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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • OCT 25, 2018 | 10:30 AM
      Trash or Treasure: Optimizing Titration Electrodes and Consumables
      Trash or Treasure: Optimizing Titration Electrodes and Consumables
      Everyone that uses titration in their lab knows how simple and fast the technique can be.  However, uncertainty around when to replace electrodes creates confusion. Reagent quality, tubi...
      Speaker: Jessica McVay , Lori Spafford
      Presented at: Analytical Chemistry Virtual Event Series 2018
      Sponsored By: Metrohm USA
      1
      OCT 25, 2018 | 8:00 AM
      Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
      Disease modeling and cancer therapy in stem cell-derived 3D organoid...
      DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
      Speaker: Devanjali Dutta, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      OCT 24, 2018 | 1:30 PM
      Accessories and Techniques for FT-IR Sample Analysis
      Accessories and Techniques for FT-IR Sample Analysis
      This intensive workshop will introduce infrared spectroscopy, outline the various sample handling methods and provide guidance on the numerous transmission and reflectance methods available f...
      Speaker: Richard Larsen, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      OCT 24, 2018 | 9:00 AM
      Keynote Presentation: Solid Phase Microextraction: New Developments in Bioanalysis and Medical Applications
      Keynote Presentation: Solid Phase Microextraction: New Developments...
      Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
      Speaker: Barbara Bojko, PhD , Janusz Pawliszyn, PhD, FCIC, FRSC
      Presented at: Analytical Chemistry Virtual Event Series 2018
      2
      OCT 24, 2018 | 7:30 AM
      Keynote Presentation: Mass Spectrometry Approaches for the the Single Cell Chemical Characterization of the Brain
      Keynote Presentation: Mass Spectrometry Approaches for the the...
      In the postgenomic era, one expects the suite of chemical players in a brain region to be known and their functions uncovered. Perhaps surprisingly, many neurochemicals remain poorly characte...
      Speaker: Jonathan Sweedler, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      3
      OCT 24, 2018 | 6:00 AM
      Applied Hyperspectral Imaging Fundamentals and Case Studies
      Applied Hyperspectral Imaging Fundamentals and Case Studies
      A fast, reliable and low cost characterization of materials/ products as fed to a process, and/or resulting from different processing actions, represents one of the most challenging targets i...
      Speaker: Giuseppe Bonifazi, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      2
      OCT 23, 2018 | 7:00 AM
      FLIPR 1536-well application in high throughput screening
      FLIPR 1536-well application in high throughput screening
      DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
      Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
      Sponsored By: Molecular Devices
      4
      OCT 11, 2018 | 12:00 PM
      Aurora Kinase A Drives The Evolution of Resistance to Third Generation EGFR Inhibitors in Lung Cancer
      Aurora Kinase A Drives The Evolution of Resistance to Third Generation...
      Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between...
      Speaker: Khyati Shah, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 1:30 PM
      Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
      Discovery of Biomarkers Predictive of Anticancer Drug Response...
      Some Abstract...
      Speaker: Benjamin Haibe-Kains, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 10:30 AM
      Microbiome Signatures in Gynecologic Cancers
      Microbiome Signatures in Gynecologic Cancers
      The microbiome signatures in the context of gynecologic cancers (endometrial and ovarian) and the potential for their clinical use will be discussed. The use of microfluidic technologies to i...
      Speaker: Marina Walther-Antonio, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      3
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 03, 2018 | 12:00 PM
      Using CRISPR and Stem Cells to Treat Genetic Disease
      Using CRISPR and Stem Cells to Treat Genetic Disease
      Decoding human genetic disease allows us to develop models of the pathology that can be directly tested with gene correction or targeted drug therapy.  Dominant negative mutations are pa...
      Speaker: Bruce Conklin, MD
      Presented at: CRISPR Virtual Event Series 2018
      1
      OCT 03, 2018 | 10:30 AM
      Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
      Integrating Novel Advances in Gene Delivery and Genome Engineering...
