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    Targeted Therapy

    Targeted Therapy: one of the major modalities of medical treatment for cancer, others being hormonal therapy and cytotoxic chemotherapy.

    Webinars

    • NOV 07, 2017 | 10:00 AM
      WEBINAR: Chimeric Antigen Receptors: From proof of concept to widely applicable clinical research solutions
      WEBINAR: Chimeric Antigen Receptors: From proof of concept to...
      DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
      Speaker: Dina Schneider, B.Sc.Pharm, PhD
      Sponsored By: Miltenyi Biotec
      9 2
      OCT 17, 2017 | 8:00 AM
      WEBINAR: Transcriptomics to decipher the pathobiology of drug resistance and enable targeted therapeutics
      WEBINAR: Transcriptomics to decipher the pathobiology of drug...
      DATE: October 17, 2017TIME: 08:00am PDT, 11:00am EDTResearching and understanding the mechanisms of drug resistance are essential to determine therapies that are more effective on an in...
      Speaker: Yesim Gökmen-Polar, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      8 1
      OCT 12, 2017 | 10:30 AM
      Hypersecretion of fibroblast-derived exosomes during chemotherapy promotes pancreatic cancer chemoresistance
      Hypersecretion of fibroblast-derived exosomes during chemotherapy...
      Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
      Speaker: Reginald Hill, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      OCT 12, 2017 | 6:00 AM
      Inference of gene signatures associated with response and resistance to targeted and immunotherapies
      Inference of gene signatures associated with response and resistance...
      We developed two computational methods, CARE and TIDE, to predict response and resistance to targeted therapies and immunotherapies. CARE infers gene signatures of targeted therapy response b...
      Speaker: Xiaole Shirley Liu, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      OCT 11, 2017 | 1:30 PM
      Pancreatic Cancer:  Challenges and Solutions
      Pancreatic Cancer: Challenges and Solutions
      Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%.  Although ranking 12th in terms of incidence, it is...
      Speaker: Lynn Matrisian, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      OCT 11, 2017 | 6:00 AM
      Cancer Chemotherapy and the tools needed to Advance Treatment in a Diverse Racial Population
      Cancer Chemotherapy and the tools needed to Advance Treatment...
      Colorectal  cancer  (CRC)  is  the  third  most  commonly  diagnosed  cancer  and  is  the  third leading  cause of  ...
      Speaker: Jennie Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      OCT 10, 2017 | 9:00 AM
      WEBINAR: Automated single cell dissociation of primary tumors and patient-derived xenografts
      WEBINAR: Automated single cell dissociation of primary tumors...
      DATE: October 10, 2017TIME: 9:00AM PDTPatient-derived xenografts (PDX) are increasingly being used in biomedical research for therapeutic analysis in mice. Unlike traditional cell line...
      Speaker: J.T. Poirier, PhD
      Sponsored By: Miltenyi Biotec
      4
      SEP 28, 2017 | 10:00 AM
      WEBINAR: Development of anti-cancer gene therapies through understanding of cytokine-induced programmed cell death
      WEBINAR: Development of anti-cancer gene therapies through understanding...
      DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
      Speaker: Leah Persaud
      Sponsored By: Thermo Fisher Scientific/Gibco
      11 2
      SEP 13, 2017 | 1:30 PM
      The escalating challenges of antimicrobial resistance and the efforts to conquer these threats
      The escalating challenges of antimicrobial resistance and the...
      The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
      Speaker: Glenn Tillotson, PhD, FIDSA, FCCP
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      3 1
      SEP 13, 2017 | 7:30 AM
      Keynote Presentation: Using phage to select for evolution of reduced virulence in pathogenic bacteria
      Keynote Presentation: Using phage to select for evolution of reduced...
      Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies.  Ideally, new approaches would target bacterial pat...
      Speaker: Paul Turner, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      1
      SEP 13, 2017 | 6:00 AM
      Next-generation probiotics targeting C. difficile infection
      Next-generation probiotics targeting C. difficile infection
      Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
      Speaker: Jennifer Spinler, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      1
      SEP 07, 2017 | 9:00 AM
      WEBINAR: Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
      WEBINAR: Glycosylation and stabilization of programmed death ligand-1...
      DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
      Speaker: Chia-Wei Li, PhD
      Sponsored By: Essen BioScience
      5
      AUG 30, 2017 | 10:00 AM
      WEBINAR: Understanding cell reprogramming in treatment-resistant prostate cancer using organoids
      WEBINAR: Understanding cell reprogramming in treatment-resistant...
      DATE: August 30, 2017TIME: 10:00am PT, 1:00pm ETRecent studies show that cancer cells can resist treatment by changing into a different cell type. Many treatments for specific cancers,...
      Speaker: Kristine Wadosky, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 2
      AUG 01, 2017 | 12:00 AM
      Accelerating cures for rare childhood diseases using iPSC models
      Accelerating cures for rare childhood diseases using iPSC models
      Creating inducible Pluripotent Stem Cell (iPSC) collections of rare patients scattered world-wide can lower the barrier of biological discovery of rare disease, provide a platform for potenti...
