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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • APR 07, 2021 | 12:00 AM
      Anti-fibrotic materials for immunoprotected cell-based therapies
      Anti-fibrotic materials for immunoprotected cell-based therapies
      Cell encapsulation within semi-permeable devices represents a local immunoisolation strategy for cell-based therapies without the need for systemic immunosuppression. The encapsulation syste...
      Speaker: Dr. Matthew Bochenek, PhD
      Presented at: Bioprocessing Virtual Event Series 2021
      1
      MAR 23, 2021 | 9:00 AM
      Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
      Targeted degradation of the enhancer lysine acetyltransferases...
      Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
      Speaker: Christopher Ott, PhD , Tim Geiger, PhD
      Sponsored By: ACD - A Bio-Techne Brand
      8
      FEB 04, 2021 | 8:00 AM
      Automation of organoid assays requiring a 3D Matrix with dragonfly® discovery
      Automation of organoid assays requiring a 3D Matrix with dragonfly®...
      Date: February 4, 2021 Time: 8:00am (PST), 11:00am (EST) Over the last several years, there has been increased interest around the use of patient derived organoids for personalized medicine...
      Speaker: Hilary Sherman
      Sponsored By: SPT Labtech
      8
      FEB 03, 2021 | 12:30 PM
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
      Speaker: Arvonn Tully , Judi Wardwell-Swanson
      Presented at: 7th Annual Conference: SBI2 High Content
      Sponsored By: SBI2, InSphero , Yokogawa
      11 10
      DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      DEC 03, 2020 | 10:00 AM
      Keynote Presentation: COVID-19 Projections for the United States
      Keynote Presentation: COVID-19 Projections for the United States
      Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
      Speaker: Ali H. Mokdad, PhD
      Presented at: Coronavirus Series
      2
      DEC 03, 2020 | 9:00 AM
      Transmission Dynamics of SARS-CoV-2: Inference and Projection
      Transmission Dynamics of SARS-CoV-2: Inference and Projection
      Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
      Speaker: Jeffrey Shaman
      Presented at: Coronavirus Series
      3
      DEC 02, 2020 | 9:00 AM
      Pluripotent stem cell research: fundamentals of cultivation and differentiation
      Pluripotent stem cell research: fundamentals of cultivation and...
      DATE: December 2, 2020 TIME: 9:00am PDT Pluripotent stem cell (PSC) research is a continuously evolving field that beholds great promises for the future. The great application potential of P...
      Speaker: Dr. Viola Stella Palladino
      Sponsored By: Miltenyi Biotec
      18
      NOV 19, 2020 | 9:00 AM
      From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
      From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
      DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
      Speaker: Amal Hassan Ali
      Sponsored By: Thermo Fisher Scientific
      16 1
      NOV 18, 2020 | 8:00 AM
      Whole-organ mapping using AI and light sheet microscopy
      Whole-organ mapping using AI and light sheet microscopy
      DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
      Speaker: Ali Ertürk
      Sponsored By: Miltenyi Biotec
      14
      NOV 17, 2020 | 8:00 AM
      Key Features of Immune Cells During SARS-CoV2 Infection
      Key Features of Immune Cells During SARS-CoV2 Infection
      Date: November 17, 2020 Time: 8:00am COVID-19 is a complex pathological condition caused by infection with SARS-CoV. Different features have been observed in patients with a severe dis...
      Speaker: Sara De Biasi
      Sponsored By: Thermo Fisher Scientific
      13
      NOV 12, 2020 | 8:00 AM
      Biomedical Applications of Raman Spectroscopy
      Biomedical Applications of Raman Spectroscopy
      Date: November 12, 2020 Time: 8:00am (PST), 11:00am (EST) Vaccine development, disease diagnosis and early medical intervention are all supported by Raman spectroscopy. This tool provides ri...
      Speaker: Kristen Frano , Adam Hopkins, Ph.D
      Sponsored By: Metrohm USA
      11
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 05, 2020 | 9:00 AM
      Cell-based Assays to Functionally Characterize Immunotherapy and the Immune Response to Viral Infection
      Cell-based Assays to Functionally Characterize Immunotherapy and...
      DATE: November 5, 2020 TIME: 9:00am (PDT), 12:00pm (EDT) With accelerating development and approval of cell therapies, biologic drugs, and antiviral treatments comes a need for more robust a...
