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    Protein Structure

    Protein Structure: is the three-dimensional arrangement of atoms in an amino acid-chain molecule. ... Proteins form by amino acids undergoing condensation reactions, in which the amino acids lose one water molecule per reaction in order to attach to one another with a peptide bond.

    Webinars

    • JUN 11, 2020 | 10:00 AM
      Correlative (Cryo-)Microscopy for Cell Biology
      Correlative (Cryo-)Microscopy for Cell Biology
      DATE: June 11, 2020 TIME: 10:00am PT, 1:00pm ET Correlative light and electron microscopy (CLEM) enables biological discoveries by merging different microscopes and imaging modalities to stu...
      Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D.
      Sponsored By: Leica Microsystems, Alveole
      35 3
      JUN 04, 2020 | 2:00 PM
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
      In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
      Speaker: KEYNOTE: Claire Brown, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      3
      JUN 03, 2020 | 12:00 AM
      Sas- 6/Ana2 Particles (SAPs) as a new model to probe the pathway of centriole and centrosome assembly
      Sas- 6/Ana2 Particles (SAPs) as a new model to probe the pathway...
      Centriole assembly requires a small number of conserved proteins. The precise pathway of centriole assembly has been difficult to study, as the lack of any one of the core assembly proteins&...
      Speaker: Alan Wainman
      Presented at: Cell & Developmental Biology Virtual Meeting
      2
      JUN 03, 2020 | 12:00 AM
      Local and Acute Optogenetic Control of Microtubule Dynamics in Live Cells
      Local and Acute Optogenetic Control of Microtubule Dynamics in...
      Microtubules (MTs) are dynamic cytoskeleton polymers forming a polarized intracellular network that provides structural support, facilitates intracellular transport and drives chromosome seg...
      Speaker: Torsten Wittmann
      Presented at: Cell & Developmental Biology Virtual Meeting
      2
      JUN 03, 2020 | 12:00 AM
      Mining the molecular noise: fluorescence fluctuation image analysis of microscopy and super-resolution microscopy images reveals biomolecule interactions & transport maps in living cells
      Mining the molecular noise: fluorescence fluctuation image analysis...
      The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
      Speaker: Paul Wiseman, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      2
      MAY 20, 2020 | 12:00 AM
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
      Speaker: Joseph de Rutte
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 13, 2020 | 8:00 AM
      Coronavirus Disease 2019 (COVID-19):  Role of Serologic Testing in Diagnosis and Assessment of Viral Immunity
      Coronavirus Disease 2019 (COVID-19): Role of Serologic Testing...
      Provide education on COVID-19 disease and SARS-CoV-2. Review the types of tests used for the diagnosis of infectious diseases. Discuss approaches to serologic test development. Review the ki...
      Speaker: David M. Engman, MD, PhD
      29 4
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      APR 24, 2020 | 9:00 AM
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
      DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
      Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
      Sponsored By: Akoya Biosciences
      6
      APR 22, 2020 | 12:00 AM
      Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
      Long-range technologies resolve complex genomic regions overlooked...
      Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
      Speaker: Mark Ebbert, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 7:30 AM
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
      Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
      Speaker: Scott Soderling, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: CasTag Biosciences
      1 1
      MAR 11, 2020 | 3:00 PM
      PANEL: Anatomical Characterization of Neuron Cell Types in the Mouse Brain
      PANEL: Anatomical Characterization of Neuron Cell Types in the...
      Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
      Speaker: Giorgio Ascoli, PhD , Hong-Wei Dong, MD, PhD , Byungkook Lim, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 1:30 PM
      PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
      PANEL: Dissecting the circuit logics in the amygdala underlying...
      Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
      Speaker: Bo Li , Tianyi Mao , Haining Zhong
      Presented at: Neuroscience Virtual Event Series 2020
      1
      FEB 26, 2020 | 12:00 PM
      Characterizing the role of B cells in Response to Immunotherapy with the NanoString GeoMx Platform
      Characterizing the role of B cells in Response to Immunotherapy...
      Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      JAN 29, 2020 | 9:00 AM
      A case study of protein sample prep strategies for membrane proteins
      A case study of protein sample prep strategies for membrane proteins
      DATE: January 29, 2019 TIME: 9:00am PST Plasma membrane proteins are a difficult subset of proteins to solubilize, purify, quantify, and detect, largely due to the challenge of extracting th...
      Speaker: Barbara Kaboord, PhD
      Sponsored By: Thermo Fisher Scientific
      6
      DEC 10, 2019 | 8:00 AM
      Expi293: New Tools for Structural Biology and Difficult to Express Proteins
      Expi293: New Tools for Structural Biology and Difficult to Express...
      DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
      Speaker: Jon Zmuda, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      NOV 19, 2019 | 10:00 AM
      LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
      LC3-associated endocytosis: guarding against neuroinflammation...
      DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
      Speaker: Bradlee L. Heckmann, Ph.D.
      Sponsored By: Miltenyi Biotec
      6
      NOV 15, 2019 | 8:00 AM
      Exosomes and super-resolution microscopy
      Exosomes and super-resolution microscopy
      DATE: November 15, 2019TIME: 8:00am PST, 11:00am EST Exosomes are small vesicles, ranging from 30-120 nanometers in diameter, secreted from cells throughout the human body. The...
      Speaker: Ryan McNamara, PhD
      Sponsored By: ONI
      8
      NOV 06, 2019 | 1:30 PM
      Challenges towards a Universal Influenza Virus Vaccine
      Challenges towards a Universal Influenza Virus Vaccine
      Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and vaccine...
      Speaker: Peter Palese, PhD
      Presented at: Influenza Virtual Event Series 2019
      4 1
      OCT 24, 2019 | 1:30 PM
      Characterization of Biotherapeutics by Chemometric and Machine Learning Analysis of NMR Spectra
      Characterization of Biotherapeutics by Chemometric and Machine...
      With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
      Speaker: Frank Delaglio, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      4 1
      OCT 24, 2019 | 10:30 AM
      Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
      Supercritical fluid chromatography of polar biomolecules at the...
      Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
      Speaker: Raffeal Bennett, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      OCT 24, 2019 | 9:00 AM
      A Comparison of Established NMR Chemometric Methods in Biopharma
      A Comparison of Established NMR Chemometric Methods in Biopharma
      Therapeutic monoclonal antibodies are a clinically important and life-saving class of biotherapeutics used in the treatment of several previously intractable diseases. However, their developm...
      Speaker: K. Wade Elliott, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      3
      OCT 01, 2019 | 8:00 AM
      Looking under the Hood and Getting Started with the Optima AUC
      Looking under the Hood and Getting Started with the Optima AUC
      DATE: October 1, 2019TIME: 8:00am PTIn the webinar, Introduction to Characterization of Biomolecules Using Analytical Ultracentrifugation, we discussed the fundamentals of analytical...
      Speaker: Akash Bhattacharya, PhD , Ross VerHeul
      Sponsored By: Beckman Coulter Life Sciences
      4
      SEP 26, 2019 | 12:00 PM
      Understanding the Regulation of Membrane Curvature During Mating in Tetrahymena Thermophila
      Understanding the Regulation of Membrane Curvature During Mating...
      The active shaping of biological membranes is essential for a variety of cellular functions including but not limited to cell migration, cell division, organelle morphology, and cell and memb...
      Speaker: Sabrice Guerrier, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      2
    JUN 11, 2020 | 10:00 AM
    Correlative (Cryo-)Microscopy for Cell Biology
    Correlative (Cryo-)Microscopy for Cell Biology
    DATE: June 11, 2020 TIME: 10:00am PT, 1:00pm ET Correlative light and electron microscopy (CLEM) enables biological discoveries by merging different microscopes and imaging modalities to stu...
    Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D.
    Sponsored By: Leica Microsystems, Alveole
    35 3
    JUN 04, 2020 | 2:00 PM
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
    In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
    Speaker: KEYNOTE: Claire Brown, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    3
    JUN 03, 2020 | 12:00 AM
    Sas- 6/Ana2 Particles (SAPs) as a new model to probe the pathway of centriole and centrosome assembly
    Sas- 6/Ana2 Particles (SAPs) as a new model to probe the pathway...
    Centriole assembly requires a small number of conserved proteins. The precise pathway of centriole assembly has been difficult to study, as the lack of any one of the core assembly proteins&...
    Speaker: Alan Wainman
    Presented at: Cell & Developmental Biology Virtual Meeting
    2
    JUN 03, 2020 | 12:00 AM
    Local and Acute Optogenetic Control of Microtubule Dynamics in Live Cells
    Local and Acute Optogenetic Control of Microtubule Dynamics in...
    Microtubules (MTs) are dynamic cytoskeleton polymers forming a polarized intracellular network that provides structural support, facilitates intracellular transport and drives chromosome seg...
    Speaker: Torsten Wittmann
    Presented at: Cell & Developmental Biology Virtual Meeting
    2
    JUN 03, 2020 | 12:00 AM
    Mining the molecular noise: fluorescence fluctuation image analysis of microscopy and super-resolution microscopy images reveals biomolecule interactions & transport maps in living cells
    Mining the molecular noise: fluorescence fluctuation image analysis...
    The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
    Speaker: Paul Wiseman, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    2
     
