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    T-cell Receptor

    T-Cell Receptor: or TCR, is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex molecules.

    Webinars

    • MAY 21, 2019 | 7:00 AM
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
      DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
      Speaker: Eric Shifrut, PhD
      Sponsored By: Thermo Fisher Scientific
      10 1
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 6:00 AM
      The Role of Vaccination for the Treatment and Prevention of Breast and Ovarian Cancers
      The Role of Vaccination for the Treatment and Prevention of Breast...
      With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA.  Prior work has demonstrated that CD4 helper T c...
      Speaker: Keith Knutson, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      6
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      SEP 18, 2018 | 5:00 AM
      POSTER: Development of Multiplex xMAP Technology-Based Assays for Simultaneous Detection of Soluble Checkpoint Molecules Involved in Anti-Cancer Immune Response
      POSTER: Development of Multiplex xMAP Technology-Based Assays...
      To ensure the immune system’s balance between the recognition of non-self and the prevention of autoimmunity, the activity of immune cells needs to be strictly controlled. During the pr...
      Speaker: Susanne Oehler, PhD
      Presented at: 3rd Annual 7 Steps of Protein Virtual Event
      1
      SEP 13, 2018 | 1:30 PM
      Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
      Mechanisms of Antimicrobial Bioconversion by Environmental and...
      The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
      Speaker: Terence Crofts, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 12, 2018 | 8:00 AM
      Advancing precision immunotherapy through next generation sequencing of T-cell receptors: Part II
      Advancing precision immunotherapy through next generation sequencing...
      DATE:  September 12, 2018 TIME:  08:00am PDT, 11:00am EDT In the last presentation of this webinar series, we will continue our discussions on recent advancements i...
      Speaker: Timothy Looney, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      9
      AUG 16, 2018 | 8:00 AM
      Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
      Advancing precision immunotherapy through next-generation sequencing...
      DATE: August, 16, 2018TIME: 08:00AM PDTThis webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards...
      Speaker: Timothy Looney, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      7
      AUG 08, 2018 | 1:00 PM
      Deciphering the cancer immunity cycle through next generation sequencing
      Deciphering the cancer immunity cycle through next generation...
      DATE:  August 8, 2018 TIME:  1:00pm PDT, 4:00pm EDT To kick off our three-part immuno-oncology webinar series, Dr. Cawley will highlight recent advancements driven...
      Speaker: Simon Cawley, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      8 2
      MAY 30, 2018 | 10:30 AM
      Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
      Inhibitors of NSD2 Discovered by High-Throughput Screening with...
      NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
      Speaker: Nathan Coussens, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      APR 26, 2018 | 8:00 AM
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
      DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
      Speaker: Kristin Anderson, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      5
      FEB 21, 2018 | 6:00 AM
      Using HDAC Inhibitors to Improve Cancer Immunotherapy
      Using HDAC Inhibitors to Improve Cancer Immunotherapy
      We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
      Speaker: Alejandro Villagra, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      JAN 25, 2018 | 10:00 AM
      WEBINAR:  Engineered Viruses as Precision Cancer Therapeutics
      WEBINAR: Engineered Viruses as Precision Cancer Therapeutics
      DATE: January 25, 2018TIME: 10:00am PST, 1:00pm EST, 6:00pm GMTOncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehi...
      Speaker: Alexander Baker, MSci (Hons), 1st Class
      Sponsored By: Thermo Fisher Scientific/Gibco
      12
      DEC 12, 2017 | 10:00 AM
      WEBINAR: Gold Standards and innovative processes for DC research in immuno-oncology
      WEBINAR: Gold Standards and innovative processes for DC research...
      DATE: December 12, 2017TIME: 10:00AM PTSince their discovery, dendritic cells (DCs) have demonstrated a central role in the development of effective immune responses. Their unique abili...
      Speaker: Andrzej Dzionek, PhD
      Sponsored By: Miltenyi Biotec
      7
      NOV 07, 2017 | 10:00 AM
      WEBINAR: Chimeric Antigen Receptors: From proof of concept to widely applicable clinical research solutions
      WEBINAR: Chimeric Antigen Receptors: From proof of concept to...
      DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
      Speaker: Dina Schneider, B.Sc.Pharm, PhD
      Sponsored By: Miltenyi Biotec
      9 2
      OCT 26, 2017 | 12:00 PM
      WEBINAR: Overcoming Challenges in the Cellular Therapy Laboratory
      WEBINAR: Overcoming Challenges in the Cellular Therapy Laboratory
      DATE: October 26, 2017TIME: 12:00 PM PDTThis presentation will focus on recent advances in cellular therapy—from mesenchymal stromal cells (MSCs) to tumor-specific T-cells. More s...
      Speaker: Patrick Hanley, PhD
      Sponsored By: TERUMO BCT
      7
      OCT 25, 2017 | 10:00 AM
      WEBINAR: Antinuclear antibody screening - Making an informed decision
      WEBINAR: Antinuclear antibody screening - Making an informed decision
      DATE: October 25, 2017TIME: 10:00am PDT, 1:00pm EDTTesting for antinuclear antibodies (ANAs) has been a routine part of the evaluation of patients with a suspected connective tissue dis...
      Speaker: Gyorgy Abel, MD, PhD, DABCC , Melissa Snyder, PhD, DABCC
      Sponsored By: Bio-Rad Laboratories
      17 2
      OCT 19, 2017 | 8:00 AM
      New viral and non-viral platforms for T-cell engineering
      New viral and non-viral platforms for T-cell engineering
      Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than ever for curative effects. However, many technical challenges in T c...
      Speaker: Xavier de Mollerat du Jeu
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      OCT 19, 2017 | 8:00 AM
      WEBINAR: New viral and non-viral platforms for T-cell engineering
      WEBINAR: New viral and non-viral platforms for T-cell engineering
      DATE: October 19, 2017TIME: 08:00am PDT, 11:00am EDT Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than...
      Speaker: Xavier de Mollerat du Jeu
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      SEP 27, 2017 | 12:00 PM
      Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
      Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
      Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
      Speaker: Joshua Brody, MD
      Presented at: Cell Biology Virtual Event Series 2017
      2
      JUN 26, 2017 | 8:00 AM
      WEBINAR: Finding pathologic T cells in rheumatoid arthritis by mass cytometry
      WEBINAR: Finding pathologic T cells in rheumatoid arthritis by...
      Unfortunately due to technical issues this webinar has been delayed until June 26th. If you are unable to make the new time, it will be available on demand for you to view.DATE: June 26,...
      Speaker: Deepak Rao, MD, PhD , Michelle Poulin, PhD
      Sponsored By: Standard BioTools
      7 1
      APR 11, 2017 | 8:00 AM
      WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
      WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ...
      DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
      Speaker: Joshua Brody, MD , Michelle Poulin, PhD
      Sponsored By: Standard BioTools
      7 1
      DEC 14, 2016 | 7:30 AM
      Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
      Advances in modeling human diseases using induced pluripotent...
      DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
      Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      7 1
      NOV 02, 2016 | 10:30 AM
      Tough Targets. Simple Genotyping. Using HRM as a direct approach in research applications.
      Tough Targets. Simple Genotyping. Using HRM as a direct approach...
      Are there DNA targets in your lab that are difficult to genotype using standard PCR or sequencing?Do you ever need to genotype a single sample, and you don’t want to wait to batch sam...
      Speaker: Brian McNally, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
    MAY 21, 2019 | 7:00 AM
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
    DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
    Speaker: Eric Shifrut, PhD
    Sponsored By: Thermo Fisher Scientific
    10 1
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 6:00 AM
    The Role of Vaccination for the Treatment and Prevention of Breast and Ovarian Cancers
    The Role of Vaccination for the Treatment and Prevention of Breast...
    With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA.  Prior work has demonstrated that CD4 helper T c...
    Speaker: Keith Knutson, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    6
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
    SEP 18, 2018 | 5:00 AM
    POSTER: Development of Multiplex xMAP Technology-Based Assays for Simultaneous Detection of Soluble Checkpoint Molecules Involved in Anti-Cancer Immune Response
    POSTER: Development of Multiplex xMAP Technology-Based Assays...
    To ensure the immune system’s balance between the recognition of non-self and the prevention of autoimmunity, the activity of immune cells needs to be strictly controlled. During the pr...
    Speaker: Susanne Oehler, PhD
    Presented at: 3rd Annual 7 Steps of Protein Virtual Event
    1
     
