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    ALS

    ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. A-myo-trophic comes from the Greek language. "A" means no. "Myo" refers to muscle, and "Trophic" means nourishment - "No muscle nourishment."

    Webinars

    • FEB 27, 2019 | 12:00 PM
      Nanostructured Molecularly Imprinted Polymers: Robust, Stable and Selective Alternatives to Antibodies
      Nanostructured Molecularly Imprinted Polymers: Robust, Stable...
      NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
      Speaker: Adrian Kinkaid
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      FEB 27, 2019 | 12:00 PM
      Why Pain Control Is Good Science-The Scientific Rationale
      Why Pain Control Is Good Science-The Scientific Rationale
      Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
      An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
      Speaker: G. Thomas Caltagirone, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and Their Avoidance
      In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and...
      Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
      Speaker: Matthew Flegal, BS, SRS
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 8:00 AM
      Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
      Prepare for success: GMP cell banks as part of a staged, standardized,...
      DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
      Speaker: Benjamin Fryer
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
      FEB 27, 2019 | 7:30 AM
      Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
      Keynote Presentation: Second Harmonic Generation Detection of...
      Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
      Speaker: Frank McCormick, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 26, 2019 | 11:00 AM
      Osteosarcoma research
      Osteosarcoma research
      DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
      Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      FEB 26, 2019 | 9:00 AM
      Integration of Technology, Process and Quality Control: Protecting Complete Sample Chain of Custody
      Integration of Technology, Process and Quality Control: Protecting...
      DATE:  February 26, 2019TIME:   9:00am PST, 12:00pm EST In an era of increasingly high-throughput, large-scale biology, with companies, government and non-prof...
      Speaker: Andrew Brooks, Ph.D. , Shawn Levy, Ph.D. , Brad Hamilton , Fay Betsou, Ph.D
      Sponsored By: Brooks Life Sciences
      10
      FEB 14, 2019 | 1:30 PM
      Organs On a Chip:  A Revolution in Drug Development?
      Organs On a Chip: A Revolution in Drug Development?
      Pharmaceutical research and development efforts are often both inefficient and suffer from a high attrition rate of drug candidates within the clinical phase of development.  Most drug t...
      Speaker: Gorm Yoder, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 2
      FEB 14, 2019 | 9:00 AM
      Tissue Chips: Building Confidence Through Independent Experimental Testing
      Tissue Chips: Building Confidence Through Independent Experimental...
      Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by bi...
      Speaker: Ivan Rusyn, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2 1
      FEB 14, 2019 | 7:30 AM
      Keynote Presentation: A Comparative Approach to Oncology Drug Development: Integrating Canine Models
      Keynote Presentation: A Comparative Approach to Oncology Drug...
      Comparative oncology is the study of naturally-occurring cancers in pet animals (mainly dogs) to broaden and deepen our collective understanding of cancers in both companion species and human...
      Speaker: Amy LeBlanc, DVM DACVIM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      FEB 14, 2019 | 6:00 AM
      The NIH Microphysiological Systems Program
      The NIH Microphysiological Systems Program
      Approximately 30% of drugs have failed in human clinical trials due to adverse reactions despite promising pre-clinical studies, and another 60% fail due to lack of efficacy. The NIH Tissue C...
      Speaker: Danilo Tagle, PhD, M.S.
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      FEB 13, 2019 | 10:30 AM
      Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
      Accurate Clinical Concentration-Response Predictions for Cardiac...
      Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
      Speaker: Weihsueh Chiu, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 1
      FEB 13, 2019 | 9:00 AM
      Making Data Fly in Formation
      Making Data Fly in Formation
      In biomedical research, data should be treated as first-class corporate assets--they were expensive to create, they are expensive to maintain, and they have future business value. The petabyt...
      Speaker: Chuck Donnelly , Julie Morrison
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      1
      FEB 13, 2019 | 7:30 AM
      Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
      Keynote Presentation: Modernizing Drug Development Through Digital...
      Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      6
      FEB 07, 2019 | 8:00 AM
      Acceleration of Neuroscience Research Discovery by Incorporation of Large Area/Volume Microscopic Data
      Acceleration of Neuroscience Research Discovery by Incorporation...
      Date:  February 7, 2019Time:  8:00am PST, 11:00am EST Modern microscopes are becoming increasingly complex instruments enabling registration of image sets far beyon...
      Speaker: Anastas Popratiloff, MD, PhD
      Sponsored By: Leica Microsystems
      8
      FEB 05, 2019 | 9:00 AM
      Complimentary Webinar: Data Privacy and Other Clinical Data Management Challenges
      Complimentary Webinar: Data Privacy and Other Clinical Data Management...
      DATE:  February 5, 2019TIME:  9:00am PST, 12:00pm EST CloudLIMS.com is pleased to invite you to attend a complimentary webinar. The webinar focuses on the importa...
      Speaker: Marianne Henderson
      Sponsored By: CloudLIMS
      9
      JAN 31, 2019 | 7:30 AM
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      JAN 29, 2019 | 9:00 AM
      Targeting prostate cancer stem cells with T cell immunotherapy
      Targeting prostate cancer stem cells with T cell immunotherapy
      DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
      Speaker: Amy Codd
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      JAN 29, 2019 | 8:00 AM
      Knock out biologic quant and quality on a tiny sample
      Knock out biologic quant and quality on a tiny sample
      DATE:   January 29, 2019TIME:    08:00am PSTCollecting quantification and characterization data of biologics often requires a large amount of protein and mult...
      Speaker: Lisa Adamiak, PhD
      Sponsored By: Unchained Labs
      4
      JAN 24, 2019 | 10:00 AM
      A Clinical Perspective on Sexually Transmitted Infections: What is the State of Play
      A Clinical Perspective on Sexually Transmitted Infections: What...
      DATE: January 24, 2019TIME: 10:00am PSTSexually transmitted infections (STIs) continue to affect most sexually active populations globally, especially the traditional high-risk groups f...
      Speaker: Dr. John White
      Sponsored By: Abbott Molecular Diagnostic
      8 1
      JAN 16, 2019 | 9:00 AM
      Predicting Response to Intravesical Immunotherapy with BCG
      Predicting Response to Intravesical Immunotherapy with BCG
      DATE:  January 16th, 2019TIME:  9:00AM PDT, 12:00PM EDTDr. Kamat will present his clinical experience using molecular markers, in addition to the standard of care,to examine pat...
      Speaker: Ashish Kamat, MD, MBBS
      Sponsored By: Abbott Molecular Diagnostic
      3 1
      JAN 15, 2019 | 8:00 AM
      C.E. CREDITS
      Hemostasis lab quality best practices; focus on validation of assays and instrumentation in a multisite hospital system
      Hemostasis lab quality best practices; focus on validation of...
      Learn best practices for validating coagulation testing instruments, ensuring quality results, and managing challenges across hospital networks....
      Speaker: Jana Gausman, MT (ASCP)
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      11
    FEB 27, 2019 | 12:00 PM
    Nanostructured Molecularly Imprinted Polymers: Robust, Stable and Selective Alternatives to Antibodies
    Nanostructured Molecularly Imprinted Polymers: Robust, Stable...
    NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
    Speaker: Adrian Kinkaid
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    FEB 27, 2019 | 12:00 PM
    Why Pain Control Is Good Science-The Scientific Rationale
    Why Pain Control Is Good Science-The Scientific Rationale
    Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
    An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
    Speaker: G. Thomas Caltagirone, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and Their Avoidance
    In Vivo Surgical Models for Drug Discovery: Hidden Pitfalls and...
    Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
    Speaker: Matthew Flegal, BS, SRS
    Presented at: Drug Discovery Virtual Event Series 2019
    2
     