     
  • MAY 20, 2020 | 12:00 AM
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
    Speaker: Joseph de Rutte
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 13, 2020 | 8:00 AM
    Coronavirus Disease 2019 (COVID-19):  Role of Serologic Testing in Diagnosis and Assessment of Viral Immunity
    Coronavirus Disease 2019 (COVID-19): Role of Serologic Testing...
    Provide education on COVID-19 disease and SARS-CoV-2. Review the types of tests used for the diagnosis of infectious diseases. Discuss approaches to serologic test development. Review the ki...
    Speaker: David M. Engman, MD, PhD
    29 4
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    APR 24, 2020 | 9:00 AM
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
    DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
    Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
    Sponsored By: Akoya Biosciences
    6
    APR 22, 2020 | 12:00 AM
    Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
    Long-range technologies resolve complex genomic regions overlooked...
    Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
    Speaker: Mark Ebbert, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • APR 21, 2020 | 7:30 AM
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
    Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
    Speaker: Scott Soderling, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: CasTag Biosciences
    1 1
    MAR 11, 2020 | 3:00 PM
    PANEL: Anatomical Characterization of Neuron Cell Types in the Mouse Brain
    PANEL: Anatomical Characterization of Neuron Cell Types in the...
    Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
    Speaker: Giorgio Ascoli, PhD , Hong-Wei Dong, MD, PhD , Byungkook Lim, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 1:30 PM
    PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
    PANEL: Dissecting the circuit logics in the amygdala underlying...
    Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
    Speaker: Bo Li , Tianyi Mao , Haining Zhong
    Presented at: Neuroscience Virtual Event Series 2020
    1
    FEB 26, 2020 | 12:00 PM
    Characterizing the role of B cells in Response to Immunotherapy with the NanoString GeoMx Platform
    Characterizing the role of B cells in Response to Immunotherapy...
    Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    JAN 29, 2020 | 9:00 AM
    A case study of protein sample prep strategies for membrane proteins
    A case study of protein sample prep strategies for membrane proteins
    DATE: January 29, 2019 TIME: 9:00am PST Plasma membrane proteins are a difficult subset of proteins to solubilize, purify, quantify, and detect, largely due to the challenge of extracting th...
    Speaker: Barbara Kaboord, PhD
    Sponsored By: Thermo Fisher Scientific
    6
     
