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    In Vivo

    In Vivo: are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

    Webinars

    • MAR 28, 2018 | 12:00 PM
      Economies of Scale in Cannabis: Moving from lab-scale CO2 Extraction (SFE) to production-scale
      Economies of Scale in Cannabis: Moving from lab-scale CO2 Extraction...
      As with all new unique recreational or nutritional natural products, the cannabis supply chain will change from state-to-state and become more uniform and efficient over time.  From deca...
      Speaker: Lalit Chordia, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      MAR 28, 2018 | 10:30 AM
      Factors That Influence Label Accuracy - Who's to Blame?
      Factors That Influence Label Accuracy - Who's to Blame?
      DATE: March 28, 2018TIME: 10:30AM PDTAs consumers in modern society, we have become accustomed to the purchase of foods and drugs that are safe and accurately labeled. This is a result...
      Speaker: Catharine Layton
      Presented at: Cannabis Sciences Virtual Event Series 2018
      4
      MAR 28, 2018 | 10:30 AM
      Panel Discussion: Medical Cannabis in Pediatrics
      Panel Discussion: Medical Cannabis in Pediatrics
      In this panel discussion, parents of children using cannabis discuss their experience Herah Osborne: A mother’s story about her journey with her twins having Fragile X syndrome an...
      Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP , Sebastien Cotte , Janie Maedler , Herah Osborne
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      MAR 28, 2018 | 9:00 AM
      Sampling for Cannabis Testing
      Sampling for Cannabis Testing
      Compliance testing is the key to getting your cannabis products to market.  But also ensuring your product safety and label accuracy require not only good laboratory analyses, but consis...
      Speaker: Shawn Kassner
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      MAR 28, 2018 | 9:00 AM
      Drug Development and Approval in the U.S.: Regulatory Challenges and Opportunities for Cannabis Therapies
      Drug Development and Approval in the U.S.: Regulatory Challenges...
      Although more than half of U.S. states have legalized the use of medical marijuana, the U.S. Food and Drug Administration (FDA) has not yet recognized or approved the cannabis plant for thera...
      Speaker: Emily Leongini
      Presented at: Cannabis Sciences Virtual Event Series 2018
      1
      MAR 28, 2018 | 9:00 AM
      Controlling Terpenes and Cannabinoids in Flower and Extract
      Controlling Terpenes and Cannabinoids in Flower and Extract
      Cannabis and its products are referred to in the USA as Medical Marijuana. The traditional approach tomedical research of a single compound for a single target does not work for cannabis, a...
      Speaker: Markus Roggen, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      MAR 28, 2018 | 7:30 AM
      Keynote Presentation: Treating with Cannabis
      Keynote Presentation: Treating with Cannabis
      Cannabis use, both recreational and as medicine is proliferating worldwide. It's reasonable to ask why people are using cannabis and who are appropriate candidates for cannabis therapy. T...
      Speaker: Jeff Hergenrather, MD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      4
      MAR 28, 2018 | 6:00 AM
      Cannabis Impact on Pain and Opiate Use - A Clinician's Perspective
      Cannabis Impact on Pain and Opiate Use - A Clinician's Perspective
      Pain management is the most commonly reported reason for seeking medical cannabis, which is associated with lower opioid use, fewer medication side effects and better quality of life in patie...
      Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP
      Presented at: Cannabis Sciences Virtual Event Series 2018
      5
      MAR 28, 2018 | 6:00 AM
      Extraction and the Labeling of Cannabis Products
      Extraction and the Labeling of Cannabis Products
      There is growing consumer and patient demand for products containing cannabidiol (CBD) and other constituents of the cannabis plant, due to their purported medicinal benefits for a myriad of...
      Speaker: Jahan Marcu, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      6
      MAR 22, 2018 | 9:00 AM
      Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
      Differentiation sensitizes stem-like glioblastoma tumor-initiating...
      DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
      Speaker: Jasmine Hughes
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 4
      MAR 15, 2018 | 10:30 AM
      An Emerging Role of DNA Damage-Repair in Huntington's Disease
      An Emerging Role of DNA Damage-Repair in Huntington's Disease
      Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
      Speaker: Animesh Ray, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
      MAR 14, 2018 | 12:00 PM
      Decoding How Clathrin is Transported to Distal Synapses Along Axons
      Decoding How Clathrin is Transported to Distal Synapses Along...
      Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
      Speaker: Archan Ganguly, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      2
      MAR 14, 2018 | 10:30 AM
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
      CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
      Speaker: Jeremy Lehmann
      Presented at: Neuroscience Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      1
      MAR 14, 2018 | 6:00 AM
      Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics and Functional Magnetic Resonance Imaging
      Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics...
      Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      4 1
      FEB 21, 2018 | 12:00 PM
      Allosteric Modulation of Metabotropic Glutamate Receptors for the Treatment of Neurodevelopmental Disorders
      Allosteric Modulation of Metabotropic Glutamate Receptors for...
      Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
      Speaker: Colleen Niswender, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      FEB 21, 2018 | 9:00 AM
