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    Gene Synthesis

    Gene Synthesis: sometimes known as DNA printing[1] is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs.

    Webinars

    • SEP 28, 2017 | 10:00 AM
      WEBINAR: Development of anti-cancer gene therapies through understanding of cytokine-induced programmed cell death
      WEBINAR: Development of anti-cancer gene therapies through understanding...
      DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
      Speaker: Leah Persaud
      Sponsored By: Thermo Fisher Scientific/Gibco
      11 2
      SEP 14, 2017 | 9:00 AM
      Development of tools enabling tunable, in situ delivery of therapeutics using probiotics
      Development of tools enabling tunable, in situ delivery of therapeutics...
      The human large intestine houses trillions of microorganisms which collectively form the highly diverse microbial community known as the gut microbiota. The gut microbiota performs many funct...
      Speaker: Nathan Crook, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      2
      SEP 06, 2017 | 9:00 AM
      WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
      WEBINAR: Manufacturing and characterization of therapeutic exosomes...
      DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
      Speaker: Travis Antes, PhD
      Sponsored By: Miltenyi Biotec
      9
      JUL 25, 2017 | 9:00 AM
      WEBINAR: Functional Genomics and Drug Metabolism
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      7 1
      JUL 01, 2017 | 12:00 AM
      Highly efficient stem cell engineering via Cas9 protein transfection
      Highly efficient stem cell engineering via Cas9 protein transfection
      CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering.  The delivery of Cas9 plasmid DNA or mR...
      Speaker: Xiquan Liang
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUN 28, 2017 | 7:00 AM
      Analytical methods to measure empty and full AAV particles
      Analytical methods to measure empty and full AAV particles
      DATE: June 28, 2017TIME: 7:00am PT, 10am ETAs gene therapy approaches usually require large amounts of AAV vectors for clinical use, few manufacturing processes have been repo...
      Speaker: Christine LeBec, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences
      9 2
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
      MAY 10, 2017 | 5:00 AM
      Complete workflow solution from gene-to-protein combine highly advanced expression systems with expression optimized genes
      Complete workflow solution from gene-to-protein combine highly...
      Reliable autologous expression of recombinant human proteins - from gene sequence to the expressed and purified protein - in human or CHO cells is essential for many aspects of biomedical res...
      Speaker: Stephan Fath, PhD
      Presented at: 2017 Gibco ExpressionWorld
      4 1
      APR 05, 2017 | 7:15 AM
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      CRISPR-Cas9 has increased the accessibility of genome engineering due to its ease of use and ability to cause double strand breaks (DSBs) at almost any locus of interest. DSBs are repaired in...
      Speaker: John Schiel, Ph.D.
      Presented at: Protein Research Live
      5
      FEB 09, 2017 | 6:00 AM
      Acclimation of Training Animals for Standard Handling, Restraint and Laboratory Techniques
      Acclimation of Training Animals for Standard Handling, Restraint...
      DATE:  February 9, 2017TIME: 6:00am PT, 9:00am ETThe University of Michigan’s Unit for Laboratory Animal Medicine (ULAM) has a diverse Training Core that teaches a wide varie...
      Speaker: Kaile Bennett, B.S., R.L.A.T.G.
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      6 4
      DEC 13, 2016 | 8:00 AM
      Improved understanding of rainbow trout growth physiology through functional genomics
      Improved understanding of rainbow trout growth physiology through...
      DATE: December 13, 2016TIME: 8:00 AM PT, 11:00 AM ETUnderstanding physiological mechanisms regulating growth and nutrient deposition in rainbow trout is central to establish production...
      Speaker: Beth Cleveland PhD
      Sponsored By: SCIEX, SCIEX
      32
      NOV 03, 2016 | 10:30 AM
      Rapid, Low-cost Tools for Global Health:  Using Cell-free Synthetic Biology for Zika Virus Detection and the Portable Manufacture of Therapeutics
      Rapid, Low-cost Tools for Global Health: Using Cell-free Synthetic...
      The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions.  In early 2016 we developed a pipe...
      Speaker: Keith Pardee, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      OCT 05, 2016 | 12:00 PM
      Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing the Abundance  of Extremely Rare Mutations Associated with Cancer Diagnosis, Prognosis, and Therapy
      Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing...
      Real-time multiplex PCR assays are potentially the most rapid, most sensitive,and least expensive way to assess the abundance of mutant DNA fragments present in liquid biopsies; provided th...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      MAY 04, 2016 | 1:00 PM
      Mammalian in vitro translation (cell-free) systems for rapid protein expression and production of therapeutic proteins
      Mammalian in vitro translation (cell-free) systems for rapid protein...
      In vitro translation (IVT) using mammalian cell extracts is a quick and convenient alternative to in vivo mammalian protein expression. Thermo Fisher has developed IVT systems from two mammal...
      Speaker: Penny Jensen, PhD , Govind Rao, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAY 04, 2016 | 5:00 AM
      Complete workflow solution from gene-to-protein
      Complete workflow solution from gene-to-protein
      Reliability from gene sequence to the expressed and purified protein is essential for many aspects of basic research and drug development. Thermo Fisher Scientific’s complete portfolio ...
      Speaker: Michael Spring
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAR 31, 2016 | 8:00 AM
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      DATE:  March 31, 2016 TIME:   8am PT, 11am ET, 4pm GMT In this webinar, you will learn:  Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
      Speaker: John Schiel, Ph.D.
      Sponsored By: Dharmacon, Dharmacon
      31 12
      FEB 03, 2016 | 3:00 PM
      Critical Appraisal of Animal Studies
      Critical Appraisal of Animal Studies
      Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
      Speaker: Annette O'Connor, BVSc, MVSc, DVSc, FACVSc
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 6:00 AM
      From the 3Rs to Systematic Reviews
      From the 3Rs to Systematic Reviews
      Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
      Speaker: Merel Ritskes-Hoitinga, DVM, PhD, Animal Welfare Officer, Dipl ECLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      4
      JAN 21, 2016 | 8:00 AM
      How to identify key genes with CRISPR-Cas9 and shRNA screens
      How to identify key genes with CRISPR-Cas9 and shRNA screens
      DATE:  January 21, 2016 TIME:   8am Pacific time, 11am Eastern time In this webinar, you will learn:  basics of pooled lentiviral screening workflows implications of ...
      Speaker: Anja Smith, PhD
      Sponsored By: Dharmacon, Dharmacon
      18 1
      AUG 20, 2014 | 2:15 PM
      Identifying transcriptional regulators of human embryonic development via expression variability
      Identifying transcriptional regulators of human embryonic development...
      Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      FEB 06, 2014 | 11:00 AM
      Formation of Bacterial Biofilms
      Formation of Bacterial Biofilms
      Biofilms, are defined as communities of microorganisms that grow embedded in a self-generated matrix of exopolysaccharides and adhered to an inert surface or a live tissue. They are formed 95...
      Speaker: Yvonne M Heuze de lcaza, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
      Resistance to AR Signaling Inhibitors in Castration Resistant...
      While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
      Speaker: Elahe A Mostaghel, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      AUG 21, 2013 | 10:00 AM
      C.E. CREDITS
      Azole resistance in Aspergillus fumigatus - clinical isolate screening, culture selection, and genetics
      Azole resistance in Aspergillus fumigatus - clinical isolate screening,...
      In the United States, invasive aspergillosis (IA), an invasive fungal infection of the upper respiratory tract of immune compromised patients, is usually caused by Aspergilus fumigatus, while...
      Speaker: William C Nierman, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      67
    SEP 28, 2017 | 10:00 AM
    WEBINAR: Development of anti-cancer gene therapies through understanding of cytokine-induced programmed cell death
    WEBINAR: Development of anti-cancer gene therapies through understanding...
    DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
    Speaker: Leah Persaud
    Sponsored By: Thermo Fisher Scientific/Gibco
    11 2
    SEP 14, 2017 | 9:00 AM
    Development of tools enabling tunable, in situ delivery of therapeutics using probiotics
    Development of tools enabling tunable, in situ delivery of therapeutics...
    The human large intestine houses trillions of microorganisms which collectively form the highly diverse microbial community known as the gut microbiota. The gut microbiota performs many funct...
    Speaker: Nathan Crook, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    2
    SEP 06, 2017 | 9:00 AM
    WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
    WEBINAR: Manufacturing and characterization of therapeutic exosomes...
    DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
    Speaker: Travis Antes, PhD
    Sponsored By: Miltenyi Biotec
    9
    JUL 25, 2017 | 9:00 AM
    WEBINAR: Functional Genomics and Drug Metabolism
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
    7 1
    JUL 01, 2017 | 12:00 AM
    Highly efficient stem cell engineering via Cas9 protein transfection
    Highly efficient stem cell engineering via Cas9 protein transfection
    CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering.  The delivery of Cas9 plasmid DNA or mR...
    Speaker: Xiquan Liang
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
     
