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    Pre-Clinical

    Pre-Clinical: relating to or denoting a stage preceding a clinical stage, in particular.

    Webinars

    • MAY 31, 2018 | 7:30 AM
      Keynote Presentation: NCATS Automation Capabilities - Where We Are and Where We Are Going
      Keynote Presentation: NCATS Automation Capabilities - Where We...
      Over the years high throughput screening has evolved from monolithic static systems to modular more dynamic platforms.  At NCATS the approach taken has been to optimize our existing lega...
      Speaker: Sam Michael
      Presented at: Lab Automation Virtual Event Series 2018
      1
      MAY 30, 2018 | 10:30 AM
      Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
      Inhibitors of NSD2 Discovered by High-Throughput Screening with...
      NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
      Speaker: Nathan Coussens, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      MAY 24, 2018 | 9:30 AM
      Turning to a new dimension in cell culture for cancer research
      Turning to a new dimension in cell culture for cancer research
      DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
      Speaker: Carlemi Calitz, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      14 2
      MAY 02, 2018 | 8:00 AM
      Five steps for publication-quality immunohistochemistry imaging
      Five steps for publication-quality immunohistochemistry imaging
      Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
      Speaker: Jason Kilgore
      Sponsored By: Thermo Fisher Scientific
      10
      APR 26, 2018 | 8:00 AM
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
      DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
      Speaker: Kristin Anderson, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      5
      APR 25, 2018 | 8:00 AM
      C.E. CREDITS
      Quality in the Coagulation Laboratory
      Quality in the Coagulation Laboratory
      Learn to optimize coagulation lab quality through root cause analysis, case studies, and protocols to prevent errors and improve patient care....
      Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      11 2
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      MAR 29, 2018 | 12:00 PM
      A Comprehensive Strategy for Residue Analysis in Cannabis and Industrial Hemp
      A Comprehensive Strategy for Residue Analysis in Cannabis and...
      Pesticide residue screening is a pre-sale requirement for all states which have legalized the recreational or adult use of cannabis and cannabis related products.  In the absence of guid...
      Speaker: Rick Jordan
      Presented at: Cannabis Sciences Virtual Event Series 2018
      Sponsored By: Agilent
      1
      MAR 14, 2018 | 12:00 PM
      Decoding How Clathrin is Transported to Distal Synapses Along Axons
      Decoding How Clathrin is Transported to Distal Synapses Along...
      Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
      Speaker: Archan Ganguly, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
      FEB 22, 2018 | 9:00 AM
      Clinical Implementation of Pharmacogenomics: Delivering Genomics to the Bedside
      Clinical Implementation of Pharmacogenomics: Delivering Genomics...
      Pharmacogenomics has emerged as an early use case of precision medicine.  Delivering this new clinical data to clinicians in a ready to use format can be challenging.  This talk wil...
      Speaker: Mark Dunnenberger, PharmD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      FEB 08, 2018 | 1:30 PM
      Applications of Preclinical Translational Imaging Technologies for Improved Modeling and Decision Making
      Applications of Preclinical Translational Imaging Technologies...
      Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
      Speaker: Paul Makidon, DVM, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      3
      NOV 16, 2017 | 9:00 AM
      WEBINAR: Breaking Bad with 3D: The development of high throughput screening platforms to interrogate physiologically relevant models
      WEBINAR: Breaking Bad with 3D: The development of high throughput...
      DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
      Speaker: Madhu Nag, PhD
      Sponsored By: Revvity
      4
      NOV 09, 2017 | 1:30 PM
      Importance of Measuring the Inhibition of Platelet Thromboxanes by Aspirin in Cardiovascular Disease Management and Prevention
      Importance of Measuring the Inhibition of Platelet Thromboxanes...
      Antiplatelet therapy with aspirin (ASA) is widely used in cardiovascular disease (CVD) prevention because it inhibits platelet cyclooxygenase-1 (COX-1) and thromboxane A2 (TXA2)-mediated plat...
      Speaker: Luis Lopez, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
      NOV 09, 2017 | 1:30 PM
      The Development and Commercialization of Robust Circulating DNA and RNA Tests
      The Development and Commercialization of Robust Circulating DNA...
      The GeneStrat® Genomic Test is a blood-based series of ddPCR tests for DNA (EGFR, KRAS, BRAF) and multiplexed assays for RNA variants (EML4-ALK, ROS1, RET).  In this report we will u...
      Speaker: Hestia Mellert, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
      NOV 09, 2017 | 12:00 PM
      Is Free 25OH Vitamin D The Next Generation Vitamin D Marker?
      Is Free 25OH Vitamin D The Next Generation Vitamin D Marker?
      Free 25OH Vitamin D has received increasing attention over the last four years. More and more studies support the importance of free 25OH Vitamin D, suggesting that this fraction of 25OH Vita...
      Speaker: Nicolas Heureux
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      2
      NOV 09, 2017 | 12:00 PM
      Understanding T Cell Responses in Tuberculosis-Latest research on QuantiFERON-TB Gold Plus
      Understanding T Cell Responses in Tuberculosis-Latest research...