     
  • FEB 27, 2019 | 8:00 AM
    Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
    Prepare for success: GMP cell banks as part of a staged, standardized,...
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    Speaker: Benjamin Fryer
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
    FEB 27, 2019 | 7:30 AM
    Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
    Keynote Presentation: Second Harmonic Generation Detection of...
    Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
    Speaker: Frank McCormick, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 26, 2019 | 11:00 AM
    Osteosarcoma research
    Osteosarcoma research
    DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
    Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    FEB 26, 2019 | 9:00 AM
    Integration of Technology, Process and Quality Control: Protecting Complete Sample Chain of Custody
    Integration of Technology, Process and Quality Control: Protecting...
    DATE:  February 26, 2019TIME:   9:00am PST, 12:00pm EST In an era of increasingly high-throughput, large-scale biology, with companies, government and non-prof...
    Speaker: Andrew Brooks, Ph.D. , Shawn Levy, Ph.D. , Brad Hamilton , Fay Betsou, Ph.D
    Sponsored By: Brooks Life Sciences
    10
    FEB 14, 2019 | 1:30 PM
    Organs On a Chip:  A Revolution in Drug Development?
    Organs On a Chip: A Revolution in Drug Development?
    Pharmaceutical research and development efforts are often both inefficient and suffer from a high attrition rate of drug candidates within the clinical phase of development.  Most drug t...
    Speaker: Gorm Yoder, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 2
     
