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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • SEP 13, 2018 | 6:00 AM
      The Hurricane Microbiome Project: Environmental Exposures and Population Health
      The Hurricane Microbiome Project: Environmental Exposures and...
      The Alkek Center for Metagenomics and Microbiome Research (CMMR) at Baylor College of Medicine is pursuing numerous research and development efforts in the study of how the microbiome impacts...
      Speaker: Joseph Petrosino, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      1
      SEP 13, 2018 | 6:00 AM
      The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
      The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
      In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data...
      Speaker: Siobain Duffy, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      1
      SEP 12, 2018 | 10:30 AM
      Bacteria that Eat Electricity: Understanding Biocathodes Using Culture Independent Techniques
      Bacteria that Eat Electricity: Understanding Biocathodes Using...
      Some bacteria can use an electrode as an electron donor for respiration, generating an electrical current in the process. We are trying to understand a bacterial community that uses electrici...
      Speaker: Brian Eddie, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      2 1
      AUG 01, 2018 | 12:00 AM
      Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
      Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
      Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
      Speaker: Kapil Bharti
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUL 19, 2018 | 9:00 AM
      Investigating the role of microRNAs in pancreatic cancer progression
      Investigating the role of microRNAs in pancreatic cancer progression
      DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
      Speaker: Silvia Ottaviani, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 5
      JUN 29, 2018 | 9:00 AM
      Diet and gene interactions in the control of central cell metabolism
      Diet and gene interactions in the control of central cell metabolism
      DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
      Speaker: Sophie Prosolek
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 2
      JUN 26, 2018 | 9:00 AM
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
      Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
      Speaker: Laura Schaevitz, PhD
      Sponsored By: Vium
      6
      JUN 07, 2018 | 7:00 AM
      How microCT Can Provide Insight into Dynamic Disease Processes
      How microCT Can Provide Insight into Dynamic Disease Processes
      DATE: June 7, 2018TIME: 07:00AM PDT, 4:00PM CESTIn this webinar, Prof. Greetje Vande Velde will give an overview of her work, which involves lung and brain infections.  Dr Vande Ve...
      Speaker: Greetje Vande Velde
      Sponsored By: Bruker Microbiology & Diagnostics
      4 1
      MAY 30, 2018 | 6:00 AM
      Phenotypic Profiling for Improving Drug Discovery Productivity
      Phenotypic Profiling for Improving Drug Discovery Productivity
      The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
      Speaker: Ellen Berg, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2 1
      MAY 22, 2018 | 8:00 AM
      Drug development with nuclear receptor knockout and humanized rat models
      Drug development with nuclear receptor knockout and humanized...
      DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
      Speaker: Kevin Forbes, PhD , Andrew Brown, MS
      Sponsored By: Horizon Discovery
      5
      MAY 10, 2018 | 6:00 AM
      Differential Abundance Analysis for Microbial Marker-Gene Surveys
      Differential Abundance Analysis for Microbial Marker-Gene Surveys
      We introduce a differential abundance analysis method for the analysis of sparse high-throughput data from large-scale surveys of marker genes for microbial communities. Our approach relies o...
      Speaker: Joseph Paulson, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      2
      MAY 09, 2018 | 1:30 PM
      Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
      Next-Generation Sequencing to Understand the Function of miRNAs...
      There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
      Speaker: Ulrich Broeckel, MD , Amy Turner, BS
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      MAY 09, 2018 | 12:00 PM
      Using Genome Wide Sequencing to Identify a Gene-Gene Interaction
      Using Genome Wide Sequencing to Identify a Gene-Gene Interaction
      In this presentation I will describe results from a family study designed to identify the genetic cause for familial clustering of several early onset cancers.   Data from next generatio...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 09, 2018 | 10:30 AM
      C.E. CREDITS
      Finding Coherence in Chaos by Embracing Evolution and Complexity
      Finding Coherence in Chaos by Embracing Evolution and Complexity
      Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology.   Examination of molecular networks and their dynamic behavior o...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      APR 26, 2018 | 8:00 AM
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
      DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
      Speaker: Kristin Anderson, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      5
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      APR 11, 2018 | 1:30 PM
      Community Pharmacy-Based Disease Management Programs Using Point-of-Care Tests
      Community Pharmacy-Based Disease Management Programs Using Point-of-Care...