     
  • JUN 28, 2017 | 7:00 AM
    Analytical methods to measure empty and full AAV particles
    Analytical methods to measure empty and full AAV particles
    DATE: June 28, 2017TIME: 7:00am PT, 10am ETAs gene therapy approaches usually require large amounts of AAV vectors for clinical use, few manufacturing processes have been repo...
    Speaker: Christine LeBec, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences
    9 2
    MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
    MAY 10, 2017 | 5:00 AM
    Complete workflow solution from gene-to-protein combine highly advanced expression systems with expression optimized genes
    Complete workflow solution from gene-to-protein combine highly...
    Reliable autologous expression of recombinant human proteins - from gene sequence to the expressed and purified protein - in human or CHO cells is essential for many aspects of biomedical res...
    Speaker: Stephan Fath, PhD
    Presented at: 2017 Gibco ExpressionWorld
    4 1
    APR 05, 2017 | 7:15 AM
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    CRISPR-Cas9 has increased the accessibility of genome engineering due to its ease of use and ability to cause double strand breaks (DSBs) at almost any locus of interest. DSBs are repaired in...
    Speaker: John Schiel, Ph.D.
    Presented at: Protein Research Live
    5
    FEB 09, 2017 | 6:00 AM
    Acclimation of Training Animals for Standard Handling, Restraint and Laboratory Techniques
    Acclimation of Training Animals for Standard Handling, Restraint...
    DATE:  February 9, 2017TIME: 6:00am PT, 9:00am ETThe University of Michigan’s Unit for Laboratory Animal Medicine (ULAM) has a diverse Training Core that teaches a wide varie...
    Speaker: Kaile Bennett, B.S., R.L.A.T.G.
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    6 4
     
