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    Enhancer

    An Enhancer is a small section of DNA that can be used to bind protein together in order to increase the probability that the transcription of a specific gene will develop. There are hundreds of thousands of Enhancers that can be found in Prokaryotic and Eukaryotic cells within the human genome. Enhancers are cis-regulatory elements, which regulate the transcription of nearby genes and are an essential part of genetic regulatory networks.

    Webinars

    • JUL 01, 2017 | 12:00 AM
      Highly efficient stem cell engineering via Cas9 protein transfection
      Highly efficient stem cell engineering via Cas9 protein transfection
      CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering.  The delivery of Cas9 plasmid DNA or mR...
      Speaker: Xiquan Liang
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      JUN 28, 2017 | 9:00 AM
      WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution RNA maps for the regulation of alternative polyadenylation
      WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution...
      DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
      Speaker: Jernej Ule, PhD , Gregor Rot, PhD
      Sponsored By: Lexogen
      5
      JUN 14, 2017 | 6:00 AM
      WEBINAR: Accelerated Data Workflows for Biomarker Discovery in Metabolomics: Clinical Research Applications in Cystic Fibrosis Research
      WEBINAR: Accelerated Data Workflows for Biomarker Discovery in...
      DATE: June 14, 2017TIME: 6:00am PT, 9:00am ET, 3:00pm CETComprehensive metabolite profiling (i.e., metabolomics) offers a holistic approach for understanding the phenotype of an organis...
      Speaker: Philip Britz-McKibbin
      Sponsored By: Agilent
      4
      MAY 23, 2017 | 10:00 AM
      WEBINAR: Vitamin D Metabolites and Clinical Relevance
      WEBINAR: Vitamin D Metabolites and Clinical Relevance
      DATE: May 23, 2017TIME: 10:00am PT, 1:00pm ETA number of studies have shown that vitamin D deficiency is very common in both the developing and developed world. This has increased the i...
      Speaker: Ravinder Singh, PhD
      7 1
      MAY 17, 2017 | 9:00 AM
      The Clinical Utility of 1,25 Dihydroxyvitamin D
      The Clinical Utility of 1,25 Dihydroxyvitamin D
      DATE: May 17, 2017TIME: 9:00am PT, 12:00pm ETPracticing Internist and vitamin D researcher Gregory A. Plotnikoff, MD, MTS, FACP, will review how new testing for 1,25-Dihydroxy...
      Speaker: Gregory Plotnikoff, MD, MTS, FACP
      Presented at: Discover More; Your Virtual Resource
      Sponsored By: Diasorin
      12 2
      MAY 11, 2017 | 9:00 AM
      Keynote Presentation - Using network models to understand common complex disease predisposition and progression
      Keynote Presentation - Using network models to understand common...
      The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2017
      1
      MAY 10, 2017 | 3:00 PM
      Large scale serum free suspension lentiviral production for cell and gene therapy application
      Large scale serum free suspension lentiviral production for cell...
      Lentiviral vectors have become the center of attention for its use as gene transfer vectors in gene therapy. Here, we have developed a new lentiviral production system for the clinical grade...
      Speaker: Yongchang Ji, PhD.
      Presented at: 2017 Gibco ExpressionWorld
      4 1
      MAY 10, 2017 | 2:00 PM
      Selecting the right resin to achieve optimal results, from high throughput batch to process scale protein purification
      Selecting the right resin to achieve optimal results, from high...
      The objective of academic, biotech or pharmaceutical scientists committed to protein purification is to obtain the purest protein needed for their application, regardless of scale. Towards th...
      Speaker: Aaron McBride , Scott Meier
      Presented at: 2017 Gibco ExpressionWorld
      7
      MAY 03, 2017 | 10:00 AM
      What are the current advances in Flow Cytometry?
      What are the current advances in Flow Cytometry?
      DATE: May 3, 2017TIME: 10:00am PT, 1:00pm ETA number of new instruments have appeared in recent times to accommodate different applications and highlight technology advances. This webin...
      Speaker: J. Paul Robinson, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      12
      APR 11, 2017 | 8:00 AM
      WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
      WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ...
      DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
      Speaker: Joshua Brody, MD , Michelle Poulin, PhD
      Sponsored By: Standard BioTools
      7 1
      MAR 16, 2017 | 6:00 AM
      Working Memory: Neurophysiological Basis, Development, and Plasticity
      Working Memory: Neurophysiological Basis, Development, and Plasticity
      Working memory ability matures late in life, in adolescence or early adulthood, and may be enhanced even in adulthood through cognitive training. The mechanisms through which working memory i...
      Speaker: Christos Constantinidis, PhD
      Presented at: Neuroscience Virtual Event Series 2017
      1
      MAR 15, 2017 | 10:30 AM
      Neuroanatomical substrates underlying attentional processing
      Neuroanatomical substrates underlying attentional processing
      Basal forebrain cholinergic inputs to the cortex are known to contribute to attentional performance. A major focus of my laboratory has been to study the receptors mediating the effects of ac...
      Speaker: Josh Burk, PhD
      Presented at: Neuroscience Virtual Event Series 2017
      1
      MAR 15, 2017 | 7:30 AM
      Exercise Targeting Neuroplasticity in Parkinson's disease
      Exercise Targeting Neuroplasticity in Parkinson's disease
      Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
      Speaker: Giselle Petzinger, MD
      Presented at: Neuroscience Virtual Event Series 2017
      2
      FEB 23, 2017 | 1:30 PM
      Mining Dense, Dynamic Personal Data Clouds to Enhance Health
      Mining Dense, Dynamic Personal Data Clouds to Enhance Health
      Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
      Speaker: Nathan Price, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      FEB 22, 2017 | 1:30 PM
      Integrating genomics platforms and data in Biobanks
      Integrating genomics platforms and data in Biobanks
      Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
      Speaker: Sami Amr, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      2
      FEB 09, 2017 | 1:30 PM
      Professional Development:  Cornerstone of a Strong Animal Care and Use Program
      Professional Development: Cornerstone of a Strong Animal Care...
      DATE: February 9, 2017TIME: 1:30pm PT, 4:30pm ETThe animal research field has gotten more sophisticated with the use of genetically engineered animals, biohazardous agents, and advanced...
      Speaker: Nicole Duffee, DVM, PhD , Ann Turner PhD, FASAE, CAE
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
      FEB 07, 2017 | 6:00 AM
      C.E. CREDITS
      Heparin Monitoring: aPTT versus Anti-Xa assay
      Heparin Monitoring: aPTT versus Anti-Xa assay
      Learn heparin monitoring using aPTT and anti-Xa assays, their limitations, and how accurate testing improves patient management....
      Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      14 1
      FEB 01, 2017 | 8:00 AM
      WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques for the Analysis of a Development‐Phase Therapeutic Glycoprotein
      WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques...
      DATE: February 1, 2017TIME: 8:00AM PT, 11:00AM ETIn this presentation the complementarity of various liquid phase bioseparation methods including capillary electrophoresis and liquid ch...
      Speaker: Laura Salmeron
      Sponsored By: SCIEX
      13 3
      DEC 08, 2016 | 7:30 AM
      Tackling the challenge of FFPE DNA Extraction: An automation-ready solution designed with an NGS focus
      Tackling the challenge of FFPE DNA Extraction: An automation-ready...
      DATE: December 8th, 2016 TIME:  7:30am PT, 10:30am ET Increasingly, Formalin-Fixed, Paraffin-Embedded (FFPE) samples are an essential part of many next-generation sequencing (NGS) sa...
      Speaker: Kathy Munkvold, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      5 2
      NOV 17, 2016 | 3:00 PM
      Molecular elucidation and engineering of stem cell fate decisions
      Molecular elucidation and engineering of stem cell fate decisions
      Stem cells play critical roles in the development of organisms, as well as in the maintenance and repair of organs and tissues throughout adulthood.  Advancing our understanding of mecha...
      Speaker: David Schaffer, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      4
      NOV 04, 2016 | 10:00 AM
      Applying a multi-omics approach to tumor biomarker discovery - case studies
      Applying a multi-omics approach to tumor biomarker discovery -...
      DATE:  November 4, 2016 TIME:  10:00am PT, 1:00pm ET How do you develop clinically relevant biomarkers? Systematic tumor profiling with multi-omics tools and rapid analytical...
      Speaker: Antonia Sepulveda, MD, PhD , Yang Yang, PhD , Tamara Lotan, MD
      Sponsored By: Affymetrix, Affymetrix
      10 1
      NOV 03, 2016 | 1:30 PM
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
      We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
      Speaker: Fabrizio Bonelli, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 03, 2016 | 6:00 AM
      Automation and core-laboratory: experience of a large European academic hospital
      Automation and core-laboratory: experience of a large European...
      Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
      Speaker: Damien Gruson, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      OCT 06, 2016 | 9:00 AM
      Keynote Speaker - PD-1 cancer immunotherapy
      Keynote Speaker - PD-1 cancer immunotherapy
      The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
      Speaker: Gordon Freeman, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
    JUL 01, 2017 | 12:00 AM
    Highly efficient stem cell engineering via Cas9 protein transfection
    Highly efficient stem cell engineering via Cas9 protein transfection
    CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering.  The delivery of Cas9 plasmid DNA or mR...
    Speaker: Xiquan Liang
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
    JUN 28, 2017 | 9:00 AM
    WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution RNA maps for the regulation of alternative polyadenylation
    WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution...
    DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
    Speaker: Jernej Ule, PhD , Gregor Rot, PhD
    Sponsored By: Lexogen
    5
    JUN 14, 2017 | 6:00 AM
    WEBINAR: Accelerated Data Workflows for Biomarker Discovery in Metabolomics: Clinical Research Applications in Cystic Fibrosis Research
    WEBINAR: Accelerated Data Workflows for Biomarker Discovery in...
    DATE: June 14, 2017TIME: 6:00am PT, 9:00am ET, 3:00pm CETComprehensive metabolite profiling (i.e., metabolomics) offers a holistic approach for understanding the phenotype of an organis...
    Speaker: Philip Britz-McKibbin
    Sponsored By: Agilent
    4
    MAY 23, 2017 | 10:00 AM
    WEBINAR: Vitamin D Metabolites and Clinical Relevance
    WEBINAR: Vitamin D Metabolites and Clinical Relevance
    DATE: May 23, 2017TIME: 10:00am PT, 1:00pm ETA number of studies have shown that vitamin D deficiency is very common in both the developing and developed world. This has increased the i...
    Speaker: Ravinder Singh, PhD
    7 1
    MAY 17, 2017 | 9:00 AM
    The Clinical Utility of 1,25 Dihydroxyvitamin D
    The Clinical Utility of 1,25 Dihydroxyvitamin D
    DATE: May 17, 2017TIME: 9:00am PT, 12:00pm ETPracticing Internist and vitamin D researcher Gregory A. Plotnikoff, MD, MTS, FACP, will review how new testing for 1,25-Dihydroxy...
    Speaker: Gregory Plotnikoff, MD, MTS, FACP
    Presented at: Discover More; Your Virtual Resource
    Sponsored By: Diasorin
    12 2
     
