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    Protein Characterization

    Protein Characterization: involves the use of experimental methods that allow for the detection and isolation of a protein and its purification, as well as the characterization of its structure and function.

    Webinars

    • JAN 21, 2021 | 8:00 AM
      Critical reagent characterization for regulated bioassays accelerated by Uncle
      Critical reagent characterization for regulated bioassays accelerated...
      Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
      Speaker: Ron Bowsher , Adam Kinne , Kevin Lance, Ph.D.
      Sponsored By: Unchained Labs
      6
      DEC 10, 2020 | 8:00 AM
      Simple and Fast Charge Variants Analysis of mAbs by CZE
      Simple and Fast Charge Variants Analysis of mAbs by CZE
      Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
      Speaker: Yan He, Ph.D.
      Sponsored By: SCIEX
      4 1
      DEC 09, 2020 | 8:00 AM
      Nanoscopy Meets Lifetime - Introducing the new STELLARIS 8 Ï„-STED
      Nanoscopy Meets Lifetime - Introducing the new STELLARIS 8 Ï„-STED
      Date: December 89 2020 Time: 8:00am (PST), 11:00am (EST) This talk introduces the Leica STELLARIS 8 τ-STED system where STED Nanoscopy meets Leica’s Fast Lifetime Contrast (FALCON)...
      Speaker: Julia Roberti, Ph.D.
      Sponsored By: Leica Microsystems
      1
      DEC 09, 2020 | 7:00 AM
      Characterization of RNA therapeutics from small to large
      Characterization of RNA therapeutics from small to large
      Date: December 9, 2020 Time: 7:00am (PST), 10:00am (EST) In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messen...
      Speaker: Stephen Lock, PhD
      Sponsored By: SCIEX
      5
      DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      DEC 03, 2020 | 12:00 AM
      Development, assessment and commercialization of serological SARS CoV-2 tests - an interdisciplinary success story
      Development, assessment and commercialization of serological SARS...
      Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
      Speaker: Mark Dürkop, PhD
      Presented at: Coronavirus Series
      3
      NOV 19, 2020 | 9:00 AM
      From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
      From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
      DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
      Speaker: Amal Hassan Ali
      Sponsored By: Thermo Fisher Scientific
      16 1
      NOV 19, 2020 | 8:00 AM
      From discovery to functional assays: therapeutic antibody research by Miltenyi Biotec
      From discovery to functional assays: therapeutic antibody research...
      Date: November 19, 2020 Time: 8:00am PST, 11:00am EST Monoclonal antibody-based drugs have shown great potential as a treatment for several cancers. At Miltenyi Biotec, we offer a complete wo...
      Speaker: Dr. Susanne Bethke
      Sponsored By: Miltenyi Biotec
      9
      NOV 12, 2020 | 10:00 AM
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
      Speaker: Tilman Schlothauer, Ph.D
      Sponsored By: Roche CustomBiotech
      3
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      OCT 21, 2020 | 12:00 AM
      Modification and Analytical Characterization of Polyol Based Polymers for Ice Recrystallization Inhibition and Thermal Hysteresis Activity
      Modification and Analytical Characterization of Polyol Based Polymers...
      Ice formation is a global issue that poses serious challenges for many applications. Certain species in colder regions of the world have adapted to that climate by producing antifreeze (glyc...
      Speaker: John G. Tsavalas, PhD
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      2
      OCT 21, 2020 | 12:00 AM
      Developing a Complete Workflow Including N-Linked Glycans Analysis for Monoclonal Antibodies with High Resolution Mass Spectrometry and Fluorescence Detection
      Developing a Complete Workflow Including N-Linked Glycans Analysis...
      Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
      Speaker: Brian Domanski
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 07, 2020 | 10:30 AM
      Immune correlates of TP53 mutational status in acute myeloid leukemia
      Immune correlates of TP53 mutational status in acute myeloid leukemia
      Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
      Speaker: Dr. Sergio Rutella
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      SEP 30, 2020 | 1:30 PM
      Harnessing novel CRISPR systems for genome engineering
      Harnessing novel CRISPR systems for genome engineering
      RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: IDT
      2
      SEP 30, 2020 | 12:00 AM
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
      CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
      Speaker: Jonas Korlach, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
      Applying targeted long-read sequencing to assess an expanded repeat...
      A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
      Speaker: Marka van Blitterswijk, MD, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 29, 2020 | 7:00 AM
      Considerations in the Use of Analytical Ultracentrifugation for Characterization of AAV Gene Delivery Vectors
      Considerations in the Use of Analytical Ultracentrifugation for...
      Date: September 29, 2020 Time: 10:00am PTD, 1:00pm EDT alytical Ultracentrifugation (AUC) in the biopharmaceutical industry has traditionally been employed in the analysis of aggregation and...
      Speaker: Christopher Sucato
      Sponsored By: Beckman Coulter Life Sciences
      6 1
      SEP 23, 2020 | 1:30 PM
      Keynote Presentation: Starting at the source: tissue extracellular vesicles and Alzheimer's disease
      Keynote Presentation: Starting at the source: tissue extracellular...
      Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
      Speaker: Kenneth W. Witwer, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 PM
      Keynote Presentation: Sorting out the mechanisms of endocytic recycling
      Keynote Presentation: Sorting out the mechanisms of endocytic...
      Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
      Speaker: Steve Caplan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 11:30 AM
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
      Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 10:30 AM
      iPSC- and patient- derived intestinal organoids for gastrointestinal research
      iPSC- and patient- derived intestinal organoids for gastrointestinal...
      Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
      Speaker: Kevin Su
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      SEP 23, 2020 | 9:00 AM
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
      Speaker: Benedetta Bussolati, MD, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
    JAN 21, 2021 | 8:00 AM
    Critical reagent characterization for regulated bioassays accelerated by Uncle
    Critical reagent characterization for regulated bioassays accelerated...
    Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
    Speaker: Ron Bowsher , Adam Kinne , Kevin Lance, Ph.D.
    Sponsored By: Unchained Labs
    6
    DEC 10, 2020 | 8:00 AM
    Simple and Fast Charge Variants Analysis of mAbs by CZE
    Simple and Fast Charge Variants Analysis of mAbs by CZE
    Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
    Speaker: Yan He, Ph.D.
    Sponsored By: SCIEX
    4 1
    DEC 09, 2020 | 8:00 AM
    Nanoscopy Meets Lifetime - Introducing the new STELLARIS 8 Ï„-STED
    Nanoscopy Meets Lifetime - Introducing the new STELLARIS 8 Ï„-STED
    Date: December 89 2020 Time: 8:00am (PST), 11:00am (EST) This talk introduces the Leica STELLARIS 8 τ-STED system where STED Nanoscopy meets Leica’s Fast Lifetime Contrast (FALCON)...
    Speaker: Julia Roberti, Ph.D.
    Sponsored By: Leica Microsystems
    1
    DEC 09, 2020 | 7:00 AM
    Characterization of RNA therapeutics from small to large
    Characterization of RNA therapeutics from small to large
    Date: December 9, 2020 Time: 7:00am (PST), 10:00am (EST) In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messen...
    Speaker: Stephen Lock, PhD
    Sponsored By: SCIEX
    5
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
     