      Speaker: Chris Langsdorf
      Sponsored By: Thermo Fisher Scientific
      8 1
      NOV 05, 2020 | 12:00 AM
      Stigma and Substance Use: Evidence and Myths
      Stigma and Substance Use: Evidence and Myths
      Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
      Speaker: Thomas S. Franko, PharmD, BCACP
      Presented at: Opioid Crisis Virtual Event Series 2020
      2
      OCT 15, 2020 | 9:00 AM
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
      Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
      Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
      Sponsored By: Emulate
      9
      OCT 13, 2020 | 2:30 PM
      Panel Discussion: Cancer Care in different regions and what are the current standard of care in Lung cancer
      Panel Discussion: Cancer Care in different regions and what are...
      ...
      Speaker: Arjun Khanna , David Chi Leung Lam, MD, PhD , Chein-Feng Li, MD , Darren Wan Teck Lim
      Presented at: 10 Million Reasons to Defeat Cancer - 2020 Abbott World Summit
      1
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 08, 2020 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      33 5
      OCT 08, 2020 | 6:00 AM
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
      Speaker: Christian Regenbrecht, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Luminex - A DiaSorin Company
      1
      OCT 08, 2020 | 12:00 AM
      Getting Under the Hood of Racial Disparities in Prostate Cancer
      Getting Under the Hood of Racial Disparities in Prostate Cancer
      Learning Objectives: 1. Understand the evolving epidemiology of prostate cancer in the the US and globally, and the excess burden of disease borne by men of African ancestry 2. Describe the...
      Speaker: Matthew R. Cooperberg, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 01, 2020 | 10:00 AM
      Improvements to Bile Collection Studies in Rats
      Improvements to Bile Collection Studies in Rats
      Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
      Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
      Sponsored By: SAI Infusion Technologies
      5 3
      SEP 23, 2020 | 10:30 AM
      iPSC- and patient- derived intestinal organoids for gastrointestinal research
      iPSC- and patient- derived intestinal organoids for gastrointestinal...
      Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
      Speaker: Kevin Su
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      SEP 23, 2020 | 12:00 AM
      Extracellular Vesicles and Chronic Kidney Disease
      Extracellular Vesicles and Chronic Kidney Disease
      Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
      Speaker: Sargis Sedrakyan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
    APR 07, 2021 | 12:00 AM
    Anti-fibrotic materials for immunoprotected cell-based therapies
    Anti-fibrotic materials for immunoprotected cell-based therapies
    Cell encapsulation within semi-permeable devices represents a local immunoisolation strategy for cell-based therapies without the need for systemic immunosuppression. The encapsulation syste...
    Speaker: Dr. Matthew Bochenek, PhD
    Presented at: Bioprocessing Virtual Event Series 2021
    1
    MAR 23, 2021 | 9:00 AM
    Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
    Targeted degradation of the enhancer lysine acetyltransferases...
    Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
    Speaker: Christopher Ott, PhD , Tim Geiger, PhD
    Sponsored By: ACD - A Bio-Techne Brand
    8
    FEB 04, 2021 | 8:00 AM
    Automation of organoid assays requiring a 3D Matrix with dragonfly® discovery
    Automation of organoid assays requiring a 3D Matrix with dragonfly®...
    Date: February 4, 2021 Time: 8:00am (PST), 11:00am (EST) Over the last several years, there has been increased interest around the use of patient derived organoids for personalized medicine...
    Speaker: Hilary Sherman
    Sponsored By: SPT Labtech
    8
    FEB 03, 2021 | 12:30 PM
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
    Speaker: Arvonn Tully , Judi Wardwell-Swanson
    Presented at: 7th Annual Conference: SBI2 High Content
    Sponsored By: SBI2, InSphero , Yokogawa
    11 10
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
     
     
  • DEC 03, 2020 | 10:00 AM
    Keynote Presentation: COVID-19 Projections for the United States
    Keynote Presentation: COVID-19 Projections for the United States
    Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
    Speaker: Ali H. Mokdad, PhD
    Presented at: Coronavirus Series
    2
    DEC 03, 2020 | 9:00 AM
    Transmission Dynamics of SARS-CoV-2: Inference and Projection
    Transmission Dynamics of SARS-CoV-2: Inference and Projection
    Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
    Speaker: Jeffrey Shaman
    Presented at: Coronavirus Series
    3
    DEC 02, 2020 | 9:00 AM
    Pluripotent stem cell research: fundamentals of cultivation and differentiation
    Pluripotent stem cell research: fundamentals of cultivation and...