      Application of a Novel Cell Proliferation Biomarker in Cancer Drug Development: Immunoassay of Thymidine Kinase 1 in In-Vitro and In-Vivo Studies of Hematological and Solid Malignancies
      Application of a Novel Cell Proliferation Biomarker in Cancer...
      There are many tumor biomarkers but, they mostly reflect tumor mass or past growth, when what is more important is to obtain an indication of future growth and therapy response.Proliferat...
      Speaker: Martin Shaw
      Presented at: Drug Discovery Virtual Event Series 2018
      3
      FEB 08, 2018 | 1:30 PM
      Applications of Preclinical Translational Imaging Technologies for Improved Modeling and Decision Making
      Applications of Preclinical Translational Imaging Technologies...
      Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
      Speaker: Paul Makidon, DVM, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      3
      FEB 08, 2018 | 7:30 AM
      Modernization of Animal Studies
      Modernization of Animal Studies
      There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
      Speaker: Natalie Bratcher , Sean Maguire, VMD, MS, DACLAM , Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      2
      FEB 07, 2018 | 12:00 PM
      Refinement of a Model of Repeated Cerebrospinal Fluid Collection in Conscious Rats
      Refinement of a Model of Repeated Cerebrospinal Fluid Collection...
      Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
      Speaker: Eva Maria Amen, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      2
      JAN 31, 2018 | 8:00 AM
      High Content Screening-Based Phenotypic Analysis Of Organotypic 3D Bronchial Tissues
      High Content Screening-Based Phenotypic Analysis Of Organotypic...
      One of the goals of the “3Rs principle” is to replace in vivo testing methodologies with in vitro procedures on human cells, followed by computational systems biology modelling to...
      Speaker: Diego Marescotti, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      9 1
      JAN 25, 2018 | 10:00 AM
      WEBINAR:  Engineered Viruses as Precision Cancer Therapeutics
      WEBINAR: Engineered Viruses as Precision Cancer Therapeutics
      DATE: January 25, 2018TIME: 10:00am PST, 1:00pm EST, 6:00pm GMTOncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehi...
      Speaker: Alexander Baker, MSci (Hons), 1st Class
      Sponsored By: Thermo Fisher Scientific/Gibco
      12
      DEC 05, 2017 | 6:00 AM
      WEBINAR: Androgen signaling in advanced prostate cancer models using noninvasive hyper polarized MRI and mass spectrometry
      WEBINAR: Androgen signaling in advanced prostate cancer models...
      DATE: December 5th, 2017TIME:  6:00AM PTAndrogen receptor (AR) signaling remains a driver in the lethal phenotype of prostate cancer, castrate resistant prostate cancer (CRPC). Nov...
      Speaker: Mark Titus, PhD
      Sponsored By: Agilent
      4
      NOV 16, 2017 | 9:00 AM
      WEBINAR: Breaking Bad with 3D: The development of high throughput screening platforms to interrogate physiologically relevant models
      WEBINAR: Breaking Bad with 3D: The development of high throughput...
      DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
      Speaker: Madhu Nag, PhD
      Sponsored By: Revvity
      4
      NOV 14, 2017 | 10:00 AM
      WEBINAR:  Cancer Cells Send Signals Boosting Survival and Drug Resistance in Other Cancer Cells
      WEBINAR: Cancer Cells Send Signals Boosting Survival and Drug...
      DATE: November 14, 2017TIME: 10:00am PST, 1:00pm ESTSuccessful tumor outgrowth requires the coordination of a variety of cell intrinsic and cell extrinsic signaling events. These events...
      Speaker: Jeffrey Rodvold, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco, Thermo Fisher Scientific/Gibco
      5 5
    MAR 28, 2018 | 12:00 PM
    Economies of Scale in Cannabis: Moving from lab-scale CO2 Extraction (SFE) to production-scale
    Economies of Scale in Cannabis: Moving from lab-scale CO2 Extraction...
    As with all new unique recreational or nutritional natural products, the cannabis supply chain will change from state-to-state and become more uniform and efficient over time.  From deca...
    Speaker: Lalit Chordia, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    MAR 28, 2018 | 10:30 AM
    Factors That Influence Label Accuracy - Who's to Blame?
    Factors That Influence Label Accuracy - Who's to Blame?
    DATE: March 28, 2018TIME: 10:30AM PDTAs consumers in modern society, we have become accustomed to the purchase of foods and drugs that are safe and accurately labeled. This is a result...
    Speaker: Catharine Layton
    Presented at: Cannabis Sciences Virtual Event Series 2018
    4
    MAR 28, 2018 | 10:30 AM
    Panel Discussion: Medical Cannabis in Pediatrics
    Panel Discussion: Medical Cannabis in Pediatrics
    In this panel discussion, parents of children using cannabis discuss their experience Herah Osborne: A mother’s story about her journey with her twins having Fragile X syndrome an...
    Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP , Sebastien Cotte , Janie Maedler , Herah Osborne
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    MAR 28, 2018 | 9:00 AM
    Sampling for Cannabis Testing
    Sampling for Cannabis Testing
    Compliance testing is the key to getting your cannabis products to market.  But also ensuring your product safety and label accuracy require not only good laboratory analyses, but consis...
    Speaker: Shawn Kassner
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    MAR 28, 2018 | 9:00 AM
    Drug Development and Approval in the U.S.: Regulatory Challenges and Opportunities for Cannabis Therapies
    Drug Development and Approval in the U.S.: Regulatory Challenges...
    Although more than half of U.S. states have legalized the use of medical marijuana, the U.S. Food and Drug Administration (FDA) has not yet recognized or approved the cannabis plant for thera...
    Speaker: Emily Leongini
    Presented at: Cannabis Sciences Virtual Event Series 2018
    1
     