      Speaker: Christina Waters
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      JUL 25, 2017 | 9:00 AM
      WEBINAR: Functional Genomics and Drug Metabolism
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      7 1
      JUL 20, 2017 | 8:00 AM
      WEBINAR: Application of targeted next-generation sequencing (NGS) panels in neurodevelopmental disorder research
      WEBINAR: Application of targeted next-generation sequencing (NGS)...
      DATE: July 20, 2017TIME: 8:00am PT, 11:00am ET, 5:00pm CESTNeurodevelopmental disorders (NDDs) are clinically and etiologically highly heterogeneous and are characterized by a...
      Speaker: Alessandra Murgia , Francisco Hernandez-Guzman
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      5
      JUL 01, 2017 | 8:00 AM
      Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1 and SDC2, as markers for isolation of human ES/iPS cell-derived muscle progenitors
      Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1...
      Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
      Speaker: Alessandro Magli
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      JUL 01, 2017 | 8:00 AM
      Industry uses of human pluripotent stem cells
      Industry uses of human pluripotent stem cells
      Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
      Speaker: Stuart Chambers
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUN 08, 2017 | 12:00 PM
      Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing the Latest Technologies from Thermo Fisher Scientific
      Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing...
      The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
      Speaker: Rhonda Newman, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUN 08, 2017 | 10:00 AM
      WEBINAR: Analysis of the transcriptome of carriers of pathological variants in PSEN1, PSEN2 and APP that cause Alzheimer's Disease
      WEBINAR: Analysis of the transcriptome of carriers of pathological...
      DATE: June 8, 2017TIME: 10:00AM PDT, 1:00PM EDT, 7:00PM CESTAlzheimer’s Disease (AD) is the result of complex interactions between risk factors that cause pleiotropic changes in m...
      Speaker: Oscar Harari, PhD
      Sponsored By: Lexogen
      6
      MAY 25, 2017 | 10:30 AM
      Open Targets Platform: mining gene and disease evidence for improved drug target selection.
      Open Targets Platform: mining gene and disease evidence for improved...
      Open Targets is a public-private partnership made up of four global leading institutions in the fields of pharmaceuticals, bioinformatics and genomics, GSK, EMBL-EBI, the Wellcome Trust Sange...
      Speaker: Denise Carvalho-Silva
      Presented at: Lab Automation Virtual Event Series 2017
      1
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
      MAY 10, 2017 | 10:30 AM
      C.E. CREDITS
      Delivering on the promise of Personalized Molecular Medicine
      Delivering on the promise of Personalized Molecular Medicine
      The realization of the promise of personalized molecular medicine requires efficient development and implementation of novel targeted therapeutics linked to molecular markers able to identify...
      Speaker: Gordon B Mills, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      2
      MAY 09, 2017 | 10:00 AM
      WEBINAR: Querying Cytokine-Signaling Networks in Myeloproliferative Neoplasms
      WEBINAR: Querying Cytokine-Signaling Networks in Myeloproliferative...
      DATE: May 9th, 2017TIME: 10:00AM PDT, 1:00PM ETMyeloproliferative neoplasms including myelofibrosis (MF) are characterized by anemia, splenomegaly, bone marrow fibrosis and inflammatory...
      Speaker: Stephen Oh, MD, PhD , Jennifer Frahm, PhD
      Sponsored By: Standard BioTools
      7
    NOV 07, 2017 | 10:00 AM
    WEBINAR: Chimeric Antigen Receptors: From proof of concept to widely applicable clinical research solutions
    WEBINAR: Chimeric Antigen Receptors: From proof of concept to...
    DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
    Speaker: Dina Schneider, B.Sc.Pharm, PhD
    Sponsored By: Miltenyi Biotec
    9 2
    OCT 17, 2017 | 8:00 AM
    WEBINAR: Transcriptomics to decipher the pathobiology of drug resistance and enable targeted therapeutics
    WEBINAR: Transcriptomics to decipher the pathobiology of drug...
    DATE: October 17, 2017TIME: 08:00am PDT, 11:00am EDTResearching and understanding the mechanisms of drug resistance are essential to determine therapies that are more effective on an in...
    Speaker: Yesim Gökmen-Polar, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    8 1
    OCT 12, 2017 | 10:30 AM
    Hypersecretion of fibroblast-derived exosomes during chemotherapy promotes pancreatic cancer chemoresistance
    Hypersecretion of fibroblast-derived exosomes during chemotherapy...
    Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
    Speaker: Reginald Hill, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    OCT 12, 2017 | 6:00 AM
    Inference of gene signatures associated with response and resistance to targeted and immunotherapies
    Inference of gene signatures associated with response and resistance...
    We developed two computational methods, CARE and TIDE, to predict response and resistance to targeted therapies and immunotherapies. CARE infers gene signatures of targeted therapy response b...
    Speaker: Xiaole Shirley Liu, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    OCT 11, 2017 | 1:30 PM
    Pancreatic Cancer:  Challenges and Solutions
    Pancreatic Cancer: Challenges and Solutions
    Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%.  Although ranking 12th in terms of incidence, it is...
    Speaker: Lynn Matrisian, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
     