     
  • DEC 03, 2020 | 12:00 AM
    Development, assessment and commercialization of serological SARS CoV-2 tests - an interdisciplinary success story
    Development, assessment and commercialization of serological SARS...
    Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
    Speaker: Mark Dürkop, PhD
    Presented at: Coronavirus Series
    3
    NOV 19, 2020 | 9:00 AM
    From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
    From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
    DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
    Speaker: Amal Hassan Ali
    Sponsored By: Thermo Fisher Scientific
    16 1
    NOV 19, 2020 | 8:00 AM
    From discovery to functional assays: therapeutic antibody research by Miltenyi Biotec
    From discovery to functional assays: therapeutic antibody research...
    Date: November 19, 2020 Time: 8:00am PST, 11:00am EST Monoclonal antibody-based drugs have shown great potential as a treatment for several cancers. At Miltenyi Biotec, we offer a complete wo...
    Speaker: Dr. Susanne Bethke
    Sponsored By: Miltenyi Biotec
    9
    NOV 12, 2020 | 10:00 AM
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
    Speaker: Tilman Schlothauer, Ph.D
    Sponsored By: Roche CustomBiotech
    3
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
     
     
  • OCT 21, 2020 | 12:00 AM
    Modification and Analytical Characterization of Polyol Based Polymers for Ice Recrystallization Inhibition and Thermal Hysteresis Activity
    Modification and Analytical Characterization of Polyol Based Polymers...
    Ice formation is a global issue that poses serious challenges for many applications. Certain species in colder regions of the world have adapted to that climate by producing antifreeze (glyc...
    Speaker: John G. Tsavalas, PhD
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    2
    OCT 21, 2020 | 12:00 AM
    Developing a Complete Workflow Including N-Linked Glycans Analysis for Monoclonal Antibodies with High Resolution Mass Spectrometry and Fluorescence Detection
    Developing a Complete Workflow Including N-Linked Glycans Analysis...
    Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
    Speaker: Brian Domanski
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 07, 2020 | 10:30 AM
    Immune correlates of TP53 mutational status in acute myeloid leukemia
    Immune correlates of TP53 mutational status in acute myeloid leukemia
    Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
    Speaker: Dr. Sergio Rutella
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    SEP 30, 2020 | 1:30 PM
    Harnessing novel CRISPR systems for genome engineering
    Harnessing novel CRISPR systems for genome engineering
    RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: CRISPR Virtual Event Series 2020
    4
     
     
  • SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: IDT
    2
    SEP 30, 2020 | 12:00 AM
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
    CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
    Speaker: Jonas Korlach, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
    Applying targeted long-read sequencing to assess an expanded repeat...
    A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
    Speaker: Marka van Blitterswijk, MD, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 29, 2020 | 7:00 AM
    Considerations in the Use of Analytical Ultracentrifugation for Characterization of AAV Gene Delivery Vectors
    Considerations in the Use of Analytical Ultracentrifugation for...
    Date: September 29, 2020 Time: 10:00am PTD, 1:00pm EDT alytical Ultracentrifugation (AUC) in the biopharmaceutical industry has traditionally been employed in the analysis of aggregation and...
    Speaker: Christopher Sucato
    Sponsored By: Beckman Coulter Life Sciences
    6 1
    SEP 23, 2020 | 1:30 PM
    Keynote Presentation: Starting at the source: tissue extracellular vesicles and Alzheimer's disease
    Keynote Presentation: Starting at the source: tissue extracellular...
    Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
    Speaker: Kenneth W. Witwer, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
     
     
  • SEP 23, 2020 | 12:00 PM
    Keynote Presentation: Sorting out the mechanisms of endocytic recycling
    Keynote Presentation: Sorting out the mechanisms of endocytic...
    Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
    Speaker: Steve Caplan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 11:30 AM
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
    Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 10:30 AM
    iPSC- and patient- derived intestinal organoids for gastrointestinal research
    iPSC- and patient- derived intestinal organoids for gastrointestinal...
    Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
    Speaker: Kevin Su
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    SEP 23, 2020 | 9:00 AM
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
    Speaker: Benedetta Bussolati, MD, PhD
    Presented at: Cell Biology Virtual Event Series 2020
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