      The availability of CLIA-waived point-of-care tests and the accessibility and training of community pharmacists creates an opportunity for the development of collaborative disease management...
      Speaker: Donald Klepser, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      MAR 27, 2018 | 9:00 AM
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
      Speaker: Amanda Haas
      Sponsored By: Horizon Discovery
      23 15
      MAR 22, 2018 | 9:00 AM
      Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
      Differentiation sensitizes stem-like glioblastoma tumor-initiating...
      DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
      Speaker: Jasmine Hughes
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 4
      MAR 22, 2018 | 7:00 AM
      Emerging Diagnostic Strategies to Support C. difficile Infection Control
      Emerging Diagnostic Strategies to Support C. difficile Infection...
      DATE: March 22, 2018TIME: 07:00am PDT, 10:00am EDTClostridium difficile (C. diff) is a highly problematic healthcare-associated infection that is easily spread and often results in poor...
      Speaker: Lance Peterson, MD, FASCP, FIDSA, FAAM, FSHEA
      Sponsored By: Roche Diagnostics
      8
      MAR 15, 2018 | 1:30 PM
      Rare Inherited Mutations in Autism Spectrum Disorder
      Rare Inherited Mutations in Autism Spectrum Disorder
      Autism spectrum disorder (ASD) is a complex group of individually rare neurological conditions with genetic and non-genetic causes. Despite the strong genetic component of ASD, it has been ve...
      Speaker: Maria Chahrour, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
      MAR 15, 2018 | 10:30 AM
      An Emerging Role of DNA Damage-Repair in Huntington's Disease
      An Emerging Role of DNA Damage-Repair in Huntington's Disease
      Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
      Speaker: Animesh Ray, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
      MAR 15, 2018 | 10:30 AM
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
      The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
      Speaker: Jill Weimer, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      MAR 15, 2018 | 10:30 AM
      Investigating Consciousness with Closed-Loop Neural Reinforcement
      Investigating Consciousness with Closed-Loop Neural Reinforcement
      In consciousness studies, a longstanding controversy concerns whether activity in the prefrontal cortical (PFC) region of the brain is necessary to evoke conscious experiences. Similarly, the...
      Speaker: Aurelio Cortese, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
    SEP 13, 2018 | 6:00 AM
    The Hurricane Microbiome Project: Environmental Exposures and Population Health
    The Hurricane Microbiome Project: Environmental Exposures and...
    The Alkek Center for Metagenomics and Microbiome Research (CMMR) at Baylor College of Medicine is pursuing numerous research and development efforts in the study of how the microbiome impacts...
    Speaker: Joseph Petrosino, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    1
    SEP 13, 2018 | 6:00 AM
    The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
    The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
    In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data...
    Speaker: Siobain Duffy, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    1
    SEP 12, 2018 | 10:30 AM
    Bacteria that Eat Electricity: Understanding Biocathodes Using Culture Independent Techniques
    Bacteria that Eat Electricity: Understanding Biocathodes Using...
    Some bacteria can use an electrode as an electron donor for respiration, generating an electrical current in the process. We are trying to understand a bacterial community that uses electrici...
    Speaker: Brian Eddie, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    2 1
    AUG 01, 2018 | 12:00 AM
    Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
    Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
    Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
    Speaker: Kapil Bharti
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    JUL 19, 2018 | 9:00 AM
    Investigating the role of microRNAs in pancreatic cancer progression
    Investigating the role of microRNAs in pancreatic cancer progression
    DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
    Speaker: Silvia Ottaviani, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 5
     
     
  • JUN 29, 2018 | 9:00 AM
    Diet and gene interactions in the control of central cell metabolism
    Diet and gene interactions in the control of central cell metabolism
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Speaker: Sophie Prosolek
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 2
    JUN 26, 2018 | 9:00 AM
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
    Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
    Speaker: Laura Schaevitz, PhD
    Sponsored By: Vium
    6
    JUN 07, 2018 | 7:00 AM
    How microCT Can Provide Insight into Dynamic Disease Processes
    How microCT Can Provide Insight into Dynamic Disease Processes
    DATE: June 7, 2018TIME: 07:00AM PDT, 4:00PM CESTIn this webinar, Prof. Greetje Vande Velde will give an overview of her work, which involves lung and brain infections.  Dr Vande Ve...
