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    Genome Editing

    Genome editing: a group of technologies that give scientists the ability to alter an organism's DNA. Several approaches to genome editing have been developed.

    Webinars

    • OCT 03, 2018 | 1:30 PM
      Whole-Genome Identification of CRISPR Targets
      Whole-Genome Identification of CRISPR Targets
      Gene editing using CRISPR is a very promising technology, and it has already had a significant impact on a number of research fields. However, while CRISPR makes targeted modifications easier...
      Speaker: Dimitri Perrin, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      OCT 03, 2018 | 12:00 PM
      Using CRISPR and Stem Cells to Treat Genetic Disease
      Using CRISPR and Stem Cells to Treat Genetic Disease
      Decoding human genetic disease allows us to develop models of the pathology that can be directly tested with gene correction or targeted drug therapy.  Dominant negative mutations are pa...
      Speaker: Bruce Conklin, MD
      Presented at: CRISPR Virtual Event Series 2018
      1
      OCT 03, 2018 | 12:00 PM
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
      All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
      Speaker: Dipali Sashital, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
      OCT 03, 2018 | 10:30 AM
      Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
      Integrating Novel Advances in Gene Delivery and Genome Engineering...
      There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
      Speaker: David Schaffer, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      OCT 03, 2018 | 9:00 AM
      Design, Edit, Analyze and Maximize Your CRISPR-Cas9 Editing Efficiency
      Design, Edit, Analyze and Maximize Your CRISPR-Cas9 Editing Efficiency
      Learn how to optimize CRISPR-Cas9 editing efficiencies in cell lines and primary cell types using modified synthetic sgRNA. Includes tips for achieving maximum knockout and knock-in efficienc...
      Speaker: Kevin Holden, PhD
      Presented at: CRISPR Virtual Event Series 2018
      Sponsored By: Synthego
      2
      OCT 03, 2018 | 9:00 AM
      CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs in CRISPR-Cas9 Genome-Editing Systems
      CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs...
      The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
      Speaker: Lihua Julie Zhu, PhD
      Presented at: CRISPR Virtual Event Series 2018
      3
      OCT 03, 2018 | 7:30 AM
      Keynote Presentation: Measurements and Standards to Support Confidence in Genome Editing
      Keynote Presentation: Measurements and Standards to Support Confidence...
      The National Institute of Standards and Technology (NIST), is the measurement institute of the U.S., supplying unbiased expertise in measurements and standards to support growth in all sector...
      Speaker: Samantha Maragh, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      OCT 03, 2018 | 6:00 AM
      Identification of Pre-existing Adaptive Immune Responses to Cas9 in Humans
      Identification of Pre-existing Adaptive Immune Responses to Cas9...
      The CRISPR-Cas9 system has proven to be a powerful tool for genome editing allowing for the precise modification of specific DNA sequences within a cell. Many efforts are currently underway t...
      Speaker: Carsten Charlesworth, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      SEP 26, 2018 | 9:00 AM
      How to Utilize the Power of CRISPR in Your Research
      How to Utilize the Power of CRISPR in Your Research
      CRISPR has revolutionized how we do science in a similar way PCR changed the face of molecular biology. Learn how to take advantage of this phenomenal technology in the easiest way with Synth...
      Speaker: Ania Wronski, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      Sponsored By: Synthego
      1
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      AUG 09, 2018 | 8:00 AM
      Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
      Exon-level array: Bridging the gap between chromosomal microarray...
      DATE:  August 9, 2018TIME:  8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
      Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      9
      JUL 19, 2018 | 9:00 AM
      Investigating the role of microRNAs in pancreatic cancer progression
      Investigating the role of microRNAs in pancreatic cancer progression
      DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
      Speaker: Silvia Ottaviani, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 5
      MAY 22, 2018 | 8:00 AM
      Drug development with nuclear receptor knockout and humanized rat models
      Drug development with nuclear receptor knockout and humanized...
      DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
      Speaker: Kevin Forbes, PhD , Andrew Brown, MS
      Sponsored By: Horizon Discovery
      5
      MAY 10, 2018 | 1:30 PM
      C.E. CREDITS
      Population Genomic Screening: The Alabama Genomic Health Initiative
      Population Genomic Screening: The Alabama Genomic Health Initiative
      As the costs of genomic analysis decline it becomes possible to offer widescale population genomic analysis to screen for genetic disorders.  The Alabama Genomic Health Initiative was es...
      Speaker: Bruce R. Korf, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 10, 2018 | 6:00 AM
      C.E. CREDITS
      Multiplexed Precision Genome Editing with Trackable Genome-Integrated Barcodes in Yeast
      Multiplexed Precision Genome Editing with Trackable Genome-Integrated...
      Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. In this pr...
      Speaker: Kevin Roy, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 09, 2018 | 1:30 PM
      Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
      Next-Generation Sequencing to Understand the Function of miRNAs...
      There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
      Speaker: Ulrich Broeckel, MD , Amy Turner, BS
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      MAR 27, 2018 | 9:00 AM
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
      Speaker: Amanda Haas
      Sponsored By: Horizon Discovery
      23 15
      MAR 14, 2018 | 10:30 AM
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
      CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
      Speaker: Jeremy Lehmann
      Presented at: Neuroscience Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      1
      MAR 01, 2018 | 12:00 AM
      Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
      Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
      The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
      Speaker: William Hendriks
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      FEB 22, 2018 | 9:00 AM
      Investigating colorectal cancer using epithelial organoid cultures
      Investigating colorectal cancer using epithelial organoid cultures
      DATE: February 22, 2018TIME: 09:00am PST, 12:00pm EST, 06:00pm CEST(Europe)Colorectal cancer (CRC) develops during a multi-step process from small lesions of the intestinal epithelium....
      Speaker: Kai Kretzschmar, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 3
      JAN 30, 2018 | 9:00 AM
      WEBINAR: Metagenomics and base modifications from long, short, and linked-reads
      WEBINAR: Metagenomics and base modifications from long, short,...
      DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
      Speaker: Christopher Mason, PhD , Shuiquan Tang, PhD
      Sponsored By: Zymo Research
      6 1
      JAN 01, 2018 | 10:00 AM
      Disease modelling with human pluripotent stem cells: general principles and specific applications to obesity
      Disease modelling with human pluripotent stem cells: general principles...
      The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
      Speaker: Florian Merkle
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      DEC 06, 2017 | 8:00 AM
      WEBINAR:  #5: A Complete Workflow for Human Cell Line Authentication
      WEBINAR: #5: A Complete Workflow for Human Cell Line Authentication
      DATE: November 16, 2017TIME: 7:00am PST, 10:00 am EST, 3:00pm CETThis is the fifth topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’Th...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      5 2
      DEC 01, 2017 | 12:00 AM
      Beyond Automated iPSC reprogramming: applications for a fully automated cell culture system for pluripotent stem cell research
      Beyond Automated iPSC reprogramming: applications for a fully...
      The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
      Speaker: Daniel Paull
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
    OCT 03, 2018 | 1:30 PM
    Whole-Genome Identification of CRISPR Targets
    Whole-Genome Identification of CRISPR Targets
    Gene editing using CRISPR is a very promising technology, and it has already had a significant impact on a number of research fields. However, while CRISPR makes targeted modifications easier...
    Speaker: Dimitri Perrin, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    OCT 03, 2018 | 12:00 PM
    Using CRISPR and Stem Cells to Treat Genetic Disease
    Using CRISPR and Stem Cells to Treat Genetic Disease
    Decoding human genetic disease allows us to develop models of the pathology that can be directly tested with gene correction or targeted drug therapy.  Dominant negative mutations are pa...
    Speaker: Bruce Conklin, MD
    Presented at: CRISPR Virtual Event Series 2018
    1
    OCT 03, 2018 | 12:00 PM
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    Mechanisms of CRISPR-Cas Systems: From Adaptive Immunity to Biotechnology
    All forms of life require immune systems to stave off infection from viruses and other pathogens. In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) a...
    Speaker: Dipali Sashital, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
    OCT 03, 2018 | 10:30 AM
    Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
    Integrating Novel Advances in Gene Delivery and Genome Engineering...
    There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
    Speaker: David Schaffer, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    OCT 03, 2018 | 9:00 AM
    Design, Edit, Analyze and Maximize Your CRISPR-Cas9 Editing Efficiency
    Design, Edit, Analyze and Maximize Your CRISPR-Cas9 Editing Efficiency
    Learn how to optimize CRISPR-Cas9 editing efficiencies in cell lines and primary cell types using modified synthetic sgRNA. Includes tips for achieving maximum knockout and knock-in efficienc...
    Speaker: Kevin Holden, PhD
    Presented at: CRISPR Virtual Event Series 2018
    Sponsored By: Synthego
    2
     