     
  • SEP 13, 2018 | 1:30 PM
    Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
    Mechanisms of Antimicrobial Bioconversion by Environmental and...
    The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
    Speaker: Terence Crofts, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 12, 2018 | 8:00 AM
    Advancing precision immunotherapy through next generation sequencing of T-cell receptors: Part II
    Advancing precision immunotherapy through next generation sequencing...
    DATE:  September 12, 2018 TIME:  08:00am PDT, 11:00am EDT In the last presentation of this webinar series, we will continue our discussions on recent advancements i...
    Speaker: Timothy Looney, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    9
    AUG 16, 2018 | 8:00 AM
    Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
    Advancing precision immunotherapy through next-generation sequencing...
    DATE: August, 16, 2018TIME: 08:00AM PDTThis webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards...
    Speaker: Timothy Looney, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    7
    AUG 08, 2018 | 1:00 PM
    Deciphering the cancer immunity cycle through next generation sequencing
    Deciphering the cancer immunity cycle through next generation...
    DATE:  August 8, 2018 TIME:  1:00pm PDT, 4:00pm EDT To kick off our three-part immuno-oncology webinar series, Dr. Cawley will highlight recent advancements driven...
    Speaker: Simon Cawley, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    8 2
    MAY 30, 2018 | 10:30 AM
    Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
    Inhibitors of NSD2 Discovered by High-Throughput Screening with...
    NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
    Speaker: Nathan Coussens, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
     
