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    Protein Structure

    Protein Structure: is the three-dimensional arrangement of atoms in an amino acid-chain molecule. ... Proteins form by amino acids undergoing condensation reactions, in which the amino acids lose one water molecule per reaction in order to attach to one another with a peptide bond.

    Webinars

    • SEP 22, 2020 | 10:00 AM
      Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software
      Characterization of N-linked glycans with the Released Glycans...
      Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
      Speaker: Rebecca Glaskin
      Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
      1
      SEP 17, 2020 | 3:30 PM
      Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue to defeat COVID-19?
      Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue...
      COVID-19 has developed into a crisis of global proportions. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Key to SARS-CoV-2 therapeutic development is u...
      Speaker: Imre Berger
      Presented at: Coronavirus Series
      Sponsored By: GenScript
      2
      SEP 17, 2020 | 2:00 PM
      Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
      Keynote Presentation: The formation of an International Collaborative...
      Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
      Speaker: Jacqueline Fabius , Nevan Krogan, PhD
      Presented at: Coronavirus Series
      1
      SEP 17, 2020 | 12:00 PM
      Antibody therapy against SARS-CoV-2: A Global Collaboration
      Antibody therapy against SARS-CoV-2: A Global Collaboration
      Therapeutic antibody can provide key protection or lifesaving treatment for those who haven't been or can’t be vaccinated, or when vaccines don’t “take". We galvan...
      Speaker: Erica Ollmann Saphire, PhD
      Presented at: Coronavirus Series
      2
      SEP 10, 2020 | 6:00 AM
      Structure-guided design of SARS-CoV-2 antivirals
      Structure-guided design of SARS-CoV-2 antivirals
      Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is spreading rapidly across the world and was announced as a “global pandemic” by the World Health Organization (WHO) o...
      Speaker: Quan Wang, PhD , Renhong Yan, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: Thermo Fisher Scientific
      2
      SEP 08, 2020 | 11:00 PM
      Development of Respiratory Syncytial Virus and Universal Influenza Virus Vaccines Conformationally Stabilized by Targeted Dityrosine Crosslinking
      Development of Respiratory Syncytial Virus and Universal Influenza...
      While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
      Speaker: Mark A. Yondola, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Nanoparticle-based next-generation influenza vaccines
      Nanoparticle-based next-generation influenza vaccines
      Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
      Speaker: Masaru Kanekiyo, DVM, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 12:00 PM
      Keynote Presentation: Structure-based Vaccine Design for COVID-19 and other Respiratory Viruses
      Keynote Presentation: Structure-based Vaccine Design for COVID-19...
      While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
      Speaker: Barney S. Graham, MD, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 9:00 AM
      Keynote Presentation: A Universal Influenza Virus Vaccine
      Keynote Presentation: A Universal Influenza Virus Vaccine
      Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
      Speaker: Peter Palese, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      3
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 27, 2020 | 7:00 AM
      Atlas of the SARS-CoV-2 Proteome
      Atlas of the SARS-CoV-2 Proteome
      DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
      Speaker: Yuning Chen, Ph.D.
      Sponsored By: Sino Biological
      32 3
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      AUG 06, 2020 | 10:00 AM
      Part III: Exploring the inhibition of Alk2 kinase and dimerization of EGFR kinase
      Part III: Exploring the inhibition of Alk2 kinase and dimerization...
      One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
      Speaker: Kumar Ashtekar, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Nanomaterials Engineering to Probe and Control Living Systems
      Nanomaterials Engineering to Probe and Control Living Systems
      Unique physical, chemical, and optical phenomena arise when materials are confined to the nanoscale. We are accustomed to making observations for the behavior of living systems on a macrosco...
      Speaker: Markita Landry, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 12:00 AM
      Heterogeneous ultrafast relaxation in photosynthetic light-harvesting proteins
      Heterogeneous ultrafast relaxation in photosynthetic light-harvesting...
      In photosynthesis, solar energy capture to conversion occurs with a remarkable near-unity quantum efficiency through energy transport across a network of chromophore-containing proteins. The...
      Speaker: Gabriela Schlau-Cohen, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Liquid phase Peak Force Infrared Microscopy: Super-resolution Infrared Microscopy in the Aqueous Phase
      Liquid phase Peak Force Infrared Microscopy: Super-resolution...
