Gene: is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function.
Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. In early 2016 we developed a pipe...
Fusion genes are hybrid genes formed by the fusion of two separate genes. Translocation, interstitial deletion and chromosomal inversions are some of the genetic events that can lead to the f...
Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades. Next-Generation Sequencing (NGS) technology r...
Vitamin D insufficiency and deficiency are prevalent worldwide, and pregnant women and infants are at highest risk for having deficiency and related consequences. Epidemiologic studies have s...
DATE: October 19, 2016
TIME: 9:00 AM PT, 12:00 PM ET, 6:00 PM CEST
Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
Induced pluripotent stem cells derived from patient cells have emerged as complementary tools to study human neurological disorders. Neurxstem Inc has generated human iPSC-derived synth...
Cell Sciences Innovation, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ USA
In vitro translational models play a critical role in the drug discovery process because t...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
Intra-tumor heterogeneity is a major obstacle to cancer treatment. Existing single-cell studies of intra-tumor heterogeneity have largely focused on DNA mutations; functional heterogeneity is...
Circulating Tumor Cells (CTCs) have been extensively explored as circulating biomarkers in various cancers. Due to their rarity, heterogeneity and stem cell-like properties, detecting and pro...
Real-time multiplex PCR assays are potentially the most rapid, most sensitive,and least expensive way to assess the abundance of mutant DNA fragments present in liquid biopsies; provided th...
Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
Tumor heterogeneity has been known for a while but quantifying heterogeneity is still a challenge. NGS is the method of choice in the analysis of tumor heterogeneity, however, there are...
PRESENTED BY:DATE: September 29, 2016TIME: 8:00AM PT, 11AM ETInterest in 3D cell culture has grown exponentially in recent years, partially due to 3D cultures hel...
ME/CFS is a debilitating disease with a controversial history and multiple names. The Institute of Medicine recently recommended renaming the disease “Systemic Exertion Intoleranc...
Our speaker, Wenjie Xu, Ph.D., will present his publication data demonstrating how nCounter® technology can advance your infectious disease research faster and more accurately with unprec...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and va...
In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
The study of human genetic neurodevelopmental disorders (NDDs) is complicated by the inaccessibility of the relevant tissue for study: it is extremely rare to obtain post-surgical brain sampl...
Over the last 15 years, human pluripotent stem cell (hPSC) technologies have progressed from academic curiosities into tools with the promise to underpin commerce, leading to real progress in...
PrPC is a conserved lipid-raft associated, GPI-anchored cell membrane glycoprotein. Misfolding of cellular PrPC into the pathogenic PrPSc results in Prion disease, an untreatable and fatal ne...
Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. In early 2016 we developed a pipe...
Fusion genes are hybrid genes formed by the fusion of two separate genes. Translocation, interstitial deletion and chromosomal inversions are some of the genetic events that can lead to the f...
Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades. Next-Generation Sequencing (NGS) technology r...
Vitamin D insufficiency and deficiency are prevalent worldwide, and pregnant women and infants are at highest risk for having deficiency and related consequences. Epidemiologic studies have s...
DATE: October 19, 2016
TIME: 9:00 AM PT, 12:00 PM ET, 6:00 PM CEST
Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
Induced pluripotent stem cells derived from patient cells have emerged as complementary tools to study human neurological disorders. Neurxstem Inc has generated human iPSC-derived synth...
Cell Sciences Innovation, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ USA
In vitro translational models play a critical role in the drug discovery process because t...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
Intra-tumor heterogeneity is a major obstacle to cancer treatment. Existing single-cell studies of intra-tumor heterogeneity have largely focused on DNA mutations; functional heterogeneity is...
Circulating Tumor Cells (CTCs) have been extensively explored as circulating biomarkers in various cancers. Due to their rarity, heterogeneity and stem cell-like properties, detecting and pro...
Real-time multiplex PCR assays are potentially the most rapid, most sensitive,and least expensive way to assess the abundance of mutant DNA fragments present in liquid biopsies; provided th...
Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
Tumor heterogeneity has been known for a while but quantifying heterogeneity is still a challenge. NGS is the method of choice in the analysis of tumor heterogeneity, however, there are...
PRESENTED BY:DATE: September 29, 2016TIME: 8:00AM PT, 11AM ETInterest in 3D cell culture has grown exponentially in recent years, partially due to 3D cultures hel...
ME/CFS is a debilitating disease with a controversial history and multiple names. The Institute of Medicine recently recommended renaming the disease “Systemic Exertion Intoleranc...
Our speaker, Wenjie Xu, Ph.D., will present his publication data demonstrating how nCounter® technology can advance your infectious disease research faster and more accurately with unprec...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and va...
In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
The study of human genetic neurodevelopmental disorders (NDDs) is complicated by the inaccessibility of the relevant tissue for study: it is extremely rare to obtain post-surgical brain sampl...
Over the last 15 years, human pluripotent stem cell (hPSC) technologies have progressed from academic curiosities into tools with the promise to underpin commerce, leading to real progress in...
PrPC is a conserved lipid-raft associated, GPI-anchored cell membrane glycoprotein. Misfolding of cellular PrPC into the pathogenic PrPSc results in Prion disease, an untreatable and fatal ne...
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