The brain: is the organ located in the head and serves as the center of the nervous system in all vertebrate. The brain is the most complex organ in a vertebrate's body  and is close to the sensory organs for senses such as vision. 
            
            
            
         
     
    
        
                    
                                    
                
         
                
                    
                                        
                        
                    
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        Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios.  In t...
    
    
            
     
                                     
 
                                    
                                                                    
                                    
                                        
    
    
    
        Approximately 30% of drugs have failed in human clinical trials due to adverse reactions despite promising pre-clinical studies, and another 60% fail due to lack of efficacy. The NIH Tissue C...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        Date:  February 7, 2019Time:  8:00am PST, 11:00am EST Modern microscopes are becoming increasingly complex instruments enabling registration of image sets far beyon...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thou...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        In the postgenomic era, one expects the suite of chemical players in a brain region to be known and their functions uncovered. Perhaps surprisingly, many neurochemicals remain poorly characte...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...