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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • SEP 13, 2017 | 9:00 AM
      Insights into virus replication: the role of co-opted host proteins and lipids
      Insights into virus replication: the role of co-opted host proteins...
      Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
      Speaker: Peter L. Nagy, MD., PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      3
      SEP 13, 2017 | 7:30 AM
      Keynote Presentation: Using phage to select for evolution of reduced virulence in pathogenic bacteria
      Keynote Presentation: Using phage to select for evolution of reduced...
      Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies.  Ideally, new approaches would target bacterial pat...
      Speaker: Paul Turner, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      1
      SEP 13, 2017 | 6:00 AM
      Next-generation probiotics targeting C. difficile infection
      Next-generation probiotics targeting C. difficile infection
      Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
      Speaker: Jennifer Spinler, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      1
      SEP 06, 2017 | 9:00 AM
      WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
      WEBINAR: Manufacturing and characterization of therapeutic exosomes...
      DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
      Speaker: Travis Antes, PhD
      Sponsored By: Miltenyi Biotec
      9
      AUG 30, 2017 | 10:00 AM
      WEBINAR: Understanding cell reprogramming in treatment-resistant prostate cancer using organoids
      WEBINAR: Understanding cell reprogramming in treatment-resistant...
      DATE: August 30, 2017TIME: 10:00am PT, 1:00pm ETRecent studies show that cancer cells can resist treatment by changing into a different cell type. Many treatments for specific cancers,...
      Speaker: Kristine Wadosky, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 2
      AUG 01, 2017 | 12:00 AM
      Accelerating cures for rare childhood diseases using iPSC models
      Accelerating cures for rare childhood diseases using iPSC models
      Creating inducible Pluripotent Stem Cell (iPSC) collections of rare patients scattered world-wide can lower the barrier of biological discovery of rare disease, provide a platform for potenti...
      Speaker: Christina Waters
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      JUL 25, 2017 | 9:00 AM
      WEBINAR: Functional Genomics and Drug Metabolism
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      7 1
      JUL 01, 2017 | 8:00 AM
      Mechanisms for Assembling and Resolving Naïve Pluripotency
      Mechanisms for Assembling and Resolving Naïve Pluripotency
      The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
      Speaker: Jacob Hanna
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      JUL 01, 2017 | 8:00 AM
      Industry uses of human pluripotent stem cells
      Industry uses of human pluripotent stem cells
      Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
      Speaker: Stuart Chambers
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Braingineering's human midbrain organoids as novel model for neurodegenerative diseases
      Braingineering's human midbrain organoids as novel model for neurodegenerative...
      Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
      Speaker: Jens Schwamborn
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Patient-specific hiPSCs for understanding diabetes disease mechanisms
      Patient-specific hiPSCs for understanding diabetes disease mechanisms
      Diabetes is a debilitating chronic disease that is spirally out of control. Fundamentally, the progressive failure of pancreatic beta cells results in decreased insulin secretion, ultimately ...
      Speaker: Adrian Teo
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUL 01, 2017 | 8:00 AM
      iPSC-derived neural cells for drug discovery of mitochondrial brain diseases
      iPSC-derived neural cells for drug discovery of mitochondrial...
      Mitochondrial defects represent a common pathogenetic mechanism associated with neurodegeneration. At the same time, mitochondrial DNA (mtDNA) mutations frequently cause neurological diseases...
      Speaker: Alessandro Prigione
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Pancreatic progenitors: From the organ to the plate
      Pancreatic progenitors: From the organ to the plate
      Ductal cells share several markers with pancreatic embryonic progenitors, suggesting that ductal cells could be the closest lineage to an adult progenitor in the pancreas, thus their stem-lik...
      Speaker: Meritxell Rovira
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 8:00 AM
      Custom-tailored cardiomyocytes: Directed differentiation of human pluripotent stem cells into defined atrial and ventricular cardiomyocyte subtypes
      Custom-tailored cardiomyocytes: Directed differentiation of human...
      Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
      Speaker: Lukas Cyganek
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 12:00 AM
      Pluripotent stem cells to explore mechanisms and treatments of neuromuscular diseases
      Pluripotent stem cells to explore mechanisms and treatments of...
      Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
      Speaker: Cécile Martinat
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 12:00 AM
      New Tools for improved CRISPR gene-editing in stem cells
      New Tools for improved CRISPR gene-editing in stem cells
      The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
      Speaker: James Kehler VMD, PhD
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 12:00 AM
      Physiological Oxygen: Historical and Molecular Perspective for Stem Cell Culture
      Physiological Oxygen: Historical and Molecular Perspective for...