    DATE: December 2, 2020 TIME: 9:00am PDT Pluripotent stem cell (PSC) research is a continuously evolving field that beholds great promises for the future. The great application potential of P...
    Speaker: Dr. Viola Stella Palladino
    Sponsored By: Miltenyi Biotec
    18
    NOV 19, 2020 | 9:00 AM
    From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
    From Protein Structures to Drug Discovery: Novel therapeutic opportunities.
    DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
    Speaker: Amal Hassan Ali
    Sponsored By: Thermo Fisher Scientific
    16 1
    NOV 18, 2020 | 8:00 AM
    Whole-organ mapping using AI and light sheet microscopy
    Whole-organ mapping using AI and light sheet microscopy
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    Speaker: Ali Ertürk
    Sponsored By: Miltenyi Biotec
    14
     
     
  • NOV 17, 2020 | 8:00 AM
    Key Features of Immune Cells During SARS-CoV2 Infection
    Key Features of Immune Cells During SARS-CoV2 Infection
    Date: November 17, 2020 Time: 8:00am COVID-19 is a complex pathological condition caused by infection with SARS-CoV. Different features have been observed in patients with a severe dis...
    Speaker: Sara De Biasi
    Sponsored By: Thermo Fisher Scientific
    13
    NOV 12, 2020 | 8:00 AM
    Biomedical Applications of Raman Spectroscopy
    Biomedical Applications of Raman Spectroscopy
    Date: November 12, 2020 Time: 8:00am (PST), 11:00am (EST) Vaccine development, disease diagnosis and early medical intervention are all supported by Raman spectroscopy. This tool provides ri...
    Speaker: Kristen Frano , Adam Hopkins, Ph.D
    Sponsored By: Metrohm USA
    11
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 05, 2020 | 9:00 AM
    Cell-based Assays to Functionally Characterize Immunotherapy and the Immune Response to Viral Infection
    Cell-based Assays to Functionally Characterize Immunotherapy and...
    DATE: November 5, 2020 TIME: 9:00am (PDT), 12:00pm (EDT) With accelerating development and approval of cell therapies, biologic drugs, and antiviral treatments comes a need for more robust a...
    Speaker: Chris Langsdorf
    Sponsored By: Thermo Fisher Scientific
    8 1
    NOV 05, 2020 | 12:00 AM
    Stigma and Substance Use: Evidence and Myths
    Stigma and Substance Use: Evidence and Myths
    Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
    Speaker: Thomas S. Franko, PharmD, BCACP
    Presented at: Opioid Crisis Virtual Event Series 2020
    2
     
     
  • OCT 15, 2020 | 9:00 AM
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
    Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
    Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
    Sponsored By: Emulate
    9
    OCT 13, 2020 | 2:30 PM
    Panel Discussion: Cancer Care in different regions and what are the current standard of care in Lung cancer
    Panel Discussion: Cancer Care in different regions and what are...
    ...
    Speaker: Arjun Khanna , David Chi Leung Lam, MD, PhD , Chein-Feng Li, MD , Darren Wan Teck Lim
    Presented at: 10 Million Reasons to Defeat Cancer - 2020 Abbott World Summit
    1
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 08, 2020 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    33 5
    OCT 08, 2020 | 6:00 AM
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
    Speaker: Christian Regenbrecht, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Luminex - A DiaSorin Company
    1
     
     
  • OCT 08, 2020 | 12:00 AM
    Getting Under the Hood of Racial Disparities in Prostate Cancer
    Getting Under the Hood of Racial Disparities in Prostate Cancer
    Learning Objectives: 1. Understand the evolving epidemiology of prostate cancer in the the US and globally, and the excess burden of disease borne by men of African ancestry 2. Describe the...
    Speaker: Matthew R. Cooperberg, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 01, 2020 | 10:00 AM
    Improvements to Bile Collection Studies in Rats
    Improvements to Bile Collection Studies in Rats
    Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
    Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
    Sponsored By: SAI Infusion Technologies
    5 3
    SEP 23, 2020 | 10:30 AM
    iPSC- and patient- derived intestinal organoids for gastrointestinal research
    iPSC- and patient- derived intestinal organoids for gastrointestinal...
    Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
    Speaker: Kevin Su
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    SEP 23, 2020 | 12:00 AM
    Extracellular Vesicles and Chronic Kidney Disease
    Extracellular Vesicles and Chronic Kidney Disease
    Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
    Speaker: Sargis Sedrakyan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
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