    Speaker: Greetje Vande Velde
    Sponsored By: Bruker Microbiology & Diagnostics
    4 1
    MAY 30, 2018 | 6:00 AM
    Phenotypic Profiling for Improving Drug Discovery Productivity
    Phenotypic Profiling for Improving Drug Discovery Productivity
    The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
    Speaker: Ellen Berg, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2 1
    MAY 22, 2018 | 8:00 AM
    Drug development with nuclear receptor knockout and humanized rat models
    Drug development with nuclear receptor knockout and humanized...
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    Speaker: Kevin Forbes, PhD , Andrew Brown, MS
    Sponsored By: Horizon Discovery
    5
     
     
  • MAY 10, 2018 | 6:00 AM
    Differential Abundance Analysis for Microbial Marker-Gene Surveys
    Differential Abundance Analysis for Microbial Marker-Gene Surveys
    We introduce a differential abundance analysis method for the analysis of sparse high-throughput data from large-scale surveys of marker genes for microbial communities. Our approach relies o...
    Speaker: Joseph Paulson, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    2
    MAY 09, 2018 | 1:30 PM
    Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
    Next-Generation Sequencing to Understand the Function of miRNAs...
    There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
    Speaker: Ulrich Broeckel, MD , Amy Turner, BS
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    MAY 09, 2018 | 12:00 PM
    Using Genome Wide Sequencing to Identify a Gene-Gene Interaction
    Using Genome Wide Sequencing to Identify a Gene-Gene Interaction
    In this presentation I will describe results from a family study designed to identify the genetic cause for familial clustering of several early onset cancers.   Data from next generatio...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    MAY 09, 2018 | 10:30 AM
    C.E. CREDITS
    Finding Coherence in Chaos by Embracing Evolution and Complexity
    Finding Coherence in Chaos by Embracing Evolution and Complexity
    Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology.   Examination of molecular networks and their dynamic behavior o...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    APR 26, 2018 | 8:00 AM
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
    DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
    Speaker: Kristin Anderson, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    5
     
     
  • APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    APR 11, 2018 | 1:30 PM
    Community Pharmacy-Based Disease Management Programs Using Point-of-Care Tests
    Community Pharmacy-Based Disease Management Programs Using Point-of-Care...
    The availability of CLIA-waived point-of-care tests and the accessibility and training of community pharmacists creates an opportunity for the development of collaborative disease management...
    Speaker: Donald Klepser, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    MAR 27, 2018 | 9:00 AM
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
    Speaker: Amanda Haas
    Sponsored By: Horizon Discovery
    23 15
    MAR 22, 2018 | 9:00 AM
    Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
    Differentiation sensitizes stem-like glioblastoma tumor-initiating...
    DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
    Speaker: Jasmine Hughes
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 4
    MAR 22, 2018 | 7:00 AM
    Emerging Diagnostic Strategies to Support C. difficile Infection Control
    Emerging Diagnostic Strategies to Support C. difficile Infection...
    DATE: March 22, 2018TIME: 07:00am PDT, 10:00am EDTClostridium difficile (C. diff) is a highly problematic healthcare-associated infection that is easily spread and often results in poor...
    Speaker: Lance Peterson, MD, FASCP, FIDSA, FAAM, FSHEA
    Sponsored By: Roche Diagnostics
    8
     
     
  • MAR 15, 2018 | 1:30 PM
    Rare Inherited Mutations in Autism Spectrum Disorder
    Rare Inherited Mutations in Autism Spectrum Disorder
    Autism spectrum disorder (ASD) is a complex group of individually rare neurological conditions with genetic and non-genetic causes. Despite the strong genetic component of ASD, it has been ve...
    Speaker: Maria Chahrour, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
    MAR 15, 2018 | 10:30 AM
    An Emerging Role of DNA Damage-Repair in Huntington's Disease
    An Emerging Role of DNA Damage-Repair in Huntington's Disease
    Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
    Speaker: Animesh Ray, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
    MAR 15, 2018 | 10:30 AM
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
    The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
    Speaker: Jill Weimer, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    MAR 15, 2018 | 10:30 AM
    Investigating Consciousness with Closed-Loop Neural Reinforcement
    Investigating Consciousness with Closed-Loop Neural Reinforcement
    In consciousness studies, a longstanding controversy concerns whether activity in the prefrontal cortical (PFC) region of the brain is necessary to evoke conscious experiences. Similarly, the...
    Speaker: Aurelio Cortese, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
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