     
  • DEC 10, 2019 | 8:00 AM
    Expi293: New Tools for Structural Biology and Difficult to Express Proteins
    Expi293: New Tools for Structural Biology and Difficult to Express...
    DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
    Speaker: Jon Zmuda, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    NOV 19, 2019 | 10:00 AM
    LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
    LC3-associated endocytosis: guarding against neuroinflammation...
    DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
    Speaker: Bradlee L. Heckmann, Ph.D.
    Sponsored By: Miltenyi Biotec
    6
    NOV 15, 2019 | 8:00 AM
    Exosomes and super-resolution microscopy
    Exosomes and super-resolution microscopy
    DATE: November 15, 2019TIME: 8:00am PST, 11:00am EST Exosomes are small vesicles, ranging from 30-120 nanometers in diameter, secreted from cells throughout the human body. The...
    Speaker: Ryan McNamara, PhD
    Sponsored By: ONI
    8
    NOV 06, 2019 | 1:30 PM
    Challenges towards a Universal Influenza Virus Vaccine
    Challenges towards a Universal Influenza Virus Vaccine
    Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and vaccine...
    Speaker: Peter Palese, PhD
    Presented at: Influenza Virtual Event Series 2019
    4 1
    OCT 24, 2019 | 1:30 PM
    Characterization of Biotherapeutics by Chemometric and Machine Learning Analysis of NMR Spectra
    Characterization of Biotherapeutics by Chemometric and Machine...
    With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
    Speaker: Frank Delaglio, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    4 1
     
     
  • OCT 24, 2019 | 10:30 AM
    Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
    Supercritical fluid chromatography of polar biomolecules at the...
    Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
    Speaker: Raffeal Bennett, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
    OCT 24, 2019 | 9:00 AM
    A Comparison of Established NMR Chemometric Methods in Biopharma
    A Comparison of Established NMR Chemometric Methods in Biopharma
    Therapeutic monoclonal antibodies are a clinically important and life-saving class of biotherapeutics used in the treatment of several previously intractable diseases. However, their developm...
    Speaker: K. Wade Elliott, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    3
    OCT 01, 2019 | 8:00 AM
    Looking under the Hood and Getting Started with the Optima AUC
    Looking under the Hood and Getting Started with the Optima AUC
    DATE: October 1, 2019TIME: 8:00am PTIn the webinar, Introduction to Characterization of Biomolecules Using Analytical Ultracentrifugation, we discussed the fundamentals of analytical...
    Speaker: Akash Bhattacharya, PhD , Ross VerHeul
    Sponsored By: Beckman Coulter Life Sciences
    4
    SEP 26, 2019 | 12:00 PM
    Understanding the Regulation of Membrane Curvature During Mating in Tetrahymena Thermophila
    Understanding the Regulation of Membrane Curvature During Mating...
    The active shaping of biological membranes is essential for a variety of cellular functions including but not limited to cell migration, cell division, organelle morphology, and cell and memb...
    Speaker: Sabrice Guerrier, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    2
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