     
  • OCT 11, 2017 | 6:00 AM
    Cancer Chemotherapy and the tools needed to Advance Treatment in a Diverse Racial Population
    Cancer Chemotherapy and the tools needed to Advance Treatment...
    Colorectal  cancer  (CRC)  is  the  third  most  commonly  diagnosed  cancer  and  is  the  third leading  cause of  ...
    Speaker: Jennie Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    OCT 10, 2017 | 9:00 AM
    WEBINAR: Automated single cell dissociation of primary tumors and patient-derived xenografts
    WEBINAR: Automated single cell dissociation of primary tumors...
    DATE: October 10, 2017TIME: 9:00AM PDTPatient-derived xenografts (PDX) are increasingly being used in biomedical research for therapeutic analysis in mice. Unlike traditional cell line...
    Speaker: J.T. Poirier, PhD
    Sponsored By: Miltenyi Biotec
    4
    SEP 28, 2017 | 10:00 AM
    WEBINAR: Development of anti-cancer gene therapies through understanding of cytokine-induced programmed cell death
    WEBINAR: Development of anti-cancer gene therapies through understanding...
    DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
    Speaker: Leah Persaud
    Sponsored By: Thermo Fisher Scientific/Gibco
    11 2
    SEP 13, 2017 | 1:30 PM
    The escalating challenges of antimicrobial resistance and the efforts to conquer these threats
    The escalating challenges of antimicrobial resistance and the...
    The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
    Speaker: Glenn Tillotson, PhD, FIDSA, FCCP
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    3 1
    SEP 13, 2017 | 7:30 AM
    Keynote Presentation: Using phage to select for evolution of reduced virulence in pathogenic bacteria
    Keynote Presentation: Using phage to select for evolution of reduced...
    Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies.  Ideally, new approaches would target bacterial pat...
    Speaker: Paul Turner, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    1
     