      QuantiFERON TB (QFT) was the first interferon gamma release assay (IGRA) utilizing whole blood stimulation as a test for TB infection, gaining FDA approval in 2001. Subsequently there have be...
      Speaker: Jeff Boyle, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      3
      NOV 09, 2017 | 10:30 AM
      Fast Phenotypic Antibiotic Susceptibility Testing of Positive Blood Cultures
      Fast Phenotypic Antibiotic Susceptibility Testing of Positive...
      The role of the microbiology laboratory in the processing of positive patient blood cultures has become more complicated with the increasing demand for rapid information to assist in the mana...
      Speaker: Margie Morgan, PhD, D(ABMM), MT(ASCP)
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      Sponsored By: Accelerate Diagnostics
      3
      NOV 09, 2017 | 10:30 AM
      The Need for Serum 25-hydroxyvitamin D Standardization in Clinical and Research Laboratories
      The Need for Serum 25-hydroxyvitamin D Standardization in Clinical...
      This webinar builds and expands on the recent labroots webinar by Dr. Gary Horowitz to emphasize how relatively in expensive assay standardization procedures can be incorporated into clinical...
      Speaker: Christopher T. Sempos, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
      NOV 09, 2017 | 9:00 AM
      Monitoring Pain Management Medications in Pregnancy and the Neonate
      Monitoring Pain Management Medications in Pregnancy and the Neonate
      Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines.  Pain does not go away, and may intensify...
      Speaker: Gwen McMillin, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
      NOV 09, 2017 | 9:00 AM
      Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢ Gene Expression Panel, Advanced Data Analysis Service, and Signature Development
      Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢...
      Transcriptional profiling of the tumor microenvironment can lead to insights about the interaction between the tumor and immune system. This facilitates investigation of immune evasion mechan...
      Speaker: Sarah Warren, PhD , Patrick Danaher, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      Sponsored By: NanoString Technologies
      1
      NOV 09, 2017 | 7:30 AM
      Keynote Presentation: Integration of the Simplexa C. difficile Direct assay into a two-step algorithm for the laboratory diagnosis of C. difficile
      Keynote Presentation: Integration of the Simplexa C. difficile...
      Clostridium difficile infection (CDI) has become the leading cause of healthcare associated infections in the United States and currently accounts for 15% to 20% of infectious diarrhea in the...
      Speaker: Dr. James Snyder
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
      NOV 09, 2017 | 6:00 AM
      Biosafety Risk Assessment Fundamentals for Clinical Laboratories
      Biosafety Risk Assessment Fundamentals for Clinical Laboratories
      This session will review and describe the basic steps of a biosafety risk assessment for clinical laboratories.  The risk of exposure to infectious agents exists in every clinical labora...
      Speaker: Michael Pentella, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      9
      NOV 09, 2017 | 6:00 AM
      Blood trails: nanotechnology-enabled biomarker quantification for early disease detection
      Blood trails: nanotechnology-enabled biomarker quantification...
      Dr. Tony Hu’s research focuses on developing and validating integrated nanotechnique-based strategies for marker discovery and molecular diagnostics in peripheral blood samples to provi...
      Speaker: Tony Hu, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
      NOV 08, 2017 | 1:30 PM
      Rapid Variant Interpretation and Reporting Using the QIAGEN Knowledgebase and QIAGEN Clinical Insight - Interpret (QCI-I)
      Rapid Variant Interpretation and Reporting Using the QIAGEN Knowledgebase...
      The advent of next generation sequencing has transformed the way we identify mutations with clinical implications. As the compendium of variants expands, gathering the most current and accura...
      Speaker: Jennifer Poitras, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      1
    MAY 31, 2018 | 7:30 AM
    Keynote Presentation: NCATS Automation Capabilities - Where We Are and Where We Are Going
    Keynote Presentation: NCATS Automation Capabilities - Where We...
    Over the years high throughput screening has evolved from monolithic static systems to modular more dynamic platforms.  At NCATS the approach taken has been to optimize our existing lega...
    Speaker: Sam Michael
    Presented at: Lab Automation Virtual Event Series 2018
    1
    MAY 30, 2018 | 10:30 AM
    Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
    Inhibitors of NSD2 Discovered by High-Throughput Screening with...
    NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
    Speaker: Nathan Coussens, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
    MAY 24, 2018 | 9:30 AM
    Turning to a new dimension in cell culture for cancer research
    Turning to a new dimension in cell culture for cancer research
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    Speaker: Carlemi Calitz, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    14 2
    MAY 02, 2018 | 8:00 AM
    Five steps for publication-quality immunohistochemistry imaging
    Five steps for publication-quality immunohistochemistry imaging
    Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
    Speaker: Jason Kilgore
    Sponsored By: Thermo Fisher Scientific
    10
    APR 26, 2018 | 8:00 AM
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
    DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
    Speaker: Kristin Anderson, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    5
     
