Addiction: Addiction is defined as a chronic, relapsing brain disease that is characterized by compulsive drug seeking and use, despite harmful consequences. It is considered a brain disease because drugs change the brain-they change its structure and how it works. These brain changes can be long-lasting, and can lead to the harmful behaviors seen in people who abuse drugs. Addiction is a lot like other diseases, such as heart disease. Both disrupt the normal, healthy functioning of the underlying organ, have serious harmful consequences, and are preventable and treatable, but if left untreated, can last a lifetime.
Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
The Evolution of Addiction Medicine - Survive or Thrive? Franco Sicuro MD, reflecting on 30 years as board certified psychiatrist, will take you on a journey of how Addiction Medicine h...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. The ability to select appropriate behavioral responses to environmental stimuli, such as avoiding a pred...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
This presentation will include both preclinical and small clinical studies with details on mechanism of action, safety and efficacy of a candidate drug that has the capability of alleviating...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
 This webinar presents the experience gained at our laboratory with comprehensive urine drug screening for clinical research using the Thermo Scientific™ Q Exactive™ hybrid quadrupole-Orbitra...
Guidelines for physicians treating pain patients with chronic opioid therapy recommend the patients be monitored for the presence of their prescribed medications. In addition, it is often rec...
Parkinsons disease is the most common neurodegenerative movement disorder. Over the past few years, studies have identified a number of genes that cause or contribute to the pathogenesis of t...
The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
The Evolution of Addiction Medicine - Survive or Thrive? Franco Sicuro MD, reflecting on 30 years as board certified psychiatrist, will take you on a journey of how Addiction Medicine h...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. The ability to select appropriate behavioral responses to environmental stimuli, such as avoiding a pred...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
This presentation will include both preclinical and small clinical studies with details on mechanism of action, safety and efficacy of a candidate drug that has the capability of alleviating...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
 This webinar presents the experience gained at our laboratory with comprehensive urine drug screening for clinical research using the Thermo Scientific™ Q Exactive™ hybrid quadrupole-Orbitra...
Guidelines for physicians treating pain patients with chronic opioid therapy recommend the patients be monitored for the presence of their prescribed medications. In addition, it is often rec...
Parkinsons disease is the most common neurodegenerative movement disorder. Over the past few years, studies have identified a number of genes that cause or contribute to the pathogenesis of t...
The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
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