      Infrared spectroscopy and microscopy directly couples to molecular functional groups, providing chemical information without extrinsic labels. However, conventional infrared spectroscopy and...
      Speaker: Xiaoji Xu, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Prevalence and reactivity of fused-rubredoxin AlkBs
      Prevalence and reactivity of fused-rubredoxin AlkBs
      Over 100 distinct alkane monooxygenase (AlkB) enzymes containing a covalently bound, or fused, rubredoxin domain were identified and analyzed using bioinformatic techniques. One such protein...
      Speaker: Shoshana Williams
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      More Exquisitely Adapted Species Have Higher Structural Disorder in Vertebrate Protein Domains
      More Exquisitely Adapted Species Have Higher Structural Disorder...
      Protein structural disorder helps avoid misfolding and aggregation, but in impeding protein folding might also impede function. The balance between these two selective pressures on protein b...
      Speaker: Catherine Weibel
      Presented at: 2020 Beckman Symposium
      1
      JUL 16, 2020 | 8:00 AM
      SRRF 'n' TIRF - simultaneous spatiotemporal super-resolution and multi-parametric fluorescence microscopy
      SRRF 'n' TIRF - simultaneous spatiotemporal super-resolution and...
      DATE: July 16, 2020 TIME: 8:00am PT, 11:00am ET Super-resolution microscopy and single molecule fluorescence spectroscopy often require mutually exclusive experimental strategies optimizing...
      Speaker: Thorsten Wohland , Alan Mullan, PhD
      Sponsored By: Andor
      15
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 18, 2020 | 9:00 AM
      The Next Generation of Ion Mobility MS with Structures for Lossless Ion Manipulations
      The Next Generation of Ion Mobility MS with Structures for Lossless...
      Structures for Lossless Ion Manipulations (SLIM) is a technology that provides a means to trap and transmit ions with high efficiency over very long path lengths (up to multiple kilometers)...
      Speaker: Christian Klein, PhD , Daniel DeBord, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      2
      JUN 17, 2020 | 12:00 PM
      High-Throughput Assay for Monitoring COVID19 Antibodies and Their Isotypes
      High-Throughput Assay for Monitoring COVID19 Antibodies and Their...
      The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
      Speaker: Susan Zolla-Pazner, PhD
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 17, 2020 | 12:00 PM
      Luminex®: Flexible Solutions for SARS-CoV-2 Detection
      Luminex®: Flexible Solutions for SARS-CoV-2 Detection
      Join us and hear from two Luminex® experts on our flexible solutions for molecular diagnostics. Dr. Sherry Dunbar and Dr. Aaron Benfield will describe our NxTAG® bead-based nucleic a...
      Speaker: Aaron P. Benfield, PhD , Sherry A. Dunbar, PhD, MBA
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 17, 2020 | 11:00 AM
      Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's ExD Cell
      Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's...
      The ExD Option, available for both new and existing Agilent instruments, offers superior electron fragmentation in combination with collision induced dissociation (CID) compared to other exi...
      Speaker: Christian Klein, PhD , Joe Beckman, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      1
    SEP 22, 2020 | 10:00 AM
    Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software
    Characterization of N-linked glycans with the Released Glycans...
    Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
    Speaker: Rebecca Glaskin
    Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
    1
    SEP 17, 2020 | 3:30 PM
    Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue to defeat COVID-19?
    Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue...
    COVID-19 has developed into a crisis of global proportions. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Key to SARS-CoV-2 therapeutic development is u...
    Speaker: Imre Berger
    Presented at: Coronavirus Series
    Sponsored By: GenScript
    2
    SEP 17, 2020 | 2:00 PM
    Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
    Keynote Presentation: The formation of an International Collaborative...
    Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
    Speaker: Jacqueline Fabius , Nevan Krogan, PhD
    Presented at: Coronavirus Series
    1
    SEP 17, 2020 | 12:00 PM
    Antibody therapy against SARS-CoV-2: A Global Collaboration
    Antibody therapy against SARS-CoV-2: A Global Collaboration
    Therapeutic antibody can provide key protection or lifesaving treatment for those who haven't been or can’t be vaccinated, or when vaccines don’t “take". We galvan...
    Speaker: Erica Ollmann Saphire, PhD
    Presented at: Coronavirus Series
    2
    SEP 10, 2020 | 6:00 AM
    Structure-guided design of SARS-CoV-2 antivirals
    Structure-guided design of SARS-CoV-2 antivirals
    Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is spreading rapidly across the world and was announced as a “global pandemic” by the World Health Organization (WHO) o...
    Speaker: Quan Wang, PhD , Renhong Yan, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: Thermo Fisher Scientific
    2
     