     
  • OCT 03, 2018 | 9:00 AM
    CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs in CRISPR-Cas9 Genome-Editing Systems
    CRISPRseek and GUIDEseq for Design of Target-Specific Guide RNAs...
    The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
    Speaker: Lihua Julie Zhu, PhD
    Presented at: CRISPR Virtual Event Series 2018
    3
    OCT 03, 2018 | 7:30 AM
    Keynote Presentation: Measurements and Standards to Support Confidence in Genome Editing
    Keynote Presentation: Measurements and Standards to Support Confidence...
    The National Institute of Standards and Technology (NIST), is the measurement institute of the U.S., supplying unbiased expertise in measurements and standards to support growth in all sector...
    Speaker: Samantha Maragh, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    OCT 03, 2018 | 6:00 AM
    Identification of Pre-existing Adaptive Immune Responses to Cas9 in Humans
    Identification of Pre-existing Adaptive Immune Responses to Cas9...
    The CRISPR-Cas9 system has proven to be a powerful tool for genome editing allowing for the precise modification of specific DNA sequences within a cell. Many efforts are currently underway t...
    Speaker: Carsten Charlesworth, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    SEP 26, 2018 | 9:00 AM
    How to Utilize the Power of CRISPR in Your Research
    How to Utilize the Power of CRISPR in Your Research
    CRISPR has revolutionized how we do science in a similar way PCR changed the face of molecular biology. Learn how to take advantage of this phenomenal technology in the easiest way with Synth...
    Speaker: Ania Wronski, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    Sponsored By: Synthego
    1
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
     