      There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
      Speaker: David Schaffer, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      SEP 27, 2018 | 1:30 PM
      Cilia Abnormalities and Developmental Defects in Lowe Syndrome
      Cilia Abnormalities and Developmental Defects in Lowe Syndrome
      Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
      Speaker: R. Claudio Aguilar, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      2
      SEP 20, 2018 | 8:00 AM
      Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
      Cardiovascular Disease: Applying MRI to study atherosclerosis,...
       DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
      Speaker: Claudia Calcagno Mani, MD, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      10
      SEP 20, 2018 | 1:00 AM
      Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
      Cardiovascular Disease: Applying MRI to study atherosclerosis,...
      DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
      Speaker: Claudia Calcagno Mani, MD, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      6 1
      SEP 18, 2018 | 11:00 AM
      WEBINAR: ProQuantum high-sensitivity immunoassays offer minimum sample consumption with maximum performance
      WEBINAR: ProQuantum high-sensitivity immunoassays offer minimum...
      Early detection of protein biomarkers is critical to the study of human diseases, yet current tools available for low-level protein quantitation do not address all the needs for protein and m...
      Speaker: David Bourdon, Ph.D
      Presented at: 3rd Annual 7 Steps of Protein Virtual Event
      1
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      SEP 13, 2018 | 1:30 PM
      Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
      Mechanisms of Antimicrobial Bioconversion by Environmental and...
      The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
      Speaker: Terence Crofts, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 13, 2018 | 10:30 AM
      Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic Resistance
      Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic...
      Horizontal gene transfer (HGT) – or the non-genealogical transmission of DNA between organisms – is the dominant mode responsible for the spread of antibiotic resistance genes. Co...
      Speaker: Allison Lopatkin, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 13, 2018 | 10:30 AM
      Studying Environmental Sensing and Response in a Bacterial Plant Pathogen - Inside Out
      Studying Environmental Sensing and Response in a Bacterial Plant...
      The bacterium Pantoea stewartii subsp. stewartii causes Stewart’s wilt disease in corn and serves as a model for other xylem-dwelling phytopathogens. P. stewartii is transmitted to plan...
      Speaker: Ann Stevens, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
    OCT 25, 2018 | 10:30 AM
    Trash or Treasure: Optimizing Titration Electrodes and Consumables
    Trash or Treasure: Optimizing Titration Electrodes and Consumables
    Everyone that uses titration in their lab knows how simple and fast the technique can be.  However, uncertainty around when to replace electrodes creates confusion. Reagent quality, tubi...
    Speaker: Jessica McVay , Lori Spafford
    Presented at: Analytical Chemistry Virtual Event Series 2018
    Sponsored By: Metrohm USA
    1
    OCT 25, 2018 | 8:00 AM
    Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
    Disease modeling and cancer therapy in stem cell-derived 3D organoid...
    DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
    Speaker: Devanjali Dutta, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    OCT 24, 2018 | 1:30 PM
    Accessories and Techniques for FT-IR Sample Analysis
    Accessories and Techniques for FT-IR Sample Analysis
    This intensive workshop will introduce infrared spectroscopy, outline the various sample handling methods and provide guidance on the numerous transmission and reflectance methods available f...
    Speaker: Richard Larsen, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
    OCT 24, 2018 | 9:00 AM
    Keynote Presentation: Solid Phase Microextraction: New Developments in Bioanalysis and Medical Applications
    Keynote Presentation: Solid Phase Microextraction: New Developments...
    Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
    Speaker: Barbara Bojko, PhD , Janusz Pawliszyn, PhD, FCIC, FRSC
    Presented at: Analytical Chemistry Virtual Event Series 2018
    2
    OCT 24, 2018 | 7:30 AM
    Keynote Presentation: Mass Spectrometry Approaches for the the Single Cell Chemical Characterization of the Brain
    Keynote Presentation: Mass Spectrometry Approaches for the the...
    In the postgenomic era, one expects the suite of chemical players in a brain region to be known and their functions uncovered. Perhaps surprisingly, many neurochemicals remain poorly characte...