     
  • MAY 11, 2017 | 9:00 AM
    Keynote Presentation - Using network models to understand common complex disease predisposition and progression
    Keynote Presentation - Using network models to understand common...
    The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2017
    1
    MAY 10, 2017 | 3:00 PM
    Large scale serum free suspension lentiviral production for cell and gene therapy application
    Large scale serum free suspension lentiviral production for cell...
    Lentiviral vectors have become the center of attention for its use as gene transfer vectors in gene therapy. Here, we have developed a new lentiviral production system for the clinical grade...
    Speaker: Yongchang Ji, PhD.
    Presented at: 2017 Gibco ExpressionWorld
    4 1
    MAY 10, 2017 | 2:00 PM
    Selecting the right resin to achieve optimal results, from high throughput batch to process scale protein purification
    Selecting the right resin to achieve optimal results, from high...
    The objective of academic, biotech or pharmaceutical scientists committed to protein purification is to obtain the purest protein needed for their application, regardless of scale. Towards th...
    Speaker: Aaron McBride , Scott Meier
    Presented at: 2017 Gibco ExpressionWorld
    7
    MAY 03, 2017 | 10:00 AM
    What are the current advances in Flow Cytometry?
    What are the current advances in Flow Cytometry?
    DATE: May 3, 2017TIME: 10:00am PT, 1:00pm ETA number of new instruments have appeared in recent times to accommodate different applications and highlight technology advances. This webin...
    Speaker: J. Paul Robinson, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    12
    APR 11, 2017 | 8:00 AM
    WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
    WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ...
    DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
    Speaker: Joshua Brody, MD , Michelle Poulin, PhD
    Sponsored By: Standard BioTools
    7 1
     
