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    Cell Death

    Cell death terminates normal cellular functions, including respiration, metabolism, growth and proliferation. Cell death can be non-programmed, for example as the result of accidental injury or trauma, or programmed. Types of programmed cell death include anoikis, apoptosis, autophagy, necrosis, necroptosis and pyroptosis.

    Webinars

    • OCT 11, 2018 | 12:00 PM
      Lung Cancer Evolution and Immune Escape
      Lung Cancer Evolution and Immune Escape
      Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
      Speaker: Nicholas McGranahan, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      JUN 27, 2018 | 8:00 AM
      Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize success
      Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize...
      DATE: June 27, 2018TIME: 08:00AM PDT CRISPR-Cas9 is a very versatile tool to discover more about your pathway or gene of interest. Its simplicity has led to an explosion in a...
      Speaker: Laura Carleton, PhD
      Sponsored By: Horizon Discovery
      13 1
      MAY 10, 2018 | 9:00 AM
      Multi-Omics Approach for Discovering Anti-Folate Drug Resistance Mechanisms in Triple-Negative Breast Cancer: Working Toward the Goal of Personalized Medicine
      Multi-Omics Approach for Discovering Anti-Folate Drug Resistance...
      Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments.  Metabolic reprograming is now recognized as a fundam...
      Speaker: Steven Gross, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: Agilent
      1
      MAR 29, 2018 | 12:00 PM
      Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
      Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
      It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
      Speaker: Judy Mikovits, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      MAR 15, 2018 | 10:30 AM
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
      The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
      Speaker: Jill Weimer, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      FEB 21, 2018 | 6:00 AM
      Using HDAC Inhibitors to Improve Cancer Immunotherapy
      Using HDAC Inhibitors to Improve Cancer Immunotherapy
      We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
      Speaker: Alejandro Villagra, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      NOV 29, 2017 | 10:00 AM
      WEBINAR: RAS Oncoproteins: Therapeutic Vulnerabilities
      WEBINAR: RAS Oncoproteins: Therapeutic Vulnerabilities
      DATE: November 29, 2017TIME: 10:00 AM PSTThe three human RAS genes (HRAS, KRAS and NRAS) encode four highly related RAS small GTPases (HRAS, KRAS4A, KRAS4B and NRAS). RAS proteins funct...
      Speaker: Adrienne Cox, PhD
      Sponsored By: ACD - A Bio-Techne Brand
      7 2
      NOV 08, 2017 | 12:00 PM
      Combined immunohistochemistry and RNA in situ hybridization to elucidate tumor molecular heterogeneity in prostate cancer
      Combined immunohistochemistry and RNA in situ hybridization to...
      Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
      Speaker: Nallasivam Palanisamy, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      Sponsored By: Advanced Cell Diagnostics
      3
      OCT 11, 2017 | 9:00 AM
      New insights into the role of actin cytoskeleton and autophagy at the immune synapse
      New insights into the role of actin cytoskeleton and autophagy...
      Natural killer cells (NKs) are lymphocytes of the innate immune system that target and kill cancer cells through the secretion of lytic granules containing granzyme B and perforin. This proce...
      Speaker: Antoun Al Absi
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      Sponsored By: MilliporeSigma
      1
      OCT 11, 2017 | 6:00 AM
      Cancer Chemotherapy and the tools needed to Advance Treatment in a Diverse Racial Population
      Cancer Chemotherapy and the tools needed to Advance Treatment...
      Colorectal  cancer  (CRC)  is  the  third  most  commonly  diagnosed  cancer  and  is  the  third leading  cause of  ...
      Speaker: Jennie Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      OCT 05, 2017 | 6:00 AM
      Battle the heat in your lab - facing distorted results caused by temperature fluctuations
      Battle the heat in your lab - facing distorted results caused...
      DATE: October 5th, 2017TIME:  6:00am PT, 9:00am ETIn this webinar you will learn: that temperature variations in your lab and detection instrument will distort your results...
      Speaker: Gediminas Vidugiris, PhD , Katrin Flatscher, PhD
      Sponsored By: Tecan
      6
      SEP 28, 2017 | 10:00 AM
      WEBINAR: Development of anti-cancer gene therapies through understanding of cytokine-induced programmed cell death
      WEBINAR: Development of anti-cancer gene therapies through understanding...
      DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
      Speaker: Leah Persaud
      Sponsored By: Thermo Fisher Scientific/Gibco
      11 2
      SEP 13, 2017 | 1:30 PM
      The escalating challenges of antimicrobial resistance and the efforts to conquer these threats
      The escalating challenges of antimicrobial resistance and the...
      The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
      Speaker: Glenn Tillotson, PhD, FIDSA, FCCP
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      3 1
      SEP 07, 2017 | 9:00 AM
      WEBINAR: Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
      WEBINAR: Glycosylation and stabilization of programmed death ligand-1...
      DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
      Speaker: Chia-Wei Li, PhD
      Sponsored By: Essen BioScience
      5
    OCT 11, 2018 | 12:00 PM
    Lung Cancer Evolution and Immune Escape
    Lung Cancer Evolution and Immune Escape
    Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
    Speaker: Nicholas McGranahan, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
    OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
     