    Speaker: Jonathan Sweedler, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    3
     
     
  • OCT 24, 2018 | 6:00 AM
    Applied Hyperspectral Imaging Fundamentals and Case Studies
    Applied Hyperspectral Imaging Fundamentals and Case Studies
    A fast, reliable and low cost characterization of materials/ products as fed to a process, and/or resulting from different processing actions, represents one of the most challenging targets i...
    Speaker: Giuseppe Bonifazi, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    2
    OCT 23, 2018 | 7:00 AM
    FLIPR 1536-well application in high throughput screening
    FLIPR 1536-well application in high throughput screening
    DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
    Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
    Sponsored By: Molecular Devices
    4
    OCT 11, 2018 | 12:00 PM
    Aurora Kinase A Drives The Evolution of Resistance to Third Generation EGFR Inhibitors in Lung Cancer
    Aurora Kinase A Drives The Evolution of Resistance to Third Generation...
    Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between...
    Speaker: Khyati Shah, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 1:30 PM
    Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
    Discovery of Biomarkers Predictive of Anticancer Drug Response...
    Some Abstract...
    Speaker: Benjamin Haibe-Kains, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 10:30 AM
    Microbiome Signatures in Gynecologic Cancers
    Microbiome Signatures in Gynecologic Cancers
    The microbiome signatures in the context of gynecologic cancers (endometrial and ovarian) and the potential for their clinical use will be discussed. The use of microfluidic technologies to i...
    Speaker: Marina Walther-Antonio, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    3
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
    OCT 03, 2018 | 12:00 PM
    Using CRISPR and Stem Cells to Treat Genetic Disease
    Using CRISPR and Stem Cells to Treat Genetic Disease
    Decoding human genetic disease allows us to develop models of the pathology that can be directly tested with gene correction or targeted drug therapy.  Dominant negative mutations are pa...
    Speaker: Bruce Conklin, MD
    Presented at: CRISPR Virtual Event Series 2018
    1
     
     
  • OCT 03, 2018 | 10:30 AM
    Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
    Integrating Novel Advances in Gene Delivery and Genome Engineering...
    There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
    Speaker: David Schaffer, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    SEP 27, 2018 | 1:30 PM
    Cilia Abnormalities and Developmental Defects in Lowe Syndrome
    Cilia Abnormalities and Developmental Defects in Lowe Syndrome
    Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
    Speaker: R. Claudio Aguilar, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    2
    SEP 20, 2018 | 8:00 AM
    Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
    Cardiovascular Disease: Applying MRI to study atherosclerosis,...
     DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
    Speaker: Claudia Calcagno Mani, MD, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    10
    SEP 20, 2018 | 1:00 AM
    Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
    Cardiovascular Disease: Applying MRI to study atherosclerosis,...
    DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
    Speaker: Claudia Calcagno Mani, MD, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    6 1
    SEP 18, 2018 | 11:00 AM
    WEBINAR: ProQuantum high-sensitivity immunoassays offer minimum sample consumption with maximum performance
    WEBINAR: ProQuantum high-sensitivity immunoassays offer minimum...
    Early detection of protein biomarkers is critical to the study of human diseases, yet current tools available for low-level protein quantitation do not address all the needs for protein and m...
    Speaker: David Bourdon, Ph.D
    Presented at: 3rd Annual 7 Steps of Protein Virtual Event
    1
     
     
  • SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
    SEP 13, 2018 | 1:30 PM
    Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
    Mechanisms of Antimicrobial Bioconversion by Environmental and...
    The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
    Speaker: Terence Crofts, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 13, 2018 | 10:30 AM
    Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic Resistance
    Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic...
    Horizontal gene transfer (HGT) – or the non-genealogical transmission of DNA between organisms – is the dominant mode responsible for the spread of antibiotic resistance genes. Co...
    Speaker: Allison Lopatkin, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 13, 2018 | 10:30 AM
    Studying Environmental Sensing and Response in a Bacterial Plant Pathogen - Inside Out
    Studying Environmental Sensing and Response in a Bacterial Plant...
    The bacterium Pantoea stewartii subsp. stewartii causes Stewart’s wilt disease in corn and serves as a model for other xylem-dwelling phytopathogens. P. stewartii is transmitted to plan...
    Speaker: Ann Stevens, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
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