     
  • APR 26, 2018 | 8:00 AM
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
    DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
    Speaker: Kristin Anderson, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    5
    FEB 21, 2018 | 6:00 AM
    Using HDAC Inhibitors to Improve Cancer Immunotherapy
    Using HDAC Inhibitors to Improve Cancer Immunotherapy
    We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
    Speaker: Alejandro Villagra, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    JAN 25, 2018 | 10:00 AM
    WEBINAR:  Engineered Viruses as Precision Cancer Therapeutics
    WEBINAR: Engineered Viruses as Precision Cancer Therapeutics
    DATE: January 25, 2018TIME: 10:00am PST, 1:00pm EST, 6:00pm GMTOncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehi...
    Speaker: Alexander Baker, MSci (Hons), 1st Class
    Sponsored By: Thermo Fisher Scientific/Gibco
    12
    DEC 12, 2017 | 10:00 AM
    WEBINAR: Gold Standards and innovative processes for DC research in immuno-oncology
    WEBINAR: Gold Standards and innovative processes for DC research...
    DATE: December 12, 2017TIME: 10:00AM PTSince their discovery, dendritic cells (DCs) have demonstrated a central role in the development of effective immune responses. Their unique abili...
    Speaker: Andrzej Dzionek, PhD
    Sponsored By: Miltenyi Biotec
    7
    NOV 07, 2017 | 10:00 AM
    WEBINAR: Chimeric Antigen Receptors: From proof of concept to widely applicable clinical research solutions
    WEBINAR: Chimeric Antigen Receptors: From proof of concept to...
    DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
    Speaker: Dina Schneider, B.Sc.Pharm, PhD
    Sponsored By: Miltenyi Biotec
    9 2
     
     
  • OCT 26, 2017 | 12:00 PM
    WEBINAR: Overcoming Challenges in the Cellular Therapy Laboratory
    WEBINAR: Overcoming Challenges in the Cellular Therapy Laboratory
    DATE: October 26, 2017TIME: 12:00 PM PDTThis presentation will focus on recent advances in cellular therapy—from mesenchymal stromal cells (MSCs) to tumor-specific T-cells. More s...
    Speaker: Patrick Hanley, PhD
    Sponsored By: TERUMO BCT
    7
    OCT 25, 2017 | 10:00 AM
    WEBINAR: Antinuclear antibody screening - Making an informed decision
    WEBINAR: Antinuclear antibody screening - Making an informed decision
    DATE: October 25, 2017TIME: 10:00am PDT, 1:00pm EDTTesting for antinuclear antibodies (ANAs) has been a routine part of the evaluation of patients with a suspected connective tissue dis...
    Speaker: Gyorgy Abel, MD, PhD, DABCC , Melissa Snyder, PhD, DABCC
    Sponsored By: Bio-Rad Laboratories
    17 2
    OCT 19, 2017 | 8:00 AM
    New viral and non-viral platforms for T-cell engineering
    New viral and non-viral platforms for T-cell engineering
    Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than ever for curative effects. However, many technical challenges in T c...
    Speaker: Xavier de Mollerat du Jeu
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    OCT 19, 2017 | 8:00 AM
    WEBINAR: New viral and non-viral platforms for T-cell engineering
    WEBINAR: New viral and non-viral platforms for T-cell engineering
    DATE: October 19, 2017TIME: 08:00am PDT, 11:00am EDT Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than...
    Speaker: Xavier de Mollerat du Jeu
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    SEP 27, 2017 | 12:00 PM
    Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
    Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
    Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
    Speaker: Joshua Brody, MD
    Presented at: Cell Biology Virtual Event Series 2017
    2
     
     
  • JUN 26, 2017 | 8:00 AM
    WEBINAR: Finding pathologic T cells in rheumatoid arthritis by mass cytometry
    WEBINAR: Finding pathologic T cells in rheumatoid arthritis by...
    Unfortunately due to technical issues this webinar has been delayed until June 26th. If you are unable to make the new time, it will be available on demand for you to view.DATE: June 26,...
    Speaker: Deepak Rao, MD, PhD , Michelle Poulin, PhD
    Sponsored By: Standard BioTools
    7 1
    APR 11, 2017 | 8:00 AM
    WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ Vaccination
    WEBINAR: Enhancing Checkpoint Blockade in Lymphoma with In Situ...
    DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
    Speaker: Joshua Brody, MD , Michelle Poulin, PhD
    Sponsored By: Standard BioTools
    7 1
    DEC 14, 2016 | 7:30 AM
    Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
    Advances in modeling human diseases using induced pluripotent...
    DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
    Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    7 1
    NOV 02, 2016 | 10:30 AM
    Tough Targets. Simple Genotyping. Using HRM as a direct approach in research applications.
    Tough Targets. Simple Genotyping. Using HRM as a direct approach...
    Are there DNA targets in your lab that are difficult to genotype using standard PCR or sequencing?Do you ever need to genotype a single sample, and you don’t want to wait to batch sam...
    Speaker: Brian McNally, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
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