     
  • AUG 09, 2018 | 8:00 AM
    Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
    Exon-level array: Bridging the gap between chromosomal microarray...
    DATE:  August 9, 2018TIME:  8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
    Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    9
    JUL 19, 2018 | 9:00 AM
    Investigating the role of microRNAs in pancreatic cancer progression
    Investigating the role of microRNAs in pancreatic cancer progression
    DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
    Speaker: Silvia Ottaviani, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 5
    MAY 22, 2018 | 8:00 AM
    Drug development with nuclear receptor knockout and humanized rat models
    Drug development with nuclear receptor knockout and humanized...
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    Speaker: Kevin Forbes, PhD , Andrew Brown, MS
    Sponsored By: Horizon Discovery
    5
    MAY 10, 2018 | 1:30 PM
    C.E. CREDITS
    Population Genomic Screening: The Alabama Genomic Health Initiative
    Population Genomic Screening: The Alabama Genomic Health Initiative
    As the costs of genomic analysis decline it becomes possible to offer widescale population genomic analysis to screen for genetic disorders.  The Alabama Genomic Health Initiative was es...
    Speaker: Bruce R. Korf, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    MAY 10, 2018 | 6:00 AM
    C.E. CREDITS
    Multiplexed Precision Genome Editing with Trackable Genome-Integrated Barcodes in Yeast
    Multiplexed Precision Genome Editing with Trackable Genome-Integrated...
    Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. In this pr...
    Speaker: Kevin Roy, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
     
     
  • MAY 09, 2018 | 1:30 PM
    Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
    Next-Generation Sequencing to Understand the Function of miRNAs...
    There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
    Speaker: Ulrich Broeckel, MD , Amy Turner, BS
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    MAR 27, 2018 | 9:00 AM
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
    Speaker: Amanda Haas
    Sponsored By: Horizon Discovery
    23 15
    MAR 14, 2018 | 10:30 AM
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
    CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
    Speaker: Jeremy Lehmann
    Presented at: Neuroscience Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    1
    MAR 01, 2018 | 12:00 AM
    Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
    Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
    The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
    Speaker: William Hendriks
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    FEB 22, 2018 | 9:00 AM
    Investigating colorectal cancer using epithelial organoid cultures
    Investigating colorectal cancer using epithelial organoid cultures
    DATE: February 22, 2018TIME: 09:00am PST, 12:00pm EST, 06:00pm CEST(Europe)Colorectal cancer (CRC) develops during a multi-step process from small lesions of the intestinal epithelium....
    Speaker: Kai Kretzschmar, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 3
     
     
  • JAN 30, 2018 | 9:00 AM
    WEBINAR: Metagenomics and base modifications from long, short, and linked-reads
    WEBINAR: Metagenomics and base modifications from long, short,...
    DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
    Speaker: Christopher Mason, PhD , Shuiquan Tang, PhD
    Sponsored By: Zymo Research
    6 1
    JAN 01, 2018 | 10:00 AM
    Disease modelling with human pluripotent stem cells: general principles and specific applications to obesity
    Disease modelling with human pluripotent stem cells: general principles...
    The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
    Speaker: Florian Merkle
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    DEC 06, 2017 | 8:00 AM
    WEBINAR:  #5: A Complete Workflow for Human Cell Line Authentication
    WEBINAR: #5: A Complete Workflow for Human Cell Line Authentication
    DATE: November 16, 2017TIME: 7:00am PST, 10:00 am EST, 3:00pm CETThis is the fifth topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’Th...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    5 2
    DEC 01, 2017 | 12:00 AM
    Beyond Automated iPSC reprogramming: applications for a fully automated cell culture system for pluripotent stem cell research
    Beyond Automated iPSC reprogramming: applications for a fully...
    The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
    Speaker: Daniel Paull
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
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