     
  • MAR 16, 2017 | 6:00 AM
    Working Memory: Neurophysiological Basis, Development, and Plasticity
    Working Memory: Neurophysiological Basis, Development, and Plasticity
    Working memory ability matures late in life, in adolescence or early adulthood, and may be enhanced even in adulthood through cognitive training. The mechanisms through which working memory i...
    Speaker: Christos Constantinidis, PhD
    Presented at: Neuroscience Virtual Event Series 2017
    1
    MAR 15, 2017 | 10:30 AM
    Neuroanatomical substrates underlying attentional processing
    Neuroanatomical substrates underlying attentional processing
    Basal forebrain cholinergic inputs to the cortex are known to contribute to attentional performance. A major focus of my laboratory has been to study the receptors mediating the effects of ac...
    Speaker: Josh Burk, PhD
    Presented at: Neuroscience Virtual Event Series 2017
    1
    MAR 15, 2017 | 7:30 AM
    Exercise Targeting Neuroplasticity in Parkinson's disease
    Exercise Targeting Neuroplasticity in Parkinson's disease
    Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
    Speaker: Giselle Petzinger, MD
    Presented at: Neuroscience Virtual Event Series 2017
    2
    FEB 23, 2017 | 1:30 PM
    Mining Dense, Dynamic Personal Data Clouds to Enhance Health
    Mining Dense, Dynamic Personal Data Clouds to Enhance Health
    Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
    Speaker: Nathan Price, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
    FEB 22, 2017 | 1:30 PM
    Integrating genomics platforms and data in Biobanks
    Integrating genomics platforms and data in Biobanks
    Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
    Speaker: Sami Amr, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    2
     
     
  • FEB 09, 2017 | 1:30 PM
    Professional Development:  Cornerstone of a Strong Animal Care and Use Program
    Professional Development: Cornerstone of a Strong Animal Care...
    DATE: February 9, 2017TIME: 1:30pm PT, 4:30pm ETThe animal research field has gotten more sophisticated with the use of genetically engineered animals, biohazardous agents, and advanced...
    Speaker: Nicole Duffee, DVM, PhD , Ann Turner PhD, FASAE, CAE
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
    FEB 07, 2017 | 6:00 AM
    C.E. CREDITS
    Heparin Monitoring: aPTT versus Anti-Xa assay
    Heparin Monitoring: aPTT versus Anti-Xa assay
    Learn heparin monitoring using aPTT and anti-Xa assays, their limitations, and how accurate testing improves patient management....
    Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    14 1
    FEB 01, 2017 | 8:00 AM
    WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques for the Analysis of a Development‐Phase Therapeutic Glycoprotein
    WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques...
    DATE: February 1, 2017TIME: 8:00AM PT, 11:00AM ETIn this presentation the complementarity of various liquid phase bioseparation methods including capillary electrophoresis and liquid ch...
    Speaker: Laura Salmeron
    Sponsored By: SCIEX
    13 3
    DEC 08, 2016 | 7:30 AM
    Tackling the challenge of FFPE DNA Extraction: An automation-ready solution designed with an NGS focus
    Tackling the challenge of FFPE DNA Extraction: An automation-ready...
    DATE: December 8th, 2016 TIME:  7:30am PT, 10:30am ET Increasingly, Formalin-Fixed, Paraffin-Embedded (FFPE) samples are an essential part of many next-generation sequencing (NGS) sa...
    Speaker: Kathy Munkvold, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    5 2
    NOV 17, 2016 | 3:00 PM
    Molecular elucidation and engineering of stem cell fate decisions
    Molecular elucidation and engineering of stem cell fate decisions
    Stem cells play critical roles in the development of organisms, as well as in the maintenance and repair of organs and tissues throughout adulthood.  Advancing our understanding of mecha...
    Speaker: David Schaffer, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    4
     
     
  • NOV 04, 2016 | 10:00 AM
    Applying a multi-omics approach to tumor biomarker discovery - case studies
    Applying a multi-omics approach to tumor biomarker discovery -...
    DATE:  November 4, 2016 TIME:  10:00am PT, 1:00pm ET How do you develop clinically relevant biomarkers? Systematic tumor profiling with multi-omics tools and rapid analytical...
    Speaker: Antonia Sepulveda, MD, PhD , Yang Yang, PhD , Tamara Lotan, MD
    Sponsored By: Affymetrix, Affymetrix
    10 1
    NOV 03, 2016 | 1:30 PM
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
    We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
    Speaker: Fabrizio Bonelli, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 03, 2016 | 6:00 AM
    Automation and core-laboratory: experience of a large European academic hospital
    Automation and core-laboratory: experience of a large European...
    Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
    Speaker: Damien Gruson, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    OCT 06, 2016 | 9:00 AM
    Keynote Speaker - PD-1 cancer immunotherapy
    Keynote Speaker - PD-1 cancer immunotherapy
    The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
    Speaker: Gordon Freeman, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
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