T-Cells: A type of white blood cell that plays an important role in the immune system. They are produced by the thymus gland and help the body fight off viruses, bacteria, and parasites. 
            
            
            
         
     
    
        
                    
                                    
                
         
                
                    
                                        
                        
                    
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        Alongside intense efforts to exploit T-cells as immunotherapies for cancer (e.g. checkpoint inhibitors, CAR-T, T-cell metabolism), researchers are increasingly considering other immune cell t...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        DATE: October 23, 2018TIME: 10:00am PDT, 1:00pm EDT Next-generation genomic sequencing is transforming what is known about pediatric cancer and how we treat patients. But eve...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    
    
            
     
                                     
 
                                    
                                                                    
                                    
                                        
    
    
    
        Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA.  Prior work has demonstrated that CD4 helper T c...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        There is considerable excitement surrounding the treatment potential of T cell immunotherapies. Amongst these, CAR-T cells have demonstrated impressive therapeutic efficacy in a subset of hem...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
         DATE: September 20 2018TIME: 09:00am PDT, 12:00pm EDT Harnessing the immune system has emerged as a powerful therapeutic strategy in oncology. However, the limited...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        To ensure the immune system’s balance between the recognition of non-self and the prevention of autoimmunity, the activity of immune cells needs to be strictly controlled. During the pr...