     
  • OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    JUN 27, 2018 | 8:00 AM
    Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize success
    Cell line engineering with CRISPR-Cas9 - Tips and tricks to maximize...
    DATE: June 27, 2018TIME: 08:00AM PDT CRISPR-Cas9 is a very versatile tool to discover more about your pathway or gene of interest. Its simplicity has led to an explosion in a...
    Speaker: Laura Carleton, PhD
    Sponsored By: Horizon Discovery
    13 1
    MAY 10, 2018 | 9:00 AM
    Multi-Omics Approach for Discovering Anti-Folate Drug Resistance Mechanisms in Triple-Negative Breast Cancer: Working Toward the Goal of Personalized Medicine
    Multi-Omics Approach for Discovering Anti-Folate Drug Resistance...
    Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments.  Metabolic reprograming is now recognized as a fundam...
    Speaker: Steven Gross, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: Agilent
    1
    MAR 29, 2018 | 12:00 PM
    Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
    Cannabis as Immunonotherapy for 21st Century Acquired Immune Deficiencies
    It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
    Speaker: Judy Mikovits, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    MAR 15, 2018 | 10:30 AM
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
    The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
    Speaker: Jill Weimer, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
     
     
  • FEB 21, 2018 | 6:00 AM
    Using HDAC Inhibitors to Improve Cancer Immunotherapy
    Using HDAC Inhibitors to Improve Cancer Immunotherapy
    We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
    Speaker: Alejandro Villagra, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    NOV 29, 2017 | 10:00 AM
    WEBINAR: RAS Oncoproteins: Therapeutic Vulnerabilities
    WEBINAR: RAS Oncoproteins: Therapeutic Vulnerabilities
    DATE: November 29, 2017TIME: 10:00 AM PSTThe three human RAS genes (HRAS, KRAS and NRAS) encode four highly related RAS small GTPases (HRAS, KRAS4A, KRAS4B and NRAS). RAS proteins funct...
    Speaker: Adrienne Cox, PhD
    Sponsored By: ACD - A Bio-Techne Brand
    7 2
    NOV 08, 2017 | 12:00 PM
    Combined immunohistochemistry and RNA in situ hybridization to elucidate tumor molecular heterogeneity in prostate cancer
    Combined immunohistochemistry and RNA in situ hybridization to...
    Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
    Speaker: Nallasivam Palanisamy, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    Sponsored By: Advanced Cell Diagnostics
    3
    OCT 11, 2017 | 9:00 AM
    New insights into the role of actin cytoskeleton and autophagy at the immune synapse
    New insights into the role of actin cytoskeleton and autophagy...
    Natural killer cells (NKs) are lymphocytes of the innate immune system that target and kill cancer cells through the secretion of lytic granules containing granzyme B and perforin. This proce...
    Speaker: Antoun Al Absi
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    Sponsored By: MilliporeSigma
    1
    OCT 11, 2017 | 6:00 AM
    Cancer Chemotherapy and the tools needed to Advance Treatment in a Diverse Racial Population
    Cancer Chemotherapy and the tools needed to Advance Treatment...
    Colorectal  cancer  (CRC)  is  the  third  most  commonly  diagnosed  cancer  and  is  the  third leading  cause of  ...
    Speaker: Jennie Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
     
     
  • OCT 05, 2017 | 6:00 AM
    Battle the heat in your lab - facing distorted results caused by temperature fluctuations
    Battle the heat in your lab - facing distorted results caused...
    DATE: October 5th, 2017TIME:  6:00am PT, 9:00am ETIn this webinar you will learn: that temperature variations in your lab and detection instrument will distort your results...
    Speaker: Gediminas Vidugiris, PhD , Katrin Flatscher, PhD
    Sponsored By: Tecan
    6
    SEP 28, 2017 | 10:00 AM
    WEBINAR: Development of anti-cancer gene therapies through understanding of cytokine-induced programmed cell death
    WEBINAR: Development of anti-cancer gene therapies through understanding...
    DATE: September 28, 2017TIME: 10:00am PDT, 1:00pm EDT The use of gene therapy is well studied due to its potential to treat cancer, the second leading cause of death worldwide....
    Speaker: Leah Persaud
    Sponsored By: Thermo Fisher Scientific/Gibco
    11 2
    SEP 13, 2017 | 1:30 PM
    The escalating challenges of antimicrobial resistance and the efforts to conquer these threats
    The escalating challenges of antimicrobial resistance and the...
    The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
    Speaker: Glenn Tillotson, PhD, FIDSA, FCCP
    Presented at: Microbiology & Immunology Virtual Event Series 2017
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    SEP 07, 2017 | 9:00 AM
    WEBINAR: Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
    WEBINAR: Glycosylation and stabilization of programmed death ligand-1...
    DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
    Speaker: Chia-Wei Li, PhD
    Sponsored By: Essen BioScience
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