      For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
      Speaker: Mary Kay Bates, M.S.
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      JUL 01, 2017 | 12:00 AM
      Improvements in building in vitro pluripotent stem cell-derived disease models
      Improvements in building in vitro pluripotent stem cell-derived...
      The discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the genome and can be exploited to introduce changes to mimic diseases. This pre...
      Speaker: Erik Willems, PhD
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUN 13, 2017 | 9:00 AM
      WEBINAR: High content imaging and analysis for drug discovery: phenotypic assays, instrumentation and software
      WEBINAR: High content imaging and analysis for drug discovery:...
      EVENT DETAILS: DATE: June 13, 2017TIME: 9:00am PT, 12:00pm ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in...
      Speaker: Nicholas Dolman, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      3
      JUN 08, 2017 | 12:00 PM
      Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing the Latest Technologies from Thermo Fisher Scientific
      Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing...
      The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
      Speaker: Rhonda Newman, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUN 07, 2017 | 9:00 AM
      WEBINAR: Generation of purified human iPSC derived cardiomyocytes using clinically relevant workflow
      WEBINAR: Generation of purified human iPSC derived cardiomyocytes...
      DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
      Speaker: Todd Herron, BS, PhD
      Sponsored By: Miltenyi Biotec
      5 1
      MAY 25, 2017 | 10:30 AM
      Open Targets Platform: mining gene and disease evidence for improved drug target selection.
      Open Targets Platform: mining gene and disease evidence for improved...
      Open Targets is a public-private partnership made up of four global leading institutions in the fields of pharmaceuticals, bioinformatics and genomics, GSK, EMBL-EBI, the Wellcome Trust Sange...
      Speaker: Denise Carvalho-Silva
      Presented at: Lab Automation Virtual Event Series 2017
      1
      MAY 17, 2017 | 10:30 AM
      WEBINAR: Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOneâ„¢ Supplement
      WEBINAR: Improved differentiation of stem cell-derived neurons...
      DATE: May 17, 2017TIME: 10:30am PT, 1:30pm ETNeurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and d...
      Speaker: David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
    SEP 13, 2017 | 9:00 AM
    Insights into virus replication: the role of co-opted host proteins and lipids
    Insights into virus replication: the role of co-opted host proteins...
    Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
    Speaker: Peter L. Nagy, MD., PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    3
    SEP 13, 2017 | 7:30 AM
    Keynote Presentation: Using phage to select for evolution of reduced virulence in pathogenic bacteria
    Keynote Presentation: Using phage to select for evolution of reduced...
    Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies.  Ideally, new approaches would target bacterial pat...
    Speaker: Paul Turner, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    1
    SEP 13, 2017 | 6:00 AM
    Next-generation probiotics targeting C. difficile infection
    Next-generation probiotics targeting C. difficile infection
    Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
    Speaker: Jennifer Spinler, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    1
    SEP 06, 2017 | 9:00 AM
    WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
    WEBINAR: Manufacturing and characterization of therapeutic exosomes...
    DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
    Speaker: Travis Antes, PhD
    Sponsored By: Miltenyi Biotec
    9
    AUG 30, 2017 | 10:00 AM
    WEBINAR: Understanding cell reprogramming in treatment-resistant prostate cancer using organoids
    WEBINAR: Understanding cell reprogramming in treatment-resistant...
    DATE: August 30, 2017TIME: 10:00am PT, 1:00pm ETRecent studies show that cancer cells can resist treatment by changing into a different cell type. Many treatments for specific cancers,...
    Speaker: Kristine Wadosky, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 2
     
     
  • AUG 01, 2017 | 12:00 AM
    Accelerating cures for rare childhood diseases using iPSC models
    Accelerating cures for rare childhood diseases using iPSC models
    Creating inducible Pluripotent Stem Cell (iPSC) collections of rare patients scattered world-wide can lower the barrier of biological discovery of rare disease, provide a platform for potenti...
    Speaker: Christina Waters
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    JUL 25, 2017 | 9:00 AM
    WEBINAR: Functional Genomics and Drug Metabolism
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
    7 1
    JUL 01, 2017 | 8:00 AM
    Mechanisms for Assembling and Resolving Naïve Pluripotency
    Mechanisms for Assembling and Resolving Naïve Pluripotency
    The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
    Speaker: Jacob Hanna
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
    JUL 01, 2017 | 8:00 AM
    Industry uses of human pluripotent stem cells
    Industry uses of human pluripotent stem cells
    Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
    Speaker: Stuart Chambers
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUL 01, 2017 | 8:00 AM
    Braingineering's human midbrain organoids as novel model for neurodegenerative diseases
    Braingineering's human midbrain organoids as novel model for neurodegenerative...
    Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
    Speaker: Jens Schwamborn
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
     
     
  • JUL 01, 2017 | 8:00 AM
    Patient-specific hiPSCs for understanding diabetes disease mechanisms
    Patient-specific hiPSCs for understanding diabetes disease mechanisms
    Diabetes is a debilitating chronic disease that is spirally out of control. Fundamentally, the progressive failure of pancreatic beta cells results in decreased insulin secretion, ultimately ...
    Speaker: Adrian Teo
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    JUL 01, 2017 | 8:00 AM
    iPSC-derived neural cells for drug discovery of mitochondrial brain diseases
    iPSC-derived neural cells for drug discovery of mitochondrial...
    Mitochondrial defects represent a common pathogenetic mechanism associated with neurodegeneration. At the same time, mitochondrial DNA (mtDNA) mutations frequently cause neurological diseases...
    Speaker: Alessandro Prigione
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUL 01, 2017 | 8:00 AM
    Pancreatic progenitors: From the organ to the plate
    Pancreatic progenitors: From the organ to the plate
    Ductal cells share several markers with pancreatic embryonic progenitors, suggesting that ductal cells could be the closest lineage to an adult progenitor in the pancreas, thus their stem-lik...
    Speaker: Meritxell Rovira
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUL 01, 2017 | 8:00 AM
    Custom-tailored cardiomyocytes: Directed differentiation of human pluripotent stem cells into defined atrial and ventricular cardiomyocyte subtypes
    Custom-tailored cardiomyocytes: Directed differentiation of human...
    Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
    Speaker: Lukas Cyganek
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUL 01, 2017 | 12:00 AM
    Pluripotent stem cells to explore mechanisms and treatments of neuromuscular diseases
    Pluripotent stem cells to explore mechanisms and treatments of...
    Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
    Speaker: Cécile Martinat
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
     
     
  • JUL 01, 2017 | 12:00 AM
    New Tools for improved CRISPR gene-editing in stem cells
    New Tools for improved CRISPR gene-editing in stem cells
    The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
    Speaker: James Kehler VMD, PhD
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUL 01, 2017 | 12:00 AM
    Physiological Oxygen: Historical and Molecular Perspective for Stem Cell Culture
    Physiological Oxygen: Historical and Molecular Perspective for...
    For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
    Speaker: Mary Kay Bates, M.S.
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    JUL 01, 2017 | 12:00 AM
    Improvements in building in vitro pluripotent stem cell-derived disease models
    Improvements in building in vitro pluripotent stem cell-derived...
    The discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the genome and can be exploited to introduce changes to mimic diseases. This pre...
    Speaker: Erik Willems, PhD
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUN 13, 2017 | 9:00 AM
    WEBINAR: High content imaging and analysis for drug discovery: phenotypic assays, instrumentation and software
    WEBINAR: High content imaging and analysis for drug discovery:...
    EVENT DETAILS: DATE: June 13, 2017TIME: 9:00am PT, 12:00pm ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in...
    Speaker: Nicholas Dolman, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    3
    JUN 08, 2017 | 12:00 PM
    Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing the Latest Technologies from Thermo Fisher Scientific
    Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing...
    The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
    Speaker: Rhonda Newman, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
     
     
  • JUN 07, 2017 | 9:00 AM
    WEBINAR: Generation of purified human iPSC derived cardiomyocytes using clinically relevant workflow
    WEBINAR: Generation of purified human iPSC derived cardiomyocytes...
    DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
    Speaker: Todd Herron, BS, PhD
    Sponsored By: Miltenyi Biotec
    5 1
    MAY 25, 2017 | 10:30 AM
    Open Targets Platform: mining gene and disease evidence for improved drug target selection.
    Open Targets Platform: mining gene and disease evidence for improved...
    Open Targets is a public-private partnership made up of four global leading institutions in the fields of pharmaceuticals, bioinformatics and genomics, GSK, EMBL-EBI, the Wellcome Trust Sange...
    Speaker: Denise Carvalho-Silva
    Presented at: Lab Automation Virtual Event Series 2017
    1
    MAY 17, 2017 | 10:30 AM
    WEBINAR: Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOneâ„¢ Supplement
    WEBINAR: Improved differentiation of stem cell-derived neurons...
    DATE: May 17, 2017TIME: 10:30am PT, 1:30pm ETNeurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and d...
    Speaker: David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
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