     
  • MAR 28, 2018 | 9:00 AM
    Controlling Terpenes and Cannabinoids in Flower and Extract
    Controlling Terpenes and Cannabinoids in Flower and Extract
    Cannabis and its products are referred to in the USA as Medical Marijuana. The traditional approach tomedical research of a single compound for a single target does not work for cannabis, a...
    Speaker: Markus Roggen, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    MAR 28, 2018 | 7:30 AM
    Keynote Presentation: Treating with Cannabis
    Keynote Presentation: Treating with Cannabis
    Cannabis use, both recreational and as medicine is proliferating worldwide. It's reasonable to ask why people are using cannabis and who are appropriate candidates for cannabis therapy. T...
    Speaker: Jeff Hergenrather, MD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    4
    MAR 28, 2018 | 6:00 AM
    Cannabis Impact on Pain and Opiate Use - A Clinician's Perspective
    Cannabis Impact on Pain and Opiate Use - A Clinician's Perspective
    Pain management is the most commonly reported reason for seeking medical cannabis, which is associated with lower opioid use, fewer medication side effects and better quality of life in patie...
    Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP
    Presented at: Cannabis Sciences Virtual Event Series 2018
    5
    MAR 28, 2018 | 6:00 AM
    Extraction and the Labeling of Cannabis Products
    Extraction and the Labeling of Cannabis Products
    There is growing consumer and patient demand for products containing cannabidiol (CBD) and other constituents of the cannabis plant, due to their purported medicinal benefits for a myriad of...
    Speaker: Jahan Marcu, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    6
    MAR 22, 2018 | 9:00 AM
    Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
    Differentiation sensitizes stem-like glioblastoma tumor-initiating...
    DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
    Speaker: Jasmine Hughes
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 4
     
