FEB 27, 2019 | 3:00 PM
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
    In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
    Speaker: Jagath Reddy Junutula, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 3:00 PM
    Automation Meets Cell Separation: Primary Cells for Drug Discovery Assays
    Automation Meets Cell Separation: Primary Cells for Drug Discovery...
    Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
    Speaker: Lotta Raty
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Miltenyi Biotec
    2
    FEB 27, 2019 | 3:00 PM
    BASKET Trials: Biomarker Driven Drug Development
    BASKET Trials: Biomarker Driven Drug Development
    Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
    Speaker: Shivaani Kummar, MD, FACP
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 1:30 PM
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
    NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
    Speaker: Phillip Febbo, MD , Maude Champagne
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Illumina
    4
    FEB 27, 2019 | 12:00 PM
    Why Pain Control Is Good Science-The Scientific Rationale
    Why Pain Control Is Good Science-The Scientific Rationale
    Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Drug Discovery Virtual Event Series 2019
    1
     
     
  • FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    FEB 27, 2019 | 12:00 PM
    Nanostructured Molecularly Imprinted Polymers: Robust, Stable and Selective Alternatives to Antibodies
    Nanostructured Molecularly Imprinted Polymers: Robust, Stable...
    NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
    Speaker: Adrian Kinkaid
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    Developing Precision Combination Therapies to Overcome Evolution of Therapeutic Resistance
    Developing Precision Combination Therapies to Overcome Evolution...
    Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
    An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
    Speaker: G. Thomas Caltagirone, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
     
     
  • FEB 27, 2019 | 7:30 AM
    Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
    Keynote Presentation: Second Harmonic Generation Detection of...
    Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
    Speaker: Frank McCormick, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 6:00 AM
    Biomarkers of Aging
    Biomarkers of Aging
    Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
    Speaker: Alex Zhavoronkov, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 14, 2019 | 10:30 AM
    Integrating In Vitro Microtissues and In Vivo endpoints in Drug Discovery & Development
    Integrating In Vitro Microtissues and In Vivo endpoints in Drug...
    This presentation will discuss and review the promise and potential of 3D Microtissues, and the challenges of using these Microtissues as Hazard ID tools. Lastly, we will discuss the potentia...
    Speaker: Matthew Wagoner, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
    JAN 31, 2019 | 1:30 PM
    Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
    Standardization of Cell Viability Assays in Primary Cells as a...
    Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
    Speaker: Simon Kaja, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    2
    DEC 13, 2018 | 6:00 AM
    Procalcitonina, una herramienta eficaz en la gestión del tratamiento antibiótico
    Procalcitonina, una herramienta eficaz en la gestión del tratamiento...
    DATE:    December 13, 2018TIME:    6:00am PT, 3:00pm CET La complejidad de los pacientes hospitalizados con sospecha de infección suscita...
    Speaker: Dr. Javier Cobo , Dr. Ignacio Arribas
    Sponsored By: Abbott
    5
     
     
  • DEC 10, 2018 | 10:00 PM
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
    DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
    Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
    Sponsored By: Revvity
    4 1
    NOV 15, 2018 | 1:30 PM
    Washington's New Opioid Prescribing Rules
    Washington's New Opioid Prescribing Rules
    In 2017, the Washington State Legislature passed HB 1427, which mandated that boards and commissions for five prescribing professions (dental, medical, nursing, osteopathic, and podiatric) en...
    Speaker: Blake Maresh, MPA, CMBE
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    1
    NOV 15, 2018 | 12:00 PM
    The Washington State Department of Health's Prescription Monitoring Program - Ensuring Safe Prescribing
    The Washington State Department of Health's Prescription Monitoring...
    Drug overdose surpassed motor vehicle accidents as the leading cause of accidental death 2006 and has remained the leading cause of accidental death at the state and national level.  Mos...
    Speaker: Gary Garrety
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    1
    NOV 15, 2018 | 12:00 PM
    Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
    Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
    QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present a lung cancer case study to show how QIAG...
    Speaker: Raed Samara, PhD , Dan Richards, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    Sponsored By: QIAGEN
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