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    RNA

    RNA, short for Ribonucleic Acid, is a molecule found in the human body that is able to form polymers and secondary structures, and can be used for various activities including decoding DNA and transferring the information to the Ribosome (tRNA), incorporation into the Ribosome (rRNA), as well as many regulatory activities concerning the expression of genes.

    Webinars

    • FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      FEB 27, 2019 | 10:30 AM
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
      An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
      Speaker: G. Thomas Caltagirone, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 26, 2019 | 9:00 AM
      Integration of Technology, Process and Quality Control: Protecting Complete Sample Chain of Custody
      Integration of Technology, Process and Quality Control: Protecting...
      DATE:  February 26, 2019TIME:   9:00am PST, 12:00pm EST In an era of increasingly high-throughput, large-scale biology, with companies, government and non-prof...
      Speaker: Andrew Brooks, Ph.D. , Shawn Levy, Ph.D. , Brad Hamilton , Fay Betsou, Ph.D
      Sponsored By: Brooks Life Sciences
      10
      NOV 28, 2018 | 7:00 AM
      Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
      Discover how single-cell RNA sequencing provides deeper insights...
      DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
      Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
      Sponsored By: Illumina, 10x Genomics
      5
      NOV 15, 2018 | 8:00 AM
      Precise Gene Editing of Human Pluripotent Stem Cells
      Precise Gene Editing of Human Pluripotent Stem Cells
      CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
      Speaker: Kris Saha
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      11
      NOV 15, 2018 | 7:00 AM
      Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
      Use of stem-cell derived endothelial cells for disease relevant...
      The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
      Speaker: Filip Roudnicky
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      8
      NOV 15, 2018 | 6:00 AM
      HDV, the most severe form of viral hepatitis.   What you need to know about it
      HDV, the most severe form of viral hepatitis. What you need...
      DATE: November 15,2018TIME:  06:00am PST, 09:00am EST, 3:00pm CET Hepatitis D virus (HDV) is a unique RNA virus that requires the hepatitis B surface antigen (HBsAg) to...
      Speaker: Valentina Svicher, PhD , Ana Avellon, PhD, MD
      Sponsored By: Diasorin
      6
      NOV 13, 2018 | 9:00 AM
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
      DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
      Speaker: Sara Busatto
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
      OCT 25, 2018 | 8:00 AM
      Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
      Disease modeling and cancer therapy in stem cell-derived 3D organoid...
      DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
      Speaker: Devanjali Dutta, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      OCT 23, 2018 | 10:00 AM
      Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud
      Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations...
      DATE: October 23, 2018TIME: 10:00am PDT, 1:00pm EDT Next-generation genomic sequencing is transforming what is known about pediatric cancer and how we treat patients. But eve...
      Speaker: Scott Newman, PhD , Clay McLeod
      Sponsored By: DNAnexus
      5
      OCT 11, 2018 | 1:30 PM
      Breast Cancer as a Global Disease: Are We Up to The Challenge?
      Breast Cancer as a Global Disease: Are We Up to The Challenge?
      As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
      Speaker: Benjamin Anderson, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      3
      OCT 11, 2018 | 1:30 PM
      Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in Cancer
      Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in...
      Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
      Speaker: Martin Hirst, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 12:00 PM
      Lung Cancer Evolution and Immune Escape
      Lung Cancer Evolution and Immune Escape
      Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
      Speaker: Nicholas McGranahan, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 03, 2018 | 12:00 PM
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
      Speaker: Dipali Sashital, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
    FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
    FEB 27, 2019 | 10:30 AM
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
    An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
    Speaker: G. Thomas Caltagirone, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 26, 2019 | 9:00 AM
    Integration of Technology, Process and Quality Control: Protecting Complete Sample Chain of Custody
    Integration of Technology, Process and Quality Control: Protecting...
    DATE:  February 26, 2019TIME:   9:00am PST, 12:00pm EST In an era of increasingly high-throughput, large-scale biology, with companies, government and non-prof...
    Speaker: Andrew Brooks, Ph.D. , Shawn Levy, Ph.D. , Brad Hamilton , Fay Betsou, Ph.D
    Sponsored By: Brooks Life Sciences
    10
    NOV 28, 2018 | 7:00 AM
    Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
    Discover how single-cell RNA sequencing provides deeper insights...
    DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
    Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
    Sponsored By: Illumina, 10x Genomics
    5
    NOV 15, 2018 | 8:00 AM
    Precise Gene Editing of Human Pluripotent Stem Cells
    Precise Gene Editing of Human Pluripotent Stem Cells
    CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
    Speaker: Kris Saha
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    11
     
     
  • NOV 15, 2018 | 7:00 AM
    Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
    Use of stem-cell derived endothelial cells for disease relevant...
    The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
    Speaker: Filip Roudnicky
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    8
    NOV 15, 2018 | 6:00 AM
    HDV, the most severe form of viral hepatitis.   What you need to know about it
    HDV, the most severe form of viral hepatitis. What you need...
    DATE: November 15,2018TIME:  06:00am PST, 09:00am EST, 3:00pm CET Hepatitis D virus (HDV) is a unique RNA virus that requires the hepatitis B surface antigen (HBsAg) to...
    Speaker: Valentina Svicher, PhD , Ana Avellon, PhD, MD
    Sponsored By: Diasorin
    6
    NOV 13, 2018 | 9:00 AM
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
    DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
    Speaker: Sara Busatto
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
    OCT 25, 2018 | 8:00 AM
    Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
    Disease modeling and cancer therapy in stem cell-derived 3D organoid...
    DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
    Speaker: Devanjali Dutta, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    OCT 23, 2018 | 10:00 AM
    Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud
    Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations...
    DATE: October 23, 2018TIME: 10:00am PDT, 1:00pm EDT Next-generation genomic sequencing is transforming what is known about pediatric cancer and how we treat patients. But eve...
    Speaker: Scott Newman, PhD , Clay McLeod
    Sponsored By: DNAnexus
    5
     
     
  • OCT 11, 2018 | 1:30 PM
    Breast Cancer as a Global Disease: Are We Up to The Challenge?
    Breast Cancer as a Global Disease: Are We Up to The Challenge?
    As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
    Speaker: Benjamin Anderson, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    3
    OCT 11, 2018 | 1:30 PM
    Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in Cancer
    Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in...
    Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
    Speaker: Martin Hirst, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 12:00 PM
    Lung Cancer Evolution and Immune Escape
    Lung Cancer Evolution and Immune Escape
    Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
    Speaker: Nicholas McGranahan, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
     
     
  • OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 03, 2018 | 12:00 PM
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
    Speaker: Dipali Sashital, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
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