     
  • MAR 15, 2018 | 10:30 AM
    An Emerging Role of DNA Damage-Repair in Huntington's Disease
    An Emerging Role of DNA Damage-Repair in Huntington's Disease
    Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
    Speaker: Animesh Ray, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
    MAR 14, 2018 | 12:00 PM
    Decoding How Clathrin is Transported to Distal Synapses Along Axons
    Decoding How Clathrin is Transported to Distal Synapses Along...
    Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
    Speaker: Archan Ganguly, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    2
    MAR 14, 2018 | 10:30 AM
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
    CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
    Speaker: Jeremy Lehmann
    Presented at: Neuroscience Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    1
    MAR 14, 2018 | 6:00 AM
    Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics and Functional Magnetic Resonance Imaging
    Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics...
    Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    4 1
    FEB 21, 2018 | 12:00 PM
    Allosteric Modulation of Metabotropic Glutamate Receptors for the Treatment of Neurodevelopmental Disorders
    Allosteric Modulation of Metabotropic Glutamate Receptors for...
    Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
    Speaker: Colleen Niswender, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
     
     
  • FEB 21, 2018 | 9:00 AM
    Application of a Novel Cell Proliferation Biomarker in Cancer Drug Development: Immunoassay of Thymidine Kinase 1 in In-Vitro and In-Vivo Studies of Hematological and Solid Malignancies
    Application of a Novel Cell Proliferation Biomarker in Cancer...
    There are many tumor biomarkers but, they mostly reflect tumor mass or past growth, when what is more important is to obtain an indication of future growth and therapy response.Proliferat...
    Speaker: Martin Shaw
    Presented at: Drug Discovery Virtual Event Series 2018
    3
    FEB 08, 2018 | 1:30 PM
    Applications of Preclinical Translational Imaging Technologies for Improved Modeling and Decision Making
    Applications of Preclinical Translational Imaging Technologies...
    Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
    Speaker: Paul Makidon, DVM, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
    3
    FEB 08, 2018 | 7:30 AM
    Modernization of Animal Studies
    Modernization of Animal Studies
    There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
    Speaker: Natalie Bratcher , Sean Maguire, VMD, MS, DACLAM , Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
    2
    FEB 07, 2018 | 12:00 PM
    Refinement of a Model of Repeated Cerebrospinal Fluid Collection in Conscious Rats
    Refinement of a Model of Repeated Cerebrospinal Fluid Collection...
    Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
    Speaker: Eva Maria Amen, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
    2
    JAN 31, 2018 | 8:00 AM
    High Content Screening-Based Phenotypic Analysis Of Organotypic 3D Bronchial Tissues
    High Content Screening-Based Phenotypic Analysis Of Organotypic...
    One of the goals of the “3Rs principle” is to replace in vivo testing methodologies with in vitro procedures on human cells, followed by computational systems biology modelling to...
    Speaker: Diego Marescotti, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    9 1
     
     
  • JAN 25, 2018 | 10:00 AM
    WEBINAR:  Engineered Viruses as Precision Cancer Therapeutics
    WEBINAR: Engineered Viruses as Precision Cancer Therapeutics
    DATE: January 25, 2018TIME: 10:00am PST, 1:00pm EST, 6:00pm GMTOncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehi...
    Speaker: Alexander Baker, MSci (Hons), 1st Class
    Sponsored By: Thermo Fisher Scientific/Gibco
    12
    DEC 05, 2017 | 6:00 AM
    WEBINAR: Androgen signaling in advanced prostate cancer models using noninvasive hyper polarized MRI and mass spectrometry
    WEBINAR: Androgen signaling in advanced prostate cancer models...
    DATE: December 5th, 2017TIME:  6:00AM PTAndrogen receptor (AR) signaling remains a driver in the lethal phenotype of prostate cancer, castrate resistant prostate cancer (CRPC). Nov...
    Speaker: Mark Titus, PhD
    Sponsored By: Agilent
    4
    NOV 16, 2017 | 9:00 AM
    WEBINAR: Breaking Bad with 3D: The development of high throughput screening platforms to interrogate physiologically relevant models
    WEBINAR: Breaking Bad with 3D: The development of high throughput...
    DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
    Speaker: Madhu Nag, PhD
    Sponsored By: Revvity
    4
    NOV 14, 2017 | 10:00 AM
    WEBINAR:  Cancer Cells Send Signals Boosting Survival and Drug Resistance in Other Cancer Cells
    WEBINAR: Cancer Cells Send Signals Boosting Survival and Drug...
    DATE: November 14, 2017TIME: 10:00am PST, 1:00pm ESTSuccessful tumor outgrowth requires the coordination of a variety of cell intrinsic and cell extrinsic signaling events. These events...
    Speaker: Jeffrey Rodvold, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco, Thermo Fisher Scientific/Gibco
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