     
  • SEP 13, 2017 | 6:00 AM
    Next-generation probiotics targeting C. difficile infection
    Next-generation probiotics targeting C. difficile infection
    Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
    Speaker: Jennifer Spinler, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    1
    SEP 07, 2017 | 9:00 AM
    WEBINAR: Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
    WEBINAR: Glycosylation and stabilization of programmed death ligand-1...
    DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
    Speaker: Chia-Wei Li, PhD
    Sponsored By: Essen BioScience
    5
    AUG 30, 2017 | 10:00 AM
    WEBINAR: Understanding cell reprogramming in treatment-resistant prostate cancer using organoids
    WEBINAR: Understanding cell reprogramming in treatment-resistant...
    DATE: August 30, 2017TIME: 10:00am PT, 1:00pm ETRecent studies show that cancer cells can resist treatment by changing into a different cell type. Many treatments for specific cancers,...
    Speaker: Kristine Wadosky, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 2
    AUG 01, 2017 | 12:00 AM
    Accelerating cures for rare childhood diseases using iPSC models
    Accelerating cures for rare childhood diseases using iPSC models
    Creating inducible Pluripotent Stem Cell (iPSC) collections of rare patients scattered world-wide can lower the barrier of biological discovery of rare disease, provide a platform for potenti...
    Speaker: Christina Waters
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    JUL 25, 2017 | 9:00 AM
    WEBINAR: Functional Genomics and Drug Metabolism
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
    7 1
     
     
  • JUL 20, 2017 | 8:00 AM
    WEBINAR: Application of targeted next-generation sequencing (NGS) panels in neurodevelopmental disorder research
    WEBINAR: Application of targeted next-generation sequencing (NGS)...
    DATE: July 20, 2017TIME: 8:00am PT, 11:00am ET, 5:00pm CESTNeurodevelopmental disorders (NDDs) are clinically and etiologically highly heterogeneous and are characterized by a...
    Speaker: Alessandra Murgia , Francisco Hernandez-Guzman
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    5
    JUL 01, 2017 | 8:00 AM
    Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1 and SDC2, as markers for isolation of human ES/iPS cell-derived muscle progenitors
    Genomic profiling reveals novel PAX7 targets CD54, integrin α9β1...
    Therapeutic application of pluripotent stem (PS) cell-derived products represents the ultimate goal of stem cell research. In order to apply this technology to patients, it is fundamental to ...
    Speaker: Alessandro Magli
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    JUL 01, 2017 | 8:00 AM
    Industry uses of human pluripotent stem cells
    Industry uses of human pluripotent stem cells
    Human pluripotent stem cells (hPSCs) and their derivatives are increasingly being used in industry to gain a competitive edge in drug discovery and a new wave of biotechnology start-up compan...
    Speaker: Stuart Chambers
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUN 08, 2017 | 12:00 PM
    Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing the Latest Technologies from Thermo Fisher Scientific
    Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing...
    The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
    Speaker: Rhonda Newman, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    JUN 08, 2017 | 10:00 AM
    WEBINAR: Analysis of the transcriptome of carriers of pathological variants in PSEN1, PSEN2 and APP that cause Alzheimer's Disease
    WEBINAR: Analysis of the transcriptome of carriers of pathological...
    DATE: June 8, 2017TIME: 10:00AM PDT, 1:00PM EDT, 7:00PM CESTAlzheimer’s Disease (AD) is the result of complex interactions between risk factors that cause pleiotropic changes in m...
    Speaker: Oscar Harari, PhD
    Sponsored By: Lexogen
    6
     
     
  • MAY 25, 2017 | 10:30 AM
    Open Targets Platform: mining gene and disease evidence for improved drug target selection.
    Open Targets Platform: mining gene and disease evidence for improved...
    Open Targets is a public-private partnership made up of four global leading institutions in the fields of pharmaceuticals, bioinformatics and genomics, GSK, EMBL-EBI, the Wellcome Trust Sange...
    Speaker: Denise Carvalho-Silva
    Presented at: Lab Automation Virtual Event Series 2017
    1
    MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
    MAY 10, 2017 | 10:30 AM
    C.E. CREDITS
    Delivering on the promise of Personalized Molecular Medicine
    Delivering on the promise of Personalized Molecular Medicine
    The realization of the promise of personalized molecular medicine requires efficient development and implementation of novel targeted therapeutics linked to molecular markers able to identify...
    Speaker: Gordon B Mills, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    2
    MAY 09, 2017 | 10:00 AM
    WEBINAR: Querying Cytokine-Signaling Networks in Myeloproliferative Neoplasms
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    DATE: May 9th, 2017TIME: 10:00AM PDT, 1:00PM ETMyeloproliferative neoplasms including myelofibrosis (MF) are characterized by anemia, splenomegaly, bone marrow fibrosis and inflammatory...
    Speaker: Stephen Oh, MD, PhD , Jennifer Frahm, PhD
    Sponsored By: Standard BioTools
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