     
  • SEP 08, 2020 | 11:00 PM
    Development of Respiratory Syncytial Virus and Universal Influenza Virus Vaccines Conformationally Stabilized by Targeted Dityrosine Crosslinking
    Development of Respiratory Syncytial Virus and Universal Influenza...
    While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
    Speaker: Mark A. Yondola, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Nanoparticle-based next-generation influenza vaccines
    Nanoparticle-based next-generation influenza vaccines
    Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
    Speaker: Masaru Kanekiyo, DVM, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 12:00 PM
    Keynote Presentation: Structure-based Vaccine Design for COVID-19 and other Respiratory Viruses
    Keynote Presentation: Structure-based Vaccine Design for COVID-19...
    While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
    Speaker: Barney S. Graham, MD, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 9:00 AM
    Keynote Presentation: A Universal Influenza Virus Vaccine
    Keynote Presentation: A Universal Influenza Virus Vaccine
    Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
    Speaker: Peter Palese, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
     
     
  • AUG 27, 2020 | 7:00 AM
    Atlas of the SARS-CoV-2 Proteome
    Atlas of the SARS-CoV-2 Proteome
    DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
    Speaker: Yuning Chen, Ph.D.
    Sponsored By: Sino Biological
    32 3
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    AUG 06, 2020 | 10:00 AM
    Part III: Exploring the inhibition of Alk2 kinase and dimerization of EGFR kinase
    Part III: Exploring the inhibition of Alk2 kinase and dimerization...
    One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
    Speaker: Kumar Ashtekar, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Nanomaterials Engineering to Probe and Control Living Systems
    Nanomaterials Engineering to Probe and Control Living Systems
    Unique physical, chemical, and optical phenomena arise when materials are confined to the nanoscale. We are accustomed to making observations for the behavior of living systems on a macrosco...
    Speaker: Markita Landry, PhD
    Presented at: 2020 Beckman Symposium
    2
    AUG 06, 2020 | 12:00 AM
    Heterogeneous ultrafast relaxation in photosynthetic light-harvesting proteins
    Heterogeneous ultrafast relaxation in photosynthetic light-harvesting...
    In photosynthesis, solar energy capture to conversion occurs with a remarkable near-unity quantum efficiency through energy transport across a network of chromophore-containing proteins. The...
    Speaker: Gabriela Schlau-Cohen, PhD
    Presented at: 2020 Beckman Symposium
    1
     
     
  • AUG 06, 2020 | 12:00 AM
    Liquid phase Peak Force Infrared Microscopy: Super-resolution Infrared Microscopy in the Aqueous Phase
    Liquid phase Peak Force Infrared Microscopy: Super-resolution...
    Infrared spectroscopy and microscopy directly couples to molecular functional groups, providing chemical information without extrinsic labels. However, conventional infrared spectroscopy and...
    Speaker: Xiaoji Xu, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Prevalence and reactivity of fused-rubredoxin AlkBs
    Prevalence and reactivity of fused-rubredoxin AlkBs
    Over 100 distinct alkane monooxygenase (AlkB) enzymes containing a covalently bound, or fused, rubredoxin domain were identified and analyzed using bioinformatic techniques. One such protein...
    Speaker: Shoshana Williams
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    More Exquisitely Adapted Species Have Higher Structural Disorder in Vertebrate Protein Domains
    More Exquisitely Adapted Species Have Higher Structural Disorder...
    Protein structural disorder helps avoid misfolding and aggregation, but in impeding protein folding might also impede function. The balance between these two selective pressures on protein b...
    Speaker: Catherine Weibel
    Presented at: 2020 Beckman Symposium
    1
    JUL 16, 2020 | 8:00 AM
    SRRF 'n' TIRF - simultaneous spatiotemporal super-resolution and multi-parametric fluorescence microscopy
    SRRF 'n' TIRF - simultaneous spatiotemporal super-resolution and...
    DATE: July 16, 2020 TIME: 8:00am PT, 11:00am ET Super-resolution microscopy and single molecule fluorescence spectroscopy often require mutually exclusive experimental strategies optimizing...
    Speaker: Thorsten Wohland , Alan Mullan, PhD
    Sponsored By: Andor
    15
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
     
     
  • JUN 18, 2020 | 9:00 AM
    The Next Generation of Ion Mobility MS with Structures for Lossless Ion Manipulations
    The Next Generation of Ion Mobility MS with Structures for Lossless...
    Structures for Lossless Ion Manipulations (SLIM) is a technology that provides a means to trap and transmit ions with high efficiency over very long path lengths (up to multiple kilometers)...
    Speaker: Christian Klein, PhD , Daniel DeBord, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    2
    JUN 17, 2020 | 12:00 PM
    High-Throughput Assay for Monitoring COVID19 Antibodies and Their Isotypes
    High-Throughput Assay for Monitoring COVID19 Antibodies and Their...
    The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
    Speaker: Susan Zolla-Pazner, PhD
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    1
    JUN 17, 2020 | 12:00 PM
    Luminex®: Flexible Solutions for SARS-CoV-2 Detection
    Luminex®: Flexible Solutions for SARS-CoV-2 Detection
    Join us and hear from two Luminex® experts on our flexible solutions for molecular diagnostics. Dr. Sherry Dunbar and Dr. Aaron Benfield will describe our NxTAG® bead-based nucleic a...
    Speaker: Aaron P. Benfield, PhD , Sherry A. Dunbar, PhD, MBA
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    1
    JUN 17, 2020 | 11:00 AM
    Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's ExD Cell
    Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's...
    The ExD Option, available for both new and existing Agilent instruments, offers superior electron fragmentation in combination with collision induced dissociation (CID) compared to other exi...
    Speaker: Christian Klein, PhD , Joe Beckman, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    1
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