     
  • APR 25, 2018 | 8:00 AM
    C.E. CREDITS
    Quality in the Coagulation Laboratory
    Quality in the Coagulation Laboratory
    Learn to optimize coagulation lab quality through root cause analysis, case studies, and protocols to prevent errors and improve patient care....
    Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    11 2
    APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    MAR 29, 2018 | 12:00 PM
    A Comprehensive Strategy for Residue Analysis in Cannabis and Industrial Hemp
    A Comprehensive Strategy for Residue Analysis in Cannabis and...
    Pesticide residue screening is a pre-sale requirement for all states which have legalized the recreational or adult use of cannabis and cannabis related products.  In the absence of guid...
    Speaker: Rick Jordan
    Presented at: Cannabis Sciences Virtual Event Series 2018
    Sponsored By: Agilent
    1
    MAR 14, 2018 | 12:00 PM
    Decoding How Clathrin is Transported to Distal Synapses Along Axons
    Decoding How Clathrin is Transported to Distal Synapses Along...
    Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
    Speaker: Archan Ganguly, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
    FEB 22, 2018 | 9:00 AM
    Clinical Implementation of Pharmacogenomics: Delivering Genomics to the Bedside
    Clinical Implementation of Pharmacogenomics: Delivering Genomics...
    Pharmacogenomics has emerged as an early use case of precision medicine.  Delivering this new clinical data to clinicians in a ready to use format can be challenging.  This talk wil...
    Speaker: Mark Dunnenberger, PharmD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
     
     
  • FEB 08, 2018 | 1:30 PM
    Applications of Preclinical Translational Imaging Technologies for Improved Modeling and Decision Making
    Applications of Preclinical Translational Imaging Technologies...
    Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
    Speaker: Paul Makidon, DVM, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
    3
    NOV 16, 2017 | 9:00 AM
    WEBINAR: Breaking Bad with 3D: The development of high throughput screening platforms to interrogate physiologically relevant models
    WEBINAR: Breaking Bad with 3D: The development of high throughput...
    DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
    Speaker: Madhu Nag, PhD
    Sponsored By: Revvity
    4
    NOV 09, 2017 | 1:30 PM
    Importance of Measuring the Inhibition of Platelet Thromboxanes by Aspirin in Cardiovascular Disease Management and Prevention
    Importance of Measuring the Inhibition of Platelet Thromboxanes...
    Antiplatelet therapy with aspirin (ASA) is widely used in cardiovascular disease (CVD) prevention because it inhibits platelet cyclooxygenase-1 (COX-1) and thromboxane A2 (TXA2)-mediated plat...
    Speaker: Luis Lopez, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
    NOV 09, 2017 | 1:30 PM
    The Development and Commercialization of Robust Circulating DNA and RNA Tests
    The Development and Commercialization of Robust Circulating DNA...
    The GeneStrat® Genomic Test is a blood-based series of ddPCR tests for DNA (EGFR, KRAS, BRAF) and multiplexed assays for RNA variants (EML4-ALK, ROS1, RET).  In this report we will u...
    Speaker: Hestia Mellert, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
    NOV 09, 2017 | 12:00 PM
    Is Free 25OH Vitamin D The Next Generation Vitamin D Marker?
    Is Free 25OH Vitamin D The Next Generation Vitamin D Marker?
    Free 25OH Vitamin D has received increasing attention over the last four years. More and more studies support the importance of free 25OH Vitamin D, suggesting that this fraction of 25OH Vita...
    Speaker: Nicolas Heureux
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    2
     