     
  • DEC 13, 2016 | 8:00 AM
    Improved understanding of rainbow trout growth physiology through functional genomics
    Improved understanding of rainbow trout growth physiology through...
    DATE: December 13, 2016TIME: 8:00 AM PT, 11:00 AM ETUnderstanding physiological mechanisms regulating growth and nutrient deposition in rainbow trout is central to establish production...
    Speaker: Beth Cleveland PhD
    Sponsored By: SCIEX, SCIEX
    32
    NOV 03, 2016 | 10:30 AM
    Rapid, Low-cost Tools for Global Health:  Using Cell-free Synthetic Biology for Zika Virus Detection and the Portable Manufacture of Therapeutics
    Rapid, Low-cost Tools for Global Health: Using Cell-free Synthetic...
    The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions.  In early 2016 we developed a pipe...
    Speaker: Keith Pardee, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    OCT 05, 2016 | 12:00 PM
    Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing the Abundance  of Extremely Rare Mutations Associated with Cancer Diagnosis, Prognosis, and Therapy
    Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing...
    Real-time multiplex PCR assays are potentially the most rapid, most sensitive,and least expensive way to assess the abundance of mutant DNA fragments present in liquid biopsies; provided th...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
    MAY 04, 2016 | 1:00 PM
    Mammalian in vitro translation (cell-free) systems for rapid protein expression and production of therapeutic proteins
    Mammalian in vitro translation (cell-free) systems for rapid protein...
    In vitro translation (IVT) using mammalian cell extracts is a quick and convenient alternative to in vivo mammalian protein expression. Thermo Fisher has developed IVT systems from two mammal...
    Speaker: Penny Jensen, PhD , Govind Rao, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    MAY 04, 2016 | 5:00 AM
    Complete workflow solution from gene-to-protein
    Complete workflow solution from gene-to-protein
    Reliability from gene sequence to the expressed and purified protein is essential for many aspects of basic research and drug development. Thermo Fisher Scientific’s complete portfolio ...
    Speaker: Michael Spring
    Presented at: 2016 Gibco ExpressionWorld
    2
     
     
  • MAR 31, 2016 | 8:00 AM
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    DATE:  March 31, 2016 TIME:   8am PT, 11am ET, 4pm GMT In this webinar, you will learn:  Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
    Speaker: John Schiel, Ph.D.
    Sponsored By: Dharmacon, Dharmacon
    31 12
    FEB 03, 2016 | 3:00 PM
    Critical Appraisal of Animal Studies
    Critical Appraisal of Animal Studies
    Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
    Speaker: Annette O'Connor, BVSc, MVSc, DVSc, FACVSc
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 6:00 AM
    From the 3Rs to Systematic Reviews
    From the 3Rs to Systematic Reviews
    Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
    Speaker: Merel Ritskes-Hoitinga, DVM, PhD, Animal Welfare Officer, Dipl ECLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    4
    JAN 21, 2016 | 8:00 AM
    How to identify key genes with CRISPR-Cas9 and shRNA screens
    How to identify key genes with CRISPR-Cas9 and shRNA screens
    DATE:  January 21, 2016 TIME:   8am Pacific time, 11am Eastern time In this webinar, you will learn:  basics of pooled lentiviral screening workflows implications of ...
    Speaker: Anja Smith, PhD
    Sponsored By: Dharmacon, Dharmacon
    18 1
    AUG 20, 2014 | 2:15 PM
    Identifying transcriptional regulators of human embryonic development via expression variability
    Identifying transcriptional regulators of human embryonic development...
    Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
     
     
  • FEB 06, 2014 | 11:00 AM
    Formation of Bacterial Biofilms
    Formation of Bacterial Biofilms
    Biofilms, are defined as communities of microorganisms that grow embedded in a self-generated matrix of exopolysaccharides and adhered to an inert surface or a live tissue. They are formed 95...
    Speaker: Yvonne M Heuze de lcaza, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
    Resistance to AR Signaling Inhibitors in Castration Resistant...
    While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
    Speaker: Elahe A Mostaghel, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    AUG 21, 2013 | 10:00 AM
    C.E. CREDITS
    Azole resistance in Aspergillus fumigatus - clinical isolate screening, culture selection, and genetics
    Azole resistance in Aspergillus fumigatus - clinical isolate screening,...
    In the United States, invasive aspergillosis (IA), an invasive fungal infection of the upper respiratory tract of immune compromised patients, is usually caused by Aspergilus fumigatus, while...
    Speaker: William C Nierman, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    67
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