     
  • FEB 14, 2019 | 9:00 AM
    Tissue Chips: Building Confidence Through Independent Experimental Testing
    Tissue Chips: Building Confidence Through Independent Experimental...
    Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by bi...
    Speaker: Ivan Rusyn, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2 1
    FEB 14, 2019 | 7:30 AM
    Keynote Presentation: A Comparative Approach to Oncology Drug Development: Integrating Canine Models
    Keynote Presentation: A Comparative Approach to Oncology Drug...
    Comparative oncology is the study of naturally-occurring cancers in pet animals (mainly dogs) to broaden and deepen our collective understanding of cancers in both companion species and human...
    Speaker: Amy LeBlanc, DVM DACVIM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
    FEB 14, 2019 | 6:00 AM
    The NIH Microphysiological Systems Program
    The NIH Microphysiological Systems Program
    Approximately 30% of drugs have failed in human clinical trials due to adverse reactions despite promising pre-clinical studies, and another 60% fail due to lack of efficacy. The NIH Tissue C...
    Speaker: Danilo Tagle, PhD, M.S.
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
    FEB 13, 2019 | 10:30 AM
    Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
    Accurate Clinical Concentration-Response Predictions for Cardiac...
    Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
    Speaker: Weihsueh Chiu, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 1
    FEB 13, 2019 | 9:00 AM
    Making Data Fly in Formation
    Making Data Fly in Formation
    In biomedical research, data should be treated as first-class corporate assets--they were expensive to create, they are expensive to maintain, and they have future business value. The petabyt...
    Speaker: Chuck Donnelly , Julie Morrison
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    1
     
     
  • FEB 13, 2019 | 7:30 AM
    Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
    Keynote Presentation: Modernizing Drug Development Through Digital...
    Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    6
    FEB 07, 2019 | 8:00 AM
    Acceleration of Neuroscience Research Discovery by Incorporation of Large Area/Volume Microscopic Data
    Acceleration of Neuroscience Research Discovery by Incorporation...
    Date:  February 7, 2019Time:  8:00am PST, 11:00am EST Modern microscopes are becoming increasingly complex instruments enabling registration of image sets far beyon...
    Speaker: Anastas Popratiloff, MD, PhD
    Sponsored By: Leica Microsystems
    8
    FEB 05, 2019 | 9:00 AM
    Complimentary Webinar: Data Privacy and Other Clinical Data Management Challenges
    Complimentary Webinar: Data Privacy and Other Clinical Data Management...
    DATE:  February 5, 2019TIME:  9:00am PST, 12:00pm EST CloudLIMS.com is pleased to invite you to attend a complimentary webinar. The webinar focuses on the importa...
    Speaker: Marianne Henderson
    Sponsored By: CloudLIMS
    9
    JAN 31, 2019 | 7:30 AM
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    JAN 29, 2019 | 9:00 AM
    Targeting prostate cancer stem cells with T cell immunotherapy
    Targeting prostate cancer stem cells with T cell immunotherapy
    DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
    Speaker: Amy Codd
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
     
     
  • JAN 29, 2019 | 8:00 AM
    Knock out biologic quant and quality on a tiny sample
    Knock out biologic quant and quality on a tiny sample
    DATE:   January 29, 2019TIME:    08:00am PSTCollecting quantification and characterization data of biologics often requires a large amount of protein and mult...
    Speaker: Lisa Adamiak, PhD
    Sponsored By: Unchained Labs
    4
    JAN 24, 2019 | 10:00 AM
    A Clinical Perspective on Sexually Transmitted Infections: What is the State of Play
    A Clinical Perspective on Sexually Transmitted Infections: What...
    DATE: January 24, 2019TIME: 10:00am PSTSexually transmitted infections (STIs) continue to affect most sexually active populations globally, especially the traditional high-risk groups f...
    Speaker: Dr. John White
    Sponsored By: Abbott Molecular Diagnostic
    8 1
    JAN 16, 2019 | 9:00 AM
    Predicting Response to Intravesical Immunotherapy with BCG
    Predicting Response to Intravesical Immunotherapy with BCG
    DATE:  January 16th, 2019TIME:  9:00AM PDT, 12:00PM EDTDr. Kamat will present his clinical experience using molecular markers, in addition to the standard of care,to examine pat...
    Speaker: Ashish Kamat, MD, MBBS
    Sponsored By: Abbott Molecular Diagnostic
    3 1
    JAN 15, 2019 | 8:00 AM
    C.E. CREDITS
    Hemostasis lab quality best practices; focus on validation of assays and instrumentation in a multisite hospital system
    Hemostasis lab quality best practices; focus on validation of...
    Learn best practices for validating coagulation testing instruments, ensuring quality results, and managing challenges across hospital networks....
    Speaker: Jana Gausman, MT (ASCP)
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
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