     
  • NOV 09, 2017 | 12:00 PM
    Understanding T Cell Responses in Tuberculosis-Latest research on QuantiFERON-TB Gold Plus
    Understanding T Cell Responses in Tuberculosis-Latest research...
    QuantiFERON TB (QFT) was the first interferon gamma release assay (IGRA) utilizing whole blood stimulation as a test for TB infection, gaining FDA approval in 2001. Subsequently there have be...
    Speaker: Jeff Boyle, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    3
    NOV 09, 2017 | 10:30 AM
    Fast Phenotypic Antibiotic Susceptibility Testing of Positive Blood Cultures
    Fast Phenotypic Antibiotic Susceptibility Testing of Positive...
    The role of the microbiology laboratory in the processing of positive patient blood cultures has become more complicated with the increasing demand for rapid information to assist in the mana...
    Speaker: Margie Morgan, PhD, D(ABMM), MT(ASCP)
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    Sponsored By: Accelerate Diagnostics
    3
    NOV 09, 2017 | 10:30 AM
    The Need for Serum 25-hydroxyvitamin D Standardization in Clinical and Research Laboratories
    The Need for Serum 25-hydroxyvitamin D Standardization in Clinical...
    This webinar builds and expands on the recent labroots webinar by Dr. Gary Horowitz to emphasize how relatively in expensive assay standardization procedures can be incorporated into clinical...
    Speaker: Christopher T. Sempos, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
    NOV 09, 2017 | 9:00 AM
    Monitoring Pain Management Medications in Pregnancy and the Neonate
    Monitoring Pain Management Medications in Pregnancy and the Neonate
    Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines.  Pain does not go away, and may intensify...
    Speaker: Gwen McMillin, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
    NOV 09, 2017 | 9:00 AM
    Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢ Gene Expression Panel, Advanced Data Analysis Service, and Signature Development
    Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢...
    Transcriptional profiling of the tumor microenvironment can lead to insights about the interaction between the tumor and immune system. This facilitates investigation of immune evasion mechan...
    Speaker: Sarah Warren, PhD , Patrick Danaher, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    Sponsored By: NanoString Technologies
    1
     
     
  • NOV 09, 2017 | 7:30 AM
    Keynote Presentation: Integration of the Simplexa C. difficile Direct assay into a two-step algorithm for the laboratory diagnosis of C. difficile
    Keynote Presentation: Integration of the Simplexa C. difficile...
    Clostridium difficile infection (CDI) has become the leading cause of healthcare associated infections in the United States and currently accounts for 15% to 20% of infectious diarrhea in the...
    Speaker: Dr. James Snyder
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
    NOV 09, 2017 | 6:00 AM
    Biosafety Risk Assessment Fundamentals for Clinical Laboratories
    Biosafety Risk Assessment Fundamentals for Clinical Laboratories
    This session will review and describe the basic steps of a biosafety risk assessment for clinical laboratories.  The risk of exposure to infectious agents exists in every clinical labora...
    Speaker: Michael Pentella, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    9
    NOV 09, 2017 | 6:00 AM
    Blood trails: nanotechnology-enabled biomarker quantification for early disease detection
    Blood trails: nanotechnology-enabled biomarker quantification...
    Dr. Tony Hu’s research focuses on developing and validating integrated nanotechnique-based strategies for marker discovery and molecular diagnostics in peripheral blood samples to provi...
    Speaker: Tony Hu, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
    NOV 08, 2017 | 1:30 PM
    Rapid Variant Interpretation and Reporting Using the QIAGEN Knowledgebase and QIAGEN Clinical Insight - Interpret (QCI-I)
    Rapid Variant Interpretation and Reporting Using the QIAGEN Knowledgebase...
    The advent of next generation sequencing has transformed the way we identify mutations with clinical implications. As the compendium of variants expands, gathering the most current and accura...
    Speaker: Jennifer Poitras, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    1
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