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    Epigenetics

    Epigenetics: the study of heritable changes in gene function that do not involve changes in the DNA sequence. Epigenetics often refers to changes in a chromosome that affect gene activity and expression, but can also be used to describe any heritable phenotypic change that does not derive from a modification of the genome, such as prions. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal developmental program. The standard definition of epigenetics requires these alterations to be heritable, either in the progeny of cells or of organisms.

    Webinars

    • APR 17, 2019 | 9:00 AM
      You've cultured an organoid and spheroid... now what?
      You've cultured an organoid and spheroid... now what?
      DATE:  April 17, 2019TIME:  9:00am PDT...
      Speaker: Takanori Takebe
      Sponsored By: Thermo Fisher Scientific
      5
      APR 03, 2019 | 9:00 AM
      How to analyze/characterize your 3D culture
      How to analyze/characterize your 3D culture
      DATE:  April 3, 2019TIME:  9:00am PDT...
      Speaker: Chris Langsdorf
      Sponsored By: Thermo Fisher Scientific
      6
      MAR 28, 2019 | 12:00 PM
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
      Speaker: Debra Kimless, MD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      6
      MAR 20, 2019 | 9:00 AM
      Getting started in 3D - Setting up your lab and reviewing common pitfalls of researchers new to 3D
      Getting started in 3D - Setting up your lab and reviewing common...
      DATE:  March 20, 2019TIME:  9:00am PDT...
      Speaker: Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      7
      FEB 20, 2019 | 9:00 AM
      Choosing the best system to answer your question - What question are you looking to answer?
      Choosing the best system to answer your question - What question...
      DATE:  February 20, 2019TIME:  9:00am PST  ...
      Speaker: David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      15 1
      DEC 06, 2018 | 7:00 AM
      Image-based screening for precision medicine and immunotherapy
      Image-based screening for precision medicine and immunotherapy
      DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
      Speaker: Dr. Gregory Vladimer
      Sponsored By: Revvity
      6
      OCT 31, 2018 | 8:00 AM
      Chromatin immunoprecipitation: Five steps to great results
      Chromatin immunoprecipitation: Five steps to great results
      DATE: October 31, 2018TIME: 8:00AM PDTChromatin immunoprecipitation (ChIP) is a technique researchers employ to obtain a snapshot of protein-DNA interactions in the cell.  ChI...
      Speaker: Eliza Small, PhD
      Sponsored By: Thermo Fisher Scientific
      10
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 03, 2018 | 12:00 PM
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
      Speaker: Dipali Sashital, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
      OCT 03, 2018 | 9:00 AM
      CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs in CRISPR-Cas9 Genome-Editing Systems
      CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs...
      The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
      Speaker: Lihua Julie Zhu, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      AUG 01, 2018 | 12:00 AM
      Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
      Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
      Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
      Speaker: Kapil Bharti
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUN 27, 2018 | 8:00 AM
      Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize success
      Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize...
      DATE: June 27, 2018TIME: 08:00AM PDT CRISPR-Cas9 is a very versatile tool to discover more about your pathway or gene of interest. Its simplicity has led to an explosion in a...
      Speaker: Laura Carleton, PhD
      Sponsored By: Horizon Discovery
      13 1
      MAY 03, 2018 | 11:00 AM
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
      DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
      Speaker: Sisi Li
      Sponsored By: Covaris
      5 2
      APR 12, 2018 | 10:30 AM
      The Genome in 3D: A Clinical Biomarker Platform
      The Genome in 3D: A Clinical Biomarker Platform
      In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
      Speaker: Kevin Little, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
    APR 17, 2019 | 9:00 AM
    You've cultured an organoid and spheroid... now what?
    You've cultured an organoid and spheroid... now what?
    DATE:  April 17, 2019TIME:  9:00am PDT...
    Speaker: Takanori Takebe
    Sponsored By: Thermo Fisher Scientific
    5
    APR 03, 2019 | 9:00 AM
    How to analyze/characterize your 3D culture
    How to analyze/characterize your 3D culture
    DATE:  April 3, 2019TIME:  9:00am PDT...
    Speaker: Chris Langsdorf
    Sponsored By: Thermo Fisher Scientific
    6
    MAR 28, 2019 | 12:00 PM
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
    Speaker: Debra Kimless, MD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    6
    MAR 20, 2019 | 9:00 AM
    Getting started in 3D - Setting up your lab and reviewing common pitfalls of researchers new to 3D
    Getting started in 3D - Setting up your lab and reviewing common...
    DATE:  March 20, 2019TIME:  9:00am PDT...
    Speaker: Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    7
    FEB 20, 2019 | 9:00 AM
    Choosing the best system to answer your question - What question are you looking to answer?
    Choosing the best system to answer your question - What question...
    DATE:  February 20, 2019TIME:  9:00am PST  ...
    Speaker: David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
    15 1
     
     
  • DEC 06, 2018 | 7:00 AM
    Image-based screening for precision medicine and immunotherapy
    Image-based screening for precision medicine and immunotherapy
    DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
    Speaker: Dr. Gregory Vladimer
    Sponsored By: Revvity
    6
    OCT 31, 2018 | 8:00 AM
    Chromatin immunoprecipitation: Five steps to great results
    Chromatin immunoprecipitation: Five steps to great results
    DATE: October 31, 2018TIME: 8:00AM PDTChromatin immunoprecipitation (ChIP) is a technique researchers employ to obtain a snapshot of protein-DNA interactions in the cell.  ChI...
    Speaker: Eliza Small, PhD
    Sponsored By: Thermo Fisher Scientific
    10
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
    OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 03, 2018 | 12:00 PM
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
    Speaker: Dipali Sashital, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
    OCT 03, 2018 | 9:00 AM
    CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs in CRISPR-Cas9 Genome-Editing Systems
    CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs...
    The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
    Speaker: Lihua Julie Zhu, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
     
     
  • AUG 01, 2018 | 12:00 AM
    Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
    Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
    Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
    Speaker: Kapil Bharti
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    JUN 27, 2018 | 8:00 AM
    Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize success
    Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize...
    DATE: June 27, 2018TIME: 08:00AM PDT CRISPR-Cas9 is a very versatile tool to discover more about your pathway or gene of interest. Its simplicity has led to an explosion in a...
    Speaker: Laura Carleton, PhD
    Sponsored By: Horizon Discovery
    13 1
    MAY 03, 2018 | 11:00 AM
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    Speaker: Sisi Li
    Sponsored By: Covaris
    5 2
    APR 12, 2018 | 10:30 AM
    The Genome in 3D: A Clinical Biomarker Platform
    The Genome in 3D: A Clinical Biomarker Platform
    In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
    Speaker: Kevin Little, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
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